Abstract：
BACKGROUND:Parkinson's disease (PD) differs from atypical parkinsonism in many clinical aspects. Principally, posture and gait are distinct features in the early stages of the disease; thus, these differences can be helpful in differential diagnosis. METHODS:We analyzed videos of patients with PD or atypical parkinsonism. A total of 76 patients with early PD (n=56) or atypical parkinsonism (n=20) were included. Items related to posture and gait were classified into three categories (standing, gait and associated symptoms) and each sub-item was analyzed. RESULTS:Asymmetric arm-swing (p=0.004) and accompanying tremor (p=0.016) were significant indicators of early-stage PD. Staggering gait (p=0.007) and en-bloc turning (p=0.026) were more common in atypical parkinsonism. Characteristics with a high odds-ratio for atypical parkinsonism were en-bloc turning (β=8.475, p=0.032) and normal arm-swing (β=14.6084, p=0.036). CONCLUSIONS:Visual inspection of gait and posture provides reliable clues in the differential diagnosis of parkinsonism.
journal_name
Gait Posturejournal_title
Gait & postureauthors
Lee SM,Kim M,Lee HM,Kwon KY,Kim HT,Koh SBdoi
10.1016/j.gaitpost.2014.01.004subject
Has Abstractpub_date
2014-04-01 00:00:00pages
1138-41issue
4eissn
0966-6362issn
1879-2219pii
S0966-6362(14)00007-1journal_volume
39pub_type
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