Obese children and adolescents have elevated nighttime blood pressure independent of insulin resistance and arterial stiffness.

abstract：:The Captopril Prevention Project (CAPPP) is an ongoing prospective intervention study in 10,800 hypertensive patients in Sweden and Finland. Patients are randomized to treatment with either conventional antihypertensive therapy, ie, diuretics or beta-blockers, or the angiotensin-converting enzyme inhibitor captopril. ...

journal_title：American journal of hypertension

authors： Hansson L

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Hypertension and smoking independently contribute to the risk of stroke. Our objective was to investigate home blood pressure (HBP) levels, day-by-day BP variability, and smoking in the prediction of stroke in Japanese men. METHODS:In this study, 902 men (mean age, 58.6 years) without a past history of stro...

journal_title：American journal of hypertension

authors： Hashimoto T,Kikuya M,Ohkubo T,Satoh M,Metoki H,Inoue R,Asayama K,Kanno A,Obara T,Hirose T,Hara A,Hoshi H,Totsune K,Satoh H,Sato H,Imai Y

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Epidemiologic analysis of family data on blood pressure (BP) is often compromised by the effects of antihypertensive medications. A review of numerous clinical trials that investigated the effects of BP-lowering medications is summarized here. METHODS:Published clinical trials, including 137 clinical trials...

journal_title：American journal of hypertension

authors： Wu J,Kraja AT,Oberman A,Lewis CE,Ellison RC,Arnett DK,Heiss G,Lalouel JM,Turner ST,Hunt SC,Province MA,Rao DC

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:There is evidence from genome wide association study that single-nucleotide polymorphisms (SNPs) in the 5' end of the uromodulin gene (UMOD) affect uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb of the loop of Henle (TAL) and its effect on...

journal_title：American journal of hypertension

authors： McCallum L,Brooksbank K,McConnachie A,Aman A,Lip S,Dawson J,MacIntyre IM,MacDonald TM,Webb DJ,Padmanabhan S

更新日期：2020-10-21 00:00:00

abstract：:The "totality" of hypertension clinical trial endpoint data has shown that the absolute benefit of pharmacological blood pressure (BP) lowering is directly related to the BP level and baseline cardiovascular risk, albeit with attenuation of the relative risk reduction per unit of BP lowering in patients with diabetes ...

journal_title：American journal of hypertension

authors： Flack JM,Nolasco C,Levy P

更新日期：2017-01-01 00:00:00

abstract：:Conflicting reports exist as to whether air traffic controllers (ATC) have an increase in blood pressure (BP) and prevalence of hypertension because of the stressful nature of their job. We have addressed the issue in male ATC working at the Linate airport of Milan. A total of 80 ATC participated, and the 24 h blood p...

journal_title：American journal of hypertension

authors： Sega R,Cesana G,Costa G,Ferrario M,Bombelli M,Mancia G

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Considering sex differences, salt sensitivity, and insulin resistance (IR), the effect of sodium restriction and increased potassium intake on blood pressure remains unclear in normotensive Asian individuals, compared to that in hypertensive patients. METHODS:To assess the influence of sodium and potassium ...

journal_title：American journal of hypertension

authors： Murao S,Takata Y,Yasuda M,Osawa H,Kohi F

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors and calcium channel blockers (CCBs) increase arterial compliance and decrease left ventricular mass in hypertensive patients. This study examined whether combined therapy has greater arterial and cardiac effects than doubled doses of the individual drugs. METHO...

journal_title：American journal of hypertension

authors： Neutel JM,Smith DH,Weber MA

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Nocturnal hypertension is an important phenotype of abnormal diurnal blood pressure (BP) variability and a known risk marker for target organ damage and cardiovascular events. This study aimed to assess the differential BP-lowering effects of esaxerenone vs. eplerenone on nocturnal BP in hypertensive patient...

journal_title：American journal of hypertension

authors： Kario K,Ito S,Itoh H,Rakugi H,Okuda Y,Yoshimura M,Yamakawa S

更新日期：2020-11-09 00:00:00

abstract：:Blood pressure responses to 1 week of low (20 mmol sodium/day) and high (300 mmol sodium/day) salt intake were investigated in a double-blind, randomized study in 46 white, nonobese subjects with essential hypertension (13 women, 33 men; mean age 45.3 +/- 2.2 years, age range 25 to 80 years). The individuals were clas...

