当前位置： SCI文献检索 > ARCHIVES OF ORAL BIOLOGY期刊下所有文献 > Alpha 2 integrin gene (ITGA2) polymorphism in renal transplant recipients with and without drug induced gingival overgrowth.

Alpha 2 integrin gene (ITGA2) polymorphism in renal transplant recipients with and without drug induced gingival overgrowth.

Abstract：

BACKGROUND:Variances in fibroblasts' α2β1 integrin intensity may lead to altered adhesion to type I collagen and consequently to suppression of phagocytosis which may be one of the mechanisms for drug induced gingival overgrowth. The present study aimed to evaluate the genotype and allele frequencies of α2 integrin +807 gene in renal transplant patients with and without gingival overgrowth. MATERIAL AND METHODS:Seventy renal transplant patients with cyclosporine A (CsA)-induced gingival overgrowth (CsA GO+) were enrolled. Renal transplant patients without GO medicated with CsA (CsA GO-; n=79) and tacrolimus (Tac; n=52) served as controls. DNA was obtained from peripheral blood and ITGA2 +807C/T polymorphism was genotyped by polymerase chain reaction and restriction fragment length polymorphism method. Clinical parameters including probing depth and plaque, papilla bleeding and hyperplasia indexes were recorded. Chi-square, Kruskal-Wallis and Mann-Whitney tests were used in statistical analysis. RESULTS:Clinical parameters of CsA GO+ group were significantly higher than those of the CsA GO- and Tac groups (p<0.05). ITGA2 807C/T genotype and allele frequencies of study groups were similar (p>0.05). CONCLUSION:Within the limits of the present study it can be concluded that ITGA2 +807 gene polymorphism is not associated with susceptibility to CsA-induced GO.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Gürkan A,Emingil G,Afacan B,Berdeli A,Atilla G

doi

10.1016/j.archoralbio.2013.12.003

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

283-8

issue

3

eissn

0003-9969

issn

1879-1506

pii

S0003-9969(13)00358-0

journal_volume

59

pub_type

杂志文章

相关文献

ARCHIVES OF ORAL BIOLOGY文献大全
  • The relationship between IgA antibodies to Streptococcus mutans antigens in human saliva and breast milk and the numbers of indigenous oral Streptococcus mutans.

    abstract：:The influence of indigenous Streptococcus mutans on naturally-occurring levels of IgA antibodies was studied in 42 lactating females. Breast milk, parotid and whole-saliva samples were collected and analysed by the ELISA method for IgA antibodies, reacting with antigens from Strep. mutans. All salivas and breast milk ...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(87)90149-x

    authors： Camling E,Gahnberg L,Krasse B

    更新日期：1987-01-01 00:00:00

  • Intracellular trafficking and surface expression of SS-A (Ro), SS-B (La), poly(ADP-ribose) polymerase and alpha-fodrin autoantigens during apoptosis in human salivary gland cells induced by tumour necrosis factor-alpha.

    abstract：:Autoantibodies directed against nucleic acid and protein complexes present in cell nuclei characterize autoimmune diseases and are employed in diagnosis. The mechanisms by which these autoantigens escape immunological tolerance are largely unknown, but a number of recent observations suggest that modified self-protein...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/s0003-9969(02)00025-0

    authors： McArthur C,Wang Y,Veno P,Zhang J,Fiorella R

    更新日期：2002-06-01 00:00:00

  • Risk factors of oral candidosis: a twofold approach of study by fuzzy logic and traditional statistic.

    abstract：OBJECTIVE:To assess a panel of risk factors associated to oral candidosis (OC) onset and its chronic maintenance by means of fuzzy logic (FL) approach and statistical traditional methodology (STM); to investigate their casual relationship within a multifactorial framework. DESIGN:Case-control study. SETTING:One hospi...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2007.11.009

    authors： Campisi G,Panzarella V,Matranga D,Calvino F,Pizzo G,Lo Muzio L,Porter S

    更新日期：2008-04-01 00:00:00

  • Sophoraflavanone G prevents Streptococcus mutans surface antigen I/II-induced production of NO and PGE2 by inhibiting MAPK-mediated pathways in RAW 264.7 macrophages.

