Abstract:
:Life history theory predicts a trade-off between immunostimulation and growth. Using a cross-sectional study design, this study aims to test the hypothesis that C-reactive protein (CRP) is negatively associated with height-for-age z-scores (HAZ scores) and BMI-for-age z-scores (BAZ scores) among 6- to 19-year olds (N = 426) residing in five Nepalese communities. Dried blood spot (DBS) samples were collected and assayed for CRP using an in-house enzyme immunoassay (EIA). Sex- and age-group-specific CRP quartiles were used to examine its association with growth in linear mixed-effects (LME) models. A significant difference was found in the proportion of elevated CRP (>2 mg/L, equivalent to ∼3.2 mg/L serum CRP) between 13- and 19-year-old boys (12%) and girls (4%). Concentrations of CRP were positively associated with HAZ score among adolescent (13-19 years) boys, which may indicate that individuals with greater energy resources have better growth and a better response to infections, thus eliminating the expected trade-off between body maintenance (immunostimulation) and growth. Adolescent boys with low BAZ and HAZ scores had low CRP values, suggesting that those who do not have enough energy for growth cannot increase their CRP level even when infected with pathogens. Among adolescent girls a positive association was observed between CRP and BAZ scores suggesting the possible effects of chronic low-grade inflammation due to body fat rather than infection. The association between CRP and growth was less evident among children (6-12 years) compared with adolescents, indicating that the elevated energy requirement needed for the adolescent growth spurt and puberty may play some role.
journal_name
Am J Phys Anthropoljournal_title
American journal of physical anthropologyauthors
Konishi S,Parajuli RP,Takane E,Maharjan M,Tachibana K,Jiang HW,Pahari K,Inoue Y,Umezaki M,Watanabe Cdoi
10.1002/ajpa.22470subject
Has Abstractpub_date
2014-05-01 00:00:00pages
42-51issue
1eissn
0002-9483issn
1096-8644journal_volume
154pub_type
杂志文章abstract::The dental casts taken of Aboriginal people resident at Yuendumu, Central Australia, between 1950-1970 preserve a unique historical record of defects of the dental enamel (DDEs) among people born from 1890-1960 (n = 377). These data are used, in comparison with precontact data, to trace the chronological changes in ch...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.20054
更新日期:2005-03-01 00:00:00
abstract::Haplogroup R1a1-M198 is a major clade of Y chromosomal haplogroups which is distributed all across Eurasia. To this date, many efforts have been made to identify large SNP-based subgroups and migration patterns of this haplogroup. The origin and spread of R1a1 chromosomes in Eurasia has, however, remained unknown due ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22167
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVES:Many studies on subadult sex estimation focus on elements that express sexually dimorphic features in adults. In contrast, diaphyseal dimensions have been shown to display sex-specific differences prior to adolescence. The current study evaluates the use of diaphyseal dimensions in subadult sex estimation. ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.23185
更新日期:2017-05-01 00:00:00
abstract::New data were obtained on mitochondrial DNA (mtDNA) from Guahibo from Venezuela, a group so far not studied using molecular data. A population sample (n = 59) was analyzed for mtDNA variation in two control-region hypervariable segments (HV1 and HV2) by sequencing. The presence or absence of a 9-bp polymorphism in the...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.20070
更新日期:2005-07-01 00:00:00
abstract::Pliopithecid remains from the Spanish locality of Torrent de Febulines (Late Vallesian, MN 10), consisting of right and left mandibular fragments with partial tooth rows and an isolated P(3) probably belonging to the same individual, are described and assigned to Egarapithecus narcisoi gen. et sp. nov. (Pliopithecidae...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1043
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVES:The arrival of the Huns into Europe in the fourth century AD increased the occurrence of intentional cranial modification among European nomads. It has been postulated that the Huns used a two-bandage cranial binding technique to differentiate themselves from surrounding nomadic groups, including those from ...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.23412
更新日期:2018-05-01 00:00:00
abstract::Sexual dimorphism in primate species expresses the effects of phylogeny, life history, behavior, and ontogeny. The causes and implications of sexual dimorphism have been studied in several different primates using a variety of morphological databases such as body weight, canine length, and coat color and ornamentation...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-8644(199811)107:3<243::AID-AJPA
