Effect of virginiamycin on the growth cycle of Bdellovibrio.

abstract：:In 2016, we identified a new class A carbapenemase, VCC-1, in a nontoxigenic Vibrio cholerae strain that had been isolated from retail shrimp imported into Canada for human consumption. Shortly thereafter, seven additional VCC-1-producing V. cholerae isolates were recovered along the German coastline. These isolates a...

journal_title：Antimicrobial agents and chemotherapy

authors： Mangat CS,Vadlamani G,Holicek V,Chu M,Larmour VLC,Vocadlo DJ,Mulvey MR,Mark BL

更新日期：2019-03-27 00:00:00

abstract：:The epidemiology of the two common erythromycin resistance methylase (erm) genes ermA and ermC was analyzed by Southern blotting in 428 erythromycin-resistant Staphylococcus aureus strains isolated from blood between 1959 and 1988 in Denmark. ermA and/or ermC was present in 98% of the erythromycin-resistant strains te...

journal_title：Antimicrobial agents and chemotherapy

authors： Westh H,Hougaard DM,Vuust J,Rosdahl VT

更新日期：1995-02-01 00:00:00

abstract：:The occurrence and diversity of vancomycin-resistant Enterococcus faecium (VREF) were investigated in 100 Danish broiler flocks 15 years after the avoparcin ban. VREF occurred in 47 flocks at low fecal concentrations detectable only by selective enrichment. Vancomycin resistance was prevalently associated with a trans...

journal_title：Antimicrobial agents and chemotherapy

authors： Bortolaia V,Mander M,Jensen LB,Olsen JE,Guardabassi L

更新日期：2015-05-01 00:00:00

abstract：:We evaluated the in vitro activity of piperacillin alone or in combination with the beta-lactamase inhibitor tazobactam against clinical isolates of Legionella species. At an inoculum of approximately 10(4) CFU, tazobactam, piperacillin, and the 8:1 combination had equivalent activities against Legionella spp. At an a...

journal_title：Antimicrobial agents and chemotherapy

authors： Collins LA,Wennersten CB,Ferraro MJ,Moellering RC Jr,Eliopoulos GM

更新日期：1994-01-01 00:00:00

abstract：:MUC7 12-mer-L exhibits potent in vitro antifungal activity in low-ionic-strength buffers. In this study, we investigated the anticandidal activity and stability of MUC7 12-mer-L and its all-D-amino-acid isomer, along with Hsn5 12-mer (P113) and magainin-II, in human clarified and unclarified saliva in the absence or p...

journal_title：Antimicrobial agents and chemotherapy

authors： Wei GX,Bobek LA

更新日期：2005-06-01 00:00:00

abstract：:The iron-chelating drug deferoxamine (DFO) has been shown to be active in animal models of Pneumocystis carinii pneumonia (PCP), with effective daily intraperitoneal bolus dosages being 400 and 1,000 mg of DFO mesylate kg of body weight-1 in mouse and rat models, respectively. Continuous infusion produced a moderately...

journal_title：Antimicrobial agents and chemotherapy

authors： Merali S,Chin K,Del Angel L,Grady RW,Armstrong M,Clarkson AB Jr

更新日期：1995-09-01 00:00:00

abstract：:A DNA probe was developed by inserting, in the SmaI site of pBluescript sK, a 528-bp fragment of the gene responsible for intrinsic resistance to beta-lactam antibiotics in Staphylococcus aureus (mec determinant). The mec probe provided a useful tool for the rapid identification of the intrinsic resistance trait and f...

journal_title：Antimicrobial agents and chemotherapy

authors： Ligozzi M,Rossolini GM,Tonin EA,Fontana R

更新日期：1991-03-01 00:00:00

abstract：:The quinone antibiotic streptonigrin is believed to kill bacteria by promoting formation of oxygen radicals. This antibiotic has also been used to select resistant bacterial mutants, some of which vary in iron utilization. We examined the effects of streptonigrin on Neisseria gonorrhoeae and several types of gonococca...

