Abstract:
:Diethylstilbestrol diphosphate (DES-P) has shown effective symptomatic relief in patients with metastatic carcinoma of the prostate. Although there is little known about its role in soft tissue metastasis, our experience in 3 patients with advanced carcinoma of the prostate infiltrating the trigone and ureterovesical junction revealed significant improvement of hydronephrosis. All patients failed to respond to conventional doses of stilbestrol. Diethylstilbestrol diphosphate is recommended in the treatment of advanced carcinoma of the prostate with soft tissue metastasis. It is safe and effective, and the tumor responses outweigh the side effects of the drug. The mechanism of action of this compound is discussed.
journal_name
Urologyjournal_title
Urologyauthors
Susan LP,Roth RB,Adkins WCdoi
10.1016/0090-4295(76)90084-4subject
Has Abstractpub_date
1976-06-01 00:00:00pages
598-601issue
6eissn
0090-4295issn
1527-9995journal_volume
7pub_type
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