Healthcare seeking for constipation: a population-based survey in the Mediterranean area of Spain.

Abstract:

BACKGROUND:The use of healthcare resources for the management of constipation is not well-known. AIM:To analyse healthcare seeking for constipation, defined by three different criteria, and its related factors and to assess the frequency of use of laxatives, suppositories and enemas for the treatment of constipation. METHODS:A cross-sectional study in the general community. A questionnaire comprising 21-items was developed and delivered by mail to a random sample of 506 subjects aged 18-65 years, and belonging to a Spanish population. RESULTS:Seeking of health care was high in the sample (16%) and was similar for all definitions of constipation (over 40% of constipated subjects). It was associated with female gender, a higher educational level and two symptoms, such as prolonged defecation and abdominal pain. A 14% of the sample used laxatives, and about a 25% of constipated subjects used laxatives at least once a week. Utilization was more frequent in women, with no differences by age group. CONCLUSIONS:Chronic constipation is a problem that causes an important consumption of resources in our setting, derived from laxative use and the seeking of medical help to combat the problem. The use of these resources is higher in women.

journal_name

Aliment Pharmacol Ther

authors

Gálvez C,Garrigues V,Ortiz V,Ponce M,Nos P,Ponce J

doi

10.1111/j.1365-2036.2006.02981.x

subject

Has Abstract

pub_date

2006-07-15 00:00:00

pages

421-8

issue

2

eissn

0269-2813

issn

1365-2036

pii

APT2981

journal_volume

24

pub_type

杂志文章
  • Nutritional management of patients with acute pancreatitis: a Dutch observational multicentre study.

    abstract:BACKGROUND:Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. AIM:To evaluate the nutritional management of patients with AP in a Dutch cohort ...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1365-2036.2008.03814.x

    authors: Spanier BW,Mathus-Vliegen EM,Tuynman HA,Van der Hulst RW,Dijkgraaf MG,Bruno MJ,EARL Study Group.

    更新日期:2008-11-01 00:00:00

  • Colonoscopy-controlled intra-individual comparisons to screen relevant neoplasia: faecal immunochemical test vs. guaiac-based faecal occult blood test.

    abstract:BACKGROUND:Guaiac-based faecal occult blood tests (g-FOBTs) are most commonly used in colorectal cancer (CRC) screening programmes. Faecal immunochemical tests (FITs) are thought to be superior. AIM:To compare performance of a g-FOBT and a quantitative FIT for detection of CRCs and advanced adenomas in a colonoscopy-c...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1365-2036.2009.04184.x

    authors: Oort FA,Terhaar Sive Droste JS,Van Der Hulst RW,Van Heukelem HA,Loffeld RJ,Wesdorp IC,Van Wanrooij RL,De Baaij L,Mutsaers ER,van der Reijt S,Coupe VM,Berkhof J,Bouman AA,Meijer GA,Mulder CJ

    更新日期:2010-02-01 00:00:00

  • Endoscopic ablation of Barrett's oesophagus: a randomized-controlled trial of photodynamic therapy vs. argon plasma coagulation.

    abstract:BACKGROUND:Barrett's oesophagus is the major risk factor for oesophageal adenocarcinoma. 5-Aminlevulinic acid-induced photodynamic therapy and argon plasma coagulation have been shown to be effective for ablating Barrett's oesophagus, but a comparative trial of these two modalities has not been reported. AIMS:To compa...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2036.2004.02277.x

    authors: Kelty CJ,Ackroyd R,Brown NJ,Stephenson TJ,Stoddard CJ,Reed MW

    更新日期:2004-12-01 00:00:00

  • Antibiotic prophylaxis prior to endoscopic retrograde cholangiopancreatography in patients with obstructive jaundice: is it worth the cost?

