[Comparative efficacy, safety, cardio-hemodynamic effects of isosorbide dinitrate (ID) aerosol and sublingual tablets of nitroglycerin].

Abstract:

AIM:To study efficacy, safety, cardiohemodynamic effects of ID aerosol--isoket--for relief of anginal attacks and their prevention in long-term treatment. MATERIALS AND METHODS:15 patients with ischemic heart disease suffering from stable angina class II-III. Isoket was tried for efficacy, tolerance, hemodynamic parameters, morphofunctional status of the heart, exercise tolerance. RESULTS:Isoket aerosol in a dose 1.25 mg as a single oral spray arrested anginal attacks in all the patients. In long-term regimens good antianginal effect was achieved in 60% of cases. The ID aerosol produces a fast antianginal effect, improves morphofunctional cardiac parameters and exercise tolerance. CONCLUSION:Isoket spray is effective and safe antianginal drug.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Ol'binskaia LI,Sizova ZhM,Ushakova AV

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

69-72

issue

5

eissn

0040-3660

issn

2309-5342

journal_volume

70

pub_type

杂志文章
  • [Dynamics of respiratory function and and bicycle ergometry in the treatment of patients with chronic circulatory failure].

    abstract::Data are presented on external respiration at rest and during exercise (bicycle ergometry) in 20 patients with chronic circulatory insufficiency due to a variety of heart diseases, as well as variation in the above in the course of treatment with digoxin and calcium antagonist corinfar. External respiration parameters...

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    pub_type: 杂志文章

    doi:

    authors: Ordian MM,At'kov OIu,Kassirskiĭ SG,Sobol' IuS

    更新日期:1986-01-01 00:00:00

  • [The etiopathogenetic bases for antibacterial therapy and prevention of urinary tract infections].

    abstract::The paper discusses the pathogenesis of urinary tract infections, the mechanisms of resistance in their pathogens to antimicrobials and uroseptics, and approaches to defining patient management tactics. :В статье обсуждается патогенез инфекций мочевых путей, механизмы формирования устойчивости их возбудителей к антиб...

    journal_title:Terapevticheskii arkhiv

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    doi:10.17116/terarkh20158711123-133

    authors: Kayukov IG

    更新日期:2015-01-01 00:00:00

  • [State of the upper respiratory tract in patients with stage I arterial hypertension].

    abstract:AIM:To study morphofunctional features of the upper airways (UAW) in wakeful patients (juveniles with arterial hypertension stage I) and genetic predisposition to UAW obstruction in sleeping patients. MATERIAL AND METHODS:The examination of 18 juveniles with arterial hypertension stage I and II normotensive juveniles ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Voronin IM,Stegachev SK,Pokidkin AV,Temartseva TP,Belov AM,Chuchalin AG

    更新日期:2001-01-01 00:00:00

  • [Evaluation of the efficiency of diagnostic regimens for enterohemorrhagic escherichiasis. Etiological verification of hemolytic uremic syndrome in the Russian Federation].

    abstract:AIM:To evaluate the practical efficiency of the diagnostic algorithms for enterohemorrhagic escherichiasis, which are laid down by the current normative documents of the Russian Federation. SUBJECTS AND METHODS:The investigators estimated the prevalence of enterohemorrhagic Escherichia coli (EHEC) infection in childre...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Podkolzin AT,Konovalova TA,Veselova OA

    更新日期:2014-01-01 00:00:00

  • [Depression in cardiological practice: pilot results from a multicenter clinico-epidemiological trial in hypertensive patients with ischemic heart disease (koordinata)].

    abstract:AIM:To study effects of depression on the course and prognosis of arterial hypertension (AH) and coronary heart disease (CHD), potentialities of the combined treatment in a prospective multicenter trial. MATERIAL AND METHODS:A total of 376 patients with AH and/or CHD having depression (10 scores and higher by HADS sca...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:

    authors: Chazov EI,Oganov RG,Pogosova GV,Shal'nova SA,Romasenko LV,Shchurov DV

    更新日期:2006-01-01 00:00:00

  • Differences between passport and biological (actual) age in the population of Russian patients suffering from arterial hypertension (analysis of the «Hyperion» register).