journal_title：Antimicrobial agents and chemotherapy

authors： Cohen MS,Chai Y,Britigan BE,McKenna W,Adams J,Svendsen T,Bean K,Hassett DJ,Sparling PF

更新日期：1987-10-01 00:00:00

abstract：:Carbapenem resistance rates in Pseudomonas aeruginosa isolates in Colombia, as in many South American countries, are high for reasons that remain unclear. From our nationwide network, we describe the first detection of the metallo-beta-lactamase VIM-2 in clinical isolates of P. aeruginosa from multiple cities within C...

journal_title：Antimicrobial agents and chemotherapy

authors： Villegas MV,Lolans K,del Rosario Olivera M,Suarez CJ,Correa A,Queenan AM,Quinn JP,Colombian Nosocomial Resistance Study Group.

更新日期：2006-01-01 00:00:00

abstract：:Biapenem is a parenteral carbapenem antibiotic that exhibits wide-ranging antibacterial activity, remarkable chemical stability, and extensive stability against human renal dehydropeptidase-I. Tebipenem is the active form of tebipenem pivoxil, a novel oral carbapenem antibiotic that has a high level of bioavailability...

journal_title：Antimicrobial agents and chemotherapy

authors： Yamada M,Watanabe T,Baba N,Takeuchi Y,Ohsawa F,Gomi S

更新日期：2008-06-01 00:00:00

abstract：:In an effort to discover novel, noncarbohydrate inhibitors of influenza virus neuraminidase we hypothesized that compounds which contain positively charged amino groups in an appropriate position to interact with the Asp 152 or Tyr 406 side chains might be bound tightly by the enzyme. Testing of 300 alpha- and beta-am...

journal_title：Antimicrobial agents and chemotherapy

authors： Kati WM,Montgomery D,Maring C,Stoll VS,Giranda V,Chen X,Laver WG,Kohlbrenner W,Norbeck DW

更新日期：2001-09-01 00:00:00

abstract：:Levofloxacin is an antituberculosis drug with substantial interindividual pharmacokinetic variability; therapeutic drug monitoring (TDM) could therefore be helpful to improve treatment results. TDM would be more feasible with limited sampling strategies (LSSs), a method to estimate the area under the concentration cur...

journal_title：Antimicrobial agents and chemotherapy

authors： van den Elsen SHJ,Sturkenboom MGG,Van't Boveneind-Vrubleuskaya N,Skrahina A,van der Werf TS,Heysell SK,Mpagama S,Migliori GB,Peloquin CA,Touw DJ,Alffenaar JC

更新日期：2018-11-26 00:00:00

abstract：:The efficacy of a loading dose of 20 mg of chloroquine per kg of body weight per os given at intervals during the first day was evaluated in 27 patients in Madagascar with Plasmodium falciparum malaria. The conventional regimen of 25 mg/kg over 3 days (schedule 1) was thus compared with a regimen of 30 mg/kg over 2 da...

journal_title：Antimicrobial agents and chemotherapy

authors： Pussard E,Lepers JP,Clavier F,Raharimalala L,Le Bras J,Frisk-Holmberg M,Bergqvist Y,Verdier F

更新日期：1991-03-01 00:00:00

abstract：:Mycograb (NeuTec Pharma plc) is a human genetically recombinant antibody against fungal heat shock protein 90 (HSP90). Antibody to HSP90 is closely associated with recovery in patients with invasive candidiasis who are receiving amphotericin B (AMB). Using in vitro assays developed for efficacy assessment of chemother...

journal_title：Antimicrobial agents and chemotherapy

authors： Matthews RC,Rigg G,Hodgetts S,Carter T,Chapman C,Gregory C,Illidge C,Burnie J

