A meningioma and its consequences for American history and the rise of neurosurgery.

Abstract:

:The case of General Leonard Wood is notable both for its contribution to the field of neurosurgery and its historical significance. As one of Harvey Cushing's first successful brain tumor operations in 1910, Wood's surgery was part of the case series that culminated in Cushing's monograph Meningioma. This case was important to the rise of Cushing's career and his recognition as a member of the next generation of neurosurgeons who did not settle for mere bony decompression to taper intracranial tension but who dared to pursue intradural resections-operations that had been performed by surgeons for decades but were frowned upon because of the attendant risks. Cushing's operation to remove a recurrent brain tumor ended Wood's life in 1927. The authors discuss the effects the tumor may have had on Wood's life and career, explore an alternate explanation for the cause of Wood's death, and provide a brief account of the life of General Wood, highlighting events in his military and administrative career juxtaposed against the progression of his illness. Furthermore, the case history of the General is reviewed, using information drawn from the original patient notes and recently discovered images from the Cushing Brain Tumor Registry that elucidate more details about General Wood's story, from the injury that caused his first tumor to his final surgery, leading to his demise.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Ansari SF,Gianaris NG,Cohen-Gadol AA

doi

10.3171/2011.7.JNS102067

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1067-71

issue

6

eissn

0022-3085

issn

1933-0693

journal_volume

115

pub_type

传,历史文章,杂志文章
  • Liposomes coupled with monoclonal antibodies against glioma-associated antigen for targeting chemotherapy of glioma.

    abstract::Liposomes have a variety of attributes as a drug delivery system. Targeting of liposomes to specific cells has been investigated by using appropriate cytophilic ligands such as monoclonal antibodies (MAb's). In the present study, liposomes with selective cytotoxicity toward glioma cells were obtained. An MAb which rea...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.71.3.0382

    authors: Kito A,Yoshida J,Kageyama N,Kojima N,Yagi K

    更新日期:1989-09-01 00:00:00

  • Protein kinase C and diacylglycerol content in basilar arteries during experimental cerebral vasospasm in the dog.

    abstract::Sixteen dogs were entered into a study of the double subarachnoid hemorrhage (SAH) model of cerebral vasospasm. Six animals were sacrificed 72 hours after the first experimental SAH, and the remaining 10 animals were killed 72 hours after the second experimental SAH; ten additional animals served as controls. Basilar ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.82.5.0834

    authors: Yokota M,Peterson JW,Kaoutzanis MC,Yamakawa K,Sibilia R,Zervas NT

    更新日期:1995-05-01 00:00:00

  • Cranial index of symmetry: an objective semiautomated measure of plagiocephaly. Technical note.

    abstract:OBJECT:The prevalence of deformational, or positional, plagiocephaly has increased during the last decade. Treatments vary among centers, ranging from expectant management to orthotic helmet therapy to craniofacial remodeling. This management variability is partially due to a lack of objective methods with which to mea...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2004.100.5.0537

    authors: Zonenshayn M,Kronberg E,Souweidane MM

    更新日期:2004-05-01 00:00:00

  • Surgically treated lumbar disc disease in the pediatric population: an outcome study.

    abstract:OBJECT:This outcome study was undertaken to investigate the long-term results obtained in surgically treated pediatric patients with lumbar disc disease by using standardized medical outcome scales and clinical follow-up examination. METHODS:Twenty nine patients 17 years of age or younger underwent surgery between 196...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2000.92.1.0001

    authors: Durham SR,Sun PP,Sutton LN

    更新日期:2000-01-01 00:00:00

  • Median to radial nerve transfer for treatment of radial nerve palsy. Case report.

    abstract::The purpose of this study is to report a surgical technique of nerve transfer to restore radial nerve function after a complete palsy due to a proximal injury to the radial nerve. The authors report the case of a patient who underwent direct nerve transfer of redundant or expendable motor branches of the median nerve ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS-07/09/0666

    authors: Mackinnon SE,Roque B,Tung TH

    更新日期:2007-09-01 00:00:00

  • Ultrasound diagnosis of an intraneural ganglion cyst of the peroneal nerve. Case report.

    abstract::The authors present the case of an intraneural ganglion cyst of the peroneal nerve. The cyst was diagnosed by means of ultrasound, which also gave an exact definition of its size and location, confirmed at operation. Some controversial aspects of these lesions are discussed. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1992.76.3.0538

    authors: Leijten FS,Arts WF,Puylaert JB

    更新日期:1992-03-01 00:00:00

  • Sulcus-centered resection for focal cortical dysplasia type II: surgical techniques and outcomes.

