Primary intracranial germ-cell tumors. A clinicopathological study of 14 cases.

Abstract:

:Fourteen cases of primary intracranial germ-cell tumors are presented. Histologically, there were eight germinomas, three teratomas, and three germ-cell tumors of more than one histological type. Immunohistochemical studies revealed alpha-fetoprotein in yolk-sac tumor components in two cases and beta human choriogonadotropin in syncytiotrophoblastic giant cells in one case. One teratoma contained an unusual pleomorphic sarcomatous portion with features of early myoblastic differentiation. Comparison of intracranial with gonadal germ-cell tumors shows that the same subtypes are found in both locations with comparable incidence and similar biological behavior. The detailed World Health Organization classification of testicular germ-cell tumors should be applied to the histopathological classification of intracranial germ-cell tumors. Despite the critical location of intracranial germ-cell tumors, a good outcome can be achieved by optimal surgical excision. A primary microsurgical approach provides a histopathological diagnosis, which is indispensable for the proper choice of postoperative management.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Shokry A,Janzer RC,Von Hochstetter AR,Yaşargil MG,Hedinger C

doi

10.3171/jns.1985.62.6.0826

subject

Has Abstract

pub_date

1985-06-01 00:00:00

pages

826-30

issue

6

eissn

0022-3085

issn

1933-0693

journal_volume

62

pub_type

杂志文章
  • In vivo measurement of the frame-based application accuracy of the Neuromate neurosurgical robot.

    abstract:OBJECT:The application accuracy of the Neuromate neurosurgical robot has been validated in vitro but has not been evaluated in vivo for deep brain stimulation (DBS) electrode implantations. The authors conducted a study to evaluate this application accuracy in routine frame-based DBS procedures, with an independent sys...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.9.JNS14256

    authors: von Langsdorff D,Paquis P,Fontaine D

    更新日期:2015-01-01 00:00:00

  • Synergistic effect of basic fibroblast growth factor and methylprednisolone on neurological function after experimental spinal cord injury.

    abstract::The authors evaluated the effects of exogenous basic fibroblast growth factor (bFGF) in combination with intravenous methylprednisolone on neurological function and cord angiogenesis in a model of spinal cord injury. Cord injury was produced by extradural clip compression through a T-1 laminectomy. Rats were randomize...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.1.0105

    authors: Baffour R,Achanta K,Kaufman J,Berman J,Garb JL,Rhee S,Friedmann P

    更新日期:1995-07-01 00:00:00

  • Release of endothelium-derived relaxing factor after subarachnoid hemorrhage.

    abstract::The purpose of this study was to determine the cause of the loss of endothelium-dependent relaxation observed in chronic cerebral vasospasm. A bioassay system was developed to measure the release of endothelium-derived relaxing factor (EDRF) from canine basilar arteries. Subarachnoid hemorrhage (SAH) was induced in do...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.70.1.0108

    authors: Kim P,Lorenz RR,Sundt TM Jr,Vanhoutte PM

    更新日期:1989-01-01 00:00:00

  • Cerebral effects of hypocapnia plus nitroglycerin-induced hypotension in dogs.

    abstract::This study examined the effect of hypocapnia (PaCO2 20 mm Hg) on cerebral metabolism and the electroencephalogram (EEG) findings in 12 dogs during nitroglycerin (NTG)-induced hypotension. Previous studies suggest that NTG is a more potent cerebral vasodilator than sodium nitroprusside or trimethaphan. It was speculate...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1986.64.6.0924

    authors: Artru AA,Wright K,Colley PS

    更新日期:1986-06-01 00:00:00

  • Overall survival and response to radiation and targeted therapies among patients with renal cell carcinoma brain metastases.

    abstract:OBJECTIVE:The object of this retrospective study was to investigate the impact of targeted therapies on overall survival (OS), distant intracranial failure, local failure, and radiation necrosis among patients treated with radiation therapy for renal cell carcinoma (RCC) metastases to the brain. METHODS:All patients d...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.8.JNS182100

    authors: Juloori A,Miller JA,Parsai S,Kotecha R,Ahluwalia MS,Mohammadi AM,Murphy ES,Suh JH,Barnett GH,Yu JS,Vogelbaum MA,Rini B,Garcia J,Stevens GH,Angelov L,Chao ST

    更新日期:2019-01-18 00:00:00

  • Cerebellar astrocytoma: experience with 54 cases surgically treated at the Mayo Clinic, Rochester, Minnesota, from 1978 to 1990.

