Comparative analysis of adiponectin isoform distribution in pregnant women with gestational diabetes mellitus and after delivery.

Abstract:

OBJECTIVE:To evaluate the distribution of circulating adiponectin isoforms in pregnant women with gestational diabetes mellitus (GDM) and compare isoform distribution changes 12 months after delivery. DESIGN CROSS-SECTIONAL STUDY SETTING:University Hospital. POPULATION:Sixty-four consecutive pregnant women who underwent routine prenatal tests for GDM between 24 and 28 weeks of gestation. The study group included 36 women diagnosed with GDM, 30 of whom underwent re-testing for diabetes 12 months after delivery. The control group included 28 healthy pregnant women. METHODS:Quantitative determination of total adiponectin and its isoforms in serum was performed with the multimeric adiponectin enzyme-linked immunosorbent assay. RESULTS:Total adiponectin concentration in women with GDM was significantly lower than in women without GDM. Among adiponectin isoforms, significantly lower concentrations of multimers and trimers in women with GDM were found in comparison to controls, while the concentration of hexamers did not differ between the groups. After delivery, a significant increase in total adiponectin and in the concentration of multimers and trimers was found in women with history of GDM. Additionally, we found that multimers and hexamers were negatively correlated with body mass index before and during gestation, as well as after delivery, and middle molecular weight isoforms in gestation were negatively correlated with birthweight. CONCLUSIONS:Hypoadiponectinemia during GDM was characterized by a significant, reversible decrease in multimeric levels; thus this isoform seems to function in a cohesive way with total adiponectin. Negative correlations of adiponectin isomers with body mass index indicate that there is a possibility to normalize total adiponectin and prevent GDM.

authors

Matuszek B,Burska A,Leszczyńska-Gorzelak B,Donica H,Nowakowski A

doi

10.1111/aogs.12137

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

951-9

issue

8

eissn

0001-6349

issn

1600-0412

journal_volume

92

pub_type

杂志文章
  • Oral misoprostol vs. vaginal gemeprost prior to surgical termination of pregnancy in nulliparae.

    abstract:BACKGROUND:To compare the efficacy and side-effects of intravaginal gemeprost with those of oral misoprostol for cervical ripening prior to first-trimester pregnancy termination in nulliparous women. METHODS:Retrospective analysis of surgical terminations of pregnancy performed before 90 days of gestation. Intravagina...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2004.00441.x

    authors: Celentano C,Prefumo F,Di Andrea O,Presti F,Di Nisio Q,Rotmensch S

    更新日期:2004-08-01 00:00:00

  • Maternal risk factors for postterm pregnancy and cesarean delivery following labor induction.

    abstract:OBJECTIVE:To investigate risk factors associated with postterm pregnancy and cesarean delivery following labor induction. DESIGN:Population-based cohort study. SETTING:Sweden. POPULATION:From the Swedish Medical Birth Register, a total of 1,176,131 singletons births from gestational week 37 and onwards, between 1992...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349.2010.500009

    authors: Roos N,Sahlin L,Ekman-Ordeberg G,Kieler H,Stephansson O

    更新日期:2010-08-01 00:00:00

  • Obstetric outcome in patients with unexplained infertility: comparison of treatment-related and spontaneous pregnancies.

    abstract:BACKGROUND:The aim of this study was to determine the long-term prognosis of fecundity among couples with unexplained infertility and to compare pregnancy course and outcome in spontaneous versus treatment-related pregnancies. METHODS:A prospective follow-up study of 70 couples with a diagnosis of unexplained infertil...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Isaksson R,Tiitinen A

    更新日期:1998-09-01 00:00:00

  • Uterine artery Doppler measurements during first and second trimesters of normal pregnancy.

    abstract:INTRODUCTION:The aim of this study was to construct a reference curve based on longitudinal Doppler blood flow measurements of the uterine artery during the first and second trimesters of normal pregnancy. MATERIAL AND METHODS:Healthy pregnant women (n = 124) between 18 and 38 years of age were included. The uterine a...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13073

    authors: Stridsklev S,Salvesen Ø,Salvesen KÅ,Carlsen SM,Husøy MA,Vanky E

    更新日期:2017-03-01 00:00:00

  • Meconium stained amniotic fluid is associated with maternal infectious morbidity in pre term delivery.

    abstract::The purpose of the study was to determine if intra partum meconium stained amniotic fluid (MSAF) is associated with infectious morbidity in women with pre term delivery. The study group was composed of 89 women with pre term delivery and MSAF. The control group comprised 89 women with pre term delivery and clear amnio...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349309058159

    authors: Markovitch O,Mazor M,Shoham-Vardi I,Chaim W,Leiberman JR,Glezerman M

    更新日期:1993-10-01 00:00:00

  • Aortic valve replacement during pregnancy. A case report and review of the literature.