    abstract:AIM:The aim of the study was to analyze the severity of the difference in these values in real clinical practice in patients suffering from arterial hypertension (AH) on the basis of an open multicenter register to monitor the effectiveness of therapy in patients with hypertension "HYPERION", conducted by the Eurasian ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890421-28

    authors: Arutyunov AG,Nozdrin AV,Shavgulidze KB,Tokmin DS,Osadchiy IV

    更新日期:2018-04-19 00:00:00

  • [The efficacy of combinations of anti-arrhythmia preparations in patients with the paroxysmal form of atrial fibrillation].

    abstract::The efficacy of allapinin, ethacizine, ritmilen, kinilentin, obsidan and finoptin given alone and in different combinations was studied in 44 patients with paroxysmal atrial fibrillation provoked by transesophageal pacing. The use of the combinations of the drugs belonging to the first group as well of those of the fi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Abdalla A,Mazur NA,Iavorskaia NV,Sitina VK

    更新日期:1992-01-01 00:00:00

  • [Serum level of secretory phospholipase A2 (sPLA2) as a predictor of restenosis after coronary angioplasty].

    abstract:AIM:To elucidate whether secretory phospholipase A2 (sPLA2) level in the blood and catalytic activity are significant predictors of restenosis after coronary angioplasty (CAP). MATERIAL AND METHODS:Samples of venous blood were obtained from 24 patients before CAP and 1, 3, 6 days and 6 months after it. sPLA2 was measu...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Korotaeva AA,Provatorov SI,Samoĭlova EV,Kaminnyĭ AI,Sumarokov AB,Pirkova AA,Samko AN,Prokazova NV

    更新日期:2002-01-01 00:00:00

  • [Involvement of the hepatobiliary system and pancreas in obesity].

    abstract::The article provides an overview of current views on the involvement of the liver, gallbladder, and pancreas in patients with overweight and obesity. It considers the general issues of the pathogenesis of these conditions, their clinical features and diagnostic methods. :В статье приводится обзор современных взглядов...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.17116/terarkh2017891128-133

    authors: Akhmedov VA,Gaus OV

    更新日期:2017-01-01 00:00:00

  • [Possibility of complete recovery in multiple myeloma].

    abstract::In three patients with multiple myeloma, stage IIIA, a complete remission lasting from 6 to 8 years was attained, in spite of the fact that not all of them received treatment. In the latter case the remission lasted from 5 to 6 years. One of the patients had diffuse Gk + BIk myeloma, one presented with multiple focal ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Andreeva NE

    更新日期:1985-01-01 00:00:00

  • [Antibodies to cyclic citrullinized peptide in rheumatoid arthritis].

    abstract:AIM:To estimate a diagnostic value of antibodies to cyclic citrullinized peptide (CCP) in rheumatoid arthritis (RA). MATERIAL AND METHODS:The study was made of 85 RA patients. Of them, 48 patients had early RA, i.e. of 8 month and less duration. The control group consisted of 35 patients with non-differentiated arthri...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Aleksandrova EN,Chemeris NA,Karateev DE,Novikov AA,Brodetskaia KA,Nasonov EL

    更新日期:2004-01-01 00:00:00

  • [Highly sensitive methods for the serological,diagnosis of hepatitis B and their clinico-epidemiological significance].

    abstract::A study was made of HB-virus infection markers in 438 patients of different age with hepatitis B. Highly sensitive methods based on the test systems manufactured in this country and abroad were employed. The authors established the diagnostic importance of HBV markers, studied the prevalence of those markers in parent...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Botsvadze ESh,Aleksishvili MM,Gegeshidze TN,Mosakhlishvili NG

    更新日期:1990-01-01 00:00:00

  • [Treatment of patients with HBV cirrhosis: successes, unsolved problems].

    abstract::Annually 0.5-1 million people die from terminal liver injuries or hepatocellular carcinoma, which are associated with hepatitis B virus (HBV); 5-10% of liver transplantations are performed due to the outcomes of HBV infections. All patients with liver cirrhosis in the outcome of replication-phase chronic hepatitis B n...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Bakulin IG,Khaĭmenova TIu,Sidorova IO

    更新日期:2013-01-01 00:00:00

  • [Hemostatic disorders and their implication in the pathogenesis of Astrakhan rickettsial fever].

    abstract:AIM:to define a role of hemostatic disorders in the pathogenesis of Astrakhan rickettsial fever (ARL). SUBJECTS AND METHODS:Platelet functional activity and plasma hemostatic parameters were studied in 89 patients of moderate ARL. RESULTS:The clinical manifestations of hemostatic disorders at the height of ARL were c...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Maleev VV,Galimzianov KhM,Lazareva EN,Poliakova AM,Astrina OS,Kudriavtsev VA,Arshba TE