更新日期:1998-11-01 00:00:00
abstract::An investigation of body height and cephalic measurements was performed among five groups of first-year medical students of the University of Rijeka School of Medicine (Rijeka, Croatia). Body height and different cephalic measurements showed normal distribution, both in male and female students. Differences between me...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.10306
更新日期:2004-01-01 00:00:00
abstract::Members of the Cercocebus-Mandrillus clade are united by several morphological features, including expanded premolars which are argued to be associated with a preponderance of hard objects in the diet. We test the association between premolar expansion and hard object feeding by examining how different dental regions ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.21402
更新日期:2011-01-01 00:00:00
abstract::It is unclear whether earlier age at menarche is associated with higher body mass index (BMI) because they share a common genetic underpinning. We investigated the impact of single nucleotide polymorphisms (SNPs) influencing menarche timing on peripubertal BMI. For 556 Fels Longitudinal Study children (277 boys/279 gi...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.22121
更新日期:2013-01-01 00:00:00
abstract::Body proportions and tissue composition (e.g., relative contributions of muscle, skin, bone, and adipose to total body mass) were determined through dissection of four adult captive lowland gorillas. The relative contribution of bone varies little among the four animals (10.2-13.4%) despite considerable range in body ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/1096-8644(200009)113:1<61::AID-AJPA6>3.0.C
更新日期:2000-09-01 00:00:00
abstract::Population genetic studies in Saudi Arabia are performed for EsD, GPT, AcP, ADA, AK, 6-PGD, PGM, C3, Tf, Hp, Gc, Pi, Bf, Hb, ABO-blood groups and Rh-factor, level of the third component of complement and immunoglobulins. The data are compared with reported frequencies in European and African populations. ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330500217
更新日期:1979-02-01 00:00:00
abstract::Although it is commonly stated that the ischia of the late Pliocence-early Pleistocene hominid fossils are long and ape-like, new interpretations show this view to be falacious. An important new theory proposed by Robinson concludes that the gracile form of early hominid was an efficient biped, but the robust form was...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.1330430107
更新日期:1975-07-01 00:00:00
abstract::Previous research has revealed extensive genetic variation among villages on Bougainville, in the Solomon Islands. Using previously published gene frequency data for seven loci, the role of isolation by distance in structuring genetic variation on Bougainville was reanalyzed. Newer methods of kinship estimation show t...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330660309
更新日期:1985-03-01 00:00:00
abstract::Scratches found on the Engis 2 cranium have been described as perimortem and interpreted as intentional scalping marks by Russell and LeMort (Am. J. Phys. Anthropol. 69:317-323, 1986). These marks are described and compared to damage on other fossil hominids. The Engis marks have been misinterpreted. These marks are s...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330780305
更新日期:1989-03-01 00:00:00
abstract::The relationship between diarrheal diseases and growth increments in total body length and weight was investigated in 716 rural Ladino Gautemalan children. Data on diarrheal diseases were provided by the mothers through retrospective surveys carried out at 14-day intervals. Increments in length and weight, semestral f...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330430307
更新日期:1975-11-01 00:00:00
abstract::Previous works on the inheritance of dental traits have traditionally followed Fisher's model for family data under the assumption that phenotypic similarity between relatives is due solely to genetic factors. This study uses recent causal models that incorporate the contribution of nonrandom environmental sources of ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330610302
更新日期:1983-07-01 00:00:00
abstract::Hominid fossil teeth are analyzed in terms of size and shape and contrasted with teeth from a modern population to determine boundaries that can be placed on a reconstruction of the hominid phylogeny. Teeth alone are considered as they are the only material preserved in large enough quantities to measure population va...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330420115
更新日期:1975-01-01 00:00:00