    abstract：BACKGROUND:Sophora flavescens AITON (Leguminosae) is a typical traditional Korean medical herb considered to exhibit antibacterial, anti-inflammatory, and antipyretic effects, and is also used for the treatment of skin and mucosal ulcers, sores, diarrhea, gastrointestinal hemorrhage, arrhythmia, and eczema. OBJECTIVE ...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2016.04.001

    authors： Cha SM,Cha JD,Jang EJ,Kim GU,Lee KY

    更新日期：2016-08-01 00:00:00

  • Developmental characteristics of secondary cartilage in the mandibular condyle and sphenoid bone in mice.

    abstract：OBJECTIVE:Secondary cartilage develops from osteochondral progenitor cells. Hypertrophic chondrocytes in secondary cartilage increase within a very short time and then ossify rapidly. In the present study, we investigated the sequential development process of osteochondral progenitor cells, and the morphology and size ...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2017.12.027

    authors： Hirouchi H,Kitamura K,Yamamoto M,Odaka K,Matsunaga S,Sakiyama K,Abe S

    更新日期：2018-05-01 00:00:00

  • An immunohistochemical study of the expression of heat-shock protein-25 and cell proliferation in the dental pulp and enamel organ during odontogenesis in rat molars.

    abstract：OBJECTIVES:The aim of this study is to clarify the functional significance of heat-shock protein (HSP)-25 during tooth development. DESIGN:We compared the expression of HSP-25 in the dental epithelial and mesenchymal cells with their proliferative activity during odontogenesis in rat molars on postnatal days 1-100 by ...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2005.09.007

    authors： Nakasone N,Yoshie H,Ohshima H

    更新日期：2006-05-01 00:00:00

  • Prediction of periodontopathic bacteria in dental plaque of periodontal healthy subjects by measurement of volatile sulfur compounds in mouth air.

    abstract：OBJECTIVES:The aim of this study was to determine whether measurements of volatile sulfur compounds (VSCs) are useful to predict colonization of periodontopathic bacteria. For this purpose, we assessed the relationships among distributions of 4 species of periodontopathic bacteria in tongue coating and dental plaque, o...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2012.09.019

    authors： Kishi M,Ohara-Nemoto Y,Takahashi M,Kishi K,Kimura S,Aizawa F,Yonemitsu M

    更新日期：2013-03-01 00:00:00

  • Expression of Pannexin3 in human odontoblast-like cells and its hemichannel function in mediating ATP release.

    abstract：OBJECTIVE:The aim of this study is to investigate the expression of pannexin3 (Panx3) in human odontoblast-like cells (hOBs) and its hemichannel function in mediating ATP release. METHODS:RT-PCR and immunofluorescence analysis were used to detect the expression of pannexins (Panxs) in human dental pulp tissue and cult...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2015.07.005

    authors： Fu D,Song F,Sun H,Pei D,Wang Y,Lei J,Huang C

    更新日期：2015-10-01 00:00:00

  • Jumonji domain-containing protein 3 regulates the early inflammatory response epigenetically in human periodontal ligament cells.

    abstract：OBJECTIVE:To investigate the role of the histone 3 lysine 27 trimethylation (H3K27me3) demethylase Jumonji domain-containing protein 3 (Jmjd3) in the epigenetic regulation of the inflammatory response in human periodontal ligament cells (HPDLs). DESIGN:HPDLs were stimulated with lipopolysaccharide from E. coli. The ex...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2018.05.007

    authors： Wang P,Yue J,Xu W,Chen X,Yi X,Ye L,Zhang L,Huang D

    更新日期：2018-09-01 00:00:00

  • Anti-caries effect of fluoridated milk-based drink consumed by older adults on an in vitro root caries experimental model.

