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Idiopathic constipation in childhood is associated with thickening of the internal anal sphincter.

Abstract：

:This study was undertaken to search for a rational basis for the use of anal dilatation and internal sphincterotomy as the treatment for chronic intractable constipation in children. Sixteen children, age 5 months to 13 years, who had constipation resistant to conservative treatment were compared with 39 age-matched controls. History and current symptoms were assessed using a standard questionnaire. Internal and external and sphincter morphology was assessed on clinical examination and by anal endosonography, using a 10-MHz rotating endoprobe to provide accurate measurement of the various components of the anal canal. The control group showed a linear correlation between the thickness of the internal anal sphincter and both age and weight, increasing from 0.4 mm in infancy to 0.9 mm in adolescence. Children who had constipation displayed significant thickening of the internal sphincter (range, 0.5 to 1.9 mm, P = .005) which was independent of the length of the history (P = .103). There was no difference in the morphology of the external anal sphincters between the groups. The finding of a hypertrophied internal anal sphincter could provide a rational basis for anal dilatation and internal sphincterotomy as treatment for idiopathic constipation.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Hosie GP,Spitz L

doi

10.1016/s0022-3468(97)90395-x

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

1041-3; discussion 1043-4

issue

7

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(97)90395-X

journal_volume

32

pub_type

杂志文章

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