    abstract::Focal cortical dysplasia type II (FCD II) is a common histopathological substrate of epilepsy surgery. Here, the authors propose a sulcus-centered resection strategy for this malformation, provide technical details, and assess the efficacy and safety of this technique. The main purpose of the sulcus-centered resection...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2020.5.JNS20751

    authors: Zhao B,Zhang C,Wang X,Wang Y,Liu C,Mo J,Zheng Z,Zhang K,Shao XQ,Hu W,Zhang J

    更新日期:2020-08-07 00:00:00

  • Vestibular schwannoma management. Part I. Failed microsurgery and the role of delayed stereotactic radiosurgery.

    abstract:OBJECT:The purpose of this study was to analyze patient outcomes and to define the role of radiosurgery in patients who have undergone prior microsurgical resection of their vestibular schwannoma. METHODS:The authors evaluated the pre- and postoperative clinical and neuroimaging characteristics of 76 consecutive patie...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1998.89.6.0944

    authors: Pollock BE,Lunsford LD,Flickinger JC,Clyde BL,Kondziolka D

    更新日期:1998-12-01 00:00:00

  • Methylprednisolone and neurological function 1 year after spinal cord injury. Results of the National Acute Spinal Cord Injury Study.

    abstract::A multi-center double-blind randomized clinical trial was conducted by the National Acute Spinal Cord Injury Study Group to examine the efficacy of high-dose methylprednisolone (1000-mg bolus and 1000 mg daily thereafter for 10 days) compared with that of a standard dose (100-mg bolus and 100 mg daily for 10 days). No...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3171/jns.1985.63.5.0704

    authors: Bracken MB,Shepard MJ,Hellenbrand KG,Collins WF,Leo LS,Freeman DF,Wagner FC,Flamm ES,Eisenberg HM,Goodman JH

    更新日期:1985-11-01 00:00:00

  • Comparison of effects of socioeconomic and geographic variations on survival for adults and children with glioma.

    abstract:OBJECT:The authors analyzed the effects of socioeconomic status (SES) and geographic variations on survival rates for adults and children with glioma, studying the data of 30,489 adults and 2940 children from the Cancer Registry in England and Wales. METHODS:The median survival time and crude survival rates for eight ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2006.105.4.297

    authors: Tseng MY,Tseng JH,Merchant E

    更新日期:2006-10-01 00:00:00

  • Hemichorea due to hemodynamic ischemia associated with extracranial carotid artery stenosis. Report of two cases.

    abstract::In this paper the authors describe two patients with recurrent hemiparesis and limb shaking that gradually progressed to hemichorea. Cerebral angiography confirmed severe unilateral internal carotid artery stenosis (95%) contralateral to the hemichorea. The cerebral blood flow, assessed using N-isopropyl-p-(iodine-123...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.105.1.142

    authors: Morigaki R,Uno M,Suzue A,Nagahiro S

    更新日期:2006-07-01 00:00:00

  • Infundibular widening mimicking anterior communicating artery aneurysm: report of 2 cases.

    abstract::Because infundibular widening most commonly appears at the origins of the posterior communicating artery and anterior choroidal artery from the internal carotid artery, its occurrence in association with the anterior communicating artery (ACoA) or the A1-A2 junction can be misinterpreted as an ACoA aneurysm on angiogr...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2013.3.JNS122058

    authors: Park J,Kang DH

    更新日期:2013-07-01 00:00:00

  • Intradural extramedullary tuberculoma of the cervical spine. Case report.

    abstract::A case is reported of a 45-year-old man who developed quadriplegia following a trivial motor-vehicle accident. Investigation including computerized tomography (CT) of the cervical spine revealed a large calcified lesion displacing the spinal cord and nerve roots, which proved to be a tuberculoma. The case is unusual i...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.1.0200

    authors: Compton JS,Dorsch NW

    更新日期:1984-01-01 00:00:00

  • Toxoplasmosis of the conus medullaris in a patient with hemophilia A-associated AIDS. Case report.

    abstract::Toxoplasma gondii has been reported to be the most common cause of focal brain lesions in patients with acquired immunodeficiency syndrome (AIDS). A case of intramedullary toxoplasmosis of the conus medullaris is reported in a patient with hemophilia A-associated AIDS. The diagnosis is discussed, with particular empha...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1990.73.6.0951

    authors: Kayser C,Campbell R,Sartorious C,Bartlett M

    更新日期:1990-12-01 00:00:00

  • Spinal intramedullary cavernoma: clinical presentation and surgical outcome.

    abstract:OBJECT:Improved neuroimaging techniques have led to an increase in the reported cases of intramedullary cavernomas. The purpose of this study was to define the spectrum of presenting signs and symptoms in patients with spinal intramedullary cavernomas and to analyze the role of surgery as a treatment for these lesions....

