A single report of hemiplegic arm stretching related to yawning: further investigation using apomorphine administration.

abstract：OBJECTIVES:To determine the impact of disease progression on health-related quality of life in amyotrophic lateral sclerosis (ALS). METHODS:A total of 161 patients with ALS were enrolled. Assessments included the revised ALS Functional Rating Scale and the ALS Assessment Questionnaire (ALSAQ-40). Data analysis compris...

journal_title：Journal of the neurological sciences

authors： Prell T,Gaur N,Stubendorff B,Rödiger A,Witte OW,Grosskreutz J

更新日期：2019-02-15 00:00:00

abstract：:Fifteen Moroccan families with a phenotype resembling Friedreich Ataxia (FA) were studied. Seven families (13 patients) had the 744 del A mutation in the alpha-tocopherol transfer protein (alpha-TTP) gene, characteristic of ataxia with vitamin E deficiency (AVED). The other eight families (16 patients) had GAA expansi...

journal_title：Journal of the neurological sciences

authors： Benomar A,Yahyaoui M,Meggouh F,Bouhouche A,Boutchich M,Bouslam N,Zaim A,Schmitt M,Belaidi H,Ouazzani R,Chkili T,Koenig M

更新日期：2002-06-15 00:00:00

abstract：:In view of recent reports on lower brainstem dysfunction in Huntington's chorea, we studied respiration during sleep in 12 patients with Huntington's chorea (HC) and in controls. There were no statistically significant differences between patients and controls with respect to apnea periods, respiratory frequency and t...

journal_title：Journal of the neurological sciences

authors： Bollen EL,Den Heijer JC,Ponsioen C,Kramer C,Van der Velde EA,Van Dijk JG,Roos RA,Kamphuisen HA,Buruma OJ

更新日期：1988-03-01 00:00:00

abstract：:This paper describes a histochemical and histographic analysis of the masticatory muscles obtained from 78 early autopsy samples from subjects from 4 days to 87 years old. Five groups of muscles have been stuied: the temporalis, the medial and lateral pterygoid, the superficial bundle of the masseter and the mylohyoid...

journal_title：Journal of the neurological sciences

authors： Vignon C,Pellissier JF,Serratrice G

更新日期：1980-03-01 00:00:00

abstract：:In addition to the G2019S mutation in the leucine-rich repeat kinase 2 gene (LRRK2), which is particularly frequent in patients of Ashkenazi Jewish and Northern African origin, three amino acid substitutions (R1441C, R1441G, and R1441H), all at the same residue (R1441), have been identified as important genetic causes...

journal_title：Journal of the neurological sciences

authors： Deng H,Le W,Guo Y,Hunter CB,Xie W,Huang M,Jankovic J

更新日期：2006-12-21 00:00:00

abstract：BACKGROUND:A specific non-motor impairment in Parkinson's disease (PD) concerns difficulties to accurately identify facial emotions. Findings are numerous but very inconsistent, ranging from general discrimination deficits to problems for specific emotions up to no impairment at all. By contrast, only a few studies exi...

journal_title：Journal of the neurological sciences

authors： Ille R,Wabnegger A,Schwingenschuh P,Katschnig-Winter P,Kögl-Wallner M,Wenzel K,Schienle A

更新日期：2016-02-15 00:00:00

abstract：:The phase of rapid reduction of isometric strength in single muscle groups was identified and its slope was calculated in patients studied with the TQNE method. This parameter was studied in the extremities and in respiration in 4 ALS patients and 4 PMA (progressive spinal muscle atrophy) patients. The slopes of the s...

journal_title：Journal of the neurological sciences

authors： Conradi S,Ronnevi LO

更新日期：1996-08-01 00:00:00

abstract：:To assess the role of CSF oligoclonal bands (OB) in determining the clinical outcome in patients with relapsing-remitting multiple sclerosis (RRMS) treated with IFN-beta, we carried out a retrospective, multicentre, observational study recruiting 209 RRMS patients from six MS centres from northern, central and souther...

journal_title：Journal of the neurological sciences

authors： Annunziata P,Giorgio A,De Santi L,Zipoli V,Portaccio E,Amato MP,Clerici R,Scarpini E,Moscato G,Iudice A,Vacca G,Orefice G,Morra VB,Maimone D

更新日期：2006-05-15 00:00:00

abstract：:The Alzheimer's disease (AD) related amyloid precursor protein (APP) is stored, cleaved and released similarly from neurons and from platelets. We have reported that the proportion of 120-130 to 110 kDa carboxyl-cleaved APP present in the platelets of AD patients is significantly lower than that of platelets of age-ma...

journal_title：Journal of the neurological sciences

authors： Baskin F,Rosenberg RN,Iyer L,Schellenberg GD,Hynan L,Nee LE

更新日期：2001-01-15 00:00:00

abstract：:The pathophysiological mechanism of the pain in ALS is still unclear. The aim of the study was to evaluate the laser evoked potentials (LEPs) in ALS patients in relation to their clinical features. Twenty-four ALS patients were selected. Pain features were assessed and their intensity was measured by a 0-10 VAS. LEPs ...

