Meta-analysis: the impact of oral anti-viral agents on the incidence of hepatocellular carcinoma in chronic hepatitis B.

abstract：BACKGROUND:Some patients requiring acid suppression may be unable to take oral medications. AIM:To compare the gastric acid inhibition effects of lansoprazole 30 mg administered either intravenous or orally in erosive oesophagitis patients. METHODS:The study included 87 Helicobacter pylori-negative patients with eros...

journal_title：Alimentary pharmacology & therapeutics

authors： Kovacs TO,Lee CQ,Chiu YL,Pilmer BL,Metz DC

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:Anti-TNF agents are now widely used in Crohn's disease (CD), and in ulcerative colitis (UC). AIM:To review the safety profile of anti-TNF agents in all patients treated with infliximab in Edinburgh from 1999 to 2007. METHODS:Complete data were available on 202/207 patients comprising 157 CD, 42 UC and thre...

journal_title：Alimentary pharmacology & therapeutics

authors： Lees CW,Ali AI,Thompson AI,Ho GT,Forsythe RO,Marquez L,Cochrane CJ,Aitken S,Fennell J,Rogers P,Shand AG,Penman ID,Palmer KR,Wilson DC,Arnott ID,Satsangi J

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) genotype 6 is common among patients from Southeast Asia and the surrounding regions, where HCV prevalence is also high. HCV genotype 6 has great genetic diversity and different response to antiviral therapy compared with the more commonly known genotype 1. AIM:Our goal was to provide...

journal_title：Alimentary pharmacology & therapeutics

authors： Chao DT,Abe K,Nguyen MH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection may persist after both first- and second-line current treatments. AIM:To assess the efficacy of a third-line, culture-guided treatment approach for the eradication of H. pylori. METHODS:Patterns of resistance were analysed in H. pylori isolates from 94 consecutive patients in ...

journal_title：Alimentary pharmacology & therapeutics

authors： Cammarota G,Martino A,Pirozzi G,Cianci R,Branca G,Nista EC,Cazzato A,Cannizzaro O,Miele L,Grieco A,Gasbarrini A,Gasbarrini G

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:In patients with pruritus of cholestasis, response to conventional drug treatment may be unsatisfactory. Activation of 5-hydroxytryptamine receptors on dermal sensory nerve-endings plays a role in the perception of pruritus. The 5-hydroxytryptamine(3) receptor antagonist, ondansetron, has been used in the tr...

journal_title：Alimentary pharmacology & therapeutics

authors： O'Donohue JW,Pereira SP,Ashdown AC,Haigh CG,Wilkinson JR,Williams R

更新日期：2005-04-15 00:00:00

abstract：BACKGROUND:Allergy and immune dysregulation may have a role in the pathophysiology of recurrent abdominal pain of functional origin, but previous studies of allergy-related diseases and abdominal pain have contradictory results. AIM:To examine the association between allergy-related diseases or sensitisation during ch...

journal_title：Alimentary pharmacology & therapeutics

authors： Olén O,Neuman Å,Koopmann B,Ludvigsson JF,Ballardini N,Westman M,Melén E,Kull I,Simrén M,Bergström A

更新日期：2014-12-01 00:00:00

abstract：:Twenty-four-hour intragastric acidity was measured in 10 patients with a past history of duodenal ulcer on the fourth day of dosing with placebo, and either 150 mg ranitidine given twice or four times daily. The order of the treatments was randomized and a double-blind design was employed. Ranitidine (150 mg) b.d. dec...

journal_title：Alimentary pharmacology & therapeutics

authors： Howden CW,Tsai HH,Reid JL

更新日期：1989-06-01 00:00:00

abstract：:There is general agreement that Helicobacter pylori eradication is indicated in all infected patients with duodenal ulcer disease and is probably indicated in all infected patients with gastric ulcer disease. However, translation of treatment recommendations into practice leads to some difficult clinical decisions. Th...

journal_title：Alimentary pharmacology & therapeutics

authors： Walsh JH

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Studies have shown that past alcohol consumption reduces response rates in patients with chronic hepatitis C treated with interferon monotherapy. AIM:To clarify the importance of alcohol consumption on response rates in patients undergoing treatment with pegylated interferon and ribavirin. METHODS:In a sin...

journal_title：Alimentary pharmacology & therapeutics

authors： Chang A,Skole K,Gautam M,Schmutz J,Black M,Thomas R,Horwitz B,Friedenberg FK

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND:Proton pump inhibitor (PPI) use may alter the gut microbiome and increase the risk of cholangitis. However, the association of PPI use with the risk of incident cholangitis has not been evaluated. AIM:To evaluate whether PPI use was associated with a higher risk of cholangitis. METHODS:This cohort study in...