    abstract:BACKGROUND:There are few published data concerning the economic impact of antibiotic prophylaxis prior to endoscopic retrograde cholangiopancreatography in the setting of biliary obstruction. AIM:To perform decision analysis to determine the costs of prophylaxis in patients undergoing endoscopic retrograde cholangiopa...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2036.2002.01209.x

    authors: Thompson BF,Arguedas MR,Wilcox CM

    更新日期:2002-04-01 00:00:00

  • Omeprazole, clarithromycin and furazolidone for the eradication of Helicobacter pylori in patients with duodenal ulcer.

    abstract:AIM:To evaluate the efficacy of omeprazole plus clarithromycin and furazolidone in Helicobacter pylori eradication and duodenal ulcer healing in Brazilian patients. METHODS:Forty H. pylori-positive patients with duodenal ulcer were randomized to receive 20 mg omeprazole o.m. or b.d. for 1 month plus 500 mg clarithromy...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2036.1999.00653.x

    authors: Dani R,Queiroz DM,Dias MG,Franco JM,Magalhães LC,Mendes GS,Moreira LS,De Castro LP,Toppa NH,Rocha GA,Cabral MM,Salles PG

    更新日期:1999-12-01 00:00:00

  • Randomised clinical trial: ghrelin agonist TZP-101 relieves gastroparesis associated with severe nausea and vomiting--randomised clinical study subset data.

    abstract:BACKGROUND:Limited therapeutic options exist for severe gastroparesis, where severe nausea and vomiting can lead to weight loss, dehydration and malnutrition due to inadequate caloric and fluid intake. TZP-101 (ulimorelin) is a ghrelin receptor agonist that accelerates gastric emptying and improves upper gastrointestin...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1365-2036.2010.04567.x

    authors: Wo JM,Ejskjaer N,Hellström PM,Malik RA,Pezzullo JC,Shaughnessy L,Charlton P,Kosutic G,McCallum RW

    更新日期:2011-03-01 00:00:00

  • Review article: treatment algorithms to maximize remission and minimize corticosteroid dependence in patients with inflammatory bowel disease.

    abstract:BACKGROUND:Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the intestine, which frequently require surgery for complications or failure of medical therapy. AIM:To seek evidence and provide direction for clinicians on optimal strategies to enable steroid free remission in inflammat...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2036.2008.03753.x

    authors: Panaccione R,Rutgeerts P,Sandborn WJ,Feagan B,Schreiber S,Ghosh S

    更新日期:2008-09-15 00:00:00

  • Survival after treatment with curative intent for hepatocellular carcinoma among patients with vs without non-alcoholic fatty liver disease.

    abstract:BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is expected to become a leading aetiology of hepatocellular carcinoma (HCC)-related mortality in the United States. HCC treatments with curative intent (OLT, orthotopic liver transplantation; resection; RFA, radiofrequency ablation) can improve survival in carefully ...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/apt.14342

    authors: Wong CR,Njei B,Nguyen MH,Nguyen A,Lim JK

    更新日期:2017-12-01 00:00:00

  • The use of pictograms improves symptom evaluation by patients with functional dyspepsia.

    abstract:BACKGROUND:No validated patient-reported outcome (PRO) measure exists for functional dyspepsia (FD) assessment. Verbal descriptions of different upper abdominal symptoms may be poorly distinguishable to patients. AIM:To investigate whether understanding of FD symptoms is enhanced by pictograms symbolising the nature o...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/apt.12855

    authors: Tack J,Carbone F,Holvoet L,Vanheel H,Vanuytsel T,Vandenberghe A

    更新日期:2014-09-01 00:00:00

  • Systematic review: combination therapies for treatment-naïve chronic hepatitis B.

    abstract:BACKGROUND:There is a renewed interest in use of combination therapies in treatment-naïve chronic hepatitis B (CHB) because of limitations of monotherapies. AIM:To discuss the current status of combination therapies in treatment-naïve CHB. METHODS:PubMed search was done using 'combination', 'sequential' and 'chronic ...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2036.2008.03695.x

    authors: Kumar M,Sarin SK

    更新日期:2008-06-01 00:00:00

  • Systematic review: microscopic colitis.