journal_title：Journal of the neurological sciences

authors： Simone IL,Tortelli R,Samarelli V,D'Errico E,Sardaro M,Difruscolo O,Calabrese R,Francesco Vde V,Livrea P,de Tommaso M

更新日期：2010-01-15 00:00:00

abstract：:Hypereosinophilic syndrome represents a rare cause for cerebral infarctions and inflammatory neurological disorders. Various possible pathogenic mechanisms for cerebral infarctions have already been discussed. Complex mechanisms including a local hypercoagulability by eosinophilic granules as well as a direct damage t...

journal_title：Journal of the neurological sciences

authors： Bolz J,Meves SH,Kara K,Reinacher-Schick A,Gold R,Krogias C

更新日期：2015-09-15 00:00:00

abstract：:A boy, who had shown muscle weakness and hypotonia from early childhood and fiber type disproportion (FTD) with no dystrophic changes on muscle biopsy, was initially diagnosed as having congenital fiber type disproportion (CFTD). Subsequently, he developed cardiac conduction blocks. We reconsidered the diagnosis as po...

journal_title：Journal of the neurological sciences

authors： Kajino S,Ishihara K,Goto K,Ishigaki K,Noguchi S,Nonaka I,Osawa M,Nishino I,Hayashi YK

更新日期：2014-05-15 00:00:00

abstract：:Clinical manifestations, outcomes, prognostic indicators, and clinico-epidemiological subgroups were described based on the information of 71 patients with Guillain-Barré syndrome (GBS), who were identified from a prospective survey in Harbin, China during a 1-year period from 1 October 1997 to 30 September 1998. GBS ...

journal_title：Journal of the neurological sciences

authors： Cheng Q,Wang DS,Jiang GX,Han H,Zhang Y,Wang WZ,Fredrikson S

更新日期：2003-11-15 00:00:00

abstract：:Adult onset cerebral X-ALD (AOCALD) is a rare disease, but should be considered an important differential diagnosis in adults presenting with leukencephalopathy. We here report the case of a 40-year-old man with a history of progressive cognitive decline who presented with a first-time seizure. Initial workup included...

journal_title：Journal of the neurological sciences

authors： Dohle CI,Bannykh SI,Hisama FM,Baehring JM

更新日期：2009-10-15 00:00:00

abstract：PURPOSE:To describe additional cases of subacute encephalopathy with seizures in alcoholics (SESA) syndrome, and to question the clinical and radiological course. METHODS:We retrospectively analyzed the clinical characteristics, electroencephalography (EEG), MRI studies at the admission and over the following 6 months...

journal_title：Journal of the neurological sciences

authors： Duwicquet C,Biberon J,Corcia P,De Toffol B,Limousin N

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:MS relapses are unpredictable and can be concerning to patients and their caregivers. OBJECTIVE:To assess the direct and indirect cost burden associated with relapses of different severities in MS patients and with MS relapse frequency on spouse caregivers. METHODS:Using a U.S. insurance claims and employe...

journal_title：Journal of the neurological sciences

authors： Parisé H,Laliberté F,Lefebvre P,Duh MS,Kim E,Agashivala N,Abouzaid S,Weinstock-Guttman B

更新日期：2013-07-15 00:00:00

abstract：:Deficient activity of human lysosomal hydrolase, acid sphingomyelinase (ASM), results in the neuronopathic (type A) and non-neuronopathic (type B) forms of Niemann-Pick disease (NPD). A deficiency of ASM is known to deprive lymphoblasts of their response to apoptotic induction by X-ray irradiation. To elucidate the ge...

journal_title：Journal of the neurological sciences

authors： Mikami T,Takahashi T,Ishida A,Minamiya Y,Ida H,Takada G

更新日期：2002-07-15 00:00:00

abstract：:The aim of the present study was to determine whether a cognitive decline, related to multiple sclerosis (MS), also involves deficits in semantic memory. Semantic memory function was evaluated by studying the conscious understanding of conceptual meanings. A group of MS patients with cognitive decline was presented wi...

journal_title：Journal of the neurological sciences

authors： Laatu S,Hämäläinen P,Revonsuo A,Portin R,Ruutiainen J

更新日期：1999-01-15 00:00:00

abstract：:Hypnic headache (HH) is a rare benign disorder described initially by Raskin in 1988. It is characterized by recurrent nocturnal episodes of headache that periodically awaken the sleeping patient and usually occur in the elderly. This review aimed to describe the clinical features of the HH cases published in the lite...

journal_title：Journal of the neurological sciences

authors： Silva-Néto RP,Santos PEMS,Peres MFP

更新日期：2019-06-15 00:00:00

abstract：:The analysis of the firing intervals of motor units has been suggested as a diagnostic tool in patients with neuromuscular disorders. Part of the increase in number of turns seen in patients with myopathy could be secondary to the decrease in motor unit firing intervals at threshold force of the motor units, as noted ...

