Abstract:
:58 cases of breast cancer treated primarily by radiotherapy were evaluated to determine the optimum dose for local control. Of 36 patients with T1 + T2 lesions who had tumorectomy prior to radiotherapy, incomplete excision of tumor was demonstrated on microscopic examination in 18. The minimum tumor dose to the breast was 4,500 rads in 5 weeks. Treatment failed to control local tumor in only 2 (5%) and metastases in 1.26 (72%) remained disease-free for 2 to 9 years. Of the 22 patients with T3 + T4 lesions, treatment failed to control both local tumor and metastases in 12 (54%); in those who received 6,000 rads or less in 6 weeks, treatment failed to control any of these lesions. 4,500-5,500 rads controlled the tumor in 95% of those with NO + N1 disease, compared to only half of those with N2 + N3 tumors.
journal_name
Radiologyjournal_title
Radiologyauthors
Ghossein NA,Stacey P,Alpert RT,Ager PJ,Krishnaswamy Vdoi
10.1148/121.2.455subject
Has Abstractpub_date
1976-11-01 00:00:00pages
455-9issue
2eissn
0033-8419issn
1527-1315journal_volume
121pub_type
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