A dose-response study of dexamethasone in a model of spinal cord compression caused by epidural tumor.

abstract：:The problem of implanted metals causing tissue damage by movement in patients exposed to MRI fields has produced a confusing welter of erroneous, pseudoscientific publications about magnetics, metals, medical equipment, and tissue compatibility. Quite simply, among the devices made for implantation, only those fabrica...

journal_title：Journal of neurosurgery

authors： McFadden JT

更新日期：2012-07-01 00:00:00

abstract：OBJECT:The prognosis of recurrent glioblastoma multiforme (GBM) remains unsatisfactory. The authors conducted a Phase II study of ifosfamide, carboplatin, and etoposide (ICE) for a first recurrence of GBM to determine whether it prolonged a patient's good-quality life. METHODS:This trial was an open-label, single-cent...

journal_title：Journal of neurosurgery

authors： Aoki T,Mizutani T,Nojima K,Takagi T,Okumura R,Yuba Y,Ueba T,Takahashi JA,Miyatake S,Nozaki K,Taki W,Matsutani M

更新日期：2010-01-01 00:00:00

abstract：OBJECT:Obsessive-compulsive disorder (OCD) is a common and disabling psychiatric illness, and in a significant proportion of patients with OCD the disease is refractory to conventional pharmacotherapy and psychotherapy. For more than half a century, patients with severe, treatment-resistant OCD have been treated with s...

journal_title：Journal of neurosurgery

authors： Sheth SA,Neal J,Tangherlini F,Mian MK,Gentil A,Cosgrove GR,Eskandar EN,Dougherty DD

更新日期：2013-03-01 00:00:00

abstract：:The ocular complications of intracarotid infusion of drugs for brain-tumor chemotherapy may be eliminated by infusion of the chemotherapeutic agent into the carotid artery above the origin of the ophthalmic artery. The authors have developed a catheter that can negotiate the carotid siphon. This catheter is not balloo...

journal_title：Journal of neurosurgery

authors： Kapp JP,Ross RL,Tucker EM

更新日期：1983-04-01 00:00:00

abstract：OBJECT:In the preceding article, the authors described the Hydrocephalus Outcome Questionnaire (HOQ), a simple, reliable, and valid measure of health status in children with hydrocephalus. In the present study, they present their initial experience in using the HOQ to quantify the health status in a typical cohort of c...

journal_title：Journal of neurosurgery

authors： Kulkarni AV,Drake JM,Rabin D,Dirks PB,Humphreys RP,Rutka JT

更新日期：2004-11-01 00:00:00

abstract：:The author describes the history of neurosurgery in Manitoba, with particular emphasis on events that occurred after his arrival there in 1950. Highlights of global neurosurgery are spliced into the author's reminiscences to anchor the local history with that of neurosurgery as a whole. ...

journal_title：Journal of neurosurgery

authors： Parkinson D

更新日期：1995-05-01 00:00:00

abstract：OBJECT:The Wilms tumor 1 (WT1) protein-a developmentally regulated transcription factor-is aberrantly expressed in gliomas and promotes their malignant phenotype. However, little is known about the molecular allies that help it mediate its oncogenic functions in glioma cells. METHODS:The authors used short interfering...

journal_title：Journal of neurosurgery

authors： Chidambaram A,Fillmore HL,Van Meter TE,Dumur CI,Broaddus WC

更新日期：2012-04-01 00:00:00

abstract：OBJECT:Stereotactic radiosurgery (SRS) is an important treatment option for patients with cavernous sinus meningiomas (CSM). To analyze factors associated with local tumor control and complications after single-fraction SRS, the authors reviewed cases involving patients treated with Gamma Knife SRS between 1990 and 200...

journal_title：Journal of neurosurgery

authors： Pollock BE,Stafford SL,Link MJ,Garces YI,Foote RL

更新日期：2013-09-01 00:00:00

abstract：:A case of solitary dorsal intramedullary schwannoma diagnosed by magnetic resonance imaging and treated surgically is reported. The authors review the previously published cases. The possible etiology of the tumor as well as some difficulties encountered in the diagnostic procedure and treatment are discussed. ...

journal_title：Journal of neurosurgery

authors： Herregodts P,Vloeberghs M,Schmedding E,Goossens A,Stadnik T,D'Haens J

更新日期：1991-05-01 00:00:00

abstract：:A computer-based system has been developed for the integration and display of computerized tomography (CT) image data in the operating microscope in the correct perspective without requiring a stereotaxic frame. Spatial registration of the CT image data is accomplished by determination of the position of the operating...

