Abstract:
:In our earlier report on circulating immune complexes (CIC) from sera of patients with Hodgkin's disease (HD), we demonstrated disease-associated increase in the intensity of a 40kD (pl 5.6) polypeptide in the CIC. In extension of these investigations, we now report that the 40kD moiety exists in CIC as a complex with IgG, and that IgG isolated from such CIC samples from sera of patients with HD shows preferential reactivity with the typical large binucleate Reed-Sternberg (R-S) cells in the sections of disease-involved lymph nodes from HD patients.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Nerurkar AV,Advani SH,Gothoskar BPsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
87-91issue
2eissn
0028-2685issn
1338-4317journal_volume
40pub_type
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