更新日期：2003-07-01 00:00:00

abstract：:Invasive pulmonary aspergillosis (IPA) is a devastating disease of immunocompromised patients. Pharmacodynamic (PD) examination of antifungal drug therapy in IPA is one strategy that may improve outcomes. The current study explored the PD target of posaconazole in an immunocompromised murine model of IPA against 10 A....

journal_title：Antimicrobial agents and chemotherapy

authors： Lepak AJ,Marchillo K,Vanhecker J,Andes DR

更新日期：2013-01-01 00:00:00

abstract：:The in vitro interactions between amikacin, netilmicin, tobramycin, gentamicin, and various antipseudomonal beta-lactams were studied by the agar dilution checkerboard technique against 30 Pseudomonas aeruginosa strains resistant to all tested antibiotics. Amikacin produced more frequent synergy both at the total and ...

journal_title：Antimicrobial agents and chemotherapy

authors： Giamarellou H,Zissis NP,Tagari G,Bouzos J

更新日期：1984-04-01 00:00:00

abstract：:Clinical isolates of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases or plasmid-mediated AmpC beta-lactamases were screened for qnrA and qnrB genes. QnrB was present in 54 of 54 DHA-1-producing K. pneumoniae isolates and 10 of 45 SHV-12-producing ones, suggesting that the distrib...

journal_title：Antimicrobial agents and chemotherapy

authors： Pai H,Seo MR,Choi TY

更新日期：2007-01-01 00:00:00

abstract：:The therapeutic effect of intranasally administered enviroxime was tested against naturally occurring common colds. The double-blind evaluation was carried out in Tecumseh, Mich., during a period when rhinoviruses are usually the principal pathogen. Rhinovirus transmission followed the typical pattern during this peri...

journal_title：Antimicrobial agents and chemotherapy

authors： Miller FD,Monto AS,DeLong DC,Exelby A,Bryan ER,Srivastava S

更新日期：1985-01-01 00:00:00

abstract：:Chromatographic fractionation of streptovaricin complex yields two stable components enriched (4- to 16-fold) in activity directed against the polycythemic strain of Friend virus; both components apparently contain no streptovaricins. When compared with their unfractionated parent streptovaricin complex, eight individ...

journal_title：Antimicrobial agents and chemotherapy

authors： Horoszewicz JS,Rinehart KL Jr,Leong SS,Carter WA

更新日期：1975-03-01 00:00:00

abstract：:Endoplasmic reticulum (ER)-resident glucosidases I and II sequentially trim the three terminal glucose moieties on the N-linked glycans attached to nascent glycoproteins. These reactions are the first steps of N-linked glycan processing and are essential for proper folding and function of many glycoproteins. Because m...

journal_title：Antimicrobial agents and chemotherapy

authors： Zhao X,Guo F,Comunale MA,Mehta A,Sehgal M,Jain P,Cuconati A,Lin H,Block TM,Chang J,Guo JT

更新日期：2015-01-01 00:00:00

abstract：:The in vitro activities of the new triazole, ravuconazole (BMS-207147), were compared to those of fluconazole and itraconazole against 541 clinical isolates of Cryptococcus neoformans. Isolates were obtained from cerebrospinal fluid (396), blood (116), and miscellaneous clinical specimens (29). Overall, ravuconazole (...

journal_title：Antimicrobial agents and chemotherapy

authors： Yamazumi T,Pfaller MA,Messer SA,Houston A,Hollis RJ,Jones RN

更新日期：2000-10-01 00:00:00

abstract：:β-Lactams are often used to treat Helicobacter cinaedi infections; however, the mechanism underlying β-lactam resistance is unknown. In this study, we investigated β-lactam resistance in an H. cinaedi strain, MRY12-0051 (MICs of amoxicillin [AMX] and ceftriaxone [CRO], 32 and 128 μg/ml; obtained from human feces). Bas...

