Spontaneous mid-oesophageal rupture.

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Obesity in mid-life may increase the risk of subsequent dementia. Our objective was to study this risk, focusing on differences by age at the time of recording of obesity, in a large defined population. METHODS:A record linkage cohort study was undertaken using national administrative statistical data on hos...

journal_title：Postgraduate medical journal

authors： Wotton CJ,Goldacre MJ

更新日期：2014-10-01 00:00:00

abstract：:We report a case of persistent chorea as a manifestation of thyrotoxicosis. The chorea was severe and persisted after the patient was rendered euthyroid. Dopamine antagonists only partially suppressed the involuntary movements during the first few months. It was eventually controlled with haloperidol, but whenever she...

journal_title：Postgraduate medical journal

authors： Javaid A,Hilton DD

更新日期：1988-10-01 00:00:00

abstract：:The literature of the outbreaks of 'epidemic neuromyasthenia' (ENM) from 1934 to 1955 has been selected to show that the disease affects other people besides young adult females in hospitals and nursing homes. There have been district epidemics, in which the male: female ratio was almost even and several male outbreak...

journal_title：Postgraduate medical journal

authors： Parish JG

更新日期：1978-11-01 00:00:00

abstract：:One hundred and thirteen patients were entered into a randomized, prospective double-blind, placebo controlled trial to assess the use of co-trimoxazole in reducing wound infections after dog bites. Although there was a reduction in the wound infection rate from 13.8% in the placebo group to 5.5% in the treatment grou...

journal_title：Postgraduate medical journal

authors： Jones DA,Stanbridge TN

更新日期：1985-07-01 00:00:00

abstract：:A patient with the unusual post mortem finding of myocardial metastatic carcinoid tumour without classical valvular or endocardial carcinoid disease is described. This rare occurrence may represent an aggressive type of carcinoid tumour, with metastatic disease occurring before the development of classical fibrous val...

journal_title：Postgraduate medical journal

authors： Davis G,Birbeck K,Roberts D,Naqvi N

更新日期：1996-12-01 00:00:00

abstract：PURPOSE:Large population studies now demonstrate that frailty is prevalent in all adult age groups. Limited data exist on the association between frailty and surgical outcome in younger patients. The aim of the study was to explore the agreement between frailty identification tools and collect pilot data on their predi...

journal_title：Postgraduate medical journal

authors： Dale MacLaine T,Baker O,Burke D,Howell SJ

更新日期：2021-01-12 00:00:00

abstract：:We describe two cases of digoxin toxicity presenting with clinical and electroencephalographic evidence of encephalopathy without other features of digoxin toxicity. ...

journal_title：Postgraduate medical journal

authors： Greenaway JR,Abuaisha B,Bramble MG

更新日期：1996-06-01 00:00:00

abstract：:Upper gastrointestinal bleeding is one of the commonest emergencies encountered by general physicians. Once haemodynamic stability has been achieved, therapeutic endoscopy is vital in control and arrest of bleeding. Various methods are available and the evidence is reviewed as to the most optimal approach. Clinical pa...

journal_title：Postgraduate medical journal

authors： Arasaradnam RP,Donnelly MT

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:To explore the relationship between cognitive impairment and conventional measures of disability in multiple sclerosis (MS), quality of life (QOL) and employment status using the brief international cognitive assessment for multiple sclerosis (BICAMS) in the routine outpatient clinic. METHODS:62 patients wi...

journal_title：Postgraduate medical journal

authors： Campbell J,Rashid W,Cercignani M,Langdon D

更新日期：2017-03-01 00:00:00

abstract：:The prognosis of patients with metastatic adrenal cortical carcinoma is poor, and their disabling symptoms are usually unresponsive to conventional therapy. A patient with Cushing's syndrome secondary to a secretory adrenal cortical carcinoma was treated with octreotide, endocrine therapy and chemotherapy having faile...

