[Bile duct carcinoma in an adenoma in the anastomotic area after hepaticojejunostomy--a case report].

Abstract:

:Cholangiocarcinoma at the choledochoduodenal anastomosis site is a rare complication. Our 71-years-old female patient developed an adenocarcinoma 38 years after cholecystectomy and choledochoduodenal anastomosis. During the previous two years she suffered from recurrent episodes of cholangitis and jaundice. Multiple endoscopically obtained biopsies from a suspicious area at the anastomosis showed a tubular adenoma. With a CA19-9 of 2,429 U/l laparotomy was performed with radical removal of the choledochoduodenostomy and the extrahepatic bile ducts and reconstruction with hepaticojejunostomy. The histological examination revealed a poorly differentiated, partly solid, partly tubular adenocarcinoma of the choledochal duct with metastasis of the lymph nodes in the hepatoduodenal ligament. According to the UICC staging system the tumor was pT2, G3, pN1 classified as stage III. Two months later the patient developed a peritoneal carcinosis with a CA19-9 of 15,050 U/l and died. The development of cholangiocarcinoma may be caused by chronic cholangitis, which may arise from several diseases of the bile ducts like choledochal cysts, primary sclerosing cholangitis or reflux of duodenal contents like in choledochoduodenal anastomoses. Because of the heterogeneity inside the lesions a malignant lesion can only be excluded by histopathological examination of the whole tumor.

journal_name

Z Gastroenterol

authors

Schumacher G,Bechstein WO,Kling N,Lobeck H,Hintze R,Neuhaus P

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

1081-6

issue

12

eissn

0044-2771

issn

1439-7803

journal_volume

35

pub_type

杂志文章
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    authors: Dzirlo L,Haunold I,Lung S,Buchinger E,Müller-Knespel EM,Weiss P

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    pub_type: 杂志文章

    doi:

    authors: Klump B,Schneider GA,Fierlbeck G,Hoeft S,Gregor M,Porschen R

    更新日期:1997-06-01 00:00:00

  • [Value of minilaparoscopy in comparison with conventional laparoscopy in diagnosis of liver diseases--intermediate term results of a prospective, randomized study].

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

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    pub_type: 杂志文章

    doi:

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    更新日期:1980-10-01 00:00:00

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    pub_type: 杂志文章

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    authors: Schmidt-Wilcke HA,Wolfert W,Grundmann E

    更新日期:1977-08-01 00:00:00

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    doi:

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  • [Long-term collagenous sprue--remission with a gluten-free diet].

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    pub_type: 杂志文章

    doi:

    authors: Holtmann M,von Herbay A,Galle PR,Stremmel W

    更新日期:1999-12-01 00:00:00

  • [S3 Guideline on "sedation in gastrointestinal endoscopy": how much does the new guideline cost in everyday hospital work? A calculation model and analysis of implementation in 2011 among ALGK members].

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    doi:10.1055/s-0032-1313080

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    doi:10.1055/s-2007-963673

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  • [The fluorescein dilaurate serum test following metoclopramide and secretin stimulation for evaluating pancreatic function. Contribution to the diagnosis of chronic pancreatitis].

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    authors: Malfertheiner P,Büchler M,Müller A,Ditschuneit H

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  • [Determination of surgical status: stomach cancer].

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  • Different actions of neomychin and metronidazole on breath hydrogen (H2) exhalation.

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    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Lembcke B,Hönig M,Caspary WF

    更新日期:1980-03-01 00:00:00

  • Colonoscopy use in a country with a long-standing colorectal cancer screening programme: evidence from a large German survey.

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    doi:10.1055/s-0029-1245611

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    pub_type: 杂志文章

    doi:

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