Abstract：
:The propensity of crosslinked collagen matrices to calcify when implanted in animals and human beings is well documented. This article demonstrates that the covalent binding of the biphosphonate, 3-amino-1-hydroxy-propane-1-1-diphosphonic acid, to active bone matrix inhibits bone formation as well as dystrophic calcification. The inhibitory effects on calcium accumulation and alkaline phosphatase activity are greater than those achieved by inactivation of the matrix by protease digestion of the bone morphogenetic factors present in demineralized bone. Whereas bone formation is a cell-mediated effect, artificially crosslinked collagen matrices calcify extensively inside diffusion chambers, reflecting a non-cell-mediated nucleation process. The fundamental differences described should shed light on new modalities to modulate these processes in living systems.
journal_name
Clin Plast Surgjournal_title
Clinics in plastic surgeryauthors
Nimni MEsubject
Has Abstractpub_date
1994-07-01 00:00:00pages
419-27issue
3eissn
0094-1298issn
1558-0504journal_volume
21pub_type
杂志文章abstract：:The goal in breast reduction surgery is to reduce volume but at the same time to maintain circulation, sensation and breast feeding potential. A dermoglandular or central pedicle is the most likely to achieve all three. The superior pedicle is reserved mainly for very small reductions or mastopexies, but the author st...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/s0094-1298(02)00004-4
更新日期：2002-07-01 00:00:00
abstract：:Despite a better appreciation of the relationship between the eye and the thyroid gland in Graves' disease, the treatment of moderate to severe exophthalmos remains surgical. For many years, standard textbooks recommended a risky, transfrontal approach for exophthalmos that had to be performed by a neurosurgeon. A pre...
journal_title：Clinics in plastic surgery
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：:I believe that if one follows the precautions outlined, including a time-tested surgical technique and thorough clinical history and physical examination, the operation of blepharoplasty should prove to be one of the most gratifying aesthetic operations. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The success of a denture is dependent on a good foundation; therefore, construction of the prosthesis begins with extraction of the teeth. The teeth should be maintained as long as possible if they can be restored. When the teeth are extracted, bone resorption usually starts, owing to systemic and local factors. Good ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1989-10-01 00:00:00
abstract：:Lockwood's changes in surgical design of the medial thigh lift have improved results and decreased complications but still have the fundamental problem of poor tissue fixation to rigid tissue. To provide increased support to the medial thigh incisions, modifications to this technique have been tried. This article desc...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2007.09.003
更新日期：2008-01-01 00:00:00
abstract：:In composite rhytidectomy, all of the deep aging anatomic components of the midface are elevated in the skin flap. The platysma muscle, cheek fat, and orbicularis oculi muscle are repositioned in this bipedicled musculocutaneous flap, which very effectively improves the nasolabial fold. Repositioning of all of the dee...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:Marked technical improvements in the surgical management of craniosynostosis have come hand-in-hand with refinements in anesthesia, intensive care, and radiographic image analysis. At the beginning of the second century of the care of these patients, we now have a variety of sophisticated options that represent safer,...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1997-07-01 00:00:00
abstract：:This article presents a survey of some of the nonpigmented cutaneous lesions that have the propensity or possibility to progress or transform into malignancies. For each lesion, the author discusses clinical appearance and course, histologic features, and general recommendations for treatment. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1987-04-01 00:00:00
abstract：:Experimental and clinical cases document that the omentum and jejunum can be harvested successfully as a free flap using laparoscopic assistance. Our gross and microscopic findings attest to the viability of this approach. If the omentum is not needed in it entirety, one can safely custom design the free flap to match...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：:The authors discuss how, in performing an endoscopic brow lift, meticulous surgical technique, adherence to anatomic dissection planes, and direct visualization used at key points in the procedure enable a safer, more-complete dissection and a better outcome. Anatomy as it relates to the procedure is discussed. Patien...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2012.06.004
更新日期：2013-01-01 00:00:00
abstract：:This article supplies an introduction to the structure and purpose of managed care financial incentives, with particular attention to those affecting referrals to specialists. It then addresses some of the ethical problems attending such incentive schemes and discusses the characteristics that make some financial ince...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Radiofrequency (RF)-based devices are used to improve face and neck laxity, a major feature of aging that until recently could only be addressed with surgery. Although these treatments are not meant to replace surgical procedures, patient satisfaction studies have been consistently high. For physicians offering these ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2016.03.014
更新日期：2016-07-01 00:00:00
abstract：:Total mastectomy is an effective operation for patients who are candidates for a prophylactic mastectomy. This operation removes a larger percentage of breast tissue than subcutaneous mastectomy. The cosmetic results of total mastectomy with immediate reconstruction compare favorably with those of subcutaneous mastect...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:This article underscores the importance of the growth process in the production of normal and abnormal craniofacial morphology. Although much has been learned over the past century, we still have only a limited appreciation of the 3D changes that occur in the skull during postnatal growth. We have also stressed that t...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：:In plastic surgery, there are many procedures that can be performed using local instead of general anesthesia. Not only can this help mitigate health care costs, but precious operating-room resources can also be directed to areas of greater need. Common procedures that can be performed under local anesthetics include ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2013.07.004