    abstract:BACKGROUND:Collagenous and lymphocytic colitis are fairly common causes of chronic non-bloody diarrhoea, especially in elderly female. AIM:To present a systematic review of microscopic colitis. METHODS:A PubMed search using the MeSH terms microscopic colitis, collagenous colitis, lymphocytic colitis and chronic diarr...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2036.2006.02913.x

    authors: Nyhlin N,Bohr J,Eriksson S,Tysk C

    更新日期:2006-06-01 00:00:00

  • Review: clinical trials in peptic ulcer disease--problems of methodology and interpretation.

    abstract::This review focuses on the methodology and interpretation of drug trials in peptic ulcer disease. The problems of planning and conduct that are discussed include the ethics of using placebo, eligibility criteria, estimations of sample size, stopping rules, randomization, blinding, and efficacy criteria, that is, ulcer...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2036.1987.tb00610.x

    authors: Lauritsen K,Rask-Madsen J

    更新日期:1987-04-01 00:00:00

  • No increase in risk of fracture, malignancy or mortality in dermatitis herpetiformis: a cohort study.

    abstract:BACKGROUND:Dermatitis herpetiformis forms part of the same spectrum of gluten-sensitive disorders as coeliac disease yet may have different risks of morbidity and mortality. AIMS:To quantify the risks of fracture, malignancy and mortality in people with dermatitis herpetiformis compared with the general population. M...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2036.2008.03660.x

    authors: Lewis NR,Logan RF,Hubbard RB,West J

    更新日期:2008-06-01 00:00:00

  • Systematic review: the hepatotoxicity of non-steroidal anti-inflammatory drugs.

    abstract:BACKGROUND:Non-steroidal anti-inflammatory drugs have been implicated in reports of liver injury. However, the precise risk of non-steroidal anti-inflammatory drugs for this rare complication is unknown. AIM:To review systematically the published literature of population-based epidemiological studies reporting the inc...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2036.2004.02092.x

    authors: Rubenstein JH,Laine L

    更新日期:2004-08-15 00:00:00

  • Triple vs. quadruple therapy for treating Helicobacter pylori infection: a meta-analysis.

    abstract:BACKGROUND:Triple therapy (proton pump inhibitor, clarithromycin and amoxicillin or an imidazole) is the first-line treatment for Helicobacter pylori infection. However, the effectiveness of triple therapy is decreasing due to the increase in antibiotic resistance. Quadruple therapy (proton pump inhibitor, tetracycline...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,meta分析

    doi:10.1046/j.1365-2036.2003.01566.x

    authors: Gené E,Calvet X,Azagra R,Gisbert JP

    更新日期:2003-05-01 00:00:00

  • Fluorescence in situ hybridization vs. epsilometer test for detection of clarithromycin-susceptible and clarithromycin-resistant Helicobacter pylori strains in gastric biopsies from children.

    abstract:AIM:To compare the results of culture and epsilometer test with fluorescence in situ hybridization for the detection of Helicobacter pylori and the presence of clarithromycin-susceptible and clarithromycin-resistant strains in antral biopsies from children. METHODS:Antral biopsies from 149 unselected children were inv...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2036.2002.01382.x

    authors: Feydt-Schmidt A,Rüssmann H,Lehn N,Fischer A,Antoni I,Störk D,Koletzko S

    更新日期:2002-12-01 00:00:00

  • Characteristics of patients with irritable bowel syndrome recruited from three sources: implications for clinical trials.

    abstract:BACKGROUND:Variation in the characteristics of irritable bowel syndrome patients recruited for clinical trials from different sources could affect their response and the generalizability of trial results. AIM:To describe and compare the characteristics of three different groups of irritable bowel syndrome patients rec...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2036.2001.01010.x

    authors: Longstreth GF,Hawkey CJ,Mayer EA,Jones RH,Naesdal J,Wilson IK,Peacock RA,Wiklund IK

