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Uropharmacology: v. choline esters and other parasympathomimetic drugs.

Abstract：

:Various parasympathomimetic drugs are discussed, including the choline esters, bethanechol, carbachol, methacholine chloride, and furtrethonium. Other cholinomimetic agents include muscarine, muscarone, arecholine, and pilocarpine. Anticholinesterase agents inhibit or inactivate acetylcholinesterase enzyme and thus result in a prolonged stimulation of cholinergic receptors by endogenous ACh. Bethanechol is the most widely used parasympathomimetic drug in the United States. Its action is mainly muscarinic with activity largely confined to the urinary bladder and to a lesser degree the gastrointestinal tract. It can be administered only subcutaneously or orally, and adequate dosage is necessary for a successful response.

journal_name

Urology

journal_title

Urology

authors

Finkbeiner AE,Bissada NK,Welch LT

doi

10.1016/0090-4295(77)90052-8

subject

Has Abstract

pub_date

1977-07-01 00:00:00

pages

83-9

issue

1

eissn

0090-4295

issn

1527-9995

journal_volume

10

pub_type

杂志文章,评审

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