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2000.93.1.0065

    authors: Deutsch H,Jallo GI,Faktorovich A,Epstein F

    更新日期:2000-07-01 00:00:00

  • Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction.

    abstract::OBJECTIVE: Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult bone marrow improves behavioral function in rat models of cerebral infarction. Although clinical studies are ongoing, most studies have focused on the acute or subacute phase of stroke. In the present study, MSCs derived from bone marr...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.5.JNS18140

    authors: Namioka T,Namioka A,Sasaki M,Kataoka-Sasaki Y,Oka S,Nakazaki M,Onodera R,Suzuki J,Sasaki Y,Nagahama H,Kocsis JD,Honmou O

    更新日期:2018-10-01 00:00:00

  • The management of ruptured intracranial aneurysm in sickle cell anemia. Case report.

    abstract::The problems of sickle cell disease and its complications is discussed. Subarachnoid hemorrhage is not a common complication of sickle cell disease and should be evaluated in the same way as if it were not associated with the disease. Patients with sickle cell trait have an added risk during angiography and hypotensiv...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1977.47.5.0761

    authors: Close RA,Buchheit WA

    更新日期:1977-11-01 00:00:00

  • Neuroendoscopic fenestration of glioependymal cysts to the ventricle: report of 3 cases.

    abstract::Glioependymal cysts are rare congenital lesions of the central nervous system. Reported surgical treatments of these lesions have varied and yielded mixed results, and the optimal surgical strategy is still controversial. The authors here report the clinical and surgical outcomes for three adult patients successfully ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.7.JNS172501

    authors: Alvarado AM,Smith KA,Chamoun RB

    更新日期:2018-11-01 00:00:00

  • Scar formation in the carotid sheath identified during carotid endarterectomy in patients with previous cardiac surgery: significance of history of intraoperative Swan-Ganz catheter insertion. Clinical article.

    abstract:OBJECT:Scar formation in the carotid sheath is often identified during carotid endarterectomy (CEA) in patients with previous cardiac surgery, and dissection of the carotid sheath and exposure of the carotid arteries in such patients are difficult. The purpose of the present study was to investigate factors related to ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.4.JNS091819

    authors: Yoshida K,Ogasawara K,Kobayashi M,Tsuboi J,Okabayashi H,Ogawa A

    更新日期:2010-10-01 00:00:00

  • Surgical treatment of patients with vestibular schwannomas after failed previous radiosurgery.

    abstract:OBJECT:An increasing number of patients with vestibular schwannomas (VSs) are being treated with radiosurgery. Treatment failure or secondary regrowth after radiosurgery, however, has been observed in 2%-9% of patients. In large tumors that compress the brainstem and in patients who experience rapid neurological deteri...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2011.12.JNS111682

    authors: Gerganov VM,Giordano M,Samii A,Samii M

    更新日期:2012-04-01 00:00:00

  • Efficacy of deep rTMS for neuropathic pain in the lower limb: a randomized, double-blind crossover trial of an H-coil and figure-8 coil.

    abstract::OBJECTIVE Electrical motor cortex stimulation can relieve neuropathic pain (NP), but its use requires patients to undergo an invasive procedure. Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) using a figure-8 coil can relieve NP noninvasively, but its ability to relieve lower limb...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,随机对照试验

    doi:10.3171/2016.9.JNS16815

    authors: Shimizu T,Hosomi K,Maruo T,Goto Y,Yokoe M,Kageyama Y,Shimokawa T,Yoshimine T,Saitoh Y

    更新日期:2017-11-01 00:00:00

  • Computer-derived density spectral array in detection of mild analog electroencephalographic ischemic pattern changes during carotid endarterectomy.

    abstract::The purpose of this prospective study was twofold: 1) to determine the sensitivity and specificity of computer-derived density spectral array in detecting analog electroencephalographic (EEG) ischemic pattern changes during carotid artery cross-clamping in patients undergoing carotid endarterectomy; and 2) to assess t...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1993.78.6.0884

    authors: Kearse LA Jr,Martin D,McPeck K,Lopez-Bresnahan M

    更新日期:1993-06-01 00:00:00

  • Contralateral vertebral approach for stenting and coil embolization of a large, thrombosed vertebral-posterior inferior cerebellar artery aneurysm. Case report.