    abstract::Aortic stenosis (AS) is an uncommon complication during pregnancy, but when it occurs it results in significant maternal and fetal morbidity and mortality. We present a gravida with severe AS in which aortic valve replacement was performed in the 3rd trimester of her pregnancy. She had severe AS with mild aortic regur...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349009028713

    authors: Ben-Ami M,Battino S,Rosenfeld T,Marin G,Shalev E

    更新日期:1990-01-01 00:00:00

  • Clinical care of diabetic pregnancies in Northern Finland 1967-1987.

    abstract::Diabetic pregnancies are risk pregnancies with increased perinatal mortality and perinatal morbidity. The purpose of this study was to evaluate retrospcctively the outcome of 567 diabetic pregnancies in the area of Oulu University Hospital periodically from 1967 to 1987. ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409029416

    authors: Anttila M

    更新日期:1994-10-01 00:00:00

  • Factors associated with cone margin involvement in CIN patients undergoing conization-equivalent electrosurgical procedure.

    abstract:BACKGROUND:Most studies of cervical conization have considered the frequency of complications and the outcome of follow-up. The determinants of cone margin positivity have been inadequately described. In a series of CIN patients undergoing conization-equivalent electrosurgical procedure, we evaluated the factors associ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Costa S,De Nuzzo M,Terzano P,Santini D,De Simone P,Bovicelli A,Bovicelli L,Bucchi L

    更新日期:2000-07-01 00:00:00

  • Prognostic factors and long-term results of the Burch colposuspension. A retrospective study.

    abstract::The purpose of this retrospective study was to evaluate the importance of different preoperative estimates and postoperative complications on the outcome of the Burch colposuspension with respect to urinary continence. During the period 1980-1988 243 women were operated upon with the Burch colposuspension for stress i...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409013459

    authors: Kjølhede P,Rydén G

    更新日期:1994-09-01 00:00:00

  • Relapsing thymic carcinoma during pregnancy.

    abstract::A 23 year old woman, who was known to be in remission from thymic carcinoma, presented in her first trimester. She had previously been treated with radiation and chemotherapy. Her pregnancy was complicated by fever and contractions at 30 weeks and ended with the birth of a live preterm male infant. Subsequent investig...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349209021082

    authors: Peleg D,Zabari A,Shalev E

    更新日期:1992-07-01 00:00:00

  • Chromosomal anomalies in first-trimester miscarriages.

    abstract:BACKGROUND:It is well known that a large proportion of first-trimester spontaneous abortions is caused by chromosomal disorders. The present study represents a unique material and the success rate of the karyotyping was high. METHODS:Chromosomal analysis from chorionic villus sampling of 259 of 304 consecutive first-t...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2005.00882.x

    authors: Ljunger E,Cnattingius S,Lundin C,Annerén G

    更新日期:2005-11-01 00:00:00

  • Health-related quality of life in women with endometriosis, compared with the general population and women with rheumatoid arthritis.

    abstract:INTRODUCTION:Women with endometriosis have reduced health-related quality of life (HRQoL). However, comparisons to the general population and other patient groups are lacking. MATERIAL AND METHODS:The present cross-sectional questionnaire study included 157 women with endometriosis, 156 women from the general populati...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13427

    authors: Verket NJ,Uhlig T,Sandvik L,Andersen MH,Tanbo TG,Qvigstad E

    更新日期:2018-11-01 00:00:00

  • Pharmacokinetics of 250 μg anti-D IgG in the third trimester of pregnancy: an observational study.

    abstract:OBJECTIVE:We present a pharmacokinetic study evaluating a single intramuscular dose of 250 μg anti-D immunoglobulin in the third trimester of pregnancy. The aim of the study was to determine the kinetic profile and duration of detectable levels of anti-D. DESIGN:Prospective observational study. SETTING:Antenatal outp...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2012.01377.x

    authors: Tiblad E,Wikman A,Rane A,Jansson Y,Westgren M

    更新日期:2012-05-01 00:00:00

  • Gonadal steroids, gonadotropins and endometrial histology in postmenopausal women with malignant ovarian tumors.

    abstract::The concentrations of FSH, LH, 17-beta-estradiol (E2), estrone (E1) and progesterone (P) were measured in peripheral and ovarian vein sera obtained at preoperative pelvic angiography from 5 postmenopausal women with malignant ovarian tumors. In 5 others the concentrations of E2, P and testosterone (T) were also measur...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348609155172

    authors: Jeppsson S,Karlsson S,Kullander S

    更新日期:1986-01-01 00:00:00

  • Very short cervix in low-risk asymptomatic singleton pregnancies: Outcome according to treatment and cervical length at diagnosis.