journal_title：Journal of neurosurgery

authors： Roberts DW,Strohbehn JW,Hatch JF,Murray W,Kettenberger H

更新日期：1986-10-01 00:00:00

abstract：:OBJECTIVE Mutations in the isocitrate dehydrogenase (IDH) genes are of proven diagnostic and prognostic significance for cerebral gliomas. The objective of this study was to evaluate the clinical feasibility of using a recently described method for determining IDH mutation status by using magnetic resonance spectrosco...

journal_title：Journal of neurosurgery

authors： Tietze A,Choi C,Mickey B,Maher EA,Parm Ulhøi B,Sangill R,Lassen-Ramshad Y,Lukacova S,Østergaard L,von Oettingen G

更新日期：2018-02-01 00:00:00

abstract：:The supplementary motor area (SMA) is a region located within each cerebral hemisphere at the posterior mesial border of the frontal lobe adjacent to the falx. The functional significance of this area has been somewhat unclear, and information regarding its influence on motor output has largely been based on evoked re...

journal_title：Journal of neurosurgery

authors： Rostomily RC,Berger MS,Ojemann GA,Lettich E

更新日期：1991-07-01 00:00:00

abstract：:The incidence of extracranial internal carotid artery (ICA) abnormalities, namely kinks, coils, and stenoses, was evaluated in a consecutive unselected series of 76 cases of single supratentorial saccular aneurysms submitted to bilateral carotid angiography. These patients were compared with a control group of 120 pat...

journal_title：Journal of neurosurgery

authors： Spallone A,Cantore G

更新日期：1981-11-01 00:00:00

abstract：:Sixteen patients referred for atlantoaxial fixation failures were treated surgically with revision procedures during the past decade. Of these 16 patients, atlantoaxial instability occurred because of rheumatoid arthritis in five, as odontoideum in seven, transverse ligament disruption in two, and odontoid fracture no...

journal_title：Journal of neurosurgery

authors： Dickman CA,Sonntag VK

更新日期：1995-08-01 00:00:00

abstract：OBJECT:Neck clipping or coil embolization cannot always achieve complete neck obstruction in wide-necked basilar artery (BA) bifurcation aneurysms. Clipping of the aneurysm body, leaving a small aneurysm rest, is one clipping method used for this kind of aneurysm to maintain the patency of the posterior cerebral arteri...

journal_title：Journal of neurosurgery

authors： Tanaka Y,Kobayashi S,Hongo K,Tada T,Nagashima H,Kakizawa Y

更新日期：2000-08-01 00:00:00

abstract：:The authors report the case of a newborn presenting at birth with macrocephaly and a large pineal region hemorrhagic cyst without neurological deficit. No neurosurgical intervention was performed, and subsequent imaging studies demonstrated complete involution of the cyst. ...

journal_title：Journal of neurosurgery

authors： Nimmagadda A,Sandberg DI,Ragheb J

更新日期：2006-04-01 00:00:00

abstract：OBJECT:Mitoxantrone is a drug with potent in vitro activity against malignant brain tumor cell lines; however, its effectiveness as a systemic agent has been hampered by poor central nervous system penetration and dose-limiting myelosuppression. To avoid these problems, we incorporated mitoxantrone into biodegradable p...

journal_title：Journal of neurosurgery

authors： DiMeco F,Li KW,Tyler BM,Wolf AS,Brem H,Olivi A

更新日期：2002-11-01 00:00:00

abstract：:Paget disease is an idiopathic metabolic disease of bone that may involve the axial and appendicular skeleton. In up to one third of patients there may be pagetoid involvement of the spine, which can cause back pain and vertebral collapse, with instability or myeloradiculopathy. Although medical therapy is the mainsta...

journal_title：Journal of neurosurgery

authors： Kremer MA,Fruin A,Larson TC 3rd,Roll J,Weil RJ

更新日期：2003-07-01 00:00:00

abstract：OBJECT:In this study the authors investigated the relationship between variations in the circle of Willis observed on magnetic resonance (MR) angiograms and locations of cerebral aneurysms, and evaluated the risk of aneurysm formation. METHODS:One hundred thirty-one patients with cerebral aneurysms were retrospectivel...

journal_title：Journal of neurosurgery

authors： Horikoshi T,Akiyama I,Yamagata Z,Sugita M,Nukui H

更新日期：2002-04-01 00:00:00

abstract：OBJECT:The object of this study was to examine the relationship between hospital volume and long-term mortality after treatment of intracranial aneurysms. METHODS:The authors identified patients treated for intracranial aneurysms between 2002 and 2010 from patient registries of Denmark, Norway, and Sweden, and linked ...