journal_title：Alimentary pharmacology & therapeutics

authors： Min YW,Kang D,Shin JY,Kang M,Park JK,Lee KH,Lee JK,Lee KT,Rhee PL,Kim JJ,Guallar E,Cho J,Lee H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:In the past decade, a number of population-based studies have examined the prevalence of coeliac disease in individuals with type 1 diabetes but prevalences have differed considerably. AIM:To examine the prevalence of coeliac disease in individuals with type 1 diabetes. METHODS:A systematic review of Engli...

journal_title：Alimentary pharmacology & therapeutics

authors： Elfström P,Sundström J,Ludvigsson JF

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Fibroblast growth factors play an important role in (patho)physiological processes such as wound healing and tissue repair. We previously showed that basic fibroblast growth factor is actively involved in inflammatory bowel disease processes. In the present retrospective study, we assessed whether serum basi...

journal_title：Alimentary pharmacology & therapeutics

authors： Gao Q,Hogezand RA,Lamers CB,Verspaget HW

更新日期：2004-09-01 00:00:00

abstract：AIM:To assess the pathophysiology and treatment of neurogenic dysphagia. METHODS:46 patients with brain damage, 46 with neurodegenerative diseases and eight healthy volunteers were studied by videofluoroscopy while swallowing 3-20 mL liquid (20.4 mPa s), nectar (274.4 mPa s) and pudding (3931.2 mPa s) boluses. RESULT...

journal_title：Alimentary pharmacology & therapeutics

authors： Clavé P,de Kraa M,Arreola V,Girvent M,Farré R,Palomera E,Serra-Prat M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The use of healthcare resources for the management of constipation is not well-known. AIM:To analyse healthcare seeking for constipation, defined by three different criteria, and its related factors and to assess the frequency of use of laxatives, suppositories and enemas for the treatment of constipation. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Gálvez C,Garrigues V,Ortiz V,Ponce M,Nos P,Ponce J

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:Patients with coronary artery disease (CAD) treated with stents require dual antiplatelet therapy (DAPT). For cirrhotics, who often have varices and coagulopathy, it is not clear if the risk of gastrointestinal bleeding (GIB) should preclude use of DAPT. AIM:To compare GIB and mortality rates in cirrhotics ...

journal_title：Alimentary pharmacology & therapeutics

authors： Krill T,Brown G,Weideman RA,Cipher DJ,Spechler SJ,Brilakis E,Feagins LA

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Non-ulcer dyspepsia is predominantly a self-managed condition, although it accounts for a significant number of general practitioner consultations and hospital referrals. Herbal medicinal products are often used for the relief of dyspeptic symptoms. AIMS:: To critically assess the evidence for and against h...

journal_title：Alimentary pharmacology & therapeutics

authors： Thompson Coon J,Ernst E

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Randomized, placebo controlled trials are used to assess the efficacy of therapies for Crohn's disease. The placebo response and remission rates vary among studies. AIM:To analyse how the placebo response and remission rates in Crohn's trials have changed over time in the era of parenteral biologic therapie...

journal_title：Alimentary pharmacology & therapeutics

authors： Gallahan WC,Case D,Bloomfeld RS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Early differentiation of malignant from benign bile duct obstruction is of utmost importance. AIM:To identify biochemical and clinical predictors for malignancy in patients with bile duct obstruction, and establish a predictive model by combining pre-treatment patient characteristics. A web-based applicatio...

journal_title：Alimentary pharmacology & therapeutics

authors： Meister T,Uphoff MA,Heinecke A,Domagk D,Kunsch S,Lindhorst A,Ellenrieder V,Heinzow HS

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Barrett's oesophagus is the major risk factor for oesophageal adenocarcinoma. 5-Aminlevulinic acid-induced photodynamic therapy and argon plasma coagulation have been shown to be effective for ablating Barrett's oesophagus, but a comparative trial of these two modalities has not been reported. AIMS:To compa...

journal_title：Alimentary pharmacology & therapeutics

authors： Kelty CJ,Ackroyd R,Brown NJ,Stephenson TJ,Stoddard CJ,Reed MW

更新日期：2004-12-01 00:00:00

abstract：:The United Network for Organ Sharing database revealed that over the last 4-5 years, an average of 1800 patients were removed from the cadaveric waiting list annually because of patients' death and an additional 400-500 were removed from the list because of the severity of their illnesses. The pre-transplant evaluatio...

