The effect of relaxin on the musculoskeletal system.

Abstract:

:Relaxin is a hormone structurally related to insulin and insulin-like growth factor, which exerts its regulatory effect on the musculoskeletal and other systems through binding to its receptor in various tissues, mediated by different signaling pathways. Relaxin alters the properties of cartilage and tendon by activating collagenase. This hormone is also involved in bone remodeling and healing of injured ligaments and skeletal muscle. In this review, we have summarized the literature on the effect of relaxin in musculoskeletal system to provide a broad perspective for future studies in this field.

journal_name

Scand J Med Sci Sports

authors

Dehghan F,Haerian BS,Muniandy S,Yusof A,Dragoo JL,Salleh N

doi

10.1111/sms.12149

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

e220-9

issue

4

eissn

0905-7188

issn

1600-0838

journal_volume

24

pub_type

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