journal_title：Postgraduate medical journal

authors： Pandha HS,Harrington K,Saini S,Lynn J,Peters M,Waxman J

更新日期：1995-04-01 00:00:00

abstract：:The risk of developing an overt malignancy after an isolated deep venous thrombosis (DVT) is poorly documented. We therefore reviewed a series of patients in whom a solitary idiopathic DVT had been proven by venography at least 12 months earlier. No patient had developed a malignancy at follow-up. However, decreased f...

journal_title：Postgraduate medical journal

authors： O'Connor NT,Cederholm-Williams SA,Fletcher EW,Allington M,Sharp AA

更新日期：1984-04-01 00:00:00

abstract：:Malignant hyperthermia is a rare autosomal dominant trait that predisposes affected individuals to great danger when exposed to certain anaesthetic triggering agents (such as potent volatile anaesthetics and succinylcholine). A sudden hypermetabolic reaction in skeletal muscle leading to hyperthermia and massive rhabd...

journal_title：Postgraduate medical journal

authors： Ben Abraham R,Adnet P,Glauber V,Perel A

更新日期：1998-01-01 00:00:00

abstract：:This report describes the case history of a middle-aged lady who presented with symptoms and signs over one year leading to a diagnosis of multiple sclerosis. During one of her relapses, she developed trismus--an association that has not been described before in multiple sclerosis. ...

journal_title：Postgraduate medical journal

authors： D'Costa DF,Vania AK,Millac PA

更新日期：1990-10-01 00:00:00

abstract：:Posterior leukoencephalopathy syndrome is a newly recognised brain disorder that predominantly affects the cerebral white matter. Oedematous lesions particularly involve the posterior parietal and occipital lobes, and may spread to basal ganglia, brain stem, and cerebellum. This rapidly evolving neurological condition...

journal_title：Postgraduate medical journal

authors： Garg RK

更新日期：2001-01-01 00:00:00

abstract：:A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious dise...

journal_title：Postgraduate medical journal

authors： Fernandez-Miranda C,Mateo S,Gonzalez-Gomez C,Ballestin C

更新日期：1994-07-01 00:00:00

abstract：:Treatment of angina with a single drug often proves unsatisfactory because of dose-related unwanted effects or occasionally an adverse effect on the angina. A combination of a beta-blocking agent and a calcium antagonist drug might achieve satisfactory control of angina at acceptable doses of each drug. Widespread app...

journal_title：Postgraduate medical journal

authors： Geddes JS

更新日期：1983-01-01 00:00:00

abstract：:This report deals with a patient with long standing myasthenia gravis treated with a small dose of corticosteroids. The response to treatment was prompt and the post-therapeutic deterioration in function was minimal and cholinergic in nature. It is suggested that the dose of anticholinesterases be reduced concomitantl...

journal_title：Postgraduate medical journal

authors： Dandona P,Corkan EJ,Sladen GE

更新日期：1977-06-01 00:00:00

abstract：:The abnormalities of erythrocytes, leucocytes, thrombocytes and coagulation that have been reported, particularly in more recent years, to be associated with hyperthyroidism are surveyed. Several areas are highlighted where further investigations could lead to clinically useful insights, improved information about the...

journal_title：Postgraduate medical journal

authors： Ford HC,Carter JM

更新日期：1988-10-01 00:00:00

abstract：:Herpes simplex encephalitis may be underdiagnosed in Britain. We report eight patients treated at one hospital over three years. Fever, impaired consciousness or focal neurological signs were seen in all patients at presentation but herpes simplex encephalitis was rarely considered as the initial diagnosis. The electr...

journal_title：Postgraduate medical journal

authors： Gulliford MC,Chandrasekera CP,Cooper RA,Murphy RP

更新日期：1987-12-01 00:00:00

abstract：:The anticoagulant agents heparin and warfarin were introduced before the era of randomised clinical trials. As a result, the indications, dosages and monitoring techniques of these drugs have undergone re-evaluation in multiple clinical trials in the past years. Low molecular weight heparin has been developed, which h...

