Abstract:
:Availability of reducing factors (e.g., NADH and NADPH) plays an important role in improving the efficacy of products conversion in cofactor-dependent production systems. In this study, nicotinic acid (NA), the precursor of NADH and NADPH, was supplemented to the growth medium of a wild-type Clostridium sp. strain BOH3. Results showed that the addition of precursor NA to the medium led to a significant increase in the levels of NADH and NADPH. Meanwhile, a maximal cell growth rate and butanol generation rate were reached by applying a two-stage pH-shift strategy, achieving 18.7g/L butanol with a yield of 24.6% and a productivity of 0.26g/Lh. The metabolic patterns were shifted towards more reduced metabolites as reflected by higher butanol-to-acetone ratio (11%) and butanol-to-acid ratio (292%). Redistributing metabolic flux to butanol via manipulations of reducing cofactor and pH shift could become an alternative tool to realize metabolic engineering goals.
journal_name
Bioresour Technoljournal_title
Bioresource technologyauthors
Li T,Yan Y,He Jdoi
10.1016/j.biortech.2013.12.089subject
Has Abstractpub_date
2014-03-01 00:00:00pages
220-8eissn
0960-8524issn
1873-2976pii
S0960-8524(13)01929-9journal_volume
155pub_type
杂志文章abstract::Biohydrogen from microalgae has attracted extensive attention owing to its promising features of abundance, renewable and self sustainability. Unlike other well-established biofuels like biodiesel and bioethanol, biohydrogen from microalgae is still in the preliminary stage of development. Criticisms in microalgal bio...
journal_title:Bioresource technology
pub_type: 杂志文章,评审
doi:10.1016/j.biortech.2019.121747
更新日期:2019-10-01 00:00:00
abstract::The effect of two additives on anaerobic monodigestion of pig slaughterhouse waste was studied in three laboratory scale continuously stirred tank reactors (CSTRs) operated for 242-284 days at 35°C. A higher organic loading rate (OLR), namely 2.25 kg volatile solids (VS)/m(3)d with a hydraulic retention time (HRT) of ...
journal_title:Bioresource technology
pub_type: 杂志文章
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journal_title:Bioresource technology
pub_type: 杂志文章,评审
doi:10.1016/j.biortech.2018.04.030
更新日期:2018-10-01 00:00:00
abstract::The landfill gas (LFG) model is a tool for measuring methane (CH4) generation rates and total CH4 emissions from a particular landfill. These models also have various applications including the sizing of the LFG collection system, evaluating the benefits of gas recovery projects, and measuring and controlling gaseous ...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2016.06.050
更新日期:2016-09-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2010.11.036
更新日期:2011-02-01 00:00:00
abstract::Meat and bone meal (MBM), a product of the rendering industry, is a potential feedstock for numerous bio-based applications. Design of processing equipment for MBM is difficult due to MBM's bulk behaviors; it flows less easily than many other granular materials, and it tends to foul the surfaces of processing equipmen...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2006.09.053
更新日期:2007-11-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2016.07.008
更新日期:2016-10-01 00:00:00
abstract::The objective of this study was to evaluate the adsorption of tetracycline (TC) on the Pinus taeda-derived activated biochar (BC). After NaOH activation, the well-developed porous surface structure was observed with a significantly increase in surface area (959.9 m2/g). The kinetic and isotherm studies indicated that ...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2018.03.013
更新日期:2018-07-01 00:00:00
abstract::A bacterium with an exceptional ability to hydrolyse fenamiphos and its toxic oxidation products fenamiphos sulfoxide and fenamiphos sulfone, all possessing POC bond was isolated from soil. Based on 16S rRNA gene determination, this bacterium was putatively identified as Microbacterium esteraromaticum. The phenols (fe...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2008.12.043
更新日期:2009-05-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2020.124199
更新日期:2021-01-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2017.09.100
更新日期:2018-01-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2020.123079
更新日期:2020-02-26 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2011.12.035
更新日期:2012-03-01 00:00:00
abstract::External stress factors in the form of ionic species or temperature increases have been shown to produce a stress response leading to enhanced PHA production. The effect of five different NaCl concentrations, namely 3.5, 6.5, 9, 12 and 15 g/l NaCl on PHA productivity using Cupriavidus necator has been investigated alo...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2014.04.068
更新日期:2014-07-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2020.122866
更新日期:2020-04-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2017.12.034
更新日期:2018-03-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2018.08.048
更新日期:2018-11-01 00:00:00
abstract::tert-Butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate ((3R,5S)-CDHH) is the key intermediate for synthesis of atorvastatin and rosuvastatin. Carbonyl reductase exhibits excellent activity toward tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate ((S)-CHOH) to synthesize (3R,5S)-CDHH. In this study, a whole cell biosynthesi...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2017.09.204
更新日期:2018-02-01 00:00:00
abstract::The community dynamics of attached and free cells of Acidithiobacillus sp. were investigated and compared during chalcopyrite bioleaching process. In the mixed strains system, Acidithiobacillus ferrooxidans was the dominant species at the early stage while Acidithiobacillus thiooxidans owned competitive advantage from...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2013.12.036
更新日期:2014-02-01 00:00:00
abstract::Metal concentrations were measured in plants growing on heavily contaminated tailings from a mine active since about 1800 in San Luis Potosí (Mexico). Viguiera dentata (Cav.) Spreng., Parthenium bipinnatifidum (Ort.) Rollins, Flaveria angustifolia (Cav.) Pers., F. trinervia (Spreng.) C. Mohr. and Sporobolusindicus (L....
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2010.01.013
更新日期:2010-06-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2014.02.045
更新日期:2014-08-01 00:00:00
abstract::Interspecies electron transfer between bacteria and archaea plays a vital role in enhancing energy efficiency of anaerobic digestion (AD). Conductive carbon materials (i.e. graphene nanomaterial and activated charcoal) were assessed to enhance AD of ethanol (a key intermediate product after acidogenesis of algae). The...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2017.05.017
更新日期:2017-09-01 00:00:00
abstract::Modification of the physical properties of old corrugated container (OCC) pulp with laccase or a laccase-mediator (ABTS, HBT, VA) system was investigated under select enzymatic concentrations and reaction times. The optimal conditions for laccase treatment shown to be using a laccase dose of 160U/g o.d. pulp, a treatm...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2011.12.120
更新日期:2012-04-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2008.12.036
更新日期:2009-06-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2010.04.083
更新日期:2011-01-01 00:00:00
abstract::The depolymerization of renewable lignin for phenolic monomer, a versatile biochemical and precursor for biofuel, has attracted increasing attention. Here, an efficient base-catalyzed depolymerization process for this natural aromatic polymer is presented with cheap industrial solid alkali MgO and biomass-derived solv...
journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2013.12.020
更新日期:2014-02-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2016.03.016
更新日期:2016-06-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2010.06.041
更新日期:2010-11-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2018.02.075
更新日期:2018-06-01 00:00:00
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journal_title:Bioresource technology
pub_type: 杂志文章
doi:10.1016/j.biortech.2020.124541
更新日期:2020-12-14 00:00:00