    abstract：OBJECTIVE:This study aimed to evaluate the anti-caries effect of a fluoridated milk-based drink on a root caries model by assessing mineral loss and both biofilm microbial viability and acidogenicity under increasing concentrations of fluoride supplementation. DESIGN:Streptococcus mutans UA159 biofilms were grown on r...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2020.104878

    authors： Castro RJ,Maltz M,Arthur RA,Giacaman RA

    更新日期：2020-10-01 00:00:00

  • Chewing chitosan-containing gum effectively inhibits the growth of cariogenic bacteria.

    abstract：OBJECTIVE:We have already reported that chitosan inhibited the growth of cariogenic bacteria in vitro. This study was designed to evaluate whether chewing gum, containing chitosan, can effectively suppressed the growth of oral bacteria (total bacteria, total Streptococci, mutans streptococci (MS)) in saliva. METHODS:F...

    journal_title：Archives of oral biology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.archoralbio.2006.10.004

    authors： Hayashi Y,Ohara N,Ganno T,Yamaguchi K,Ishizaki T,Nakamura T,Sato M

    更新日期：2007-03-01 00:00:00

  • Endocannabinoids mediate hyposalivation induced by inflammogens in the submandibular glands and hypothalamus.

    abstract：OBJECTIVE:The aim of this study was to investigate the factors that could participate on salivary glands hypofunction during inflammation and the participation of endocannabinoids in hyposalivation induced by the presence of inflammogens in the submandibular gland (SMG) or in the brain. DESIGN:Salivary secretion was a...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2013.04.003

    authors： Prestifilippo JP,Medina VA,Mohn CE,Rodriguez PA,Elverdin JC,Fernandez-Solari J

    更新日期：2013-09-01 00:00:00

  • Biological markers for evaluation of root resorption.

    abstract：BACKGROUND:External apical root resorption is a pathologic consequence of orthodontic tooth movement. Cementum and dentin are removed from the root surface while active force is present. OBJECTIVE:The aim of this study was to identify and quantify extracellular matrix proteins, dentin matrix protein 1 (DMP1), dentin p...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2006.08.018

    authors： Balducci L,Ramachandran A,Hao J,Narayanan K,Evans C,George A

    更新日期：2007-03-01 00:00:00

  • Neonatal lines in the enamel of primary teeth--a morphological and scanning electron microscopic investigation.

    abstract：OBJECTIVE:The neonatal line (NNL) is in principle found in all primary teeth and the line represents the time of birth. Earlier findings of the appearance of the NNL in light microscope and in microradiographs have shown not only changes in the prism direction of the enamel, but that the NNL has a hypomineralized chara...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2008.05.003

    authors： Sabel N,Johansson C,Kühnisch J,Robertson A,Steiniger F,Norén JG,Klingberg G,Nietzsche S

    更新日期：2008-10-01 00:00:00

  • Purification and characterization of subunits of a high molecular weight human salivary mucin.

    abstract：:A high molecular-weight mucin was purified from human submandibular-sublingual saliva. The purity of the mucin preparation was demonstrated by the absence of other salivary proteins, by antibody reactivity and by gel electrophoresis. After reduction with mercaptoethanol a putative link component with approximate Mr 15...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(90)90041-8

    authors： Kawagishi S,Fahim RE,Wong KH,Bennick A

    更新日期：1990-01-01 00:00:00

  • Collagenolytic and phosphatase activity in the rat mandible after functional protrusion.

    abstract：:The effect of chronic mandibular protrusion on the collagenolytic and phosphatase activity of several mandibular bone sites and the condylar cartilage was evaluated. Ninety-three male Sprague-Dawley rats were equally divided into two experimental and one control group. One experimental group wore a protrusive applianc...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(89)90067-8

    authors： Bollen AM,Makinen KK,Makinen PL,Carlson DS

    更新日期：1989-01-01 00:00:00

  • Synovial TRPV1 is upregulated by 17-β-estradiol and involved in allodynia of inflamed temporomandibular joints in female rats.

