Abstract：
BACKGROUND:Cell adhesion in the limbal region is of outstanding importance for the regeneration of the corneal epithelium and for repair mechanisms after antiglaucomatous fistulating surgery. In the basement membranes cell adhesion is largely modified by the extracellular matrix protein laminin. The aim of our study was to establish the immunohistochemical pattern of the different laminin-isoforms and subunits in the basal membrane of the limbal conjunctiva and episcleral vessels. MATERIAL AND METHOD:For immunohistochemistry five normal human donor eyes were included; we used antibodies against the laminin heterotrimers 1 and 2, against the laminin subunits alpha 2, beta 1, beta 2, gamma 1, gamma 2 and against the laminin-associated protein nidogen. RESULTS:The basement membrane of the limbal conjunctiva reveals immunoreactivity against all used antibodies. The subconjunctival and episcleral vessels showed no staining for the laminin subunit gamma 2, but for all other used antibodies. CONCLUSION:The basement membrane of the limbal and conjunctival epithelium as well as the basement membrane of subconjunctival and episcleral vessels express a broad spectrum of laminin variants. This diversity emphasizes functional specialization of the limbal region, although the exact importance of the laminin variants is still unknown.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Dietlein TS,Jacobi PC,Paulsson M,Smyth N,Krieglstein GKdoi
10.1055/s-2008-1035120subject
Has Abstractpub_date
1997-09-01 00:00:00pages
188-91issue
3eissn
0023-2165issn
1439-3999journal_volume
211pub_type
杂志文章abstract：:A report on 70 cases of retraction syndrome (Stilling-Türk-Duane). The patients presented with typical symptoms: severe limitation of abduction, slight limitation of adduction and convergence, which is always accompanied by retraction of the globe, narrowing of the palpebral fissure, vertical deviation and elevated in...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1055309
更新日期：1981-02-01 00:00:00
abstract：BACKGROUND:The aim of this study was to assess the significance of different clinical appearances of the vitreoretinal interface in the surgical management of acute postoperative endophthalmitis. PATIENTS AND METHODS:22 patients underwent vitrectomy and were divided intraoperatively in 3 groups according to the degree...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0028-1109286
更新日期：2009-04-01 00:00:00
abstract：:In 21 patients with macular hole and retinal detachment a macular buckling procedure was performed including diathermic or cryogenic coagulation. An absorbable fibrin sponge (Fibrospum) was used as a new buckling material, which needs not to be sutured to the sclera at the posterior pole. In comparison to other proced...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1977-08-01 00:00:00
abstract：:A 36-years aged woman suffering from migraine used Ergosanol special-suppositories. An edema of the retina with star figure appeared in both eyes with only a few months distance. After putting away that drug visual acuity restituted completely in spite of a partial neuritic atrophy of the optic nerve in the first suff...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：BACKGROUND:Little is known about how the expression of Ephrin type-A receptor 2 (EphA2) influences cell-cell adhesion, migration, angiogenesis, and the formation of vasculogenic mimicry (VM) channels in uveal melanomas or how this may be related to the rate of metastasis. MATERIAL AND METHODS:Paraffin embedded section...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0041-110956
更新日期：2016-03-01 00:00:00
abstract：:We present two further cases of choroiditis geographica. One of them we were able to follow up for two years. This allowed us to observe from the beginning the eye which was not at first involved. Weeks before the first lesions were visible, alterations of the EOG appeared. In the other case both eyes were already inv...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:Rapid movement (vibration) of a movable scissor blade against a stationary blade at alternating current frequency (50 Hz) provides considerable improvement of cutting power and decreases distortion and crushing of the tissue. The article describes vibrational scissors for cataract surgery. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1975-04-01 00:00:00
abstract：BACKGROUND:Photorefractive keratectomy (PRK) is an accepted procedure to correct myopia in Germany. The purpose of this study was to evaluate photoastigmatic refractive keratectomy (PARK) for myopic astigmatism. MATERIAL AND METHODS:PARK using the VISX 20/20 excimer laser was performed in 50 eyes of 36 patients (25 fe...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1034713
更新日期：1999-11-01 00:00:00
abstract：:From 126 patients with ocular hypertension and/or primary open-angle glaucoma, those (n = 18) who had an untreated intraocular pressure of at least 25 mm Hg or a cup/disk ratio of at least 0.8 were selected for this study. The course of the disease was followed by means of photos of the disk and visual field examinati...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1050763
更新日期：1986-08-01 00:00:00
abstract：:Report on a 69-year-old woman with a choroidal and a large peribulbar tumor. A scan ultrasonography of the peribulbar mass revealed a homogeneous structure of the lymphoma/sarcoma/pseudo-tumor type. Histological examination disclosed a reactive lymphoid hyperplasia without "Dutcher bodies", and consistent with a benig...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057457
更新日期：1980-02-01 00:00:00
abstract：BACKGROUND:The aim of the study was to find out if pupillographic assessment of the visual field by means of pupil campimetry can identify glaucomatous visual field defects and as such be used for glaucoma screening purposes. PATIENTS AND METHODS:20 patients with open angle glaucoma and 30 healthy persons were examine...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0032-1314985
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to report results, effectiveness and safety of implanting a negative collagen/HEMA copolymer posterior chamber phakic intraocular lens in moderate to highly myopic eyes. MATERIAL AND METHODS:23 eyes from 12 patients with a mean preoperative spherical equivalent refraction of - ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2002-30666
更新日期：2002-04-01 00:00:00
abstract：:The developments concern methods of application and therapeutic agents. Regarding drug aplication Ocusert has to be mentioned: inserted in the cul de sac of the eye once a week it releases a low concentration of a substance continuously and with a constant rate. For acetazolamid (Diamox) it has been shown, that in lon...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1977-02-01 00:00:00