    abstract::The authors report the successful staged stenting and coil embolization of a large vertebral artery-posterior inferior cerebellar artery (VA-PICA) aneurysm using the contralateral VA for access. A 67-year-old woman presented with a large ruptured VA-PICA aneurysm. Initial attempts to stent the wide-necked aneurysm fro...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS-07/12/1214

    authors: Ecker RD,Hanel RA,Levy EI,Hopkins LN

    更新日期:2007-12-01 00:00:00

  • VOLUMESERIES: a software tool for target volume follow-up studies with computerized tomography and magnetic resonance imaging. Technical note.

    abstract::In clinical follow-up studies after radiosurgery, imaging modalities such as computerized tomography (CT) and magnetic resonance (MR) imaging are used. Accurate determination of the residual lesion volume is necessary for realistic assessment of the effects of treatment. Usually, the diameters rather than the volume o...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2000.93.supplement

    authors: Scheib SG,Gianolini S,Haller D,Wellis GN,Siegfried J

    更新日期:2000-12-01 00:00:00

  • The transfacet pedicle-sparing approach for thoracic disc removal: cadaveric morphometric analysis and preliminary clinical experience.

    abstract::A number of operative techniques have been described for the treatment of herniated thoracic discs. The transfacet pedicle-sparing approach allows for complete disc removal with limited spinal column disruption and soft-tissue dissection. Fifteen cadaveric spinal columns were used for evaluation of exposure, developme...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.6.0971

    authors: Stillerman CB,Chen TC,Day JD,Couldwell WT,Weiss MH

    更新日期:1995-12-01 00:00:00

  • Salvage retreatment after failure of radiosurgery in patients with arteriovenous malformations.

    abstract:OBJECT:The goal of this study was to evaluate the outcomes of patients who underwent repeated radiosurgery to treat a residual intracranial arteriovenous malformation (AVM) after an initial radiosurgical treatment failure. METHODS:The authors reviewed the cases of 52 patients who underwent repeated radiosurgery for re...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2003.98.2.0337

    authors: Foote KD,Friedman WA,Ellis TL,Bova FJ,Buatti JM,Meeks SL

    更新日期:2003-02-01 00:00:00

  • Resveratrol targeting of AKT and p53 in glioblastoma and glioblastoma stem-like cells to suppress growth and infiltration.

    abstract::OBJECTIVE Glioblastoma multiforme (GBM) is an aggressive brain cancer with median survival of less than 2 years with current treatment. Glioblastomas exhibit extensive intratumoral and interpatient heterogeneity, suggesting that successful therapies should produce broad anticancer activities. Therefore, the natural no...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.1.JNS152077

    authors: Clark PA,Bhattacharya S,Elmayan A,Darjatmoko SR,Thuro BA,Yan MB,van Ginkel PR,Polans AS,Kuo JS

    更新日期:2017-05-01 00:00:00

  • Transarterial embolization of vein of Galen malformations: the use of magnetic resonance imaging noninvasive optimal vessel analysis to quantify shunt reduction. Report of two cases.

    abstract::In patients with vein of Galen malformations, high-flow shunting decreases cerebral perfusion. By reducing or eliminating these shunts, transarterial embolization can improve cerebral perfusion and clinical outcomes. Quantifying pre- and postembolization shunt blood flow may help determine the optimal timing and effic...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2006.104.1.41

    authors: Langer DJ,Song JK,Niimi Y,Chwajol M,Lefton DR,Brisman JL,Molofsky W,Kupersmith MJ,Berenstein A

    更新日期:2006-01-01 00:00:00

  • Risk of rupture associated with intact cerebral aneurysms in the Japanese population: a systematic review of the literature from Japan.

    abstract:OBJECT:Knowing the rate of rupture associated with unruptured cerebral aneurysms (UCAs) can help surgeons determine a case management strategy in patients harboring these lesions. According to large-scale cohort studies involving populations in North America and Europe, small unruptured aneurysms carry a very low risk ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2005.102.4.0601

    authors: Morita A,Fujiwara S,Hashi K,Ohtsu H,Kirino T

    更新日期:2005-04-01 00:00:00

  • Usefulness of inferior petrosal sinus venous endocrine markers in Cushing's disease.

    abstract::Bilateral and simultaneous sampling of the inferior petrosal sinuses in patients with Cushing's disease has been used to establish the presence and laterality of adrenocorticotropic hormone (ACTH)-producing microadenomas prior to transsphenoidal surgery. Successful preoperative lateralization depends upon equivalent d...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1988.68.2.0205

    authors: Zovickian J,Oldfield EH,Doppman JL,Cutler GB Jr,Loriaux DL

    更新日期:1988-02-01 00:00:00