Abstract:
:We examined the records of 82 patients with clinical Stage I nonseminomatous germ cell tumors of the testis who, after radical orchiectomy, were treated by surveillance at M.D. Anderson Cancer Center between October, 1981, and March, 1987. Our purpose was to determine whether or not patients with a low risk of relapse can be identified at the time of the initial staging evaluation. In 30 of 82 patients (Group 1), embryonal carcinoma constituted less than 80 percent of the tumor, no vessel invasion was present, and the preorchiectomy serum AFP level was less than 80 ng/dL. No relapses occurred in this group. Fifty-two patients (Group 2) had more than 80 percent embryonal carcinoma or vessel invasion or a serum AFP level higher than 80 ng/dL. Relapse occurred in 24 (46%) of these patients. The difference in the rate of relapse between patients in Group 1 and Group 2 was statistically significant (P less than 0.00001). A separate analysis of teratoma as a predictor of nonrelapse showed that the orchiectomy specimens of 30 of the 82 patients contained more than 50 percent teratoma. Only 1 relapse occurred among 25 patients with more than 50 percent teratoma and no vessel invasion. Our data show that there is a subgroup of patients with clinical Stage I nonseminomatous germ cell tumor who have a very low rate of relapse. We believe these patients can be effectively treated by surveillance and should be spared the morbidity of an unnecessary retroperitoneal lymph node dissection.
journal_name
Urologyjournal_title
Urologyauthors
Wishnow KI,Johnson DE,Swanson DA,Tenney DM,Babaian RJ,Dunphy CH,Ayala AG,Ro JY,von Eschenbach ACdoi
10.1016/0090-4295(89)90436-6subject
Has Abstractpub_date
1989-12-01 00:00:00pages
339-43issue
6eissn
0090-4295issn
1527-9995pii
0090-4295(89)90436-6journal_volume
34pub_type
杂志文章相关文献
UROLOGY文献大全abstract::Emphysematous pyelonephritis is a severe infection found almost exclusively in diabetics, characterized by the presence of gas within the renal parenchyma. The diagnosis is established radiographically. An additional case is added to the 52 cases reported in the literature; we believe this is the fifth reported case w...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(85)90332-2
更新日期:1985-03-01 00:00:00
abstract::Studies to detect ultrastructural changes in testicular tissues after a fifteen-minute exposure to ultrasonic waves were done in 10 men undergoing bilateral orchiectomies for prostatic carcinoma. Examination of Sertoli cells and germ cells in different stages of differentiation failed to reveal significant differences...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(87)90232-9
更新日期:1987-09-01 00:00:00
abstract::Recent advances in the understanding of the pathogenesis, behavior, and molecular biology of renal cell carcinoma (RCC) have paved the way for developments that may enhance early diagnosis, better predict prognosis, and improve survival. Reliable predictive factors are essential for the stratification of patients into...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2005.06.112
更新日期:2005-11-01 00:00:00
abstract::A patient with bilateral cryptorchidism and gynecomastia due to Leydig cell tumor involving the left intra-abdominal testis is described. Raised serum estrogen, low serum testosterone, and ultrasonic demonstration of a tumor in the left testis allowed the diagnosis to be suspected preoperatively. The relevant literatu...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(93)90546-m
更新日期:1993-12-01 00:00:00
abstract::Bladder reconstruction, either by augmentation or substitution enterocystoplasty, is a safe alternative to supravesical urinary diversion providing careful attention to preoperative selection, surgical technique, and postoperative review is observed. However, under the most optimal conditions an untoward outcome may o...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(92)90428-y
