Formation of autocrine loops in human cerebral meningioma tissue by leukemia inhibitor factor, interleukin-6, and oncostatin M: inhibition of meningioma cell growth in vitro by recombinant oncostatin M.

abstract：:OBJECTIVE Glioma is the most common form of brain tumor and has high lethality. The authors of this study aimed to elucidate the efficiency of preoperative inflammatory markers, including neutrophil/lymphocyte ratio (NLR), derived NLR (dNLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR), and progno...

journal_title：Journal of neurosurgery

authors： Zheng SH,Huang JL,Chen M,Wang BL,Ou QS,Huang SY

更新日期：2018-09-01 00:00:00

abstract：:Seven patients with spasticity of spinal cord origin have been maintained for up to 2 years with continuous spinal intrathecal infusion of baclofen. Prior to treatment, all of the patients had severe rigidity in their lower limbs and most had frequent and extensive spontaneous spasms, all of which greatly interfered w...

journal_title：Journal of neurosurgery

authors： Penn RD,Kroin JS

更新日期：1987-02-01 00:00:00

abstract：OBJECT:The authors characterized the clinical course of tectal plate lesions in a group of pediatric patients to identify the prognostic factors at presentation that predict progression, in an attempt to differentiate tectal hamartomas from tumors. METHODS:A retrospective review was conducted of the management of tect...

journal_title：Journal of neurosurgery

authors： Ternier J,Wray A,Puget S,Bodaert N,Zerah M,Sainte-Rose C

更新日期：2006-06-01 00:00:00

abstract：OBJECT:The use of focal brain cooling to eliminate epileptic discharges (EDs) has attracted increasing attention in the scientific community. In this study, the inhibitory effect of selective hippocampal cooling on experimental hippocampal seizures was investigated using a newly devised cooling system with a thermoelec...

journal_title：Journal of neurosurgery

authors： Tanaka N,Fujii M,Imoto H,Uchiyama J,Nakano K,Nomura S,Fujisawa H,Kunitsugu I,Saito T,Suzuki M

更新日期：2008-04-01 00:00:00

abstract：OBJECT:Quantitative and qualitative alterations in the epidermal growth factor receptor (EGFR) commonly occur in many cancers in humans, including malignant gliomas. The aim of the current study was to evaluate molecular and cellular effects of OSI-774, a novel EGFR tyrosine kinase inhibitor, on nine glioblastoma multi...

journal_title：Journal of neurosurgery

authors： Halatsch ME,Gehrke EE,Vougioukas VI,Bötefür IC,A-Borhani F,Efferth T,Gebhart E,Domhof S,Schmidt U,Buchfelder M

更新日期：2004-03-01 00:00:00

abstract：OBJECT:Intrasylvian hematoma (ISH) is a subtype of intracranial hematoma caused by aneurysmal rupture and often presents with a poor initial neurological grade; it is not well studied. The aim of this study was to elucidate outcomes of aneurysmal subarachnoid hemorrhage (SAH) with ISH. METHODS:Data for 97 patients wit...

journal_title：Journal of neurosurgery

authors： Fukuda H,Hayashi K,Moriya T,Nakashita S,Lo BW,Yamagata S

更新日期：2015-09-01 00:00:00

abstract：OBJECT:From the moment an intracranial aneurysm ruptures, cerebral blood flow is impaired, and this impairment mainly determines the outcome in patients who survive after the initial bleeding. The exact mechanism of impairment is unknown, but activation of coagulation and fibrinolysis correlate with clinical condition ...

journal_title：Journal of neurosurgery

authors： Siironen J,Juvela S,Varis J,Porras M,Poussa K,Ilveskero S,Hernesniemi J,Lassila R

更新日期：2003-12-01 00:00:00

abstract：:A rare case of a solitary schwannoma arising within the cerebellum is reported. The diagnosis was confirmed by electron microscopy and immunohistochemical staining. ...

journal_title：Journal of neurosurgery

authors： Sarkar C,Mehta VS,Roy S

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:Because of their complex topography, long courses, and small diameters, peripheral nerves are challenging structures for radiological diagnostics. However, imaging techniques in the area of peripheral nerve diseases have undergone unexpected development in recent decades. They include MRI and high-resolution ...

journal_title：Journal of neurosurgery

authors： Carolus AE,Lenz M,Hofmann M,Welp H,Schmieder K,Brenke C

更新日期：2019-04-26 00:00:00

abstract：:Saccular aneurysms arising at locations other than at arterial divisions are extremely rare. The authors describe eight such aneurysms that protruded from the dorsal wall of the internal carotid artery (ICA) and were unrelated to any arterial junction. Radical surgery was performed in all eight cases. The aneurysms we...

