Abstract:
BACKGROUND:Pityriasis lichenoides (PL) is a self-limiting papulosquamous disease that may persist for years and is associated with a high relapse rate. To date, few comparative studies have investigated the efficacy of narrowband ultraviolet B (NB-UVB) phototherapy and other therapies in the treatment of PL. OBJECTIVES:The present study retrospectively compared the clinical efficacies of NB-UVB phototherapy, systemic therapy, and a combination of NB-UVB and systemic medication in the treatment of PL. METHODS:Seventy patients diagnosed with PL were enrolled in this study. They were divided into three subgroups: the NB-UVB treatment group; the systemic treatment group; and the combination treatment group. Therapeutic efficacy was evaluated according to whether the subjects demonstrated a complete response (> 90% improvement in skin lesions), partial response (50-90% improvement), or no response (< 50% improvement) to treatment. RESULTS:A 91.9% complete response rate was achieved in the NB-UVB group, whereas only 69.2 and 80.0% of patients achieved a complete response in the systemic and combination treatment groups, respectively; these differences were not statistically significant. The mean treatment periods were 8.3, 5.3, and 7.9 weeks in the NB-UVB, systemic, and combination treatment groups, respectively; these differences were also not significant. CONCLUSIONS:Monotherapy using NB-UVB is effective in achieving a complete response in the treatment of PL and thus eliminates the need for concurrent systemic medication.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Park JM,Jwa SW,Song M,Kim HS,Chin HW,Ko HC,Kim MB,Kim BSdoi
10.1111/j.1365-4632.2012.05814.xsubject
Has Abstractpub_date
2013-08-01 00:00:00pages
1013-8issue
8eissn
0011-9059issn
1365-4632journal_volume
52pub_type
杂志文章abstract:BACKGROUND:The cosmetic importance of hair as a unique structure of the scalp is immense, such that once the loss of hair becomes an issue for a child, parents, in most cases, project their own concerns, often expressed as guilt. The clinical presentation of hair loss and scalp disorders in children varies widely, ofte...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03457.x
更新日期:2007-10-01 00:00:00
abstract::The mechanism of infection in South American blastomycosis is discussed, and the probability of a mild or asymptomatic form of the disease, regressing spontaneously with subsequent immunity, in persons living in endemic areas. Primary lesions in the oral mucosa or in the skin have not been convincingly shown to occur ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1975.tb01428.x
更新日期:1975-03-01 00:00:00
abstract:BACKGROUND:This study reports the comorbidity of lifetime psychiatric disorders in children and adolescents with alopecia areata (AA) in a child and adolescent psychiatry clinical sample. METHODS:Fourteen patients with AA were interviewed using the Diagnostic and Statistical Manual of Mental Disorders-Fourth edition (...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03743.x
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Phototherapy is already established as an effective mode of therapy in vitiligo. An evidence-based study was carried out of the effect of narrow-band (311 nm) ultraviolet-B (NB-UV-B) radiation in 66 surgically treated patients with recalcitrant vitiligo in whom autologous mini-punch grafting was deployed. M...
journal_title:International journal of dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1365-4632.2005.02697.x
更新日期:2006-06-01 00:00:00
abstract::The present work compared the clinical efficacy of topically applied 1 alpha,25-dihydroxyvitamin D3 (1 alpha,25-(OH)2D3) in 16 cases with psoriasis vulgaris, 5 with ichthyosis vulgaris and 8 with X-linked ichthyosis. Sixty-nine percent of the psoriatic cases responded to 1 alpha,25-(OH)2D3 therapy, whereas no ichthyot...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1991.tb05885.x
更新日期:1991-01-01 00:00:00
abstract::A 36-year-old Asian man with von Hippel-Lindau syndrome was referred to the dermatology clinic in January 2005 with stiff fingers and ankles of 3 months' duration. He had undergone bilateral nephrectomy for renal squamous cell carcinoma in 2002 and had started hemodialysis. Multiple cerebellar hemangiomata were resect...
journal_title:International journal of dermatology
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doi:10.1111/j.1365-4632.2008.03655.x
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abstract:BACKGROUND:Chronic plaque psoriasis has a profound impact on a patient's daily life. To understand the effects of psoriasis treatments, it is essential to assess the patient's experience of symptoms and how they impact their daily life. The goal of this study was to develop and establish the content validity of a new p...
journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Neutrophils play a critical role in host defense against a variety of microbial pathogens. There is much information to suggest a role for vitamin C in the physiology of neutrophils. Thus, the effects of vitamin C treatment were studied in a patient with a history of recurrent furunculosis who showed altered...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb02780.x
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND AND DESIGN:Scorpion stings are a serious problem in Khuzestan, a southwestern province of Iran. In around 5 years, 36,463 patients with scorpion stings have been seen. Most of the patients had no cutaneous findings, but a small group of patients developed various local and generalized skin manifestations. Pa...
journal_title:International journal of dermatology
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更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Coccidiodomycosis is a systemic infection caused by Coccidioides immitis, a dimorphic fungus endemic in the south of the USA and the north of Mexico. The disease usually affects the lungs. Primary cutaneous infection is extremely rare. We present a report of a patient with primary cutaneous infection located...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
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更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The rate of human immunodeficiency virus (HIV) infection in women of reproductive age has increased dramatically in the last decade. The effects of pregnancy on the prevalence of cutaneous diseases in this group is unclear. OBJECTIVES:To compare the prevalence of cutaneous diseases in healthy pregnant women...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2003.01776.x
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abstract::A 5-year study of 668 patients with genital lesions revealed that teenagers and those in the age group of 20 to 40 are most vunerable. The poor, the uneducated and unmarried persons are at high risk. Chancroid and syphilis are the majority of cases. Inguinal bubo, herpes pregenitalis, condylomata acuminata, erosive ba...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:
更新日期:1976-10-01 00:00:00
abstract::In a survey of clinical trials concerning the efficacy of short-contact therapy with anthralin in psoriasis vulgaris, focusing principally on methodologic issues, twenty-four papers published between January 1982 and December 1989, in English, French, and Italian, were selected. Nine of 24 papers reported on more than...
journal_title:International journal of dermatology
pub_type: 杂志文章,meta分析
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更新日期:1992-02-01 00:00:00
abstract::Omalizumab is a recombinant humanized monoclonal antibody targeting the high-affinity Fc receptor of IgE, registered for the treatment of chronic spontaneous urticaria and severe allergic asthma. We present a case series of nine patients with atopic dermatitis (AD) treated off-label with omalizumab and a systematic re...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
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更新日期:2017-01-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.12161
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Phenytoin (5,5 diphenylhydantoin), a widely-used anticonvulsant, has been employed both topically and systemically in the treatment of some dermatological disorders. Immunological and non-immunological defects suggests that phenytoin could be therapeutically effective for vitiligo repigmentation. AIM OF STU...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2012.05551.x
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abstract:BACKGROUND:Antitumor necrosis factor (anti-TNF) agents are a well-established treatment for various medical conditions, including psoriasis and psoriatic arthritis. However, anti-TNF agents may themselves induce psoriasis in some patients. METHODS:The authors report two cases of patients with severe and refractory inf...
journal_title:International journal of dermatology
pub_type: 杂志文章
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journal_title:International journal of dermatology
pub_type: 杂志文章
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journal_title:International journal of dermatology
pub_type: 杂志文章
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journal_title:International journal of dermatology
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doi:10.1046/j.1365-4362.1999.00586.x
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journal_title:International journal of dermatology
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pub_type: 杂志文章
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journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2001.01159.x
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:In this study, we have investigated the chemotherapeutic potential of a purple violet pigment (PVP), which was isolated from a previously undescribed Antarctic Janthinobacterium sp. (Ant5-2), against murine UV-induced 2237 fibrosarcoma and B16F10 melanoma cells. METHODS:The 2237, B16F10, C50, and NIH3T3 cel...
journal_title:International journal of dermatology
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doi:10.1111/j.1365-4632.2010.04825.x
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
pub_type: 杂志文章
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abstract::Based on a study of 400 patients (272 patients with herpes zoster and 128 with postzoster neuralgia), the subcutaneous injection of triamcinolone in saline is concluded to be a safe and effective measure for reducing pain. The acute eruption and symptoms of herpes zoster cleared in an average of less than four days. P...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1981.tb05299.x
更新日期:1981-01-01 00:00:00
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journal_title:International journal of dermatology
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更新日期:2016-08-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章
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