Survival after stereotactic biopsy and irradiation of cerebral nonanaplastic, nonpilocytic astrocytoma.

Abstract:

:The authors investigated the outcome of stereotactic biopsy and radiotherapy in 35 consecutive adult patients with nonanaplastic, nonpilocytic astrocytomas who were diagnosed between 1982 and 1992. The median patient age at presentation was 32 years. All received fractionated external-beam radiation therapy (median dose 56 Gy) as the initial management strategy. Additional treatment in two patients included intracavitary irradiation with colloidal phosphorus-32. Six patients (17%) had documented tumor progression during the follow-up interval and died. Three others died of causes unrelated to their tumor. Median survival after stereotactic biopsy and irradiation was 118 months (9.8 years). Median survival from the time of onset of neurological symptoms was 148 months (12.3 years). Only three patients required delayed cytoreductive surgery. The outcome of brain astrocytomas, although improved because of earlier diagnosis and therapy, does not substantiate this tumor as having benign behavior; early recognition with neuroimaging, immediate histological diagnosis via stereotactic biopsy, and initial fractionated radiation therapy may provide the potential for longer survival for patients with low-grade astrocytomas. The majority of such surviving patients have a satisfactory quality of life, which is manifested by prolonged normal functional and employment status. The survival data reported in this prospective Phase I-II clinical trial suggest that stereotactic biopsy and radiation therapy are appropriate initial management strategies for astrocytomas.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Lunsford LD,Somaza S,Kondziolka D,Flickinger JC

doi

10.3171/jns.1995.82.4.0523

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

523-9

issue

4

eissn

0022-3085

issn

1933-0693

journal_volume

82

pub_type

临床试验,杂志文章
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    doi:10.3171/jns.1987.66.4.0548

    authors: Nagao S,Nishiura T,Kuyama H,Suga M,Murota T

    更新日期:1987-04-01 00:00:00

  • Management of accidental minor head injuries in children: a prospective outcomes study.

    abstract:OBJECT:The authors conducted a study to determine clinical, patient/family satisfaction, and financial outcomes following application of a management scheme that involves evaluation of computerized tomography (CT) scans and emergency department observation, rather than overnight admission, for children who have sustain...

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    doi:10.3171/ped.2004.101.2.0038

    authors: Dias MS,Lillis KA,Calvo C,Shaha SH,Li V

    更新日期:2004-08-01 00:00:00

  • Injury outcomes in children following automobile, motorcycle, and all-terrain vehicle accidents: an institutional review.

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    doi:10.3171/ped.2006.105.3.182

    authors: Miller B,Baig M,Hayes J,Elton S

    更新日期:2006-09-01 00:00:00

  • Polymorphism rs42524 of COL1A2 and sporadic intracranial aneurysms in the Chinese population.

    abstract:OBJECT:The COL1A2 gene at 7q22.1 has been shown to be associated with familial intracranial aneurysms (IAs) in the Japanese population. In the present study, the authors investigated the correlation between the presence of the rs42524 polymorphism in COL1A2 and the occurrence of sporadic IAs in Chinese patients. METHO...

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    doi:10.3171/JNS.2008.109.12.1060

    authors: Zhu Y,Li W,Ge M,Xu S,Zhao G,Wang H,Qian H,Zhu N,Pang Q

    更新日期:2008-12-01 00:00:00

  • Comparison of robotic-assisted carotid stenting and manual carotid stenting through the transradial approach.

    abstract:OBJECTIVE:The objective of this study was to demonstrate the feasibility and safety of CorPath GRX robotic-assisted (RA) transradial (TR) carotid artery stenting (CAS) compared with manual TR CAS. METHODS:The authors conducted a retrospective analysis of a prospectively maintained database and identified 13 consecutiv...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2020.5.JNS201421

    authors: Weinberg JH,Sweid A,Sajja K,Gooch MR,Herial N,Tjoumakaris S,Rosenwasser RH,Jabbour P

    更新日期:2020-08-28 00:00:00

  • Ultrasound diagnosis of an intraneural ganglion cyst of the peroneal nerve. Case report.

    abstract::The authors present the case of an intraneural ganglion cyst of the peroneal nerve. The cyst was diagnosed by means of ultrasound, which also gave an exact definition of its size and location, confirmed at operation. Some controversial aspects of these lesions are discussed. ...

