Early changes in flow cytometric DNA profiles induced by californium-252 neutron brachytherapy in squamocellular carcinomas of the uterine cervix.

abstract：:Circulating tumor cells (CTCs) represent a potential non-invasive substitute for real-time tissue biopsy. Moreover, detection of CTCs in breast cancer patients has been reported as a strong prognostic factor. Biomarkers on CTCs have been analysed and correlated to tissue biopsies from breast cancer patients. Discordan...

journal_title：Neoplasma

authors： Bystricky B,Mego M

更新日期：2016-01-01 00:00:00

abstract：:Cancer cells share numerous characteristics with pluripotent stem cells which develop normally, contributing to the tumor cell plasticity. So we investigated the effect of human embryonic germ cells (hEGCs) on SKOV3 cells. We examined the efficacy of hEGCs through coculturing SKOV3 with hEGCs, detecting tunel apoptosi...

journal_title：Neoplasma

authors： Song X,Kong B,Li D,Yang Q

更新日期：2009-01-01 00:00:00

abstract：:The expression of cytokeratins 7, 8, 14, 18, 19 and vimentin was examined in 100 cases of ductal invasive breast carcinomas. While the predominantly diffuse immunohistological positivity of simple epithelia cytokeratins 7 (in 93), 8 (in 100), 18 (in 100) and 19 (in 97) cases represents a constant feature of these tumo...

journal_title：Neoplasma

authors： Rejthar A,Nenutil R

更新日期：1997-01-01 00:00:00

abstract：:Ovarian cancer is the most lethal gynecologic malignancy in women with an increasing number of cases worldwide. Chemoresistance is the main obstacle for ovarian cancer treatment during clinical therapy. Previous studies found that programmed cell death 1 ligand 1 (PD-L1) was associated with chemoresistance of cancer. ...

journal_title：Neoplasma

authors： Zuo Y,Zheng W,Liu J,Tang Q,Wang SS,Yang XS

更新日期：2020-01-01 00:00:00

abstract：:The Carr-Zilber strain of Rous sarcoma virus is highly oncogenic for adult monkeys of the species Macaca mulata. In the present study, we examined some characteristics of tumor growth when the tumor either regressed or progressed until it killed its host. We followed the kinetics of antibody formation to antigens code...

journal_title：Neoplasma

authors： Adgighitov FI,Gubeladze DA,Lapin BA,Hlozánek I,Sovová V,Cerná H

更新日期：1980-01-01 00:00:00

abstract：:In the presented study we analysed the effect of histone deacetylase inhibitors (HDACi) suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) on human plasma cell leukemia (PCL) cell line UHKT-944 in the presence of bone marrow microenvironment (BMM). For the analysis, the cells were cultured alone, with bone...

journal_title：Neoplasma

authors： Burianova I,Kuzelova K,Mitrovsky O,Spicka I,Stockbauer P,Zackova M

更新日期：2017-01-01 00:00:00

abstract：:Projections for the incidence of all and selected major sites of cancer in the cities of Cracow and Bratislava were constructed for each year of the period 1978-1982 on the basis of data observed in the years 1968-1977. More or less increasing of unchanging trends were predicted for the malignant neoplasms of bladder,...

journal_title：Neoplasma

authors： Pawłega J,Plesko I,Dimitrova E

更新日期：1982-01-01 00:00:00

abstract：:During the years 1973-1987, 75 patients were irradiated for brain metastases of unknown origin at the Institute of Oncology in Ljubljana. Of these, 35 (47%) were previously treated by surgery: Metastases were completely removed in 22 patients and partially in 7, whereas biopsy alone was performed in 6 patients. Based ...

journal_title：Neoplasma

authors： Debevec M

更新日期：1990-01-01 00:00:00

abstract：:Effect of pentoxifylline (PTX) on vincristine (VCR) resistance of multidrug resistant L1210/VCR mouse leukemic cell line was studied. Reversal effect of PTX (in concentration 50-150 mg/l) on vincristine resistance, i.e. potentiation of vincristine cytotoxicity on L1210/VCR cells by PTX was found. PTX alone in the abov...

journal_title：Neoplasma

authors： Breier A,Barancík M,Stefanková Z,Uhrík B,Tribulová N

更新日期：1994-01-01 00:00:00

abstract：:Pyruvate dehydrogenase kinase 1 (PDHK1) and carbonic anhydrase IX (CAIX) are some of the most hypoxia-inducible proteins associated with tumors, implicated in glucose metabolism and pH regulation, respectively. They both appear to be necessary for model tumor growth, and their high level of expression in human tumors ...