    abstract::A comprehensive review of the literature has shown that the treatment of choice for cerebellar astrocytomas has primarily been gross-total resection of the mass and gross-total resection of the enhancing portion of pilocytic astrocytomas. Most large scale studies of postresection survival rates of patients with cerebe...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.87.2.0257

    authors: Morreale VM,Ebersold MJ,Quast LM,Parisi JE

    更新日期:1997-08-01 00:00:00

  • Pituitary apoplexy associated with a triple bolus test. Case report.

    abstract::The authors report a case of pituitary apoplexy resulting in bilateral internal carotid artery occlusion, with marked depression of consciousness and hemiplegia. After transsphenoidal tumor decompression, restoration of flow in both carotid arteries was documented angiographically and the patient made an excellent cli...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.61.3.0586

    authors: Bernstein M,Hegele RA,Gentili F,Brothers M,Holgate R,Sturtridge WC,Deck J

    更新日期:1984-09-01 00:00:00

  • Cortical calculation localization using electrostimulation.

    abstract:OBJECT:A naming task has been used to spare cortical areas involved in language. In the present study, a calculation task was combined with electrostimulation mapping (awake surgery) to spare cortical areas involved in calculation in patients undergoing surgery for brain lesions. The organization of language and calcul...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2008.8.JNS17649

    authors: Roux FE,Boukhatem L,Draper L,Sacko O,Démonet JF

    更新日期:2009-06-01 00:00:00

  • Liposomes coupled with monoclonal antibodies against glioma-associated antigen for targeting chemotherapy of glioma.

    abstract::Liposomes have a variety of attributes as a drug delivery system. Targeting of liposomes to specific cells has been investigated by using appropriate cytophilic ligands such as monoclonal antibodies (MAb's). In the present study, liposomes with selective cytotoxicity toward glioma cells were obtained. An MAb which rea...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.71.3.0382

    authors: Kito A,Yoshida J,Kageyama N,Kojima N,Yagi K

    更新日期:1989-09-01 00:00:00

  • Peroneal neuropathy following successful bariatric surgery. Case report and review of the literature.

    abstract::Peroneal neuropathy has been observed in starvation, anorexia, and other situations of extreme weight loss. The authors report a case in which sequential bilateral peroneal neuropathies developed after successful bariatric surgery resulting in a weight loss of 114 lbs over 12 months. The diagnosis was confirmed using ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.105.4.631

    authors: Elias WJ,Pouratian N,Oskouian RJ,Schirmer B,Burns T

    更新日期:2006-10-01 00:00:00

  • Early surgical removal of migrated coil/stent after failed embolization of intracranial aneurysm.

    abstract:OBJECT:Distal coil or stent migration is a rare, but potentially morbid complication of intracranial aneurysm embolization. At present, there is no established standard of surgical evacuation of displaced material-in particular, there is no consensus on the optimum time for such intervention. The authors report their p...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2015.1.JNS132788

    authors: Turek G,Kochanowicz J,Lewszuk A,Lyson T,Zielinska-Turek J,Chwiesko J,Mariak Z

    更新日期:2015-10-01 00:00:00

  • Chronic subdural hematoma: surgical management in 133 patients.

    abstract::One hundred and thirty-three patients with chronic subdural hematoma were treated surgically between 1943 and 1980. The patients, aged 5 to 84 years, were graded retrospectively according to the Bender scale; 28% were in Grades 3 and 4. There were 107 unilateral and 26 bilateral hematomas. The clots were removed mostl...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.61.2.0263

    authors: Robinson RG

    更新日期:1984-08-01 00:00:00

  • MicroRNA and gene expression changes in unruptured human cerebral aneurysms.

    abstract::OBJECTIVE The molecular mechanisms behind cerebral aneurysm formation and rupture remain poorly understood. In the past decade, microRNAs (miRNAs) have been shown to be key regulators in a host of biological processes. They are noncoding RNA molecules, approximately 21 nucleotides long, that posttranscriptionally inhi...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2015.11.JNS151841

    authors: Bekelis K,Kerley-Hamilton JS,Teegarden A,Tomlinson CR,Kuintzle R,Simmons N,Singer RJ,Roberts DW,Kellis M,Hendrix DA

    更新日期:2016-12-01 00:00:00

  • Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction.

    abstract::OBJECTIVE: Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult bone marrow improves behavioral function in rat models of cerebral infarction. Although clinical studies are ongoing, most studies have focused on the acute or subacute phase of stroke. In the present study, MSCs derived from bone marr...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.5.JNS18140

    authors: Namioka T,Namioka A,Sasaki M,Kataoka-Sasaki Y,Oka S,Nakazaki M,Onodera R,Suzuki J,Sasaki Y,Nagahama H,Kocsis JD,Honmou O

