Combination transcranial direct current stimulation and virtual reality therapy for upper extremity training in patients with subacute stroke.

Abstract:

OBJECTIVE:To investigate the effects of combination cathodal transcranial direct current stimulation (tDCS) and virtual reality (VR) therapy for upper extremity (UE) training in patients with subacute stroke. DESIGN:Pilot randomized controlled trial. Patients were randomly assigned to 1 of 3 groups: group A received cathodal tDCS, group B received VR, and group C received combination therapy (cathodal tDCS was simultaneously applied during VR therapy). SETTING:University hospital. PARTICIPANTS:Patients (N=59) with impaired unilateral UE motor function after stroke. INTERVENTION:Fifteen sessions of treatment over a 3-week period. MAIN OUTCOME MEASURES:The Modified Ashworth Scale, manual muscle test (MMT), Manual Function Test (MFT), Fugl-Meyer Scale (FMS), and Box and Block Test were used to assess UE function. To evaluate activities of daily living, the Korean-Modified Barthel Index (K-MBI) was used. All outcomes were measured before and immediately after treatment. RESULTS:After treatment, all groups demonstrated significant improvements in MMT, MFT, FMS, and K-MBI scores. The change in MFT and FMS scores was different between the 3 groups. Post hoc analysis revealed that the improvement of MFT and FMS scores in group C was significantly higher than those of the other 2 groups. CONCLUSIONS:In the present pilot study, the combination of brain stimulation using tDCS and peripheral arm training using VR could facilitate a stronger beneficial effect on UE impairment than using each intervention alone. This combination therapy might be a helpful method to enhance recovery of the paretic UE in patients with stroke.

journal_name

Arch Phys Med Rehabil

authors

Lee SJ,Chun MH

doi

10.1016/j.apmr.2013.10.027

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

431-8

issue

3

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(13)01130-1

journal_volume

95

pub_type

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