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    pub_type: 杂志文章

    doi:10.3171/jns.1992.76.3.0538

    authors: Leijten FS,Arts WF,Puylaert JB

    更新日期:1992-03-01 00:00:00

  • Spinal cord injury.

    abstract:OBJECT:It is known that the spinal cord can sustain traumatic injury without associated injury of the spinal column in some conditions, such as a flexible spinal column or preexisting narrowed spinal canal. The purpose of this study was to characterize the clinical features and to understand the mechanisms in cases of ...

    journal_title:Journal of neurosurgery

    pub_type: 评论,信件

    doi:

    authors: Bhatoe HS

    更新日期:2001-04-01 00:00:00

  • Analysis of treatment failure after radiosurgery for arteriovenous malformations.

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    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1998.89.1.0104

    authors: Ellis TL,Friedman WA,Bova FJ,Kubilis PS,Buatti JM

    更新日期:1998-07-01 00:00:00

  • Cerebrovascular CO2 reactivity after carotid artery occlusion.

    abstract::Cerebral blood flow (CBF) was measured in 39 men at normocapnia and after 5% CO2 inhalation using the xenon-133 technique. Twenty-three patients had unilateral carotid artery occlusion with no angiographic evidence of contralateral carotid artery stenosis or ophthalmic collateral flow. Eleven of these patients had und...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1988.69.1.0024

    authors: Clifton GL,Haden HT,Taylor JR,Sobel M

    更新日期:1988-07-01 00:00:00

  • Long-term motor outcome analysis using a motor score composite following surgical brachial plexus repair.

    abstract:OBJECT:Due to the complex and variable nature of brachial plexus injury, outcome analysis can be cumbersome and imprecise. Many scales have been devised, but no single scale is used uniformly. Moreover, despite several studies in which the authors have reported brachial plexus surgical data, no highly predictive clinic...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2007.106.4.276

    authors: Ashley WW Jr,Baty JD,Hollander T,Noetzel MJ,Park TS

    更新日期:2007-04-01 00:00:00

  • Falcine sinus and occipital encephalocele: a magnetic resonance venography study.

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    pub_type: 杂志文章

    doi:10.3171/jns.1998.89.5.0738

    authors: Bartels RH,Merx JL,van Overbeeke JJ

    更新日期:1998-11-01 00:00:00

  • Intracranial desmoplastic small round cell tumor presenting as a suprasellar mass.

    abstract::Desmoplastic small round cell tumors (DSRCTs) are rare, aggressive neoplasms that typically arise from abdominal and pelvic peritoneum in young adults. Other primary sites are uncommon, and an intracranial origin is exceptionally rare. Here the authors report the first case of a DSRCT presenting as a primary suprasell...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.10.JNS132490

    authors: Thondam SK,du Plessis D,Cuthbertson DJ,Das KS,Javadpour M,MacFarlane IA,Leggate J,Haylock B,Daousi C

    更新日期:2015-04-01 00:00:00

  • Reinvestigation of the ambient cistern and its related arachnoid membranes: an anatomical study.

    abstract:OBJECT:A precise understanding of the ambient cistern and its associated arachnoid membranes is helpful for accessing perimesencephalic lesions. However, few studies of the arachnoid membranes related to the ambient cistern have been published, and, additionally, some aspects of the ambient cistern also require further...

