Tumor-associated tissue inflammatory reaction and eosinophilia in primary superficial bladder cancer.

Abstract:

:In a retrospective study the data of 428 patients with primary superficial transitional cell carcinoma of the bladder were evaluated. The histologic slides were reviewed for presence of a tumor-associated tissue inflammatory reaction, especially tumor-associated eosinophilia. Tumor-associated cell infiltration was found in 23.1 percent and tumor-associated eosinophilia in 2.1 percent. Tumor-associated cell infiltration was associated with less recurrences (p = 0.01). Tumor progression rate was not significantly influenced by tumor-associated cell infiltration. Tumor-related death rate was lower in the group with tumor-associated cell infiltrate (p = 0.50). Using the Cox regression model carcinoma in situ of the tumor margin, tumor-associated cell infiltrate, and grade of differentiation appeared to be important factors in the prognosis for survival.

journal_name

Urology

journal_title

Urology

authors

Flamm J

doi

10.1016/0090-4295(92)90524-z

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

180-5

issue

2

eissn

0090-4295

issn

1527-9995

pii

0090-4295(92)90524-Z

journal_volume

40

pub_type

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