journal_title：Journal of neurosurgery

authors： Lindekleiv H,Mathiesen EB,Førde OH,Wilsgaard T,Ingebrigtsen T

更新日期：2015-09-01 00:00:00

abstract：:This case illustrates the potential growth rate of an atypical meningioma in a pediatric patient, emphasizes one of the potential risks after therapeutic radiation, and underscores the importance of clinical evaluation and follow up of the symptomatic patient after tumor resection and radiation therapy. The authors re...

journal_title：Journal of neurosurgery

authors： Ware ML,Cha S,Gupta N,Perry VL

更新日期：2004-05-01 00:00:00

abstract：:Pituitary apoplexy has not been reported in the setting of lymphocytic hypophysitis. The authors present the case of a woman with sudden vision loss and headache. Magnetic resonance imaging revealed focal hemorrhages in a sellar lesion with suprasellar extension. The results of histopathological analysis were consiste...

journal_title：Journal of neurosurgery

authors： Lee MS,Pless M

更新日期：2003-01-01 00:00:00

abstract：:A case is reported of a 45-year-old man who developed quadriplegia following a trivial motor-vehicle accident. Investigation including computerized tomography (CT) of the cervical spine revealed a large calcified lesion displacing the spinal cord and nerve roots, which proved to be a tuberculoma. The case is unusual i...

journal_title：Journal of neurosurgery

authors： Compton JS,Dorsch NW

更新日期：1984-01-01 00:00:00

abstract：:Adults and children with low-grade gliomas often present with medically refractory epilepsy. Currently, controversy exists regarding the need for intraoperative electrocorticography (ECoG) to identify and, separately, resect seizure foci versus tumor removal alone to yield maximum seizure control in this patient popul...

journal_title：Journal of neurosurgery

authors： Berger MS,Ghatan S,Haglund MM,Dobbins J,Ojemann GA

更新日期：1993-07-01 00:00:00

abstract：:Because it has been difficult to predict the outcome of patients with head injury in the early period after admission, a clinical study was undertaken to evaluate if the fibrinolytic parameters could be reliable indicators of outcome. Seventy patients presenting with head injury without obvious trauma in other regions...

journal_title：Journal of neurosurgery

authors： Takahashi H,Urano T,Takada Y,Nagai N,Takada A

更新日期：1997-05-01 00:00:00

abstract：:The authors report a case in which sellar and suprasellar osteogenic sarcoma developed 10 years after radiation therapy for pituitary adenoma. The literature is reviewed and the rarity of this condition discussed. ...

journal_title：Journal of neurosurgery

authors： Amine AR,Sugar O

更新日期：1976-01-01 00:00:00

abstract：OBJECT:Selective dorsal rhizotomy (SDR) has been shown to provide considerable benefit to children with spastic cerebral palsy (CP). The authors sought to evaluate the risks of postoperative spinal deformities in patients following SDR. METHODS:All patients who underwent SDR at McGill University between 1991 and 2001 ...

journal_title：Journal of neurosurgery

authors： Golan JD,Hall JA,O'Gorman G,Poulin C,Benaroch TE,Cantin MA,Farmer JP

更新日期：2007-06-01 00:00:00

abstract：OBJECT:Ventricular infection after ventriculostomy placement carries a high mortality rate. Responding to ventriculostomy infection rates, a multidisciplinary performance improvement team was formed, a comprehensive protocol for ventriculostomy placement was developed, and the efficacy was evaluated. METHODS:A best-pr...

journal_title：Journal of neurosurgery

authors： Kubilay Z,Amini S,Fauerbach LL,Archibald L,Friedman WA,Layon AJ

更新日期：2013-03-01 00:00:00

abstract：:The central canal of the human spinal cord is partially or completely occluded in the vast majority of individuals by the early years of adult life. The authors describe an experimental lesion following virus-induced ependymitis that bears a striking resemblance to the condition in man. Suckling hamsters were inoculat...

journal_title：Journal of neurosurgery

authors： Milhorat TH,Kotzen RM

更新日期：1994-07-01 00:00:00

abstract：OBJECT:The application accuracy of the Neuromate neurosurgical robot has been validated in vitro but has not been evaluated in vivo for deep brain stimulation (DBS) electrode implantations. The authors conducted a study to evaluate this application accuracy in routine frame-based DBS procedures, with an independent sys...

journal_title：Journal of neurosurgery

authors： von Langsdorff D,Paquis P,Fontaine D

更新日期：2015-01-01 00:00:00