journal_title：American journal of hypertension

authors： Overlack A,Ruppert M,Kolloch R,Kraft K,Stumpe KO

更新日期：1995-08-01 00:00:00

abstract：:Among the major mechanisms controlling the renal release of renin, renal nerves are known to exert a direct stimulating action on juxtaglomerular cells that is mediated by beta-adrenoceptors. Activation of the renal nerves also exerts an important permissive role in order to amplify and possibly accelerate responses t...

journal_title：American journal of hypertension

authors： Stella A,Golin R,Zanchetti A

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:A modest rise in blood pressure (BP) reportedly increases cardiovascular mortality despite not reaching obvious hypertension, suggesting that target organ damages are latently induced by slight BP rising. The goal of this study was to determine whether presence of subclinical myocardial damage can predict th...

journal_title：American journal of hypertension

authors： Honda Y,Watanabe T,Tamura H,Nishiyama S,Takahashi H,Arimoto T,Shishido T,Miyamoto T,Shibata Y,Konta T,Kayama T,Kubota I

更新日期：2018-04-13 00:00:00

abstract：BACKGROUND:It is unclear whether serum uric acid (SUA) is associated with development of new-onset diabetes (NOD) in patients with hypertension and left ventricular hypertrophy (LVH). The aim of the present investigation was to test the hypothesis that SUA predicts development of NOD in these patients. METHODS:In the ...

journal_title：American journal of hypertension

authors： Wiik BP,Larstorp AC,Høieggen A,Kjeldsen SE,Olsen MH,Ibsen H,Lindholm L,Dahlöf B,Devereux RB,Okin PM,Wachtell K

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have a disproportionate risk of cardiovascular disease. This study was designed to assess the association between two noninvasive measures of cardiovascular risk, pulse wave analysis (PWA), and carotid intima-media thickness (IMT), in a cohort of CKD patients enroll...

journal_title：American journal of hypertension

authors： DeLoach SS,Appel LJ,Chen J,Joffe MM,Gadegbeku CA,Mohler ER 3rd,Parsa A,Perumal K,Rafey MA,Steigerwalt SP,Teal V,Townsend RR,Rosas SE

更新日期：2009-12-01 00:00:00

abstract：:The influence of increased lability of blood pressure on the development of aortic atherosclerosis was examined. Because sinoaortic denervation (SAD) produced increased lability of blood pressure without blood pressure elevation, the development of atheromatous plaque was examined in SAD rats. These rats were fed a hi...

journal_title：American journal of hypertension

authors： Sasaki S,Yoneda Y,Fujita H,Uchida A,Takenaka K,Takesako T,Itoh H,Nakata T,Takeda K,Nakagawa M

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:We compare patterns of blood pressure (BP) and prevalence of hypertension between white-Dutch and their South-Asian and African minority groups with their corresponding white-English and their South-Asian and African ethnic minority groups; and the contribution of physical activity, body sizes, and socioecon...

journal_title：American journal of hypertension

authors： Agyemang C,Kunst A,Bhopal R,Zaninotto P,Unwin N,Nazroo J,Nicolaou M,Redekop WK,Stronks K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:There is growing evidence that residential environment is associated with hypertension. Recently, interest has also turned toward examining the possible influence of remoteness on hypertension. The aim of this study is to explore the effect of remoteness, the shortest path between the subject location and th...

journal_title：American journal of hypertension

authors： Hamano T,Kimura Y,Takeda M,Yamasaki M,Nabika T,Shiwaku K

更新日期：2012-07-01 00:00:00

abstract：:Increased dietary K+ increases plasma [K+] and is linked to or associated with reduced mortality from stroke and reduced blood pressure in humans and animals. We hypothesized that physiologic increases in extracellular [K+] ([K]o) directly inhibit cultured vascular smooth muscle cell (VSMC) proliferation. Studies were...

journal_title：American journal of hypertension

authors： McCabe RD,Young DB

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The risk for cardiovascular events increases within hours of near-roadway exposures. We aimed to determine the traffic-related air pollution (TRAP) and biological mechanisms involved and if reducing particulate matter <2.5 µm (PM2.5) inhalation is protective. METHODS:Fifty healthy-adults underwent multiple ...

journal_title：American journal of hypertension

authors： Morishita M,Wang L,Speth K,Zhou N,Bard RL,Li F,Brook JR,Rajagopalan S,Brook RD

