Local control of breast cancer with tumorectomy plus radiotherapy or radiotherapy alone.

Abstract:

:58 cases of breast cancer treated primarily by radiotherapy were evaluated to determine the optimum dose for local control. Of 36 patients with T1 + T2 lesions who had tumorectomy prior to radiotherapy, incomplete excision of tumor was demonstrated on microscopic examination in 18. The minimum tumor dose to the breast was 4,500 rads in 5 weeks. Treatment failed to control local tumor in only 2 (5%) and metastases in 1.26 (72%) remained disease-free for 2 to 9 years. Of the 22 patients with T3 + T4 lesions, treatment failed to control both local tumor and metastases in 12 (54%); in those who received 6,000 rads or less in 6 weeks, treatment failed to control any of these lesions. 4,500-5,500 rads controlled the tumor in 95% of those with NO + N1 disease, compared to only half of those with N2 + N3 tumors.

journal_name

Radiology

journal_title

Radiology

authors

Ghossein NA,Stacey P,Alpert RT,Ager PJ,Krishnaswamy V

doi

10.1148/121.2.455

subject

Has Abstract

pub_date

1976-11-01 00:00:00

pages

455-9

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

121

pub_type

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