    abstract：:Women with reproductive capability are more likely to suffer from temporomandibular disorders (TMD), with orofacial pain as the most common complaint. In the past, we focused on the role of estradiol in TMD pain through the nervous system. In this study, we explored estradiol's influence on synoviocyte gene expression...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2015.05.011

    authors： Wu YW,Hao T,Kou XX,Gan YH,Ma XC

    更新日期：2015-09-01 00:00:00

  • Aqueous extract of Chrysanthemum morifolium Ramat. inhibits RANKL-induced osteoclast differentiation by suppressing the c-fos/NFATc1 pathway.

    abstract：OBJECTIVE:The flower of chrysanthemum, used worldwide as a medicinal and edible product, has shown various bioactivities, such as anti-inflammatory, antioxidant, anti-tumorigenic, and hepatoprotective activities, as well as cardiovascular protection. However, the effect of Chrysanthemum morifolium Ramat. on the regulat...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2020.105029

    authors： Jang HY,Lee HS,Noh EM,Kim JM,You YO,Lee G,Koo JH,Lim H,Ko S,Kim JS,Lee JH,Lee YR

    更新日期：2021-02-01 00:00:00

  • Acute stress reduces blood flow in the orofacial area, in conscious rabbits.

    abstract：:In the complex neurovascular control of the orofacial area, the only vasoconstrictor action is mediated by the sympathetic nervous system; however, its functional role is still unclear as little evidence exists of vasoconstrictor responses to physiological stimuli in both animal and human models. Aim of the present st...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2009.01.003

    authors： Roatta S,Mohammed M,Passatore M

    更新日期：2009-04-01 00:00:00

  • Low dose propranolol decreases orthodontic movement.

    abstract：OBJECTIVE:Low dose propranolol has previously been demonstrated to suppress bone remodelling. Therefore, its effect on orthodontic movement was tested. DESIGN:Rats were assigned as follows (n=5): animals with no orthodontic appliance (G1); the remaining groups were fitted with a Ni-Ti closed-coil spring ligated to the...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2014.06.006

    authors： de Oliveira EL,Freitas FF,de Macedo CG,Clemente-Napimoga JT,Silva MB,Manhães LR Jr,Junqueira JL,Napimoga MH

    更新日期：2014-10-01 00:00:00

  • The effect of short-term tooth intrusion on human pulpal blood flow measured by laser Doppler flowmetry.

    abstract：:The purpose was to examine the effect of brief intrusive forces on human pulpal blood flow (PBF). Laser Doppler flowmetric measurements were made from 17 vital upper left central incisors of 17 participants who had clinically healthy tooth crowns and periodontal tissues. Brief intrusive forces (0.5,1,5 N; duration 20 ...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/s0003-9969(01)00049-8

    authors： Ikawa M,Fujiwara M,Horiuchi H,Shimauchi H

    更新日期：2001-09-01 00:00:00

  • FGF-2 induces proliferation of human periodontal ligament cells and maintains differentiation potentials of STRO-1(+)/CD146(+) periodontal ligament cells.

    abstract：:The presence of human STRO-1(+)/CD146(+) periodontal ligament (PDL) cells has been reported, but obtaining a large amount of these cells is difficult. The purpose of this study was to evaluate the percentages of STRO-1(+)/CD146(+) cells in PDL cells and determine the effects of FGF-2 on the proliferation and multiline...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2011.12.003

    authors： Hidaka T,Nagasawa T,Shirai K,Kado T,Furuichi Y

    更新日期：2012-06-01 00:00:00

  • Photoactivated disinfection of Streptococcus intermedius through dentin disc at clinically relevant intervals: an in vitro study.

    abstract：:In this present study we have tested the impact of porfimer sodium (Photofrin, AXCAN PHARMA Inc., Quebec, Canada) photoactivated disinfection (PD) on cells of Streptococcus intermedius in suspension. In order to provide basic data to support future clinical studies of PD in dentistry the study used exposure to Quartz-...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2010.07.003

    authors： Bonstein T,Mikulski LM,Bush MA,Bush PJ

    更新日期：2010-10-01 00:00:00

  • Mechanical properties of foods responsible for resisting food breakdown in the human mouth.

