Glucocorticoids and stress: permissive and suppressive actions.

abstract：:The strategy of antigenic variation is to present a constantly changing population phenotype that enhances parasite transmission, through evasion of immunity arising within, or existing between, host animals. Trypanosome antigenic variation occurs through spontaneous switching among members of a silent archive of many...

journal_title：Annals of the New York Academy of Sciences

authors： Barry JD,Hall JP,Plenderleith L

更新日期：2012-09-01 00:00:00

abstract：:The aim of this study was to clarify the role of nitric oxide (NO) and lipid peroxidation (LPO) processes as well as the contribution of various neurotransmitters in pathophysiological mechanisms of neurotoxicity induced by amphetamine (AMPH). NO level was determined directly in brain tissues using electron paramagnet...

journal_title：Annals of the New York Academy of Sciences

authors： Bashkatova V,Kraus MM,Vanin A,Hornick A,Prast H

更新日期：2004-10-01 00:00:00

abstract：:Thymic tolerance depends on induction of apoptosis (programmed cell death) in immature thymocytes by antigen/MHC complexes on dendritic cells (and possibly other bone marrow-derived APCs). Interactions with antigen/MHC complexes on thymic epithelial cells promote maturation of double-positive thymocytes to single-posi...

journal_title：Annals of the New York Academy of Sciences

authors： Owen JJ,Jenkinson EJ

更新日期：1992-11-21 00:00:00

abstract：:The success of embryonic implantation relies on an ideal cross-talk between the embryo and the receptive endometrium. This article focuses on the role of leukemia inhibitory factor (LIF) and its receptors in human embryo implantation. LIF is a secreted glycoprotein first described as a factor that induced the differen...

journal_title：Annals of the New York Academy of Sciences

authors： Aghajanova L

更新日期：2004-12-01 00:00:00

abstract：:Osteoblast-specific gene transcription requires interaction between bone cell-specific transcription factors and more widely expressed transcriptional regulators. This is particularly evident for the basic domain-leucine zipper factor activating transcription factor 4 (ATF4), whose activity can be enhanced or inhibite...

journal_title：Annals of the New York Academy of Sciences

authors： St-Arnaud R,Hekmatnejad B

更新日期：2011-11-01 00:00:00

abstract：:The mechanism of action of tocopherol transfer protein (TTP) and its role in the intracellular processing of vitamin E were investigated using confocal fluorescence microscopy. The results from this work suggest that TTP functions by transporting vitamin E from endocytic organelles to other locations in the cell. ...

journal_title：Annals of the New York Academy of Sciences

authors： Qian J,Wilson K,Nava P,Morley S,Atkinson J,Manor D

更新日期：2004-12-01 00:00:00

abstract：:Corn flour and maize meal fortification can benefit the consumer when the added nutrient contents are in amounts appropriate to address nutrient gaps. Legislative instruments (standards and regulations) are needed to provide guidance to the producers and food control authorities. We reviewed a number of national stand...

journal_title：Annals of the New York Academy of Sciences

authors： Makhumula P,Dary O,Guamuch M,Tom C,Afidra R,Rambeloson Z

更新日期：2014-04-01 00:00:00

abstract：:A sensitive, accurate, and simple method, called shifted termination assay (STA), was developed for detection of genetic mutations. The STA technology can be used to detect genetic mutations in polymerase chain reaction (PCR)-amplified samples of tissue, and plasma and serum that include circulating DNA containing poi...

journal_title：Annals of the New York Academy of Sciences

authors： Shackelford W,Deng S,Murayama K,Wang J

更新日期：2004-06-01 00:00:00

abstract：:We evaluated immune and endocrine status following antituberculosis treatment in HIV-negative patients with newly diagnosed tuberculosis (TB). Treatment led to a decrease in IL-6, IL-1β, and C-reactive protein levels. Cortisol levels decreased throughout the anti-TB treatment, particularly after 4 months, but changes ...

journal_title：Annals of the New York Academy of Sciences

authors： Bongiovanni B,Díaz A,D'Attilio L,Santucci N,Dídoli G,Lioi S,Nannini LJ,Gardeñez W,Bogue C,Besedovsky H,del Rey A,Bottasso O,Bay ML

更新日期：2012-07-01 00:00:00

abstract：:The distinction between episodic and semantic memory has become very popular since it was first proposed by Tulving in 1972. So far, very few neuropsychological, psychophysical, and imaging studies have related to the mnemonic aspects of music, notably on the long-term memory features, and practically nothing is known...