abstract：BACKGROUND:In spite of the worldwide declining number of syphilis cases, there has been stable rate of syphilis infections in Switzerland from 2006 - 2008. In the year 2008 672 case were reported. Uveitis is the most common ocular finding in syphilis. It occurs in 2.5 %-5 % of all cases. HISTORY AND SIGNS:Six patients...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-0031-1273229
更新日期：2011-04-01 00:00:00
abstract：:Hereditary optic nerve disorders are rare. For ophthalmologists, Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are of particular relevance. LHON and ADOA are diseases of the retinal ganglion cells and are caused by mitchochondrial dysfunction. LHON is based on mutations of the ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章,评审
doi：10.1055/a-0583-6290
更新日期：2018-06-01 00:00:00
abstract：:An objective procedure for assessing damage to corneal endothelium is described; it is based on photometrical determination of the dye toluidine blue absorbed by damaged cells. This inexpensive quick test is suitable both for preoperative assessment of grafts and for checking procedures for cornea conversation. The us...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1055013
更新日期：1982-01-01 00:00:00
abstract：:Elevated protein concentrations in the aqueous humor, without Tyndall phenomenon, were found in a case of Coats' Disease. In particular, proteins of smaller size were involved. The permeability of the retinal vessels was presumed to be impaired. The resulting increase in protein concentrations in the aqueous humor cou...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057404
更新日期：1980-01-01 00:00:00
abstract：:No significant differences could be determined postoperatively between trabeculectomy and goniotrepanation. However, cases of flattened anterior chambers and choroidal detachments were less frequent after goniotrepanation than after trabeculectomy. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057716
更新日期：1980-12-01 00:00:00
abstract：BACKGROUND:The development of binocular diplopia after cataract surgery is a serious complication. The present retrospective study aims to improve our understanding of this phenomenon and its prevention. PATIENTS AND METHODS:A series of 11 patients with binocular diplopia after cataract surgery under local retrobulbar...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 临床试验,杂志文章
doi：10.1055/s-2006-926572
更新日期：2006-05-01 00:00:00
abstract：:By means of fluorescein angiography extensive defects in the pigmented epithelium found in choroideremia can be shown to be present in the first ten years of life. The degeneration of the vessels of the choroid and the functional damage to the retina do not seem to take place until later. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：:Immunocytochemical examination of a subretinal membrane removed during vitrectomy from a patient suffering from Coats' disease revealed macrophages, fibronectin, and vimentin. Vimentin is considered to be a marker of mesenchymal cells. Fibronectin may represent a guide rail and scaffold for the cellular organization o...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1050247
更新日期：1988-08-01 00:00:00
abstract：BACKGROUND:We report on an eight-year-old boy, who was presented in our clinic because of head turn. The cause of the tortecollis (ocular or general) in this case was and still cannot be explained. Only by applying extensive prism adaptation tests it was possible to prove the ocular character of the head turn. CASE RE...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1027477
更新日期：2008-08-01 00:00:00
abstract：:Visual acuity can be assessed by different strategies. The constant-stimulus-, the stair-case-, the Best-PEST-strategies, and the EN ISO 8596 are discussed. In cases of presumed psychogenic visual impairment and malingering it can be useful to modify these strategies striving for a determination of the (minimum) visua...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2004-812893
更新日期：2004-07-01 00:00:00
abstract：:Recognizing congenital syphilis in pediatric patients is of utmost importance with regard to therapy. The case of a 5-year-old girl with salt and pepper fundus demonstrates the importance of a thorough family history which led towards the diagnosis of congenital syphilis. This paper stresses the importance of family h...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1045820
更新日期：1992-05-01 00:00:00
abstract：:The author describes the genuine indications for the preventive treatment of retinal detachment. He was above all guided by the minute observations of the eye fundus of two eyes with the Goldmann-glass. The author's long experience and his auto-observation of the retinal detachment operation and of preventive treatmen...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1977-06-01 00:00:00
abstract：:Mycotic Septicaemia (especially with the Candida species) is not an uncommon hazard of hospitalized patients, especially those on intravenous hyperalimentation. Two such patients with endogenous mycotic bilateral endophthalmitis are presented. In spite of typical ocular symptoms diagnosis was delayed. Two further unil...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1976-03-01 00:00:00
abstract：:The effect of topical administration of Buphenine was studied in a group of aphakic patients (53 eyes). The action of the drug was paradoxical: it induced an increase, often remarkable, in intraocular pressure in more than 70% of the eyes thus treated. The cause of the elevated IOP is discussed. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：10.1055/s-2008-1057566
更新日期：1980-05-01 00:00:00
abstract：:During a trabeculectomy it is possible to interfere with the boundary between the iris and the ciliary body-that is with the iridociliary suture. The author describes some special features of this region which can be recognized through the operating microscope, with allusions to some aspects of optical microscopy. ...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
abstract：:The authors report on the possibilities for examination of the stereoscopic vision at 2 or 4 meters by the phase-difference-haploscope. Besides a gross-qualitative test, methods of estmating realdepth acuity are described. There is a great variability of test-conditions for special scientific problems. During the rout...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：:The relevance of fungal contamination of soft contact lenses is demonstrated by own clinical observations in 25 cases. It can be shown by surface-microscopical, histological and mycological analysis, that various fungi can not only grow on the surface of HEMA-lenses, but can also invade the material. The efficacy of c...
journal_title：Klinische Monatsblatter fur Augenheilkunde
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
