Abstract:
:The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV-positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Halstead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.
journal_name
Psychosomaticsjournal_title
Psychosomaticsauthors
Silberstein CH,O'Dowd MA,Schoenbaum EE,Friedland GH,Chartock P,Feiner C,McKegney FPdoi
10.1016/s0033-3182(93)71824-1subject
Has Abstractpub_date
1993-11-01 00:00:00pages
502-5issue
6eissn
0033-3182issn
1545-7206pii
S0033-3182(93)71824-1journal_volume
34pub_type
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