Abstract:
INTRODUCTION:The objective of this study was to assess the effectiveness and potential benefits of the use of long-acting recombinant follicle-stimulating hormone (FSH) in a random-start protocol for fertility preservation in women with cancer. MATERIAL AND METHODS:This is a retrospective before-and-after study performed between February 2013 and December 2015 in women who underwent ovarian hyperstimulation for oocyte cryobanking using a random-start approach. In the first part of the study period, the women were treated with daily recombinant FSH whereas in the second part the stimulation was initiated with long-acting recombinant FSH. The primary aim of the study was to compare the number of oocytes stored in the two study periods. In all, 140 women were ultimately selected. RESULTS:Compared with daily recombinant FSH, the use of the long-acting compound was associated with a reduced number of injections (12.5 ± 3.5 vs. 16.4 ± 0.3; p < 0.001) and a longer duration of stimulation (11.4 ± 1.9 vs. 10.6 ± 1.9, p = 0.01). Conversely, the number of oocytes collected (13.7 ± 9.5 vs. 11.3 ± 7.0, p = 0.10) as well as those cryopreserved (11.0 ± 8.0 vs. 9.5 ± 5.8, p = 0.21) did not differ. CONCLUSIONS:The use of long-acting recombinant FSH in random-start protocols for fertility preservation appears to be a valuable option.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Sarais V,Paffoni A,Pagliardini L,Filippi F,Martinelli F,Mangili G,Candiani M,Papaleo Edoi
10.1111/aogs.13146subject
Has Abstractpub_date
2017-08-01 00:00:00pages
949-953issue
8eissn
0001-6349issn
1600-0412journal_volume
96pub_type
杂志文章abstract:OBJECTIVE:To analyze compensation claims with neurological sequela or death following alleged birth asphyxia. DESIGN:A cohort study. SETTING:A nationwide study in Norway. SAMPLE:All claims made to The Norwegian System of Compensation to Patients (NPE) concerning sequela related to alleged birth asphyxia, between 199...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12276
更新日期:2014-02-01 00:00:00
abstract::Three cases with metastasized choriocarcinoma are reported. The basic chemotherapeutic regimen was methotrexate and actinomycin D, combined with cyclophosphamide or vinblastine. Surgery was used in the treatment of both primary and metastatic lesions. The chief indications for hysterectomy arise when chemotherapy has ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348409155520
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:To compare maternal and neonatal outcomes of term large for gestational age (LGA) pregnancies and adequate for gestational age (AGA) pregnancies. DESIGN:Retrospective analysis. SETTING:Large university research medical center. POPULATION:All term singleton LGA (birthweight ≥ 90th percentile) and AGA pregna...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0412.2012.01412.x
更新日期:2012-07-01 00:00:00
abstract::By employing an ammonium sulphate precipitation technique, previous studies have shown circulating immune complexes (cIC) in an increased proportion of women using oral contraceptives, as compared with non-users. The pathogenicity of cIC is well established, as deposition in organs may lead to activation of the comple...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348709004147
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To assess the contribution of non-medical factors to actual mode of delivery in a setting with high cesarean rates. DESIGN:Follow-up survey. SETTING:University department of obstetrics and gynecology. SAMPLE:Women with singleton pregnancies (n = 453) where there was no awareness of medical contradictions t...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12466
更新日期:2014-10-01 00:00:00
abstract::In a double-blind, randomized study, 50 patients undergoing conization were treated with either lysine-vasopressin (LVP) or its longer-acting analogue Glypressin. Bleeding during the operation and side effects were studied. The hemostatic effect appeared better with LVP than with Glypressin. One postoperative bleeding...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016348609161488
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To assess the occurrence of spontaneous abortion, comparing two different data sources. To estimate the rate of spontaneous abortion over a 2-year period, and examine potential predictors of the risk for incident spontaneous abortion. METHODS:We used interview data from a population-based prospective cohort ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340500494887
更新日期:2006-01-01 00:00:00
abstract::From January 1984 to October 1986, a total of 185 prenatal diagnostic procedures were performed, viz. 120 chorionic villus samplings, 42 fetal blood samplings, 12 skin biopsies and 11 tumor biopsies. All procedures were performed under continuous ultrasound guidance. The methods are described, and indications for each...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348709015728
更新日期:1987-01-01 00:00:00
abstract:INTRODUCTION:Approximately 85% of vaginal deliveries are accompanied by perineal trauma. The objective of this trial was to compare the incidence of perineal trauma after primary delivery of either the anterior or posterior shoulder during vaginal delivery. MATERIAL AND METHODS:This was a randomized single-blinded tri...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aogs.12914
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:Aim of the study was to assess the behavior of factor VII by commercial amidolytic assay in smoking and non-smoking pregnant women, and to compare this with the earlier reported factor VII:C levels during pregnancy and to discuss the role of F VII:Am with regard to thromboembolic complication in smoking pregn...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349709047819
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE:To demonstrate that panniculectomy in obese gynecologic oncology patients undergoing surgical gynecologic procedures reduces operative time, gives better surgical exposure and does not increase the number of operative complications. METHODS:A retrospective review of 90 patients who had panniculectomy at the ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00466.x
更新日期:2005-07-01 00:00:00
abstract::The concordance between measurements of total intra-uterine volume (parallel planimetric area method) and symphysis fundus height and the efficacy of these measurements in predicting birthweight by centile range was prospectively investigated in a blind study of 81 measurement sets in 74 women in the third trimester o...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348709103650
更新日期:1987-01-01 00:00:00
abstract::In 64 pregnant women admitted to hospital because of threatened abortion the prognostic value of estradiol-17-beta, estriol and human placental lactogen (HPL) in serum was examined. The hormones were determined by radioimmunoassay. Blood samples were taken at regular intervals during admission to hospital and subseque...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347909154597
更新日期:1979-01-01 00:00:00
