Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals.

Abstract:

:The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV-positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Halstead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.

journal_name

Psychosomatics

journal_title

Psychosomatics

authors

Silberstein CH,O'Dowd MA,Schoenbaum EE,Friedland GH,Chartock P,Feiner C,McKegney FP

doi

10.1016/s0033-3182(93)71824-1

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

502-5

issue

6

eissn

0033-3182

issn

1545-7206

pii

S0033-3182(93)71824-1

journal_volume

34

pub_type

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