更新日期：2019-10-16 00:00:00

abstract：:The treatment of diseases has been based on the concept of homeostasis and has not incorporated an understanding of biologic rhythms and their underlying mechanisms. Biologic rhythms are implicated in cardiovascular events. Failure to recognize the circadian decline in blood pressure may result in iatrogenic chronopat...

journal_title：American journal of hypertension

authors： Prisant LM

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status. METHODS:Two thousand five hundred and three individuals born in 1921-1954 at the Peking Union Medical College Hospital (PUMCH) were targeted; 2,081 (83.1...

journal_title：American journal of hypertension

authors： Chen X,Zhang ZX,George LK,Wang ZS,Fan ZJ,Xu T,Zhou XL,Han SM,Wen HB,Zeng Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases. ...

journal_title：American journal of hypertension

authors： Bundy JD,Jaeger BC,Huffman MD,Knox SS,Thomas SJ,Shimbo D,Booth Iii JN,Lewis CE,Edwards LJ,Schwartz JE,Muntner P

更新日期：2020-11-17 00:00:00

abstract：:Cocaine causes acute hypertension by blocking catecholamine reuptake. There is evidence that it also impairs the peripheral endothelial nitric oxide system, which is normally vasodilatory. We further explored the role of nitric oxide in cocaine-induced vasoconstriction in anesthetized rats, and in vitro by using isola...

journal_title：American journal of hypertension

authors： Mo W,Singh AK,Arruda JA,Dunea G

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Activation of RhoA/Rho kinase (ROK) pathway by angiotensin II (Ang II) is involved in the pathophysiology of hypertension and remodeling. In Bartter's and Gitelman's syndrome (BS/GS), the short-term and long-term signaling of Ang II are blunted. The BS/GS have also reduced expression and response on Ang II c...

journal_title：American journal of hypertension

authors： Pagnin E,Semplicini A,Sartori M,Pessina AC,Calò LA

更新日期：2005-09-01 00:00:00

abstract：:In this review we have analyzed the present knowledge about the differentiation and growth processes in vascular smooth muscle cells (SMC) in hypertension. The study of smooth muscle (SM) and nonmuscle (NM) myosin isoform expression has permitted us to identify a three-stage specific maturational pathway, namely, feta...

journal_title：American journal of hypertension

authors： Pauletto P,Sarzani R,Rappelli A,Chiavegato A,Pessina AC,Sartore S

更新日期：1994-07-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs interfere with certain antihypertensive therapies. In a double-blind study, 385 hypertensive patients stabilized on an angiotensin converting enzyme inhibitor were treated with nabumetone, celecoxib, ibuprofen, or placebo for 4 weeks. Ibuprofen caused significantly greater increase...

journal_title：American journal of hypertension

authors： Palmer R,Weiss R,Zusman RM,Haig A,Flavin S,MacDonald B

更新日期：2003-02-01 00:00:00

abstract：:Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy,...

journal_title：American journal of hypertension

authors： Bottini PB,Carr AA,Prisant LM,Flickinger FW,Allison JD,Gottdiener JS

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:The "nondipping" pattern (NDP) of blood pressure, characterized by the absence of the reduction in blood pressure (BP) that typically takes place during the night time, has been associated with elevated cardiovascular morbidity, including stroke, myocardial infarction, and sudden cardiac-related death. In va...

journal_title：American journal of hypertension

authors： Myredal A,Friberg P,Johansson M

更新日期：2010-03-01 00:00:00

abstract：:The Multicenter Isradipine/Diuretic Atherosclerosis Study (MIDAS) is a randomized, double-blind, active-control trial to compare the effectiveness of two treatment regimens for the control of hypertension in reducing the rate of progression of early extracranial carotid artery atherosclerosis in hypertensive patients....

journal_title：American journal of hypertension

authors： Applegate WB,Byington RP

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:To determine all-cause and circulatory system (cardiovascular)-related mortality in subjects with different grades of hypertension, we performed a prospective study. METHODS:A total of 148,173 individuals aged > or =35 years were recruited in Mumbai, India in years 1991-1997. Clinical history and anthropome...

journal_title：American journal of hypertension

authors： Pednekar MS,Gupta R,Gupta PC

更新日期：2009-10-01 00:00:00