    abstract:INTRODUCTION:The aim of this study was to explore the outcome of low-risk singleton pregnancies with very short cervical length (CL ≤15 mm) according to method of treatment and CL at diagnosis. MATERIAL AND METHODS:Retrospective study on singleton pregnancies devoid of risk factors for spontaneous preterm delivery ide...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13881

    authors: Souka AP,Papamihail M,Pilalis A

    更新日期:2020-11-01 00:00:00

  • Fetal ponderal index as an instrument for further classification of intra-uterine growth retardation.

    abstract::Perinatal morbidity and mortality are still high in cases of intra-uterine growth retardation. Present screening methods select large risk groups and have a low positive predictive value. Instruments which could be used as indicators for those cases within the risk group needing close fetal monitoring would be valuabl...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349209009916

    authors: Vilbergsson G,Wennergren M

    更新日期:1992-04-01 00:00:00

  • Perceptions of oocyte banking from women intending to circumvent age-related fertility decline.

    abstract:INTRODUCTION:Women can now opt to bank their oocytes with the intention of increasing their chances of achieving a pregnancy after their fertility has declined. This exploratory study aimed to gain insight into how women, considering oocyte banking to circumvent age-related fertility decline, perceive this intervention...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13019

    authors: de Groot M,Dancet E,Repping S,Goddijn M,Stoop D,van der Veen F,Gerrits T

    更新日期:2016-12-01 00:00:00

  • Peritoneal tuberculosis imitating ovarian carcinoma "special category".

    abstract::A case report, of a patient with peritoneal tuberculosis in whom the provisional diagnosis of ovarian carcinoma--"special category" was made is presented. As most gynecologists see hardly any cases of peritoneal tuberculosis nowadays, this possible diagnosis--which should always be considered--is reviewed. It illustra...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348509158214

    authors: Lachman E,Moodley J,Pitsoe SB

    更新日期:1985-01-01 00:00:00

  • Differential expression of T-helper cytokines in the peritoneal fluid of women with normal ovarian cycle compared with women with chronic anovulation.

    abstract:BACKGROUND:Estrogen and progesterone immunoregulate the genital environment by expression of cytokines and growth factors. OBJECTIVE:To investigate the pattern of expression of T-helper cytokines during the ovarian cycle compared with women with chronic anovulation resistant to clomiphene citrate. HYPOTHESIS:Expressi...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2003.00045.x

    authors: Omu AE,Al-Azemi MK,Makhseed M,Al-Oattan F,Ismail AA,Al-Tahir S,Al-Busiri N

    更新日期:2003-07-01 00:00:00

  • Curriculum development for a national cardiotocography education program: a Delphi survey to obtain consensus on learning objectives.

    abstract:OBJECTIVE:To define learning objectives for a national cardiotocography (CTG) education program based on expert consensus. DESIGN:A three-round Delphi survey. POPULATION AND SETTING:One midwife and one obstetrician from each maternity unit in Denmark were appointed based on CTG teaching experience and clinical obstet...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12662

    authors: Thellesen L,Hedegaard M,Bergholt T,Colov NP,Hoegh S,Sorensen JL

    更新日期:2015-08-01 00:00:00

  • Surgical management of abnormally invasive placenta: a retrospective cohort study demonstrating the benefits of a standardized operative approach.

    abstract:INTRODUCTION:Abnormally invasive placenta is a major cause of maternal morbidity and mortality. The aim of this study was to assess the effectiveness of a standardized operative approach performed by gynecological oncologists in the surgical management of abnormally invasive placenta. MATERIALS AND METHODS:We performe...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12768

    authors: Brennan DJ,Schulze B,Chetty N,Crandon A,Petersen SG,Gardener G,Perrin L

    更新日期:2015-12-01 00:00:00

  • A study on the effect of dehydroepiandrosterone sulfate on so-called cervical ripening.

    abstract::Dehydroepiandrosterone sulfate (DHAS) is now used for a dynamic test of placental function by many obstetricians. While practicing this test, the authors found that DHAS markedly promoted so-called "cervical ripening". To study this problem, DHAS of 50 or 100 mg in multiple doses were injected into 132 Japanese pregna...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347809156518

    authors: Mochizuki M,Honda T,Deguchi M,Morikawa H,Tojo S

    更新日期:1978-01-01 00:00:00

  • Fetal exposure to tobacco smoke products: a comparison between self-reported maternal smoking and concentrations of cotinine and thiocyanate in cord serum.