    更新日期:2018-10-01 00:00:00

  • Primary myxoma of the parafalcine meninges. Case report.

    abstract::The authors report on an unusual case of a primary intracranial myxoma in a 39-year-old woman. The patient presented with headache and generalized seizure. Magnetic resonance imaging revealed a large right frontal tumor resembling a parasagittal meningioma. A gross-total resection was performed, and histological revie...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.104.3.440

    authors: Powers CJ,Pizzi CC,Cummings TJ,Friedman AH

    更新日期:2006-03-01 00:00:00

  • The course of chronic subdural hematomas after burr-hole craniostomy and closed-system drainage.

    abstract::A consecutive series of 32 adult patients with chronic subdural hematoma was studied in respect to postoperative cerebral reexpansion (reduction in diameter of the subdural space) after burr-hole craniostomy and closed-system drainage. Patients with high subdural pressure showed the most rapid brain expansion and clin...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1981.55.3.0390

    authors: Markwalder TM,Steinsiepe KF,Rohner M,Reichenbach W,Markwalder H

    更新日期:1981-09-01 00:00:00

  • Acute obstructive hydrocephalus associated with infratentorial subdural hygromas complicating Chiari malformation Type I decompression. Report of two cases and literature review.

    abstract::Obstructive hydrocephalus complicating foramen magnum decompression (FMD) for a Chiari malformation (CM) Type I is rare. Two female patients (17 and 55 years old) presented with strain-related headaches. In both cases magnetic resonance (MR) imaging studies confirmed a CM Type I, which was accompanied by syringomyelia...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2005.103.4.0752

    authors: Marshman LA,Benjamin JC,Chawda SJ,David KM

    更新日期:2005-10-01 00:00:00

  • Long-term follow-up of unruptured intracranial aneurysms repaired in California.

    abstract:OBJECT:Using a database that enabled longitudinal follow-up, the authors assessed the long-term outcomes of unruptured cerebral aneurysms repaired by clipping or coiling. METHODS:An observational analysis of the California Office of Statewide Health Planning and Development (OSHPD) database, which follows patients lon...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.3.JNS131159

    authors: Gonda DD,Khalessi AA,McCutcheon BA,Marcus LP,Noorbakhsh A,Chen CC,Chang DC,Carter BS

    更新日期:2014-06-01 00:00:00

  • Bone morphogenetic protein-2 application by a poly(D,L-lactide)-coated interbody cage: in vivo results of a new carrier for growth factors.

    abstract:OBJECT:Growth factors such as bone morphogenetic protein-2 (BMP-2) have been proven to promote spine fusion and to overcome the disadvantages of an autologous bone graft. The optimum method to deliver such growth factors remains a matter of discussion. The purpose of this study was to determine the safety and efficacy ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2002.97.1.0040

    authors: Kandziora F,Bail H,Schmidmaier G,Schollmeier G,Scholz M,Knispel C,Hiller T,Pflugmacher R,Mittlmeier T,Raschke M,Haas NP

    更新日期:2002-07-01 00:00:00

  • Comparison of clipping and coiling in elderly patients with unruptured cerebral aneurysms.

    abstract::OBJECTIVE The comparative effectiveness of the 2 treatment options-surgical clipping and endovascular coiling-for unruptured cerebral aneurysms remains an issue of debate and has not been studied in clinical trials. The authors investigated the association between treatment method for unruptured cerebral aneurysms and...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.1.JNS152028

    authors: Bekelis K,Gottlieb DJ,Su Y,O'Malley AJ,Labropoulos N,Goodney P,Lawton MT,MacKenzie TA

    更新日期:2017-03-01 00:00:00

  • Apoplectic lymphocytic hypophysitis. Case report.

    abstract::Pituitary apoplexy has not been reported in the setting of lymphocytic hypophysitis. The authors present the case of a woman with sudden vision loss and headache. Magnetic resonance imaging revealed focal hemorrhages in a sellar lesion with suprasellar extension. The results of histopathological analysis were consiste...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2003.98.1.0183

    authors: Lee MS,Pless M

    更新日期:2003-01-01 00:00:00

  • A dose-response study of dexamethasone in a model of spinal cord compression caused by epidural tumor.

