Effect of ocular perfusion pressure on retinal function in the rabbit.

Abstract:

:The electroretinogram (ERG) vs perfusion pressure relation was studied in anesthetized rabbits during mechanically induced changes in mean arterial pressure (MAP). After 1 hr of dark adaptation, ERGs were obtained at perfusion pressures from 10 to 95 mmHg with each pressure held for 30-60 sec, and at three levels from 15 to 75 mmHg with each pressure held for 5 min. The slopes of the b-wave amplitude vs perfusion pressure data were not significantly different from zero during either the brief or longer manipulations of perfusion pressure. However, the b-wave was nearly extinguished 5 min after death. The results indicate that the rabbit ERG is maintained over a wide range of perfusion pressure.

journal_name

Vision Res

journal_title

Vision research

authors

Harrison JM,Kiel JW,Smith S

doi

10.1016/s0042-6989(97)00044-8

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

2339-47

issue

17

eissn

0042-6989

issn

1878-5646

pii

S0042-6989(97)00044-8

journal_volume

37

pub_type

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