The role of xerostomia in burning mouth syndrome: a case-control study.

Abstract:

OBJECTIVE:To assess the efficacy of anti-xerostomic topical medication (urea 10%) in patients with burning mouth syndrome (BMS). METHOD:Thirty-eight subjects diagnosed with BMS according to the International Association for the Study of Pain guidelines were randomized to either placebo (5% sodium carboxymethylcellulose, 0.15% methyl paraben, and 10% glycerol in distilled water qsp 100 g) or treatment (urea 10%) to be applied to the oral cavity 3-4 times per day for 3 months. The patients were evaluated before and after treatment with the following instruments: the EDOF-HC protocol (Orofacial Pain Clinic - Hospital das Clínicas), a xerostomia questionnaire, and quantitative sensory testing. RESULTS:There were no differences in salivary flow or gustative, olfactory, or sensory thresholds (P>0.05). Fifteen (60%) patients reported improvement with the treatments (P=0.336). CONCLUSION:In conclusion, there were no differences between groups, and both exhibited an association between reported improvement and salivation.

journal_name

Arq Neuropsiquiatr

authors

Silva LA,Siqueira JT,Teixeira MJ,Siqueira SR

doi

10.1590/0004-282X20130218

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

91-8

issue

2

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2014000200091

journal_volume

72

pub_type

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