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    doi:10.3171/2011.2.JNS101365

    authors: Qi ST,Fan J,Zhang XA,Pan J

    更新日期:2011-07-01 00:00:00

  • Predictors of 30-day readmission after aneurysmal subarachnoid hemorrhage: a case-control study.

    abstract::OBJECTIVE Despite persisting questions regarding its appropriateness, 30-day readmission is an increasingly common quality metric used to influence hospital compensation in the United States. However, there is currently insufficient evidence to identify which patients are at highest risk for readmission after aneurysm...

    journal_title:Journal of neurosurgery

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    doi:10.3171/2016.5.JNS152644

    authors: Greenberg JK,Guniganti R,Arias EJ,Desai K,Washington CW,Yan Y,Weng H,Xiong C,Fondahn E,Cross DT,Moran CJ,Rich KM,Chicoine MR,Dhar R,Dacey RG Jr,Derdeyn CP,Zipfel GJ

    更新日期:2017-06-01 00:00:00

  • Relationship of intraoperative electrophysiological criteria to outcome after selective functional posterior rhizotomy.

    abstract::At British Columbia's Children's Hospital, the criteria used in selective functional posterior rhizotomy (SFPR) evolved in three distinct phases. In Phase 1 the electrophysiological criteria for abnormality included a low threshold to a single stimulation, a sustained response to 50-Hz stimulation, and spread outside ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.1.0018

    authors: Steinbok P,Gustavsson B,Kestle JR,Reiner A,Cochrane DD

    更新日期:1995-07-01 00:00:00

  • The clinical application of plugging patterns for the Leksell gamma knife.

    abstract:OBJECT:In this report the authors explore the use of standardized plugging templates in formulating stereotactic radiosurgery dose plans for the Leksell gamma knife. METHODS:Unplugged gamma knife dose plans previously used in the treatment of patients with trigeminal neuralgia (TN) and vestibular schwannoma (VS) were ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2002.97.supplement

    authors: Vaughan P,Hampshire A,Soanes T,Kemeny A,Radatz M,Rowe J,Walton L

    更新日期:2002-12-01 00:00:00

  • Brain-cutting device for correlation of brain scan and autopsy sections. Technical note.

    abstract::The authors describe a frame with guides to facilitate accurate correlation of the planes of brain-specimen sections with computerized axial tomography brain scans. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1976.44.6.0759

    authors: Shipps FC,D'Agostino A,Raaf J

    更新日期:1976-06-01 00:00:00

  • Role of superior hypophyseal artery in visual function impairment after paraclinoid carotid artery aneurysm surgery.

    abstract:OBJECT:Although a number of studies have assessed the surgical treatment of paraclinoid-segment carotid artery aneurysms and resulting visual complications, less attention has been given to the results with respect to the superior hypophyseal artery (SHA). The authors evaluated the relationship between the aneurysm, th...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.12.JNS141218

    authors: Horiuchi T,Goto T,Tanaka Y,Kodama K,Tsutsumi K,Ito K,Hongo K

    更新日期:2015-08-01 00:00:00

  • Evolution of the graded repair of CSF leaks and skull base defects in endonasal endoscopic tumor surgery: trends in repair failure and meningitis rates in 509 patients.

    abstract:Objective:The authors previously described a graded approach to skull base repair following endonasal microscopic or endoscope-assisted tumor surgery. In this paper they review their experience with skull base reconstruction in the endoscopic era. Methods:A retrospective review of a single-institution endonasal endosc...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2017.11.JNS172141

    authors: Conger A,Zhao F,Wang X,Eisenberg A,Griffiths C,Esposito F,Carrau RL,Barkhoudarian G,Kelly DF

    更新日期:2018-05-11 00:00:00

  • Risk of rupture associated with intact cerebral aneurysms in the Japanese population: a systematic review of the literature from Japan.

    abstract:OBJECT:Knowing the rate of rupture associated with unruptured cerebral aneurysms (UCAs) can help surgeons determine a case management strategy in patients harboring these lesions. According to large-scale cohort studies involving populations in North America and Europe, small unruptured aneurysms carry a very low risk ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2005.102.4.0601

    authors: Morita A,Fujiwara S,Hashi K,Ohtsu H,Kirino T

    更新日期:2005-04-01 00:00:00

  • A meningioma and its consequences for American history and the rise of neurosurgery.

    abstract::The case of General Leonard Wood is notable both for its contribution to the field of neurosurgery and its historical significance. As one of Harvey Cushing's first successful brain tumor operations in 1910, Wood's surgery was part of the case series that culminated in Cushing's monograph Meningioma. This case was imp...

    journal_title:Journal of neurosurgery

    pub_type: 传,历史文章,杂志文章

    doi:10.3171/2011.7.JNS102067

    authors: Ansari SF,Gianaris NG,Cohen-Gadol AA

    更新日期:2011-12-01 00:00:00

  • Premorbid oral antithrombotic therapy and risk for reaccumulation, reoperation, and mortality in acute subdural hematomas.