journal_title：Journal of the neurological sciences

authors： Fuglsang-Frederiksen A,Smith T,Høgenhaven H

更新日期：1987-03-01 00:00:00

abstract：:The recent history of clinical trials in ALS is marked by a great diversity in trial design. This has limited the comparability of the trial results, and has resulted in intense discussions about which parameters should or should not be evaluated when testing a new drug for ALS. This article discusses, without any cla...

journal_title：Journal of the neurological sciences

authors： Borasio GD

更新日期：1997-10-01 00:00:00

abstract：:A 52-year-old Japanese woman complaining of horizontal double vision for 10 days was admitted to our hospital. Neurological examination revealed left abducent nerve palsy and muscle swelling in her thighs. Brain MRI showed obstruction in the spinal fluid space of the left Dorello's canal, which transmits a portion of ...

journal_title：Journal of the neurological sciences

authors： Shioya A,Takuma H,Shiigai M,Ishii A,Tamaoka A

更新日期：2014-08-15 00:00:00

abstract：BACKGROUND:To evaluate the presence of ischemic and hemorrhagic lesions in brain MRI of patients with Fabry disease (FD). METHODS:Brain MRI studies in 46 consecutive patients were evaluated using classic sequences as well as GRE-weighted images, for ischemic lesions and chronic microbleed detection. Of the 36 adult pa...

journal_title：Journal of the neurological sciences

authors： Reisin RC,Romero C,Marchesoni C,Nápoli G,Kisinovsky I,Cáceres G,Sevlever G

更新日期：2011-06-15 00:00:00

abstract：:Autoantibodies against astrocyte water channel aquaporin-4 (AQP4) are highly specific for neuromyelitis optica (NMO). However, the molecular mechanism of NMO still remains unclear. The purpose of this study was to identify the possible humoral mechanisms responsible for the occurrence of astrocytic damage. Human prima...

journal_title：Journal of the neurological sciences

authors： Haruki H,Sano Y,Shimizu F,Omoto M,Tasaki A,Oishi M,Koga M,Saito K,Takahashi T,Nakada T,Kanda T

更新日期：2013-08-15 00:00:00

abstract：:Superficial siderosis (SS) of the central nervous system is a rare disorder caused by chronic or recurrent hemorrhages into the subarachnoid space with hemosiderin and ferritin deposition, which leads to neuronal damage. The source of bleeding remains unknown in 50% of cases. Recently, attention has been focused on fl...

journal_title：Journal of the neurological sciences

authors： Boncoraglio GB,Ballabio E,Erbetta A,Prada F,Savoiardo M,Parati EA

更新日期：2012-01-15 00:00:00

abstract：:We studied a 21-year-old patient with clinical, biochemical and histochemical evidence of myophosphorylase deficiency and unusual repetitive episodes of pigmenturia. His muscle biopsy also revealed morphological signs of mitochondrial proliferation and a defect of complex I of the respiratory chain. His mother had exe...

journal_title：Journal of the neurological sciences

authors： Rubio JC,Martín MA,Bautista J,Campos Y,Segura D,Cabello A,Chinchón I,Arenas J

更新日期：1998-12-11 00:00:00

abstract：OBJECTIVE:To determine the influence of different factors on test-retest reliability of frequently used transcranial magnetic stimulation (TMS) parameters while controlling for potential confounders in healthy subjects. METHODS:TMS was applied in 93 healthy volunteers (61% male) twice (mean retest interval of 34.0 ± 2...

journal_title：Journal of the neurological sciences

authors： Hermsen AM,Haag A,Duddek C,Balkenhol K,Bugiel H,Bauer S,Mylius V,Menzler K,Rosenow F

更新日期：2016-03-15 00:00:00

abstract：:Memantine, a clinically employed drug with N-methyl-D-aspartate (NMDA) receptor antagonistic effects, dose-dependently ameliorates neurological deficits in Lewis rat experimental autoimmune encephalomyelitis (EAE). Interestingly, this therapeutic effect was not due to dampened CNS inflammation, as assessed by immunohi...

journal_title：Journal of the neurological sciences

authors： Wallström E,Diener P,Ljungdahl A,Khademi M,Nilsson CG,Olsson T

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of balance training on Force Platform with Visual Feedback technique (FPVF) in improving balance and functional outcome in chronic stroke survivors. DESIGN:Prospective, repeated measure study. SETTINGS:Neurological rehabilitation department of a tertiary research center. PARTICIPANTS:F...

journal_title：Journal of the neurological sciences

authors： Srivastava A,Taly AB,Gupta A,Kumar S,Murali T

更新日期：2009-12-15 00:00:00

abstract：:We prospectively examined the effect of arundic acid (AA; ONO-2506) on S-100beta, an astrocyte-derived protein, in a phase I acute stroke study. Subjects with acute ischemic stroke were randomized to daily infusion of AA or placebo for 7 days. Serum S-100beta levels were assayed pre-infusion on Days 1-7 and post-infus...

journal_title：Journal of the neurological sciences

authors： Pettigrew LC,Kasner SE,Gorman M,Atkinson RP,Funakoshi Y,Ishibashi H,Arundic Acid (ONO-2506) Stroke Study Group.

更新日期：2006-12-21 00:00:00