    abstract:BACKGROUND:The objective of the study was to assess the relationship between maternal smoking habits and biomarkers of tobacco smoke measured in cord serum. METHODS:The study population comprised 202 mothers, 42 daily smokers, 24 occasional smokers and 136 nonsmokers. Information on maternal smoking habits was collect...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349609055025

    authors: Nafstad P,Kongerud J,Botten G,Urdal P,Silsand T,Pedersen BS,Jaakkola JJ

    更新日期:1996-11-01 00:00:00

  • The added predictive value of biphasic events in ST analysis of the fetal electrocardiogram for intrapartum fetal monitoring.

    abstract:OBJECTIVE:To study the predictive value of biphasic ST-events for interventions for suspected fetal distress and adverse neonatal outcome, when using ST-analysis of the fetal electrocardiogram (FECG) for intrapartum fetal monitoring. DESIGN:Prospective cohort study. SETTING:Three academic hospitals in Sweden. POPULA...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/aogs.12548

    authors: Becker JH,Krikhaar A,Schuit E,Mårtendal A,Maršál K,Kwee A,Visser GH,Amer-Wåhlin I

    更新日期:2015-02-01 00:00:00

  • Elevated concentrations of interleukin-6 in intra-amniotic infection with Ureaplasma urealyticum in asymptomatic women during genetic amniocentesis.

    abstract:BACKGROUND:Intra-amniotic infection is an important cause of preterm delivery and interleukin-6 (IL-6) determination was recently applied for identification of microbial invasion of the amniotic cavity. Our aim was to determine the levels of IL-6 in culture-positive amniotic fluids at genetic amniocentesis and to evalu...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Bashiri A,Horowitz S,Huleihel M,Hackmon R,Dukler D,Mazor M

    更新日期:1999-05-01 00:00:00

  • Pancreatic beta-cell function and fetal growth in gestational impaired glucose tolerance.

    abstract:OBJECTIVE:To investigate the metabolic phenotype and pregnancy outcomes of gestational impaired glucose tolerance (IGT) defined by isolated hyperglycemia during an oral glucose tolerance test (OGTT). DESIGN:Retrospective cohort study. SETTING:University referral hospital. POPULATION:A total of 4,789 women were scree...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349.2010.487091

    authors: Miyakoshi K,Tanaka M,Saisho Y,Shimada A,Minegishi K,Kim SH,Asai S,Itoh H,Yoshimura Y

    更新日期:2010-06-01 00:00:00

  • Use of uterine electromyography to diagnose term and preterm labor.

    abstract::Current methodologies to assess the process of labor, such as tocodynamometry or intrauterine pressure catheters, fetal fibronectin, cervical length measurement and digital cervical examination, have several major drawbacks. They only measure the onset of labor indirectly and do not detect cellular changes characteris...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0412.2010.01031.x

    authors: Lucovnik M,Kuon RJ,Chambliss LR,Maner WL,Shi SQ,Shi L,Balducci J,Garfield RE

    更新日期:2011-02-01 00:00:00

  • Clinical profile of menopausal insomniac women referred to sleep laboratory.

    abstract:OBJECTIVE:The primary purpose of this study was to assess the overall clinical profile of menopausal women complaining of insomnia who were referred to a sleep laboratory. METHODS:A total of 206 menopausal women who had complaints related to insomnia were interviewed. Each participant completed a questionnaire in orde...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016340902777509

    authors: Hachul H,Brandão Lde C,Bittencourt LR,D'Almeida V,Andersen ML,Baracat EC,Tufik S

    更新日期:2009-01-01 00:00:00

  • The modified Misgav-Ladach versus the Pfannenstiel-Kerr technique for cesarean section: a randomized trial.

    abstract:BACKGROUND:Modifications to the classic cesarean section technique described by Pfannenstiel and Kerr have been proposed in the last few years. The objective of this trial was to compare intraoperative and short-term postoperative outcomes between the Pfannenstiel-Kerr and the modified Misgav-Ladach (MML) techniques fo...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.0001-6349.2005.00631.x

    authors: Xavier P,Ayres-De-Campos D,Reynolds A,Guimarães M,Costa-Santos C,Patrício B

    更新日期:2005-09-01 00:00:00

  • Randomized, prospective, double-blind comparison of abdominal and vaginal hysterectomy in women without uterovaginal prolapse.

    abstract:BACKGROUND:To determine under controlled conditions whether there are significant differences in the duration of hospitalization and recovery between abdominal and vaginal hysterectomy for indications other than uterovaginal prolapse. METHOD:In a two-center prospective, double-blind randomized trial, 36 women with dys...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1034/j.1600-0412.2003.00115.x

    authors: Miskry T,Magos A

    更新日期:2003-04-01 00:00:00