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:To evaluate oncological outcomes after radical cystectomy (RC) in patients with plasmacytoid urothelial carcinoma (UC) and to compare survival to that in patients with pure UC of the bladder. MATERIALS AND METHODS:We identified 46 patients with plasmacytoid UC and 972 with pure UC who were treated with RC be...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.09.053
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:To define the responses of stretched penile length (PL) to intramuscular testosterone enanthate (TE) treatment in prepubertal boys with hypospadias. METHODS:We examined 17 Japanese boys with hypospadias at 1.4 +/- 1.3 (mean +/- SD) years of age. Their PLs were 2.79 +/- 0.37 cm and -1.16 +/- 0.88 SD of the m...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.12.065
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:To determine whether the antiandrogen withdrawal syndrome occurs with the steroidal antiandrogen cyproterone acetate. METHODS:Cyproterone acetate was withheld in 12 patients with progressing androgen-independent metastatic prostate cancer. Eight patients had been receiving cyproterone acetate concomitant wi...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(98)00354-9
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVE:To report an alternative form of management of a persistent lymphocele that was unresponsive to percutaneous drainage and ethanol sclerotherapy. METHODS:Herein is described the technique of dilating the previously established percutaneous drainage tract to facilitate insertion of a flexible ureteroscope. Thr...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(94)90091-4
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVE:To evaluate in more detail the effectiveness of a new designed more efficient ultrasonic propulsion for large stones and specific stone compositions in a tissue phantom model. In the first clinical trial of noninvasive ultrasonic propulsion, urinary stones of unknown compositions and sizes up to 10 mm were su...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2017.09.013
更新日期:2018-01-01 00:00:00
abstract::Two cases of Kaposi sarcoma are presented. In each case the lesion had a bluish discoloration and was painless. Excision of lesions with wider margins was adequate therapy. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(85)90055-x
更新日期:1985-08-01 00:00:00
abstract::Laparoscopic nephrectomy in a giant hydronephrotic nonfunctioning kidney occupying the most of the abdomen is challenging task. To overcome the difficulty in laparoscopic dissection of such kidneys we described a technique "Pneumorenum," wherein the kidney is decompressed by suction through a 5 mm trocar inserted dire...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.11.044
更新日期:2020-12-06 00:00:00
abstract:OBJECTIVES:To evaluate the efficacy and complications of ileovesicostomy in patients with neurogenic bladder dysfunction. METHODS:Fifteen consecutive neurologically impaired patients (8 from multiple sclerosis, 4 from spinal cord injury, 3 from other causes) with complications of previous bladder management underwent ...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)00192-2
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:To study the expression of cannabinoid receptor 1 (CB1) in human urinary bladder hypersensitivity and overactivity disorders, and correlate changes with symptoms. Cannabinoid receptor agonists have been shown to modulate urinary bladder contractility and reduce pain after bladder inflammation; their clinical ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.12.051
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To report our experience with salvage high-intensity focused ultrasound (HIFU) in patients with local failure after brachytherapy for prostate cancer. PATIENTS AND METHODS:Whole-gland HIFU was administered to prospectively recruited patients with local histologic failure after brachytherapy at 2 institutions...
