Measurement properties of the Clinical Risk Index for Babies--reliabilty, validity beyond the first 12 hours, and responsiveness over 7 days.

abstract：OBJECTIVE:To determine the ability of somatosensory evoked potentials (SEP) compared with clinical findings to monitor and predict recovery in patients suffering from closed head injury with predominantly diffuse axonal injury (DAI). DESIGN:Prospective cohort study. SETTING:Neurologic intensive care unit (ICU) of a u...

journal_title：Critical care medicine

authors： Claassen J,Hansen HC

更新日期：2001-03-01 00:00:00

abstract：:PEEP is the most important therapeutic intervention in the management of acute respiratory failure. Transitory PEEP disconnection to perform clinically relevant maneuvers is often necessary, but its effect upon PaO2 and physiological shunt in patients requiring high-level PEEP is not clear from the literature. Nine ad...

journal_title：Critical care medicine

authors： De Campo T,Civetta JM

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety of human albumin administered for therapeutic purposes. DESIGN:Retrospective compilation of spontaneously reported serious adverse events. SETTING:Records of serious adverse event reports received from 1990 through 1997 by nine major suppliers of therapeutic human albumin worldwide. ...

journal_title：Critical care medicine

authors： von Hoegen I,Waller C

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Trauma induces a complex immune response that requires a systems biology research approach. Here, we used a novel technology, mass cytometry by time-of-flight, to comprehensively characterize the multicellular response to trauma. DESIGN:Peripheral blood mononuclear cells samples were stained with a 38-marker...

journal_title：Critical care medicine

authors： Seshadri A,Brat GA,Yorkgitis BK,Keegan J,Dolan J,Salim A,Askari R,Lederer JA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Cognitive deficits after traumatic brain injury are a leading cause of disability worldwide, yet no effective pharmacologic treatments exist to improve cognition. Traumatic brain injury increases proinflammatory cytokines, which trigger excess function of α5 subunit-containing γ-aminobutyric acid type A rece...

journal_title：Critical care medicine

authors： Khodaei S,Avramescu S,Wang DS,Sheng H,Chan NK,Lecker I,Fernandez-Escobar A,Lei G,Dewar MB,Whissell PD,Baker AJ,Orser BA

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To investigate the interaction and involvement of hydrogen sulfide and transient receptor potential vanilloid type 1 in the pathogenesis of sepsis. Hydrogen sulfide has been demonstrated to be involved in many inflammatory states including sepsis. Its contribution in neurogenic inflammation has been suggested...

journal_title：Critical care medicine

authors： Ang SF,Moochhala SM,Bhatia M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Opioids are frequently used during mechanical ventilation for severe viral infection in infancy. Opioid receptors have immunomodulatory properties, but nothing is known about their antiviral effects. We therefore aimed to investigate the role of opioid receptors in virus-induced airway inflammation. PATIENTS...

journal_title：Critical care medicine

authors： Salimi V,Hennus MP,Mokhtari-Azad T,Shokri F,Janssen R,Hodemaekers HM,Rygiel TP,Coenjaerts FE,Meyaard L,Bont L

更新日期：2013-01-01 00:00:00

abstract：:Pulmonary artery wedge pressure (PAWP) will only reflect left atrial pressure (LAP) if continuity of fluid exists from the catheter tip to the left atrium. Either increased airway pressure or decreased hydrostatic pressure may lead to discontinuity of the fluid column and midinterpretation of PAWP. Simultaneous measur...

journal_title：Critical care medicine

authors： Kane PB,Askanazi J,Neville JF Jr,Mon RL,Hanson EL,Webb WR

更新日期：1978-01-01 00:00:00

abstract：PURPOSE:Periodic diagnostic tests and continuous and intermittent monitoring are integral to critical care medicine. The focus of this article is understanding the impact of existing diagnostic technology, as well as that of new diagnostic technology. DATA SYNTHESIS:We use literature about gastric tonometry to illustr...

journal_title：Critical care medicine

authors： Keenan SP,Guyatt GH,Sibbald WJ,Cook DJ,Heyland DK,Jaeschke RZ

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:To measure temporal trends in survival over time in people with severe coronavirus disease 2019 requiring critical care (high dependency unit or ICU) management, and to assess whether temporal variation in mortality was explained by changes in patient demographics and comorbidity burden over time. DESIGN:Re...