更新日期：2013-10-01 00:00:00
abstract：:Aesthetic rhinoplasty in the non-Caucasian patient is a challenging operation, even to the experienced rhinoplastic surgeon used to operating on Caucasians. Only by thoroughly understanding the anatomic differences between the Caucasian and non-Caucasian nose can the plastic surgeon effectively manipulate the various ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1987-10-01 00:00:00
abstract：:This article reviews 5 areas in burn care that increasingly use evidence-based medicine to optimize quality and safety: resuscitation protocols, transfusion practices, vascular access, venous thromboembolic prophylaxis, and rational use of antibiotics. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2017.02.015
更新日期：2017-07-01 00:00:00
abstract：:The technique of dermal suspension, parenchymal reshaping mastopexy is a useful procedure for patients with massive weight loss with a typical presentation. The operation is tailored to the individual deformity, powerfully reshapes the breast, and can be safely combined with other commonly performed procedures. It is ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2018.08.009
更新日期：2019-01-01 00:00:00
abstract：:In summary, the commonest late physical complications of the burn injury have been reviewed and an approach to their management described. An understanding of the pathophysiology of the conditions is invaluable in planning one's approach to these problems. The techniques to control and correct chronic wound and hypert...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1977-10-01 00:00:00
abstract：:Great progress has been made in both the basic science and the clinical knowledge base used in orbital reconstruction. With this, increasing complex orbital reconstructive problems are better managed. The diagnosis, treatment plan, and the actual reconstruction have evolved to a higher level. Several areas of progress...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Reconstructive surgery of the nasolacrimal duct, or dacryocystorhinostomy, can be performed via an external or endonasal approach. For almost a century external dacryocystorhinostomy was the gold standard for correction of lacrimal duct obstruction. The endonasal approach became a safe surgical procedure using endosco...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2009.02.002
更新日期：2009-07-01 00:00:00
abstract：:The concept of female beauty has changed throughout time, but the form and size of the breasts and gluteal region have remained constant as symbols of maximum femininity. Sculptures and prints show us feminine figures that are voluminous and reflect human history's interest in fertility. The early years of gluteal aug...
journal_title：Clinics in plastic surgery
pub_type： 历史文章,杂志文章
doi：10.1016/j.cps.2006.04.003
更新日期：2006-07-01 00:00:00
abstract：:Microvascular ear replantation is a rare event, having been reported only 25 times since the first case in 1980. It requires a lengthy operative time and hospital stay, results in multiple blood transfusions, and has a significant failure rate. Nevertheless, a successful ear replantation is a dramatic demonstration of...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/s0094-1298(01)00009-8
更新日期：2002-04-01 00:00:00
abstract：:Pediatric plastic surgery research is a rapidly expanding field. Unique in many ways, researchers in this field stand at the union of multiple scientific specialties, including biomedical engineering, tissue engineering, polymer science, molecular biology, developmental biology, and genetics. The goal of this scientif...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2004.10.003
更新日期：2005-01-01 00:00:00
abstract：:Lipoplasty accomplishes the opposite of classic plastic surgery results. Instead of a long incision, there is a tiny one; instead of undermining, tunneling is performed; instead of redraping and resection of the skin, lipoplasty uses skin retraction. Retraction versus traction is the key principle of liposuction. The ...
journal_title：Clinics in plastic surgery
pub_type： 历史文章,杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:The most common complication of blepharoplasty is an unnatural distortion of the lower eyelid. Identification of the underlying anatomic deformities dictates the reconstructive procedures. Emphasis is placed on utilization of the dermal-orbicular pennant lateral canthoplasty. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：:The primary goal of engineering cartilage as a therapeutic approach is to restore the physiological conditions of an affected or defective tissue in the body. Cartilage tissue is distributed widely in the human body and possesses an organization related to the specific demand of a particular anatomical region. In sele...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/s0094-1298(03)00070-1
更新日期：2003-10-01 00:00:00
abstract：:Craniofacial growth is a complex phenomenon. Knowing the starting blocks and the ultimate function, the pathways leading to the "finished product" become only a matter of connecting the dots. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:The two stage principle is one of the most important features of the procedure. It allows starting the operation at a very early stage (one to six months). The donor area in the periphery is very well supplied, therefore as many facial fascicles as necessary can be sacrificed on the healthy side. We have never noticed...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1979-07-01 00:00:00
abstract：:Each year, there are as many cases of nonmelanoma skin cancer as all other cancers combined. Although there is relatively low attributable mortality, the morbidity and expense of treatment is significant. Unlike many other malignancies, host and environmental factors relevant to the pathophysiology have been clearly d...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2004.11.009
更新日期：2005-04-01 00:00:00