journal_title：Postgraduate medical journal

authors： Toh CH

更新日期：1997-05-01 00:00:00

abstract：:This paper discusses the relationship between panic and other symptoms of anxiety disorders. The approach to classification of these disorders described in the Diagnostic and Statistical Manual of Mental Disorders (Third Edition) of the American Psychiatric Association is outlined. It is concluded that there are subst...

journal_title：Postgraduate medical journal

authors： Brandon S

更新日期：1988-01-01 00:00:00

abstract：:A patient is described who developed acute pericarditis during a severe first attack of Crohn's disease. The opportunity was taken to measure levels of circulating immune complexes, both during the acute phase of the illness and during convalescence; no significant change in these levels from normal values was found. ...

journal_title：Postgraduate medical journal

authors： Manomohan V,Subbuswamy SG,Willoughby CP

更新日期：1984-10-01 00:00:00

abstract：:Between 1975 and 1982 in 2 centres in Glasgow, 53 previously untreated patients with aggressive non-Hodgkin's lymphomas received chemotherapy consisting of one of the following regimens-CVP, MOPP, CHOP or BACOP. Twenty nine patients (55%) entered complete remission (CR), 20 (38%) had partial remission (PR) and 4 (7%) ...

journal_title：Postgraduate medical journal

authors： Cunningham D,Hepplestone A,Gilchrist NL,Dagg JH,Evans IL,Soukop M

更新日期：1987-01-01 00:00:00

abstract：:The acute haemodynamic effects of endralazine, a new hydralazine-like vasodilating agent, were studied in 6 patients with stable angina pectoris and proven coronary artery disease. Twenty minutes after intravenous administration of 5 mg endralazine heart rate and cardiac index increase, while mean arterial blood press...

journal_title：Postgraduate medical journal

authors： van der Wall EE,de Feyter PJ,Res JC,Roos JP,van Engelen CL

更新日期：1983-01-01 00:00:00

abstract：:Pneumonia due to Mycoplasma pneumoniae is common, but it is rarely life-threatening. A case is reported in a previously healthy adult whose illness was severe enough to require treatment with intermittent positive pressure ventilation (IPPV) for 14 days and which resolved after treatment with corticosteroids. ...

journal_title：Postgraduate medical journal

authors： McGonigle R,Wagstaff JK

更新日期：1980-09-01 00:00:00

abstract：:Fifty two cases of tuberculosis of the breast encountered over a 15 year period and accounting for 3% of all breast lesions are reported. The classic presentation was a breast lump with associated sinus in 39%, isolated breast lump in 23%, sinus without lump in 12%, and tender nodularity in 23% of the patients. Associ...

journal_title：Postgraduate medical journal

authors： Khanna R,Prasanna GV,Gupta P,Kumar M,Khanna S,Khanna AK

更新日期：2002-07-01 00:00:00

abstract：:Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage be...

journal_title：Postgraduate medical journal

authors： Barr GD,Shale DJ,Jewell DP

更新日期：1986-05-01 00:00:00

abstract：:Perforation of the gastrointestinal tract by ingested foreign bodies is rare; the diagnosis of pyogenic liver abscess resulting from such perforations is usually made at post-mortem. We present a case of perforation of the gut, due to an ingested dental plate, with a resultant pyogenic liver abscess, which presented a...

journal_title：Postgraduate medical journal

authors： Shaw PJ,Freeman JG

更新日期：1983-07-01 00:00:00

abstract：:Two patients with severe dothiepin intoxication are described. The management of these cases is discussed and we draw attention to the prolonged elimination half-life of dothiepin and its metabolites, and the implication for treatment. ...

journal_title：Postgraduate medical journal

authors： Bloodworth L,Wilson A,Collins P,Rainford DJ

更新日期：1984-06-01 00:00:00