Abstract:
:Herbicidal-mixtures have not been adequately studied in biological systems. Therefore, mixtures of three commonly-used herbicides were evaluated. Alachlor (AL), atrazine (AT), picloram (PI), AL+AT, AT+PI, PI+AL and AL+AT+PI, at 10 ppm (in drinking water) of each herbicide, were provided to mice for 30, as well as for 90, days ad libitum; these herbicides and mixtures, at 100 mg/kg (in corn oil) of each herbicide, were also given to additional groups of mice by oral intubation daily for 21 days. In the 30-day test, the spleen/body weight ratios on Day 31 with respect to the control were increased in the AT (53%) and AL+AT (44%) groups. Decreases in the body weights were noted in the treated groups after Day 31 during the 90-day test. Serum glutamic-pyruvic transaminase (SGPT), glutamic-oxalacetic transaminase (SGOT) and alkaline phosphatase activities with AL+AT+PI were elevated by 36-92% on Day 91; SGPT (34%) and SGOT (73%) activities were increased with AL. During the 21-day oral intubation study, the mouse body weights in the mixture groups were generally lower than the control (p < or = 0.05). The liver/body weight ratios were elevated in all groups (16-38%); the spleen/body weight ratio increased with PI (50%). The kidney/body weight ratios were high with PI+AL and AL+AT+PI (p < or = 0.05). Excluding AT, the pentobarbital-induced sleep was less (51-77%) in the herbicide-treated groups. Also, necrosis of individual and small groups of hepatocytes was noted with the mixtures.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Arch Environ Contam Toxicoljournal_title
Archives of environmental contamination and toxicologyauthors
Chaturvedi AKdoi
10.1007/BF01146160subject
Has Abstractpub_date
1993-05-01 00:00:00pages
449-54issue
4eissn
0090-4341issn
1432-0703journal_volume
24pub_type
杂志文章abstract::Bald eagles (Haliaeetus leucocephalus) nesting in the Apostle Islands National Lakeshore and along the Wisconsin shoreline of Lake Superior produced an average of 0.8 young/occupied nest and had an average nest success of 57% during 1983-1988, compared to 1.3 young/occupied nest and 77% nest success in inland Wisconsi...
journal_title:Archives of environmental contamination and toxicology
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doi:10.1007/BF01065326
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF01055559
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF01160293
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journal_title:Archives of environmental contamination and toxicology
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doi:10.1007/s00244-017-0409-6
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF01054986
更新日期:1990-05-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF02097772
更新日期:1977-01-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF01055143
更新日期:1979-01-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-005-0122-8
更新日期:2006-07-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
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journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-009-9380-1
更新日期:2010-04-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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更新日期:1995-05-01 00:00:00
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更新日期:2009-05-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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更新日期:2013-07-01 00:00:00
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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journal_title:Archives of environmental contamination and toxicology
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更新日期:2004-08-01 00:00:00
abstract::Chlorothalonil, a broad-spectrum nonsystemic foliar fungicide, is one of the most extensively used pesticide active ingredients on Prince Edward Island, Canada, for blight control on potatoes. In ambient air-sampling programs conducted in 1998 and 1999 and from 2002 to 2004, chlorothalonil was measured in 97% of air s...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
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更新日期:2012-02-01 00:00:00
abstract::Arsenic is accumulated by free-living small mammals, but there is little information on the resultant concentrations in different tissues other than liver and kidney. Such information is important because the severity of toxicological effects may be related to the amount of arsenic accumulated in specific organs, and ...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-004-0229-3
更新日期:2005-11-01 00:00:00
abstract::Occurrence of traditional (PBDEs) and novel (HBB, PBEB, DBDPE) brominated flame retardants, as well as the natural compounds of MeO-PBDEs, were studied in a shellfish species (Hexaplex trunculus) sampled from Bizerte Lagoon. PBDE and MeO-PBDE mean concentrations in murex soft tissues were 187 and 264 ng g-1 lw respect...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00