    更新日期:2009-01-01 00:00:00

  • [The nature of changes in central hemodynamics and myocardial contractile capacity of the left ventricle during volumetric loading in patients with chronic alcoholism in relation to the duration of alcohol abuse].

    abstract::Forty patients aged 33 to 66 years suffering from chronic alcoholism, stages II-III, were examined. All the patients were subjected to contrast ventriculography before and after exercise test to identify the latent forms of heart failure. According to the coronarography findings, 9 out of the 40 patients demonstrated ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Smetnev AS,Batyraliev TA,Belogubets VI,Grudtsyn GV,Drozdov ES

    更新日期:1989-01-01 00:00:00

  • [Characteristics of the dynamic outpatient observation of workers at an industrial enterprise].

    abstract::A computer-assisted staged system of a follow-up of factory workers with CHD and diabetes mellitus was developed. It included automated screening by questionnaire, ECG and biochemical screening, physical examination, investigation of the basic carbohydrate-lipid indices, more detailed examination in out- or inpatients...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kamysheva EP,Suvorov AV,Strongin LG

    更新日期:1988-01-01 00:00:00

  • [Characteristics of blood pressure in schoolchildren 7-17 years old (based on one-stage and prospective studies)].

    abstract::One-stage epidemiological survey permitted one to define the limits of normal blood pressure values in schoolchildren aged 7-17 years for each age-sexual group differentially. Isolated blood pressure elevation was found to be rare, amounting to 4.4% in boys and to 3.1% in girls. The rate of new cases of elevated blood...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tubol IB,Il'chenko IN,Akhmeteli MA,Zhukovskiĭ GS,Burlutskiĭ GI

    更新日期:1984-01-01 00:00:00

  • [The initial results of the sanatorium rehabilitation of patients having had an acute myocardial infarct in a mid-alpine climate].

    abstract::Short-term results of rehabilitation of 1046 CHD patients at a cardiological sanatorium in mountains at average altitude (1600 m above the sea level) were studied. Large focal myocardial infarction (MI) was found in 738 of them, small focal MI in 249, and acute focal myocardial dystrophy of ischemic genesis in 59. Of ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Murataliev TM,Satkynalieva ZT,Kozhanov AS,Tsoĭ SM,Toktosunova AN

    更新日期:1988-01-01 00:00:00

  • [The clinical manifestations and differential diagnosis of Yersinia hepatitis and viral hepatitis A and B].

    abstract::Hepatic involvement in yersiniosis is associated with clinical symptoms of hepatitis, sometimes dominant in the clinical picture. Such cases need differentiation of yersiniosis with viral hepatitides A and B. Clinical and biochemical findings were compared for matched patients with yersiniosis-induced hepatic lesions,...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shakhgil'dian DI,Iushchuk ND,Karetkina GN,Braginskiĭ DM,Doroshenko NV,Sergeeva NA

    更新日期:1993-01-01 00:00:00

  • [Systolic and diastolic intraventricular asynchrony of the left ventricular myocardium in patients with pacemaker].

    abstract:AIM:To study intraventricular asynchrony and effects of pacemaker implantation on asynchrony severity in patients with rhythm and conduction disorders. MATERIAL AND METHODS:The study of 46 patients with cardiac arrhythmia (atrial fibrillation, sick sinus syndrome, AB-block of the third degree) included such examinatio...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: At'kov OIu,Popova EIu,Gorokhova SG

    更新日期:2012-01-01 00:00:00

  • [Clinical implication of urine test for markers of endothelial dysfunction and angiogenesis factors in assessment of tubulointerstitial fibrosis in chronic glomerulonephritis].

    abstract:AIM:To evaluate contribution of endothelial dysfunction and impairment of endothelial proliferation/ regeneration to mechanisms of development of tubulointerstitial fibrosis (TIF) in chronic glomerulonephritis (CGN) basing on urinary levels of markers of endothelial activation/impairment and angiogenesis factors. MATE...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Bobkova IN,Kozlovskaia LV,Rameeva AS,Varshavskiĭ VA,Golitsyna EP

    更新日期:2007-01-01 00:00:00

  • [Hypertension and "silent" myocardial ischemia. I. The results of stress scintigraphy of the myocardium in patients].

    abstract::As many as 24 patients suffering from essential hypertension (EH) were examined. The patients were subjected to Holter ECG monitoring, echocardiography, coronary angiography, exercise scintigraphy of the myocardium with transesophageal pacing of the atria and the dipyridamole test. The patients manifested defects of t...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Dubov PB,Koniaeva EB,Ostroumov VB,Sergienko VB,Iurenev AP