    更新日期:2001-07-01 00:00:00

  • The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury.

    abstract:BACKGROUND:Drug-induced liver injury may be immunologically mediated or metabolically induced. Peripheral eosinophilia and liver eosinophilia in suspected drug-induced liver injury generally supports the role of drug aetiology. AIM:To assess the importance of eosinophilia and hepatic necrosis on outcome in patients wi...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2036.2007.03330.x

    authors: Björnsson E,Kalaitzakis E,Olsson R

    更新日期:2007-06-15 00:00:00

  • The organ extraction and splanchnic haemodynamic effects of octreotide in cirrhotic patients.

    abstract:BACKGROUND:Intravenous octreotide is an established treatment of oesophageal variceal haemorrhage in the cirrhotic patient. AIM:To examine the organ extraction and splanchnic haemodynamic effects of octreotide in cirrhotic patients with portal hypertension. METHODS:Thirteen patients with cirrhosis had hepatic venous ...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2036.1998.00353.x

    authors: Ottesen LH,Flyvbjerg A,Møller S,Bendtsen F

    更新日期:1998-07-01 00:00:00

  • Novel score for prediction of malignant bile duct obstruction based on biochemical and clinical markers.

    abstract:BACKGROUND:Early differentiation of malignant from benign bile duct obstruction is of utmost importance. AIM:To identify biochemical and clinical predictors for malignancy in patients with bile duct obstruction, and establish a predictive model by combining pre-treatment patient characteristics. A web-based applicatio...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/apt.13152

    authors: Meister T,Uphoff MA,Heinecke A,Domagk D,Kunsch S,Lindhorst A,Ellenrieder V,Heinzow HS

    更新日期:2015-05-01 00:00:00

  • Systematic review: the effects of proton pump inhibitors on the microbiome of the digestive tract-evidence from next-generation sequencing studies.

    abstract:BACKGROUND:Proton pump inhibitors (PPI) are widely used to treat acid-related disorders of the upper gastrointestinal tract. However, large observational studies have raised concerns about PPI-associated adverse events. In recent years, data from next-generation sequencing studies suggested that PPIs affect the composi...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/apt.15604

    authors: Macke L,Schulz C,Koletzko L,Malfertheiner P

    更新日期:2020-03-01 00:00:00

  • Helicobacter DNA in bile: correlation with hepato-biliary diseases.

    abstract:BACKGROUND:Helicobacter has been identified in isolated cases of hepato-biliary diseases, but its role in the pathogenesis of these conditions remains unclear. AIM:To determine whether Helicobacter could be detected in bile obtained at endoscopic retrograde cholangiopancreatography, and to evaluate the prevalence of t...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2036.2003.01424.x

    authors: Fallone CA,Tran S,Semret M,Discepola F,Behr M,Barkun AN

    更新日期:2003-02-01 00:00:00

  • Review article: metoclopramide and tardive dyskinesia.

    abstract:BACKGROUND:Metoclopramide is a dopamine receptor antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In 2009, the FDA issued a black box warning regarding long-term or high-dose use of this medication because of the risk of developing tardive dyskinesia. A...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2036.2009.04189.x

    authors: Rao AS,Camilleri M

    更新日期:2010-01-01 00:00:00

  • A double-blind comparison of balsalazide, 6.75 g, and sulfasalazine, 3 g, as sole therapy in the management of ulcerative colitis.

    abstract:BACKGROUND:Sulfasalazine is accepted therapy for active ulcerative colitis, but side-effects and intolerance are common. Balsalazide is an azo-bonded pro-drug which also releases 5-aminosalicylic acid into the colon, but uses an inert carrier molecule. AIM:To compare the safety and efficacy of sul- fasalazine, 3 g, wi...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1046/j.1365-2036.2002.01151.x

    authors: Mansfield JC,Giaffer MH,Cann PA,McKenna D,Thornton PC,Holdsworth CD

    更新日期:2002-01-01 00:00:00

  • The association between markers of liver injury and clinical outcomes in patients with COVID-19 in Wuhan.