journal_title：Antimicrobial agents and chemotherapy

authors： Rimbara E,Mori S,Kim H,Suzuki M,Shibayama K

更新日期：2018-01-25 00:00:00

abstract：:Eight healthy male volunteers received 1 g of either ceftazidime or cefamandole as an intravenous infection. Serial blood samples were taken over the next 8 h. Urine samples were collected over 24 h. Levels of these antibiotics were measured in the fluid of blisters resulting from application of cantharides. The conce...

journal_title：Antimicrobial agents and chemotherapy

authors： Armstrong GC,Wise R,Brown RM,Hancox J

更新日期：1981-09-01 00:00:00

abstract：:When strains harboring R factor and showing ampicillin (APC) resistance were inoculated on plates containing various concentrations of APC, mutants carrying various levels of APC resistance occurred at high frequencies. Increases in the level of APC resistance were due to a quantitative increase in the formation of pe...

journal_title：Antimicrobial agents and chemotherapy

authors： Odakura Y,Tanaka T,Hashimoto H,Mitsuhashi S

更新日期：1973-03-01 00:00:00

abstract：:Acinetobacter baumannii has emerged as a serious problematic pathogen due to the ever-increasing presence of antibiotic resistance, demonstrating a need for novel, broad-spectrum antimicrobial therapeutic options. Antimicrobial nanoemulsions are emulsified mixtures of detergent, oil, and water (droplet size, 100 to 80...

journal_title：Antimicrobial agents and chemotherapy

authors： Hwang YY,Ramalingam K,Bienek DR,Lee V,You T,Alvarez R

更新日期：2013-08-01 00:00:00

abstract：:The activity of gemifloxacin against Haemophilus influenzae and Moraxella catarrhalis was compared to those of 11 other agents. All quinolones were very active (MICs,

journal_title：Antimicrobial agents and chemotherapy

authors： Davies TA,Kelly LM,Hoellman DB,Ednie LM,Clark CL,Bajaksouzian S,Jacobs MR,Appelbaum PC

更新日期：2000-03-01 00:00:00

abstract：:Bacterial adaptation to external stresses and toxic compounds is a key step in the emergence of multidrug-resistant strains that are a serious threat to human health. Although some of the proteins and regulators involved in antibiotic resistance mechanisms have been described, no information is available to date conce...

journal_title：Antimicrobial agents and chemotherapy

authors： Dupont M,James CE,Chevalier J,Pagès JM

更新日期：2007-09-01 00:00:00

abstract：:Nocardia farcinica, one of the most frequent pathogenic species responsible for nocardiosis, is characterized by frequent brain involvement and resistance to β-lactams mediated by a class A β-lactamase. Kinetic parameters for hydrolysis of various β-lactams by FARIFM10152 from strain IFM 10152 were determined by spect...

journal_title：Antimicrobial agents and chemotherapy

authors： Lebeaux D,Ourghanlian C,Dorchène D,Soroka D,Edoo Z,Compain F,Arthur M

更新日期：2020-01-27 00:00:00

abstract：:wALADin1 benzimidazoles are specific inhibitors of δ-aminolevulinic acid dehydratase from Wolbachia endobacteria of filarial nematodes. We report that wALADin1 and two derivatives killed blood stage Plasmodium falciparum in vitro (50% inhibitory concentrations, 39, 7.7, and 12.8 μM, respectively). One of these derivat...

journal_title：Antimicrobial agents and chemotherapy

authors： Lentz CS,Sattler JM,Fendler M,Gottwalt S,Halls VS,Strassel S,Arriens S,Hannam JS,Specht S,Famulok M,Mueller AK,Hoerauf A,Pfarr KM

更新日期：2015-01-01 00:00:00

abstract：:A plant pathogenic actinomycete identified as Streptomyces lydicus was isolated from the deep-pitted scab lesions of potato tubers. This strain produces a new polypeptide antibiotic named chandramycin. The antibiotic was isolated from culture broth by extraction with organic solvents and purified by chromatography. Th...

journal_title：Antimicrobial agents and chemotherapy

authors： Singh SK,Gurusiddaiah S

更新日期：1984-09-01 00:00:00