    abstract::In order to assess the clinical and biological effects of glucocorticoids in the therapy of epidural spinal cord compression, the T8-10 epidural space of 50 rats was implanted with Walker 256 tumor. The rats were studied 10 to 20 days later when they became paraparetic. The regional blood-spinal cord transport constan...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.70.6.0920

    authors: Delattre JY,Arbit E,Thaler HT,Rosenblum MK,Posner JB

    更新日期:1989-06-01 00:00:00

  • Hook-rod with pedicle screw fixation for unstable spinal fracture. Technical note.

    abstract::A technique is described in which spinal fracture repositioning, decompression, and stabilization are achieved by a combination of hook-rod and pedicle screw fixation. This straightforward technique is useful for performing acute decompression in patients with partial neurological deficits and multisystem injuries. A ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Stancić MF,Mićović V,Potocnjak M

    更新日期:2000-01-01 00:00:00

  • Focal brain injury and upregulation of a developmentally regulated extracellular matrix protein.

    abstract::Tenascin is an extracellular matrix glycoprotein expressed during both normal development and neoplastic growth in both neural and nonneural tissues. During development of the central nervous system (CNS), tenascin is synthesized by glial cells, in particular by immature astrocytes, and is concentrated in transient bo...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.82.1.0106

    authors: Brodkey JA,Laywell ED,O'Brien TF,Faissner A,Stefansson K,Dörries HU,Schachner M,Steindler DA

    更新日期:1995-01-01 00:00:00

  • Correlation of thin fibrous cap possessing adipophilin-positive macrophages and intraplaque hemorrhage with high clinical risk for carotid endarterectomy.

    abstract:OBJECT:Preoperative clinical risk classification of carotid artery (CA) stenosis anticipates the outcome of CA intervention. A higher incidence of neurological morbidity was noted after CA stenting (CAS) in patients with medical risks than in those without risks. However, little is known about the correlation between c...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.8.JNS10423

    authors: Hao H,Iihara K,Ishibashi-Ueda H,Saito F,Hirota S

    更新日期:2011-04-01 00:00:00

  • Comparing the risks of frameless stereotactic biopsy in eloquent and noneloquent regions of the brain: a retrospective review of 284 cases.

    abstract:OBJECT:Frameless stereotactic biopsy has been shown in multiple studies to be a safe and effective tool for the diagnosis of brain lesions. However, no study has directly evaluated its safety in lesions located in eloquent regions in comparison with noneloquent locations. In this study, the authors determine whether an...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2009.3.JNS081695

    authors: Air EL,Leach JL,Warnick RE,McPherson CM

    更新日期:2009-10-01 00:00:00

  • Late (5-20 years) outcomes after STA-MCA anastomosis and encephalo-duro-myo-arterio-pericranial synangiosis in patients with moyamoya disease.

    abstract:OBJECTIVE:Surgical revascularization is known to reduce the incidence of further ischemic and hemorrhagic events in patients with moyamoya disease, but the majority of previous studies report only short-term (< 5 years) outcomes. Therefore, in this study the authors aimed to evaluate late (5-20 years) outcomes of moyam...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.12.JNS192938

    authors: Kuroda S,Nakayama N,Yamamoto S,Kashiwazaki D,Uchino H,Saito H,Hori E,Akioka N,Kuwayama N,Houkin K

    更新日期:2020-03-13 00:00:00

  • Invading meningiomas of the sphenoid ridge.

    abstract::The authors report a series of 34 meningiomas of the sphenoid ridge. Eight tumors were totally removed uneventfully: two from the middle sphenoid ridge and six from the pterion or Sylvian point. Five tumors were not operated on because of their extensions or the patient's age. Twenty-one tumors raised serious surgical...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1980.53.5.0587

    authors: Bonnal J,Thibaut A,Brotchi J,Born J

    更新日期:1980-11-01 00:00:00

  • Surgical treatment of multiple aneurysms and of incidentally-discovered unruptured aneurysms.

    abstract::Review of a series of 460 patients with spontaneous intracranial hemorrhage showed that 241 had demonstrable aneurysms and 38 had multiple aneurysms. The importance of demonstrating the entire circulation following ligation of one aneurysm is emphasized. Treatment of the 38 patients with multiple aneurysms is describe...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1971.35.3.0291

    authors: Moyes PD

    更新日期:1971-09-01 00:00:00

  • Complication of a large cranial defect. Case report.

    abstract::A patient with acute subdural hematoma was successfully treated with hemicraniectomy. He developed contralateral weakness 4 months after surgery which was reversed by cranioplasty. The presumptive mechanism is a gradient between atmospheric and intracranial pressure. Early cranioplasty is suggested to prevent this phe...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1976.44.4.0506

    authors: Tabaddor K,LaMorgese J

    更新日期:1976-04-01 00:00:00