journal_title：Journal of neurosurgery

authors： Nakagawa F,Kobayashi S,Takemae T,Sugita K

更新日期：1986-09-01 00:00:00

abstract：:The diagnosis of CSF hypovolemia remains controversial. The primary diagnostic factor relies on confirmation of leakage of the CSF based on reduced spinal fluid pressure. Determining the specific leakage site is the most important issue for effective treatment but remains a difficult task. Although CT myelography, rad...

journal_title：Journal of neurosurgery

authors： Nakai E,Takemura M,Nonaka M,Kawanishi Y,Masahira N,Ueba T

更新日期：2016-02-01 00:00:00

abstract：:An abscess was removed from the left occipital region in a 73-year-old woman with no previous history of tuberculosis. The patient later died from aspiration bronchopneumonia. Autopsy revealed a basilar tuberculous meningitis and miliary tuberculosis in the peritracheal lymphatic glands, the liver, the spleen, and in ...

journal_title：Journal of neurosurgery

authors： González PR,Herrero CV,Joachim GF,Ocaña CR,Sevilla GC,Loyzaga PG

更新日期：1980-03-01 00:00:00

abstract：:Ischemic stroke remains a leading cause of morbidity and death for which few therapeutic options are available. The development of neuroprotective agents, a once promising field of investigation, has failed to translate from bench to bedside successfully. This work reviews the ischemic cascade, agents targeting steps ...

journal_title：Journal of neurosurgery

authors： Turner RC,Dodson SC,Rosen CL,Huber JD

更新日期：2013-05-01 00:00:00

abstract：:A feasibility study reveals that a standard linear accelerator, with only slight modification, can function in a manner similar to Leksell's multiple cobalt radiation device. A high radiation dose can be delivered to a 1-cm or 0.5-cm volume target with insignificant radiation effect on the surrounding tissue. ...

journal_title：Journal of neurosurgery

authors： Heifetz MD,Wexler M,Thompson R

更新日期：1984-04-01 00:00:00

abstract：OBJECT:Insight may be gained into the physiological mechanisms of deep brain stimulation (DBS) by analyzing local and contralateral subthalamic nucleus (STN) single-unit activity during activation of previously placed DBS electrodes. Special techniques are required to perform such analysis due to the presence of a larg...

journal_title：Journal of neurosurgery

authors： Toleikis JR,Metman LV,Pilitsis JG,Barborica A,Toleikis SC,Bakay RA

更新日期：2012-05-01 00:00:00

abstract：OBJECT:Inflammatory responses and oxygen free radicals have increasingly been implicated in the development of ischemic brain injury. In some cases, an attenuation of inflammation or free-radical injury can provide tissue protection. Diphosphoryl lipid A (DPL) is a detoxified derivative of a lipopolysaccharide (endotox...

journal_title：Journal of neurosurgery

authors： Toyoda T,Kassell NF,Lee KS

更新日期：2000-03-01 00:00:00

abstract：:OBJECT The present study was conducted to investigate whether microbleeds or microinfarcts are associated with apolipoprotein E (APOE) gene polymorphisms in patients with moyamoya disease (MMD), and if so, whetherAPOE gene polymorphisms are also associated with stroke type in patients with MMD. METHODS This cross-sect...

journal_title：Journal of neurosurgery

authors： Jang DK,Huh PW,Lee KS

更新日期：2016-06-01 00:00:00

abstract：:Fourteen cases of primary intracranial germ-cell tumors are presented. Histologically, there were eight germinomas, three teratomas, and three germ-cell tumors of more than one histological type. Immunohistochemical studies revealed alpha-fetoprotein in yolk-sac tumor components in two cases and beta human choriogonad...

journal_title：Journal of neurosurgery

authors： Shokry A,Janzer RC,Von Hochstetter AR,Yaşargil MG,Hedinger C

更新日期：1985-06-01 00:00:00

abstract：:To determine the risk of intracranial hemorrhage in patients with malignant gliomas who are treated with anticoagulant drugs for late postoperative venous thromboembolism, the authors retrospectively reviewed the computerized data base of all patients with primary brain tumors seen at the University of California, San...

journal_title：Journal of neurosurgery

authors： Choucair AK,Silver P,Levin VA

更新日期：1987-03-01 00:00:00

abstract：:Transcranial Doppler ultrasonography was used to monitor 71 patients suffering from intracranial hypertension with subsequent brain death. Among these, 29 patients were also assessed for systemic arterial pressure and epidural intracranial pressure, so that a correlation between cerebral perfusion pressure and the Dop...