journal_title：Neoplasma

authors： Kery M,Oravcova N,Radenkovic S,Iuliano F,Tomaskova J,Golias T

更新日期：2018-12-10 00:00:00

abstract：:The oral cavity is continually exposed to various traumas due to the effect of thermal, mechanical and chemical stimuli, which when accompanied by inflammatory states may promote the growth of neoplastic changes. Numerous studies have revealed a correlation between the expression of p53 and Bcl-2 proteins and the prog...

journal_title：Neoplasma

authors： Sulkowska M,Famulski W,Chyczewski L,Sulkowski S

更新日期：2001-01-01 00:00:00

abstract：:Podoplanin (D2-40) was shown to be expressed in cancer-associated fibroblasts (CAFs) of various malignancies. The study aimed at examining its impact on angiogenesis and lymphangiogenesis markers in invasive ductal carcinoma of the breast (IDC). The studies were performed on 104 archival cases of IDC using immunohisto...

journal_title：Neoplasma

authors： Pula B,Wojnar A,Witkiewicz W,Dziegiel P,Podhorska-Okolow M

更新日期：2013-01-01 00:00:00

abstract：:Possibilities of combined radioprotection, using preirradiation WR-2721 administration and post- or preirradiation Broncho-Vaxom administration in lethally whole-body gamma-irradiated mice were investigated. Combined modality treatments were more effective than individual treatments alone. The ameliorative influence o...

journal_title：Neoplasma

authors： Macková NO,Fedorocko P

更新日期：1995-01-01 00:00:00

abstract：:Recent studies have shown an indirect link between platelet count and blood vessel metastasis, but this association with lymphatic vessels metastasis has not been established in NSCLC. So we investigated whether an association exists between preoperative platelet count and lymph node metastasis in NSCLC patients. Betw...

journal_title：Neoplasma

authors： Liu HB,Gu XL,Ma XQ,Lv TF,Wu Y,Xiao YY,Yuan DM,Li YF,Song Y

更新日期：2013-01-01 00:00:00

abstract：:Leukemia-associated phenotypes have been suggested to be a valuable tool for the detection of minimal residual disease in acute leukemia patients, as they allow to distinguish leukemic blasts from normal hematopoietic progenitor cells. The aim of the present study was to analyze the proportion of acute leukemia patien...

journal_title：Neoplasma

authors： Babusíková O,Glasová M,Koníková E,Kusenda J

更新日期：1996-01-01 00:00:00

abstract：:Inhibiting activity of blood serum was determined from the decrease of N-acetyl-hexosamine end groups of hyaluronic acid products released by testicular hyaluronidase. Maximum inhibition was observed within the region of pH from 6.5 to 6.8. Correlation between the serum concentration and its inhibiting effect on hyalu...

journal_title：Neoplasma

authors： Kolárová M

更新日期：1975-01-01 00:00:00

abstract：:The significance of CEA, AFP, HCG and SP1 determinations in 85 patients with ovarian cancer were analyzed from the point of view of evaluation of the clinical status of the patients. On the basis of the trials it was stated that a satisfactory correlation between the extension of the tumor and the serum CEA level was ...

journal_title：Neoplasma

authors： Pulay T,Csömör S,Mészáros K,Szarka G,Csabay L,Szinnyai A

更新日期：1987-01-01 00:00:00

abstract：:Weanling ICRC female mice were given syngeneic neonatal thymus graft under renal capsule and two weeks later whole-body gamma-radiation (group ITR). The findings on ITR were compared with three controls--untreated (C), thymus grafted (IT) and irradiated (IR). In ITR group 15/15 developed generalized neoplasms of retic...

journal_title：Neoplasma

authors： Pai SR,Sequeira B

更新日期：1985-01-01 00:00:00

abstract：:We report in this study that microRNA-584-3p (miR-584-3p) is related to the vasculogenic mimicry (VM) of human glioma cells. Unsurprisingly, the postoperative survival time was significantly prolonged in those glioma patients without VM phenomena compared with those with positive VM. miR-584-3p may function as a poten...

journal_title：Neoplasma

authors： Xu S,Zhang J,Xue H,Guo X,Han X,Li T,Guo X,Gao X,Liu Q,Li G

更新日期：2017-01-01 00:00:00

abstract：:The aim of the study was to evaluate the expression of activated mammalian rapamycin (mTOR) and its downstream effectors, phosphorylated p70 ribosomal protein S6 kinase (p70S6K) and eukaryotic initiation factor 4E-binding protein 1 (4EBP1), in intrahepatic cholangiocarcinomas (ICC), in order to strengthen the rational...