    abstract：:The fragmentation of foods (breakage function) was measured in five humans on "bagged' single particles of 28 foods from three food groups. The change in the square root of the specific surface of the particles (the specific surface being the area of particle silhouettes, measured by image analysis, divided by origina...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/s0003-9969(96)00102-1

    authors： Agrawal KR,Lucas PW,Prinz JF,Bruce IC

    更新日期：1997-01-01 00:00:00

  • The relationship between water-borne fluoride, dental fluorosis and skeletal development in 11-15 year old Tanzanian girls.

    abstract：:Dental fluorosis was evaluated by a classification system, previously shown to be sensitive, and skeletal changes evaluated by bone maturity and structure. Dental fluorosis was more severe in posterior than in anterior teeth in both jaws irrespective of fluoride concentration of the drinking water. There appeared to b...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(82)90004-8

    authors： Wenzel A,Thylstrup A,Melsen B,Fejerskov O

    更新日期：1982-01-01 00:00:00

  • Crevicular fluid levels of TGFbeta1 in drug-induced gingival overgrowth.

    abstract：OBJECTIVE:To determine if local, gingival crevicular fluid (GCF) levels of TGFbeta1 were altered in drug-induced gingival overgrowth. PATIENTS AND METHODS:GCF samples were collected on Periopaper strips from 45 renal transplant recipients who had been medicated with cyclosporin or cyclosporin in combination with other...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/j.archoralbio.2003.09.002

    authors： Wright HJ,Chapple IL,Blair F,Matthews JB

    更新日期：2004-05-01 00:00:00

  • A working-side change to lateral tooth guidance increases lateral pterygoid muscle activity.

    abstract：UNLABELLED:The inferior head of lateral pterygoid (IHLP) is thought to play a critical role in the generation and control of lateral jaw movements. AIM:The aim was to test the hypothesis that a change to the lateral tooth guidance (working-side occlusal alteration, OA) results in a significant change in the electromyo...

    journal_title：Archives of oral biology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.archoralbio.2006.01.007

    authors： Huang BY,Whittle T,Murray GM

    更新日期：2006-08-01 00:00:00

  • A scanning electron microscopic and polarized light microscopic study of acid-etching of caries-like lesions in human tooth enamel treated with sodium fluoride in vitro.

    abstract：:Types of etching patterns and histological appearances were examined in acid-etched, NaF-treated caries-like lesions of enamel. Etching patterns similar to those for etched-sound enamel were found. Remineralization was limited to the surface zone and superficial portion of the body of the lesion following acid-etching...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(84)90004-9

    authors： Hicks MJ,Silverstone LM,Flaitz CM

    更新日期：1984-01-01 00:00:00

  • The surface structure of the epithelium of the hamster cheek pouch.

    abstract：:Cheek pouches were removed from 9 BIO 87.20 adult-male hamsters, pinned out on cork sheets and fixed, then divided into segments and processed. Mallory stain showed complete orthokeratinization of the pouch epithelium with regular keratohyaline granules. With scanning electron microscopy, the morphology of the walls w...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(82)90185-6

    authors： McMillan MD,Smillie AC,Gray DW

    更新日期：1982-01-01 00:00:00

  • In-vitro urea-dependent pH-changes by human salivary bacteria and dispersed, artificial-mouth, bacterial plaques.

    abstract：:The pH effects of urea metabolism were studied in washed salivary-sediment bacteria from subjects that had up to 10-fold variation in oral ureolytic activity, and in dispersed artificial-mouth plaques. Adequate evaluation required analysis of the [OH-] as well as the pH curve. An initial constant rate of pH-change, la...

    journal_title：Archives of oral biology

    pub_type： 杂志文章

    doi：10.1016/0003-9969(87)90132-4

    authors： Sissons CH,Cutress TW

    更新日期：1987-01-01 00:00:00