journal_title：Critical care medicine

authors： Dennis JM,McGovern AP,Vollmer SJ,Mateen BA

更新日期：2021-02-01 00:00:00

abstract：:During the control period in this study, small premature infants, 1500 g in birth weight, had insensible water loss (IWL) of 2.28 g/kg/hr (equivlaent to 54 ml/kg/day), which is considerably higher than in full term infants. Under phototherapy, there was a significant increase in IWL (3.14 g/kg/hr) associated with incr...

journal_title：Critical care medicine

authors： Yeh TF,Vidyasagar D,Pildes RS

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:To determine the feasibility of utilizing a scintigraphic technique to differentiate patients with adult respiratory distress syndrome due to sepsis syndrome from control volunteers and patients with congestive heart failure. Gamma scintigraphy was compared with chest roentgenograms to predict mortality rate ...

journal_title：Critical care medicine

authors： Byrne K,Tatum JL,Henry DA,Hirsch JI,Crossland M,Barnes T,Thompson JA,Young J,Sugerman HJ

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To compare silver-coated and uncoated central venous catheters regarding bacterial colonization. To assess the relative contribution of catheter hub and skin colonization to catheter tip colonization. DESIGN:Prospective, randomized clinical trial. SETTING:Intensive care unit in a university hospital. PATIE...

journal_title：Critical care medicine

authors： Bach A,Eberhardt H,Frick A,Schmidt H,Böttiger BW,Martin E

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:Within minutes of reperfusing ischemic cardiomyocytes, oxidant stress dramatically increases and is associated with postresuscitation injury. Because mitochondria produce deleterious oxidants and useful metabolic substrates, utilization of electron transport chain inhibitors against reperfusion injury, though...

journal_title：Critical care medicine

authors： Anderson TC,Li CQ,Shao ZH,Hoang T,Chan KC,Hamann KJ,Becker LB,Vanden Hoek TL

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To determine daily amino acid and total protein losses in patients with acute renal failure receiving total parenteral nutrition (TPN) during treatment by continuous arteriovenous hemofiltration with hemodialysis (CAVHD). DESIGN:Prospective, nonrandomized study. SETTING:Patients in the ICU of a regional nep...

journal_title：Critical care medicine

authors： Davies SP,Reaveley DA,Brown EA,Kox WJ

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:Our intent was to evolve a prognosticator that would predict the likelihood that an electrical shock would restore a perfusing rhythm. Such a prognosticator was to be based on conventional electrocardiographic signals but without constraints caused by artifacts resulting from precordial compression. The adver...

journal_title：Critical care medicine

authors： Marn-Pernat A,Weil MH,Tang W,Pernat A,Bisera J

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:We investigated whether patients with chronic obstructive pulmonary disease could safely receive noninvasive ventilation outside of the ICU. DESIGN:Retrospective cohort study. SETTING:Twelve states with ICU utilization flag from the State Inpatient Database from 2014. PATIENTS:Patients greater than or equ...

journal_title：Critical care medicine

authors： Myers LC,Faridi MK,Currier P,Camargo CA Jr

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To examine the effects of mechanical ventilation with a tidal volume of 6 mL/kg compared with 12 mL/kg predicted body weight on hemodynamics, vasopressor use, fluid balance, diuretics, sedation, and neuromuscular blockade within 48 hrs in patients with acute lung injury and acute respiratory distress syndrome...

journal_title：Critical care medicine

authors： Cheng IW,Eisner MD,Thompson BT,Ware LB,Matthay MA,Acute Respiratory Distress Syndrome Network.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Septic shock represents the major cause of infection-associated mortality in the intensive care unit. The possibility that combination antibiotic therapy of bacterial septic shock improves outcome is controversial. Current guidelines do not recommend combination therapy except for the express purpose of broa...

journal_title：Critical care medicine

authors： Kumar A,Zarychanski R,Light B,Parrillo J,Maki D,Simon D,Laporta D,Lapinsky S,Ellis P,Mirzanejad Y,Martinka G,Keenan S,Wood G,Arabi Y,Feinstein D,Kumar A,Dodek P,Kravetsky L,Doucette S,Cooperative Antimicrobial Thera