journal_title：Neoplasma

authors： Wang Z,Zheng T,Wu Q,Wang J,Wu C,Wang J

更新日期：2012-01-01 00:00:00

abstract：UNLABELLED:microRNA-24 has been reported to participate in tumorgenesis and progression by several signaling pathways in various tumors. However, its potential as a serum diagnostic factor and predictive biomarker for esophageal squamous cell carcinoma (ESCC) has not been studied. In the present study, serum samples we...

journal_title：Neoplasma

authors： Dong W,Li B,Wang Z,Zhang Z,Wang J

更新日期：2015-01-01 00:00:00

abstract：:All cases of Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL) reported to the Kuwait Cancer Registry between 1980-1989 were analyzed. Age specific and age standardized incidence rates were calculated for Kuwaiti and non-Kuwaiti males and females for the two periods of 1980-1984 and 1985-1989, and compared to de...

journal_title：Neoplasma

authors： al-Bahar S,Pandita R,al-Bahar E,al-Muhana A,al-Yaseen N

更新日期：1996-01-01 00:00:00

abstract：:Cancer is a complex disease with interactions between normal and neoplastic cells. Since current therapies for cancer largely rely on drugs or radiation that kill dividing cells or block cell division, these treatments may have severe side effects on normal proliferating cells in patients with cancer. Recently, immuno...

journal_title：Neoplasma

authors： Zhou LT,Liu FY,Li Y,Peng YM,Liu YH,Li J

更新日期：2012-01-01 00:00:00

abstract：:The possible association between cigarette smoking and the risk of benign breast disease (BBD) was assessed in a case-control study conducted in Gdańsk, Poland, between 1990 and 1994. The study compared 160 women with newly diagnosed BBD admitted to the Gdańsk Cancer Outpatients Clinic and 160 controls, women from out...

journal_title：Neoplasma

authors： Dziewulska-Bokiniec A

更新日期：1995-01-01 00:00:00

abstract：:Zinc finger protein 139(ZNF139), a member of zinc finger protein family, is a transcription factor. Our previous research showed ZNF139 was overexpressed in gastric cancer cells. The purpose of present study is to explore impact and mechanism of ZNF139 on metastasis by regulating invasive ability of gastric cancer cel...

journal_title：Neoplasma

authors： Li Y,Tan BB,Zhao Q,Fan LQ,Wang D,Liu Y

更新日期：2014-01-01 00:00:00

abstract：:Cysteine proteinases cathepsin (Cath) B and L and their endogenous inhibitors stefin (Stef) A and B concentrations were measured using a quantitative immunosorbent assay (ELISA; KRKA d.d., Novo mesto, Slovenia) in serum samples from 35 patients with primary and 7 patients with recurrent squamous cell carcinoma of the ...

journal_title：Neoplasma

authors： Strojan P,Budihna M,Smid L,Svetic B,Vrhovec I,Skrk J

更新日期：2001-01-01 00:00:00

abstract：:The analysis of DNA methylation patterns in circulating cell-free DNA in body fluids is an analyte of great interest in clinical research. Downstream of Kinase (DOK) proteins represent a multigenic family of adaptors that includes negative regulators of immune cell signaling and plays important roles in signaling, cel...

journal_title：Neoplasma

authors： Heidarizadi A,Salimi M,Mozdarani H

更新日期：2020-07-01 00:00:00

abstract：:The cytostatic activity of 2-thio-4-hydrazinouracil (THU) on some transplantable tumors has been studied. A strong effect of this compound (between 60% and 100% suppression) has been found in the case of Myeloma P-8 (MOPC-21) and Sarcoma 180 (Crocker). A less pronounced effect has been observed on Yoshida sarcoma, whi...

journal_title：Neoplasma

authors： Golovinsky EV,Emanuilov EA,Spassovska NC,Spassov AV

更新日期：1975-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it carries a poor prognosis. Clarifying the pathologic mechanisms of this disease will be beneficial for the diagnosis and treatment of HCC. LncRNA MEG8 is involved in several tumors but its role in HCC progression remains unknown. This st...

journal_title：Neoplasma

authors： Lou J,Yan W,Li QY,Zhu AK,Tan BQ,Dong R,Zou XZ,Liu T

更新日期：2020-11-05 00:00:00

abstract：:The aim of our study was to evaluate the efficacy of oral clodronate supplementing systemic therapy and/or palliative irradiation in 91 patients with painful bone metastases. Clodronate was administered at a daily dose of 1600-3200 mg for a median of 11 months (range 3--36 months). Partial or complete pain relief was ...

journal_title：Neoplasma

authors： Serkies K,Jereczek-Fossa B,Badzio A,Jassem J

更新日期：1999-01-01 00:00:00