Regression of large pelvic desmoid tumor by tamoxifen and sulindac.

Abstract:

:A 54-year-old man was evaluated for symptoms of bladder outlet obstruction. Evaluation revealed a 10 by 9.8-cm tumor composed of bland, fibroblastic, poorly cellular material adjacent to the prostate. Administration of a course of antiestrogen (tamoxifen) and a nonsteroidal anti-inflammatory agent (sulindac) resulted in prompt relief of symptoms and a slow decrease in the size of the tumor as measured by computed tomography. After 54 months of therapy, the tumor was undetectable clinically and dramatically reduced in size as seen on computed tomography. Data on the natural history of desmoid tumors and the efficacy of various therapeutic strategies are reviewed.

journal_name

Urology

journal_title

Urology

authors

Izes JK,Zinman LN,Larsen CR

doi

10.1016/s0090-4295(96)00026-x

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

756-9

issue

5

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(96)00026-X

journal_volume

47

pub_type

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