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Sepsis is a frequent cause of admission, but incidence rates based on administrative data have previously produced large differences in estimates. The aim of the study was to estimate the incidence of community-acquired sepsis based on patients' symptoms and clinical findings at arrival to the hospital. DESI...

journal_title：Critical care medicine

authors： Henriksen DP,Laursen CB,Jensen TG,Hallas J,Pedersen C,Lassen AT

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To determine whether a continuous intravenous infusion of pentoxifylline, a methylxanthine derivative, alters the serum cytokine concentrations and/or hemodynamic measurements in patients with septic shock. DESIGN:A prospective, randomized, double-blind, placebo-controlled study. SETTING:Medical intensive c...

journal_title：Critical care medicine

authors： Zeni F,Pain P,Vindimian M,Gay JP,Gery P,Bertrand M,Page Y,Page D,Vermesch R,Bertrand JC

更新日期：1996-02-01 00:00:00

abstract：:A total of 2711 pulmonary artery wedge pressure (WP) measurement attempts were made prospectively from WP recordings in 44 (30 men) critically ill patients, using 77 flow-directed catheters. Of these, 322 (12%) failed to yield a WP measurement, and 521 (18%) were associated with technical problems. One half of these t...

journal_title：Critical care medicine

authors： Morris AH,Chapman RH,Gardner RM

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVES:Guidelines recommend offering family members of critically ill patients the option to attend interdisciplinary team rounds as a way to improve communication and satisfaction. Uncertainty remains around the benefits and risks. DESIGN:We conducted an observational study to describe family participation in ICU...

journal_title：Critical care medicine

authors： Au SS,Roze des Ordons AL,Parsons Leigh J,Soo A,Guienguere S,Bagshaw SM,Stelfox HT

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To study the effects of high-dose epinephrine, compared with standard-dose epinephrine, on the dynamics of superficial cortical cerebral blood flow as well as global cerebral oxygenation during experimental cardiopulmonary resuscitation. We hypothesized that high-dose epinephrine might be unable to improve ce...

journal_title：Critical care medicine

authors： Gedeborg R,Silander HC,Ronne-Engström E,Rubertsson S,Wiklund L

更新日期：2000-05-01 00:00:00

abstract：:Simple insertion of a nasogastric (NG) tube was successful in only 52 of 100 anesthetized intubated patients. After the larynx was manually pulled forward, the NG tube was successfully inserted in 33 patients. In the remaining 15 patients, the NG tube was inserted only with the aid of a finger or a laryngoscope used w...

journal_title：Critical care medicine

authors： Perel A,Ya'ari Y,Pizov R

更新日期：1985-03-01 00:00:00

abstract：:Vecuronium's short half-life and minimal cardiopulmonary side-effects make it a suitable drug for continuous infusion. Vecuronium is used frequently in critically ill patients to increase their total compliance and to minimize the adverse effects of mechanical ventilation. This crossover, prospective study evaluates t...

journal_title：Critical care medicine

authors： Eldadah MK,Newth CJ

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:To review the history and development of critical care nurses, the supply and demand issues related to critical care nursing, critical care nursing's contribution to patient outcomes, and recommendations to ensure a steady and strong workforce. DATA SOURCE AND SELECTION:Information presented in this article ...

journal_title：Critical care medicine

authors： Robnett MK

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Pulmonary air embolism, causing vessel obstruction and primary or secondary reactions of blood, can lead to acute lung injury. In addition, nitric oxide has been known to play a key role in various causes of lung injury. In this study we employed the isolated rat lung model to investigate the effects of l-arg...

journal_title：Critical care medicine

authors： Chu SJ,Lee TY,Yan HC,Lin SH,Li MH

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To determine the risk factors for development of severe hypoglycemia (defined as glucose <40 mg/dL) in critically ill patients and define the outcomes of this complication. DESIGN:Retrospective database review, including a case-control analysis that matched each patient with severe hypoglycemia with three co...

journal_title：Critical care medicine

authors： Krinsley JS,Grover A

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are devastating disorders of overwhelming pulmonary inflammation and hypoxemia, resulting in high morbidity and mortality. AIM:To provide the clinician with a summary of the literature on the epidemiology, diagnosi...

journal_title：Critical care medicine

authors： Randolph AG

更新日期：2009-08-01 00:00:00