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    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.7.JNS10446

    authors: Panczykowski DM,Okonkwo DO

    更新日期:2011-01-01 00:00:00

  • Dorsal root entry zone lesions for the treatment of post-herpetic neuralgia.

    abstract::Post-herpetic pain was treated in 12 patients using dorsal root entry zone ( DREZ ) lesions. All patients had failed to receive adequate pain relief from conservative therapy consisting of transcutaneous nerve stimulation, carbamazepine, and/or amitriptyline. Dorsal root entry zone lesions were made to include the inv...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.6.1258

    authors: Friedman AH,Nashold BS Jr,Ovelmen-Levitt J

    更新日期:1984-06-01 00:00:00

  • The role of endoscopic third ventriculostomy in adult patients with hydrocephalus.

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    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2008.10.JNS17667

    authors: Jenkinson MD,Hayhurst C,Al-Jumaily M,Kandasamy J,Clark S,Mallucci CL

    更新日期:2009-05-01 00:00:00

  • Incidence and clinicopathological features of meningioma.

    abstract::The incidence of intracranial meningioma in Manitoba, Canada, was reviewed from 1980 through 1987. During that time, 193 tumors were diagnosed, with a male:female ratio of 1:2. This occurrence corresponded to crude incidence rates of 2.3/100,000 for all meningiomas and 0.17/100,000 for malignant meningiomas. Among mal...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.71.5.0665

    authors: Rohringer M,Sutherland GR,Louw DF,Sima AA

    更新日期:1989-11-01 00:00:00

  • Extended endoscopic endonasal approach for selected pituitary adenomas: early experience.

    abstract:OBJECT:Whereas most pituitary adenomas are removable via the transsphenoidal approach, certain cases, such as dumbbell-shaped or suprasellar adenomas and recurrent and/or fibrous tumors, remain difficult to treat. The authors present their experience with the extended endoscopic endonasal approach to the suprasellar ar...

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    pub_type: 杂志文章

    doi:10.3171/2010.9.JNS10262

    authors: Di Maio S,Cavallo LM,Esposito F,Stagno V,Corriero OV,Cappabianca P

    更新日期:2011-02-01 00:00:00

  • Quantification of thermal asymmetry. Part 2: Application in low-back pain and sciatica.

    abstract::Temperature differences between the lower extremities were measured using a computerized thermometric scanning system in order to compare the degree of thermal asymmetry in 144 patients with low-back pain. The patients displayed highly significant thermal asymmetries, with the involved limb being cooler (p less than 0...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1988.69.4.0556

    authors: Uematsu S,Jankel WR,Edwin DH,Kim W,Kozikowski J,Rosenbaum A,Long DM

    更新日期:1988-10-01 00:00:00

  • Reversible facial pain due to hydrocephalus with trigeminal somatosensory evoked response changes. Case report.

    abstract::A patient with hydrocephalus due to aqueductal stenosis suffered facial pain which was relieved after the insertion of a ventriculoperitoneal shunt. The trigeminal somatosensory evoked response (TSER) of the affected side showed lower amplitudes and longer latencies as compared to the unaffected side. Following surger...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1982.57.2.0267

    authors: Findler G,Feinsod M

    更新日期:1982-08-01 00:00:00

  • Resolution of brain edema in severe brain injury at controlled high and low intracranial pressures.

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    pub_type: 杂志文章

    doi:10.3171/jns.1984.61.4.0707

    authors: Cao M,Lisheng H,Shouzheng S

    更新日期:1984-10-01 00:00:00

  • Thalamic deep brain stimulation for writer's cramp.

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    authors: Fukaya C,Katayama Y,Kano T,Nagaoka T,Kobayashi K,Oshima H,Yamamoto T

    更新日期:2007-11-01 00:00:00