journal_title：Annals of the New York Academy of Sciences

authors： Platel H

更新日期：2005-12-01 00:00:00

abstract：:The trailblazing research on sleep mechanisms and petit mal epilepsy, conducted during the period from 1940 through 1970, illuminated the brain substrate for normal consciousness and attention, as well as their disorders. This research helped inform and structure our neuropsychologically based model of the "elements" ...

journal_title：Annals of the New York Academy of Sciences

authors： Mirsky AF,Duncan CC

更新日期：2001-06-01 00:00:00

abstract：:The Mediterranean diet is now recognized as being both limited in toxicity and abundant in nutrient and non-nutrient protective factors. A large body of basic, clinical and epidemiological studies have been developed in recent years to provide evidence of the benefits of the Mediterranean diet or its components on hea...

journal_title：Annals of the New York Academy of Sciences

authors： Covas MI,Marrugat J,Fitó M,Elosua R,de la Torre-Boronat C

更新日期：2002-05-01 00:00:00

abstract：:N. gonorrhoeae initiates infection by adhering to and invading columnar epithelial cells. Over time these activities often induce inflammation, with the influx of neutrophils and serum into the urethral lumen, cervical os, conjunctiva, and the like. At least some of these infected niches contain CMP-NANA (cytidine mon...

journal_title：Annals of the New York Academy of Sciences

authors： Rest RF,Liu J,Talukdar R,Frangipane JV,Simon D

更新日期：1994-08-15 00:00:00

abstract：:We test whether inhibition of inducible nitric oxide synthase (iNOS) can exert a cytoprotective effect on cerebral endothelial cells upon stimulation by pro-inflammatory cytokines. Mouse brain endothelial cells were stably transfected to express an antisense RNA against iNOS driven by an endothelium-specific von Wille...

journal_title：Annals of the New York Academy of Sciences

authors： Yang DI,Chen S,Ezekiel UR,Xu J,Wu Y,Hsu CY

更新日期：2005-05-01 00:00:00

abstract：:In the light of results of clinical trials with immunoisolated human parathyroid tissue Ba2+-alginate capsules were developed that meet the requirements for long-term immunoisolated transplantation of (allogeneic and xenogeneic) cells and tissue fragments. Biocompatibility of the capsules was achieved by subjecting hi...

journal_title：Annals of the New York Academy of Sciences

authors： Zimmermann U,Thürmer F,Jork A,Weber M,Mimietz S,Hillgärtner M,Brunnenmeier F,Zimmermann H,Westphal I,Fuhr G,Nöth U,Haase A,Steinert A,Hendrich C

更新日期：2001-11-01 00:00:00

abstract：:Full-grown amphibian oocytes, arrested in prophase I or meiosis, respond in vitro to progesterone and certain other steroids. They undergo an apparently normal sequence of nuclear maturation and cytoplasmic differentiation, which are necessary precedents for fertilization and embryogenesis. Individual oocytes or popul...

journal_title：Annals of the New York Academy of Sciences

authors： Schuetz AW

更新日期：1977-03-11 00:00:00

abstract：:Young songbirds memorize a tutor song and use the memory trace as a template to shape their own song by auditory feedback. Major issues in birdsong research include the neural sites and mechanisms for song memory and auditory feedback. The brain song control system contains neurons with both premotor and auditory func...

journal_title：Annals of the New York Academy of Sciences

authors： Konishi M

更新日期：2004-06-01 00:00:00

abstract：:The superior soft tissue contrast and multiplanar capability of magnetic resonance imaging has contributed to earlier diagnosis and implementation of effective treatment for a variety of arthropathies. Owing to overlapping clinical signs and symptoms, MRI plays a role in delineating the features and stages of these co...

journal_title：Annals of the New York Academy of Sciences

authors： Momeni M,Brindle K

更新日期：2009-02-01 00:00:00

abstract：:In this brief review, we introduce some major themes in the regulation of energy, lipid, and glucose metabolism by the central nervous system (CNS). Rather than comprehensively discussing the field, we instead will discuss some of the key findings made regarding the interaction of the hormones ghrelin and leptin with ...

journal_title：Annals of the New York Academy of Sciences

authors： Nogueiras R,Tschöp MH,Zigman JM

更新日期：2008-04-01 00:00:00

abstract：:We have used site-directed mutagenesis to investigate the contributions of widely distributed residues in the thymosin beta-4 (Tbeta4) sequence to the formation and stability of the actin-Tbeta4 complex. Equilibrium and kinetic studies of actin binding were performed by monitoring the change in fluorescence of an N-io...

