Abstract:
:In a 12-week placebo-controlled study of fluoxetine in the treatment of body dysmorphic disorder, the authors investigated change in psychosocial functioning and mental health-related quality of life in 60 subjects. The subjects were assessed with the LIFE-RIFT (a measure of impaired functioning), Social and Occupational Functioning Scale (SOFAS), and Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) before and after receiving fluoxetine or placebo. At baseline, the patients had impaired psychosocial functioning and markedly poor mental health-related quality of life. Compared to placebo, fluoxetine was associated with significantly greater improvement in LIFE-RIFT and SOFAS scores and with improvement on the mental health subscale of the SF-36 that approached significance. Decrease in the severity of body dysmorphic disorder, as measured by the Yale-Brown Obsessive Compulsive Scale Modified for Body Dysmorphic Disorder, was significantly correlated with improvement in functioning and quality of life.
journal_name
Psychosomaticsjournal_title
Psychosomaticsauthors
Phillips KA,Rasmussen SAdoi
10.1176/appi.psy.45.5.438subject
Has Abstractpub_date
2004-09-01 00:00:00pages
438-44issue
5eissn
0033-3182issn
1545-7206pii
S0033-3182(04)70159-0journal_volume
45pub_type
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