journal_title：Journal of neurosurgery

authors： Hassler W,Steinmetz H,Gawlowski J

更新日期：1988-05-01 00:00:00

abstract：:Cerebral blood flow (CBF) was measured at different times during the first 150 minutes following an experimental space-occupying lesion produced with a 50-microliter microballoon in rats. Local CBF was measured with the carbon-14-labeled iodoantipyrine quantitative autoradiographic technique. A region of local ischemi...

journal_title：Journal of neurosurgery

authors： Kingman TA,Mendelow AD,Graham DI,Teasdale GM

更新日期：1987-11-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic and debilitating psychiatric condition. Traditionally, anterior capsulotomy (AC) was an established procedure for treatment of patients with refractory OCD. Over recent decades, deep brain stimulation (DBS) has gained popularity. In this paper the authors review the pub...

journal_title：Journal of neurosurgery

authors： Pepper J,Hariz M,Zrinzo L

更新日期：2015-05-01 00:00:00

abstract：:A patient with findings of bilateral cortical blindness and a unilateral carotid bruit is reported. A persistent trigeminal artery allowed emboli from a unilateral ulcerated internal carotid plaque to affect the visual cortex bilaterally. The angiographic findings and a brief discussion of this anomalous artery are pr...

journal_title：Journal of neurosurgery

authors： Heeney DJ,Koo AH

更新日期：1980-05-01 00:00:00

abstract：OBJECT:The hypogastric nerve (HGN) plays a crucial role in the primary functions of ejaculation: sperm transport through the vas deferens, secretion of prostatic fluid, and bladder neck closure. This study was undertaken to explore the possibility of restoring HGN function to the seminal tract and preserving its cross-...

journal_title：Journal of neurosurgery

authors： Kihara K,Sato K,Ishizaka K,Oshima H

更新日期：1998-04-01 00:00:00

abstract：:OBJECTIVETumors involving Meckel's cave remain extremely challenging because of the surrounding complex neurovascular structures and deep-seated location. The authors investigated a new minimal-access technique using the endoscopic transorbital approach (eTOA) through the superior eyelid crease to Meckel's cave and mi...

journal_title：Journal of neurosurgery

authors： Jeon C,Hong CK,Woo KI,Hong SD,Nam DH,Lee JI,Choi JW,Seol HJ,Kong DS

更新日期：2018-11-01 00:00:00

abstract：OBJECT:Complete avulsion traumatic brachial plexus injuries (BPIs) can be treated using nerve and musculoskeletal reconstruction procedures. However, these interventions are most viable within certain timeframes, and even then they cannot restore all lost function. Little is known about how patients make decisions rega...

journal_title：Journal of neurosurgery

authors： Franzblau LE,Maynard M,Chung KC,Yang LJ

更新日期：2015-06-01 00:00:00

abstract：OBJECT:In this prospective multicenter study the authors hypothesized that investigational epidural cortical stimulation (CS) delivered concurrently with rehabilitation therapy may enhance motor recovery following stroke. METHODS:Patients who had suffered their index stroke >or= 4 months previously were randomized int...

journal_title：Journal of neurosurgery

authors： Levy R,Ruland S,Weinand M,Lowry D,Dafer R,Bakay R

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:Direct brain compression and secondary injury due to increased intracranial pressure are believed to be the pathognomic causes of a grave outcome in acute subdural hemorrhage (aSDH). However, ischemic damage from aSDH has received limited attention. The authors hypothesized that cerebral microcirculation is a...

journal_title：Journal of neurosurgery

authors： Wang HC,Tsai JC,Lee JE,Huang SJ,Po-Hao Huang A,Lin WC,Hsieh ST,Wang KC

更新日期：2018-10-01 00:00:00

abstract：:OBJECTIVE The Agency of Healthcare Research and Quality (AHRQ) has defined Patient Safety Indicators (PSIs) for assessments in quality of inpatient care. The hypothesis of this study is that, in the treatment of unruptured cerebral aneurysms (UCAs), PSI events are less likely to occur in hospitals meeting the volume t...

journal_title：Journal of neurosurgery

authors： Washington CW,Taylor LI,Dambrino RJ,Clark PR,Zipfel GJ

更新日期：2018-08-01 00:00:00

abstract：:The authors report their investigation of the effects of high-dose barbiturates on the multimodality evoked response in 9 cats. After baseline evoked responses were obtained, boluses of pentobarbital were infused intravenously at regular intervals, amounting to cumulative total doses of 9, 18, 27, 45, 63, 123, and 183...

journal_title：Journal of neurosurgery

authors： Sutton LN,Frewen T,Marsh R,Jaggi J,Bruce DA

更新日期：1982-08-01 00:00:00