    abstract:BACKGROUND:The outbreak of coronavirus disease 2019 (COVID-19) is a critical challenge for public health. The effect of COVID-19 on liver injury has not been fully established. AIMS:To evaluate the dynamic changes in liver function and the relationship between liver damage and prognosis in patients with COVID-19. MET...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/apt.15962

    authors: Huang H,Chen S,Li H,Zhou XL,Dai Y,Wu J,Zhang J,Shao L,Yan R,Wang M,Wang J,Tu Y,Ge M

    更新日期:2020-09-01 00:00:00

  • Factors associated with villus atrophy in symptomatic coeliac disease patients on a gluten-free diet.

    abstract:BACKGROUND:Duodenal injury persists in some coeliac disease patients despite gluten-free diet, and is associated with adverse outcomes. AIM:To determine the prevalence and clinical risk factors for persistent villus atrophy among symptomatic coeliac disease patients. METHODS:A nested cross-sectional analysis was perf...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/apt.13988

    authors: Mahadev S,Murray JA,Wu TT,Chandan VS,Torbenson MS,Kelly CP,Maki M,Green PH,Adelman D,Lebwohl B

    更新日期:2017-04-01 00:00:00

  • The effect of portal hypertension on indomethacin-induced small intestinal ulceration in the rat.

    abstract::The purpose of this study was to determine whether portal hypertension potentiates intestinal ulceration induced by indomethacin. Portal hypertension was produced in male Sprague-Dawley rats by two-staged ligation of the portal vein. Sham-operated rats were used as controls. The rats were given 20 mg/kg of indomethaci...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2036.1991.tb00004.x

    authors: Jonas GM,Erickson RA,Chung K

    更新日期:1991-02-01 00:00:00

  • Nitrofurantoin quadruple therapy for Helicobacter pylori infection: effect of metronidazole resistance.

    abstract:BACKGROUND:Antibiotic resistance has increasingly been recognized as the major cause of treatment failure for Helicobacter pylori infection. New therapies for patients with metronidazole- or clarithromycin-resistant H. pylori are needed. AIM:To investigate the role of nitrofurantoin quadruple therapy for the treatment...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2036.2001.00945.x

    authors: Graham DY,Saeed MA,Hoffman J,El-Zimaity HM,Kwon DH,Osato MS

    更新日期:2001-04-01 00:00:00

  • Prescription of nonselective NSAIDs, coxibs and gastroprotective agents in the era of rofecoxib withdrawal - a 617,400-patient study.

    abstract:BACKGROUND:Gastroprotective strategies are recommended for nonsteroidal anti-inflammatory drug (NSAID) users at risk of upper gastrointestinal (UGI) complications. AIM:To compare the use of gastroprotective strategies in NSAID users in three countries, and the subsequent impact of rofecoxib withdrawal. METHODS:We con...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章

    doi:10.1111/apt.12028

    authors: Valkhoff VE,van Soest EM,Masclee GM,de Bie S,Mazzaglia G,Molokhia M,Kuipers EJ,Sturkenboom MC

    更新日期:2012-10-01 00:00:00

  • Systematic review: health-related quality of life in children and adults with eosinophilic oesophagitis-instruments for measurement and determinant factors.

    abstract:BACKGROUND:Several measures have been used to assess the health-related quality of life (HRQoL) of patients with eosinophilic oesophagitis (EoE). AIMS:To systematically review these HRQoL measures, to appraise measurement properties of specific instruments and to evaluate determinant factors influencing HRQoL in paedi...

    journal_title:Alimentary pharmacology & therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/apt.14194

    authors: Lucendo AJ,Arias-González L,Molina-Infante J,Arias Á

    更新日期:2017-08-01 00:00:00