    更新日期:1992-01-01 00:00:00

  • Application of bacterial therapeutic vaccine Immunovac-VP4 in the treatment of pollinosis.

    abstract:AIM:The aim of the study was to study the effectiveness of the complex use of bacterial therapeutic vaccine Immunovac-VP4 and allergen-specific immune therapy (ASIT) in pollinosis in children and adults. MATERIALS AND METHODS:Bacterial therapeutic vaccine Immunovac-VP4 was used annually, nasal and oral administration ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890316-20

    authors: Kostinov MP,Poddubikova AM,Magarshak OO,Poddubikov AV

    更新日期:2018-04-19 00:00:00

  • [Study of the characteristics of various hematologic diseases using monoclonal antibodies LT1, LT2 and LT7].

    abstract::Monoclonal antibodies (MCA) LT1, LT2 and LT7 were characterized. It was established that MCA LT1 and LT2 (IgG1 and IgM classes, respectively) interacted with antigen 67 kD, and MCA LT7 (IgGZa)--with antigen 40 kD. MCA LT1, LT2 and LT7 were shown to identify normal and neoplastic cells of T-lymphoid type. MCA LT1 and L...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Filatov AV,Tsveĭbakh AS,Kazhdan IIa,Bachurin PS,Klubovskaia NI

    更新日期:1989-01-01 00:00:00

  • [The potentials of intestinoscopy and guided biopsy in the diagnosis of diseases of the small intestine].

    abstract:AIM:To ascertain the role of intestinoscopy in diagnosis of small intestinal diseases. MATERIALS AND METHODS:Intestinoscopy with multiple topographic biopsies was made with SIF-10 device (Olympus) in 92 patients. RESULTS:Of 60 patients with absorption disorders, the diagnosis of gluten enteropathy (GEP), Whipple's di...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Loginov AS,Parfenov AI,Vasil'ev IuV,Chikunova BZ,Parfenov DA

    更新日期:1999-01-01 00:00:00

  • [Hemodynamics and anaerobic glycolysis during the head-down tilt test in myocarditis patients].

    abstract::The analysis is presented of the changes observed in hemodynamics and anaerobic metabolism in myocarditis patients given increasing preload. It is shown that the antiorthostatic test can specify substantial deposition of blood in the lesser or greater circulation. Patients with congestive cardiac insufficiency demonst...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Mravian SR,Paleev NR,Sharapov GN,Iankovskaia MO,Demidov IN

    更新日期:1994-01-01 00:00:00

  • [Influenza and acute respiratory viral infections. A role of a polyclinic therapist in timely diagnosis and treatment].

    abstract::The paper emphasizes a role of a local therapist in the timely detection and treatment of acute respiratory viral infections. It shows a certain difficulty in the differential diagnosis of acute respiratory disease and influenza. Attention is given on a need for a well-defined program to correct drug therapy, regimen,...

    journal_title:Terapevticheskii arkhiv

    pub_type: 社论

    doi:

    authors: Galkin VA

    更新日期:2010-01-01 00:00:00

  • [The role of the renin-angiotensin system in the pathogenesis of nephrotic syndrome].

    abstract::The state of the renin-angiotensin system (RAS) was studied in 102 patients with chronic glomerulonephritis with the nephrotic syndrome (NS) with relation to a phase of the edematous syndrome and sodium balance. Heterogeneity of patients with NS was shown with regard to RAS activity and the circulating blood volume in...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kutyrina IM,Klepikov PV,Tareeva IE

    更新日期:1988-01-01 00:00:00

  • [Effectiveness of the treatment of severe aplastic anemia (splenectomy and immunosuppression)].

    abstract::The authors appraise the efficacy of the treatment of severe aplastic anemia by splenectomy, antilymphocyte globulin and cyclophosphamide. A total of 120 patients were placed under observation. Of these, 103 patients had a severe disease pattern, one hundred and 112 patients with aplastic anemia including 96 with a se...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Idel'son LI,Pogorel'skaia EP,Il'in GP,Gorodetskiĭ VM

    更新日期:1984-01-01 00:00:00

  • [Avelox efficacy in the treatment of acute purulent rhinosinusitis].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ivanchenko OA,Chuchueva NG,Lopatin AS

    更新日期:2007-01-01 00:00:00