abstract::Using standardized laparoscopy technique, fluid was aspirated from the pouch of Douglas, from the Fallopian tubes and from ovarian cysts in 85 cases with clinical diagnosis of pelvic inflammatory disease (PID). The concentration of doxycycline in the aspirates was measured after oral ingestion of 200 mg of doxycycline...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016347809155893
更新日期:1978-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to study whether the associations of maternal body mass index with offspring birthweight and placental weight differ by maternal diabetes status. MATERIAL AND METHODS:We performed a population study of 106 191 singleton pregnancies by using data from the years 2009-2012 in the Me...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12947
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the contribution of different subfertility treatments to the number of multiple pregnancies in a subfertile population. DESIGN:A prospective cohort study between January 2002 and December 2006. SETTING:A subfertility clinic in a large regional training hospital in the Netherlands. POPULATION:A ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349.2010.498495
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Intra-amniotic infection is an important cause of preterm delivery and interleukin-6 (IL-6) determination was recently applied for identification of microbial invasion of the amniotic cavity. Our aim was to determine the levels of IL-6 in culture-positive amniotic fluids at genetic amniocentesis and to evalu...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:There has been a rise in the prevalence of large newborns over a few decades in many parts of the world. There is ample evidence that fetal macrosomia is associated with increased risk of complications both for the mother and the newborn. In current obstetrics, the macrosomic fetus represents a frequent clin...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1080/00016340801899289
更新日期:2008-01-01 00:00:00
abstract::Using the registration of all pregnant women living within a particular geographical district of Copenhagen the risk of spontaneous abortion has been calculated by means of a decremental method. A total of 3,042 pregnancies were registered and the total risk of spontaneous abortion was calculated at 10 per cent. In 43...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348009154629
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:The purpose of the study was to evaluate the immediate outcome and complications of the tension-free vaginal tape (TVT) and laparoscopic mesh colposuspension (LC) procedures in the treatment of female stress urinary incontinence (SUI). METHODS:One hundred and twenty-eight patients suffering from urodynamica...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:To study the effect of hysterectomy or levonorgestrel-releasing intrauterine system (LNG-IUS) on premenstrual symptoms in women treated for menorrhagia. DESIGN:Secondary analysis of a randomized controlled trial. SETTING:Five university hospitals in Finland. SAMPLE:A cohort of 236 women, aged 35-49 years (...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0412.2011.01340.x
更新日期:2012-03-01 00:00:00
abstract::A cancer registry cohort of 16,704 cases of invasive carcinoma of the uterine cervix and 56,116 cases of in situ carcinomas of the uterine cervix was followed up and second new primary cancers were recorded. The invasive carcinomas contributed 127,118 woman-years at risk and the in situ carcinomas contributed 453,362 ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349009006163
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To study stillbirths and neonatal mortality in the postterm period. DESIGN:Register study of information obtained from the Swedish Medical Birth Registry (MBR), National Board of Health and Welfare, Stockholm. METHODS:Singleton pregnancies with deliveries occurring between 1982 and 1991 were selected involv...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016349709024606
更新日期:1997-08-01 00:00:00
abstract::During routine ante-natal testing during the period 1953-73 anti-c was found in the serum of 63 women. Twenty-four of them had received blood transfusion previously and of these 22 were multigravidae. In 39 women pregnancies alone were responsible for the immunization. The anti-c titres of the 42 women giving birth to...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347709162118
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:To evaluate the effects of L-arginine (ARG) infusion, the nitric oxide as substrate, on the utero-placental circulation at third trimester. METHODS:Three groups of nine pregnant women each were infused i.v. with 30 g ARG, for 30 minutes. One group served as control, and the two remnants were composed by pat...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016349609047088
更新日期:1996-03-01 00:00:00
abstract::Maternal Hb levels during the third trimester were studied in relation to certain maternal and fetal parameters in 877 apparently normal pregnancies. Low Hb levels at term were closely associated with increased frequency of newborns in the heavy weight-for-date group. Conversely, high maternal Hb levels were closely a...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348409155506
更新日期:1984-01-01 00:00:00
abstract::Uterine activity was measured quantitatively during subsequent labor after prostaglandin E2 gel (PGE2). Thirty primigravidae with a low Bishop score were included in this randomized double-blind study. Fewer women who received PGE2 required subsequent surgical induction. The pattern of uterine activity was different. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016348509154683
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Treatment of menorrhagia by heat-destruction of the endometrium, intended to be an alternative to hysterectomy, was investigated in an experimental study. METHOD:A specially designed catheter (CavatermTM) with a silicone balloon containing a self-regulating containing heating element is inserted into the ut...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016349609033325
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:The objective of the study was to assess the relationship between maternal smoking habits and biomarkers of tobacco smoke measured in cord serum. METHODS:The study population comprised 202 mothers, 42 daily smokers, 24 occasional smokers and 136 nonsmokers. Information on maternal smoking habits was collect...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349609055025
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Current health policies advocate patient participation in treatment decision-making. Objective. To explore whether role preferences among women with urinary incontinence (UI) change depending on the treatment decision-making context. We also explore what factors are associated with role preferences and chang...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340701622310
更新日期:2007-01-01 00:00:00