journal_title：Annals of the New York Academy of Sciences

authors： Au JK,De La Cruz EM,Safer D

更新日期：2007-09-01 00:00:00

abstract：:The emission factors for indoor straw combustion are a major data gap for estimating the polycyclic aromatic hydrocarbon (PAH) emissions in China. The emission factors for open-fire straw burning were borrowed from our previous study and a rough estimate was developed. As one of the most important emission sources in ...

journal_title：Annals of the New York Academy of Sciences

authors： Zhang Y,Dou H,Chang B,Wei Z,Qiu W,Liu S,Liu W,Tao S

更新日期：2008-10-01 00:00:00

abstract：:Severely inflamed colonic sections of IL-2 (-/-) mice showed up to 19-fold increased iNOS mRNA levels. The level of iNOS protein expression corresponded to the increased iNOS mRNA levels as detected by means of Western blot analysis. There was a clear, positive relationship between the level of iNOS expression and the...

journal_title：Annals of the New York Academy of Sciences

authors： Harren M,Schönfelder G,Paul M,Horak I,Riecken EO,Wiedenmann B,John M

更新日期：1998-11-17 00:00:00

abstract：:The measurement of autoantibodies specific for double-stranded DNA (anti-dsDNA) is a useful tool for the diagnosis and the prognosis of systemic lupus erythematosus (SLE). A new quantitative enzyme-linked immunosorbent assay (ELISA), ORG anti-dsDNA, is recently available for the determination of anti-dsDNA antibodies....

journal_title：Annals of the New York Academy of Sciences

authors： Bardin N,Ragot C,Sanmarco M

更新日期：2007-08-01 00:00:00

abstract：:Mitochondrial dysfunction, due to either environmental or genetic factors, can result in excessive production of reactive oxygen species, triggering the apoptotic death of dopaminergic cells in Parkinson's disease. Mitochondrial free radical production is promoted by the inhibition of electron transport at any point d...

journal_title：Annals of the New York Academy of Sciences

authors： Fiskum G,Starkov A,Polster BM,Chinopoulos C

更新日期：2003-06-01 00:00:00

abstract：:Latent chronic ascorbic acid deficiency provokes in guinea pigs a metabolic disorder in the liver, causing an impaired cholesterol transformation to its principal catabolic product, bile acids. This metabolic disorder induces hypercholesterolemia and accumulation of cholesterol in the liver and slows the release of ch...

journal_title：Annals of the New York Academy of Sciences

authors： Ginter E

更新日期：1975-09-30 00:00:00

abstract：:In this article, we have presented an overview of fundamental issues involved in mediphotonic imaging, and reviewed some of the emerging techniques for early-light transillumination imaging of body organs. The results on human breast tissues presented here, together with the data accumulated and advances made by resea...

journal_title：Annals of the New York Academy of Sciences

authors： Alfano RR,Demos SG,Gayen SK

更新日期：1997-05-30 00:00:00

abstract：:Insulin-like factor 3 (INSL3), previously known as the relaxin-like factor (RLF), is a major peptide hormone secreted from the testicular Leydig cells of adult men and circulating in the blood at a concentration of approximately 1 ng/mL. Women also produce INSL3 in the theca interna cells of ovarian follicles, but cir...

journal_title：Annals of the New York Academy of Sciences

authors： Ivell R,Hartung S,Anand-Ivell R

更新日期：2005-05-01 00:00:00

abstract：:Converging lines of evidence indicate that withdrawal from prolonged exposure to stimulants and alcohol results in synaptic deficits of both dopamine (DA) and serotonin (5-HT). According to the dual deficit model proposed by the authors, DA dysfunction during cocaine or alcohol withdrawal underlies anhedonia and psych...

journal_title：Annals of the New York Academy of Sciences

authors： Rothman RB,Partilla JS,Dersch CM,Carroll FI,Rice KC,Baumann MH

更新日期：2000-09-01 00:00:00

abstract：:Over most of the past century, it was thought that the adult brain was completely incapable of generating new neurons. However, in the last decade, the development of new techniques has resulted in an explosion of new research showing that (i) neurogenesis, the birth of new neurons, is not restricted to embryonic deve...

journal_title：Annals of the New York Academy of Sciences

authors： Arlotta P,Magavi SS,Macklis JD

更新日期：2003-06-01 00:00:00

abstract：:A triple genetic association between serum IgE levels, mast cell numbers, and susceptibility to oral tolerance was observed in mice genetically selected to extreme phenotypes of oral tolerance (susceptibility and resistance), suggesting a coadaptation of genes controlling these traits. ...

journal_title：Annals of the New York Academy of Sciences

authors： da Silva AC,Silva MF,Bianchi C,Ribeiro RC,Nóbrega A,Sant'anna O

更新日期：2004-12-01 00:00:00