Abstract:
INTRODUCTION:There are few epidemiological studies on candidaemia in the paediatric population in Spain. We sought to determine the epidemiology of candidaemia in these patients. METHODS:Prospective, observational and multicentre study in 44 Spanish hospitals. All candidaemia episodes in paediatric patients from 0 to 15 years old between January 2009 and February 2010 were studied. RESULTS:There were 197 episodes and 200 species were isolated. The most frequent species was Candida parapsilosis sensu stricto (43%), followed by C. albicans (36%), C. tropicalis (6%), C. orthopsilosis, and C. glabrata (4%) respectively. C. albicans was the most prevalent in newborns, and C. parapsilosis was most frequent in the other age groups. As regards the regions of Spain, C. albicans was most prevalent in patients from Catalonia, the Balearic Islands and Canary Islands, and C. parapsilosis in patients from Andalusia, Castilla-León, Galicia, Valencia, and Madrid. The rate of resistance to fluconazole was 1.5% (4.1% with the new species-specific Clinical and Laboratory Standards Institute [CLSI] criteria). Fluconazole resistance was lower in neonates than the other age groups. The Neonatal Wards were the areas with most episodes (31.5%). In the multivariate analysis, the variables associated independently with candidaemia due to C. albicans were: catheter (OR: 5.967; 95% CI: 1.614-22.057; P=.007) and prematurity (OR: 2.229; 95% CI: 1.141- 4.631; P=.020). CONCLUSIONS:The epidemiology of paediatric candidaemia varies between Spanish regions, but, globally, C. parapsilosis and C. albicans, are respectively, the first and second most frequently isolated species, and they show resistance rates to fluconazole of less than 5%.
journal_name
Enferm Infecc Microbiol Clinjournal_title
Enfermedades infecciosas y microbiologia clinicaauthors
García-Rodríguez J,Cantón E,Pemán J,Alvarez M,Ezpeleta G,Gómez-Nieto A,Iglesias I,Martín-Mazuelos E,Ramírez-de Ocariz I,Rezusta A,Royo-García G,Grupo de Estudio FUNGEMYCA.doi
10.1016/j.eimc.2012.09.018subject
Has Abstractpub_date
2013-06-01 00:00:00pages
363-8issue
6eissn
0213-005Xissn
1578-1852pii
S0213-005X(12)00363-1journal_volume
31pub_type
杂志文章,多中心研究abstract::The genera Phlebovirus transmitted by Diptera belonging to the Psychodidae family are a cause of self-limited febrile syndrome in the Mediterranean basin in summer and autumn. Toscana virus can also cause meningitis and meningoencephalitis. In Spain, Toscana, Granada, Naples, Sicily, Arbia and Arrabida-like viruses ha...
journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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abstract::Highly active antiretroviral therapy has helped to improved control of the HIV infection, and has led to a progressively older population with the infection having a life expectancy quite similar to that of the general population. On the other hand, it is also known that HIV infection, even in patients with undetectab...
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 共识发展会议,杂志文章,实务指引
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abstract:BACKGROUND:Diarrhea associated with Clostridium difficile is a health care problem of growing importance in the last few years specially in the hospital environment. The epidemiologic data and factors associated with this disease have not, to date, been sufficiently studied in Spain. METHODS:The cases of diarrhea asso...
journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 共识发展会议,杂志文章,实务指引,评审
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,多中心研究
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abstract:BACKGROUND:HIV infection and parenteral drug abuse (PDA) are frequently associated conditions. Both are at increased risk of developing specific types of Candida infections. Localized CNS infection is an exceptional finding. METHODS:We report two cases of meningitis in PDA due to Candida albicans--one of them HIV posi...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章,评审
doi:
更新日期:1993-05-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
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doi:
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journal_title:Enfermedades infecciosas y microbiologia clinica
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更新日期:1992-01-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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doi:
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journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
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更新日期:1995-02-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
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更新日期:2007-01-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
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journal_title:Enfermedades infecciosas y microbiologia clinica
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更新日期:2008-12-01 00:00:00
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journal_title:Enfermedades infecciosas y microbiologia clinica
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更新日期:2012-10-01 00:00:00
abstract::Telaprevir is an extremely potent antiviral drug. However, as with other direct-acting antiviral agents against the hepatitis C virus (HCV), this potency can be compromised by the rapid emergence of resistance mutations. This phenomenon is favored by the high rate of HCV replication, the lack of corrective activity to...
journal_title:Enfermedades infecciosas y microbiologia clinica
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doi:10.1016/S0213-005X(13)70121-6
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:Diagnosis of HSV-1 keratitis (HK) is frequently based on clinical findings. Invasive specimens (corneal scrapings, biopsies) are required for microbiological diagnosis. METHODS:Corneal scrapings and conjunctival swabs were collected on patients with/without clinical suspicion of HK from 2007 to 2012. RES...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
doi:10.1016/j.eimc.2013.07.005
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital. METHODS:A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hos...
journal_title:Enfermedades infecciosas y microbiologia clinica
pub_type: 杂志文章
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更新日期:2021-01-12 00:00:00