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Improving docosahexaenoic acid productivity of Schizochytrium sp. by a two-stage AEMR/shake mixed culture mode.

Abstract：

:In this work, an aeration-enhanced membrane reactor (AEMR) was built to control dissolved oxygen in Schizochytrium sp. broth. The effect of culture modes, i.e. single shake and AEMR mode, on the docosahexaenoic acid (DHA) productivity of Schizochytrium sp. was investigated. Experimental results showed that the biomass production in the AEMR mode was higher than that in the single shake mode, while the final DHA productivity in single shake mode was higher than that in the AEMR mode. A two-stage mixed culture mode was proposed, in which Schizochytrium sp. was cultured in AEMR mode at a flow rate of 0.2 L min(-1) for 60 h to first increase biomass production, and then shifted to shake mode to improve DHA productivity. Compared to the single shake mode, the DHA productivity in mixed mode costed 40% less culture time and the DHA productivity at 96 h exhibited a relative increase of 60%.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Zhang L,Zhao H,Lai Y,Wu J,Chen H

doi

10.1016/j.biortech.2013.05.072

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

719-22

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(13)00832-8

journal_volume

142

pub_type

杂志文章

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