abstract::A previous study of passive joint mobility in patas monkeys (Erythrocebus patas) showed that laboratory-caged animals had significantly greater mobility in most joints than age/sex matched free-ranging monkeys. Passive joint mobility on 27 of the same animals was measured 6 months after the caged animals were released...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330670102
更新日期:1985-05-01 00:00:00
abstract::New insights may be gleaned by taking an ontogenetic approach to investigations of adult dimorphism. Previous work in this area relied on traditional, caliper-based, morphometric methods, and produced conflicting results. This study uses a three-dimensional (3-D) approach for both local and global form comparisons of ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.10178
更新日期:2003-05-01 00:00:00
abstract::Recent research shows that a bacterial life form, Erysipelothrix insidiosa, can produce rheumatoid arthritis in deer, swine, and dogs, and that a number of animals, including man, birds, and fish, may be infected by the organism. Examination of the archaeological record suggests that both cultural and biological varia...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.1330430109
更新日期:1975-07-01 00:00:00
abstract::A number of researchers have hypothesized that the biomechanical forces associated with cultural cranial deformation can influence the formation of sutural ossicles. However, it is still difficult to make definitive conclusions about this relationship because the effects appear to be quite weak, and contradictory resu...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.21005
更新日期:2009-08-01 00:00:00
abstract::Research to understand human genomic variation and its implications in health has great potential to contribute in the reduction of health disparities. Biological anthropology can play important roles in genomics and health disparities research using a biocultural approach. This paper argues that racial/ethnic categor...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.24144
更新日期:2020-09-16 00:00:00
abstract::Two threshold models, a single locus model, and two combined models are fitted to data on familial incidence of bipolar affective disorder in 194 nuclear families ascertained through a bipolar proband. The relative fit of alternative transmission models is tested by a likelihood ratio chi-square with the degrees of fr...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330620108
更新日期:1983-09-01 00:00:00
abstract::Bilateral tooth measurements in twins are partitioned into three orthogonal contrasts, each associated with one degree of freedom, to estimate three parameters: discordance, asymmetry, and mirror imagery. The probability levels of the within-pair variance ratios were used to test for significance of these estimates. T...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330440303
更新日期:1976-05-01 00:00:00
abstract::Genealogical and gene marker data from the closely related species Macaca mulatta and Macaca fascicularis have been used to search for linkage between genes coding for the blood proteins albumin, carbonic anhydrase 1 and 2, diaphorase 1 and 2, group-specific component, glucose phosphate isomerase, hemoglobin alpha cha...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330680302
更新日期:1985-11-01 00:00:00
abstract::Height and weight were compared across five birth decades (1850-1899) among 1,121 Harvard athletes who were lettermen in various sports. There were considerable differences in the magnitude of the secular trend among the sport categories (crew, baseball, football, track, ice hockey, and two or more sports). Comparing ...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330420318
更新日期:1975-05-01 00:00:00
abstract::The approximal surfaces of premolars and molars of 376 adult British-Romano skulls were examined for wear facets. The type of wear was designated as convex, concave, sigmoid, or flat, and the degree was categorised on a three-point scale. Concave wear facets were more frequently seen in the older age groups, but the t...
journal_title:American journal of physical anthropology
pub_type: 历史文章,杂志文章
doi:10.1002/ajpa.1330730309
更新日期:1987-07-01 00:00:00
abstract::In investigating the dermatoglyphics of hyperactive subjects, it was proposed that if similar hyperactives were sampled and significant differences were found from suitable controls, a genetic effect could be responsible. From two clinical populations, we ascertained 26 subjects in 24 sibships comprising the hyperacti...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330590303
更新日期:1982-11-01 00:00:00
abstract::The bone mineral content (BMC), bone width, and cross-sectional moment of inertia (CSMI) of 141 Alaskan Eskimo tibias were measured using photon absorptiometry. The effects of age and sex on the bones' structural properties were studied. It was found that in women, BMC decreased by 50% between the third and sixth deca...
journal_title:American journal of physical anthropology
pub_type: 杂志文章
doi:10.1002/ajpa.1330670409
更新日期:1985-08-01 00:00:00