journal_title：Alimentary pharmacology & therapeutics

authors： Pham PT,Pham PC,Rastogi A,Wilkinson AH

更新日期：2005-04-15 00:00:00

abstract：BACKGROUND:The therapeutic effect of enteral nutrition in Crohn's disease (CD) and the epidemiological associations between diet and inflammatory bowel disease (IBD) implicate diet in IBD causation. There is little evidence, however, to support specific dietary changes and patients often receive contradictory advice. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Richman E,Rhodes JM

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors have been found to be effective in numerous studies in patients with peptic ulcer disease, particularly associated with Helicobacter pylori and gastro-oesophogeal reflux disorders. Optimal healing rates of antisecretory therapy for peptic acid disease is dependent upon the degree and d...

journal_title：Alimentary pharmacology & therapeutics

authors： Blum RA,Hunt RH,Kidd SL,Shi H,Jennings DE,Greski-Rose PA

更新日期：1998-04-01 00:00:00

abstract：:An analysis carried out in 1994 by the WHO International Agency for Research on Cancer (IARC) resulted in Helicobacter pylori being designated as a Group 1 carcinogen and thus clearly having an association with the development of gastric cancer. In the case of H. pylori, the evaluation was made solely on the basis of ...

journal_title：Alimentary pharmacology & therapeutics

authors： Asaka M,Kudo M,Kato M,Sugiyama T,Takeda H

更新日期：1998-02-01 00:00:00

abstract：:This review focuses on the methodology and interpretation of drug trials in peptic ulcer disease. The problems of planning and conduct that are discussed include the ethics of using placebo, eligibility criteria, estimations of sample size, stopping rules, randomization, blinding, and efficacy criteria, that is, ulcer...

journal_title：Alimentary pharmacology & therapeutics

authors： Lauritsen K,Rask-Madsen J

更新日期：1987-04-01 00:00:00

abstract：:Endoscopic procedures generate bacteraemia to different degrees. Under certain conditions, most notably valvular heart disease, clinically significant infections may occur. A large body of literature has grown around recommendations for antibiotic prophylaxis to prevent procedure-related infections. Most of this liter...

journal_title：Alimentary pharmacology & therapeutics

authors： Schembre D,Bjorkman DJ

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Recently a new 'all in one' single capsule with the three components of bismuth-based triple therapy became available in trials for treating Helicobacter pylori. AIM:To investigate the efficacy and tolerability of this new capsule when combined with lansoprazole. METHODS:A total of 66 consecutive infected ...

journal_title：Alimentary pharmacology & therapeutics

authors： De Boer WA,Van Etten RJ,Van De Wouw BA,Schneeberger PM,Van Oijen AH,Jansen JB

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Anti-TNFα biologics induce and maintain remission in inflammatory bowel disease (IBD). Also, they have been reported to induce or unmask idiopathic inflammatory demyelinating disease of the central nervous system (IIDD). AIM:To determine if anti-TNFα biologics increased the risk of IIDD in a large cohort of...

journal_title：Alimentary pharmacology & therapeutics

authors： De Felice KM,Novotna M,Enders FT,Faubion WA,Tremaine WJ,Kantarci OH,Raffals LE

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The combination of omeprazole and amoxycillin has demonstrated effectiveness with very few side-effects in the treatment of H. pylori infection, however cure rates have varied widely. The present study addresses the question as to the extent to which the cure rate of H. pylori infection depends on the size o...

journal_title：Alimentary pharmacology & therapeutics

authors： Miehlke S,Mannes GA,Lehn N,Hele C,Stolte M,Bayerdörffer E

更新日期：1997-04-01 00:00:00

abstract：:Colorectal cancer is a common cancer and common cause of death. The mortality rate from colorectal cancer can be reduced by identification and removal of cancer precursors, adenomas, or by detection of cancer at an earlier stage. Pilot screening programmes have demonstrated decreased colorectal cancer mortality; as a ...

journal_title：Alimentary pharmacology & therapeutics

authors： Nicholson FB,Barro JL,Atkin W,Lilford R,Patnick J,Williams CB,Pignone M,Steele R,Kamm MA

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Owing to the importance of early treatment, simple and reliable methods for monitoring inflammatory bowel disease (IBD) are needed. AIMS:To determine whether circulating microRNAs are reliable biomarkers for IBD monitoring. METHODS:Serum levels of 17 candidate microRNAs were measured by quantitative real-t...

journal_title：Alimentary pharmacology & therapeutics

authors： Chen P,Li Y,Li L,Yu Q,Chao K,Zhou G,Qiu Y,Feng R,Huang S,He Y,Chen B,Chen M,Zeng Z,Zhang S

更新日期：2019-03-01 00:00:00