journal_title:Urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.urology.2014.06.054
更新日期:2014-11-01 00:00:00
abstract::Twenty-four patients with suspected renal injury were evaluated using high-dose intravenous pyelography, technetium-99m glucoheptonate radionuclide studies (RNS), and selective renal arteriography. Critical examination of these three diagnostic modalities reveal that RNS are extremely accurate in renal trauma evaluati...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(80)90422-7
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVES:This report is an update on the outcomes in the management of pathologic Stage C (T3N0) prostate cancer (CaP) with postoperative irradiation. METHODS:Between 1976 and 1994, 311 patients with pathologic Stage C CaP were treated with radical prostatectomy. Pathologic stage was as follows: C1, 60 patients (19%...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00011-4
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVES:The CD40 antigen is expressed by antigen-presenting cells, many kinds of epithelium, and carcinomas. As signaling through CD40 modulates the differentiation state of CD40-expressing cells, we wanted to investigate whether benign or malignant prostate epithelium expressed CD40. METHODS:Twenty-two paraffin-em...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)01005-0
更新日期:2001-03-01 00:00:00
abstract::Recently, a flexible, self-expanding, permanent endoprosthesis has been developed to maintain patency of stenotic arteries after balloon angioplasty. This device, known as the UroLume Wallstent, is now under active investigation in both Europe and the United States as a treatment for: (1) recurrent bulbar urethral str...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/0090-4295(93)90189-h
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVES:To clarify the age prevalence of female sexual dysfunction and the factors that contribute to the varying frequency of sexual intercourse and satisfaction with sexual life in Japanese women. METHODS:Of 8956 participants (median age 57 years, range 17 to 88) in a Japanese female cohort study, 5042 (56.3%) re...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2004.08.003
更新日期:2005-01-01 00:00:00
abstract::Lack of tumescence of the glans penis during normal penile erection may represent a handicap to sexual intercourse. The pharmacodynamic spongiosography for the evaluation of venous drainage of the corpus spongiosum is described, demonstrating a pathologic venous outflow. The patient was successfully treated by resecti...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(90)80151-c
更新日期:1990-04-01 00:00:00
abstract::CD20-negative diffuse large B-cell lymphoma (DLBCL) is a very uncommon neoplasm, and very rare unclassifiable cases that did not meet the criteria for well-established subtypes of CD20-negative DLBCLs have been reported. CD20-negative DLBCLs often present an aggressive clinical course with important chemoresistance an...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2018.04.019
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:To characterize the contemporary management of prostate cancer patients in large community practices. The optimal management of incident prostate cancer has changed in the last decades to include active surveillance for a large number of men. At the same time, many community practices have merged into larger ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2019.01.061
更新日期:2019-07-01 00:00:00
abstract::A urinary enzyme pattern and kidney tissue pattern were investigated simultaneously in 117 urologic patients. In contrast to all other renal disorders only the sixteen malignant tumors of the kidney showed a significant drop of gamma-GT in tumor tissue and urine. So far urinary enzymology has been used only as screeni...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(76)90553-7
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVES:Preoperative prostate-specific antigen (PSA) velocity (PSAV), the rate of PSA rise preceding diagnosis, predicts for relapse and cancer death after prostatectomy or radiotherapy. We studied the timing, cutoff levels, and method of calculation to better define its usefulness. METHODS:The rates of biochemical...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.01.019
更新日期:2007-04-01 00:00:00
abstract::In 1988 the KTP-532 laser was used to ablate a series of benign urethral strictures. Rather than using a single incision as in urethrotomy, strictures were treated with 360-degree contact photoradiation. Thirty-one male patients, average age 53.2 years, received thirty-seven treatments; 6 patients underwent a second l...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(92)90382-7
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVE:To systematically review prospective trials aimed at the role of restaging transurethral resection (reTUR) to define the group of patients with bladder cancer who would benefit. MATERIALS AND METHODS:A systematic review of the literature in accordance with the Preferred Reporting Items for Systematic Reviews...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2014.06.005
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To assess the association between Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) score, the Decipher score, and histologic grade of carcinoma in biopsy tissue among low- to intermediate-risk prostate cancer patients. METHODS:MRI-ultrasound targeted biopsy of regions of interest and concurre...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2018.12.001
更新日期:2019-03-01 00:00:00
abstract::A premature newborn male required intensive care and prolonged antibiotic therapy for respiratory distress. Acute renal failure developed from bilateral obstructive candida pyelonephritis complicating systemic Candida albicans infection. Necropsy also revealed organizing subarachnoid hematoma and granulomatous candida...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(83)90171-1
更新日期:1983-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the role of Her2/neu as a molecular marker predictive of the treatment response to bicalutamide in prostate cancer (PCa). METHODS:Four PCa cell lines with graded Her2/neu expression levels and 63 primary tumor cultures derived from men with PCa and selected according to Her2/neu tumor levels wer...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.01.018
更新日期:2009-08-01 00:00:00