Abstract:
BACKGROUND:Rathke's cleft cyst (RCC) with significant squamous and/or stratified epithelium including smooth transition from single cuboidal to squamous epithelium (tRCC) is rare and possibly represents an intermediate form to craniopharyngioma. METHODS:Twelve patients with histologically confirmed tRCC were retrospectively investigated from a series of 167 cases of RCC and 96 cases of craniopharyngiomas. Clinical data were reviewed, and immunohistochemistry findings for cytokeratins and β-catenin were examined. RESULTS:All lesions were located in the sella turcica with marked extension to suprasellar cistern. Six of the 12 patients had suffered postoperative re-enlargement, and three of these six patients required more than two additional operations and irradiation. CAM5.2 was positive in the glandular epithelium in all tRCCs and focally positive in the squamous epithelium of all these tRCCs. 34βE12 was positive in the squamous epithelium in all tRCCs and focally positive in the glandular epithelium in all but one tRCC. The findings of cytokeratin expression of tRCCs were very similar to those of craniopharyngioma. β-Catenin showed nuclear translocation in five cases. All patients with nuclear translocation of β-catenin suffered postoperative re-enlargement. CONCLUSIONS:tRCC carries an extremely high risk of re-enlargement. Cytokeratin expression resembles that in craniopharyngioma, which might indicate a very close origin of these pathologies. Nuclear translocation of β-catenin may be related to the aggressive clinical course.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Ogawa Y,Watanabe M,Tominaga Tdoi
10.1007/s00701-012-1593-9subject
Has Abstractpub_date
2013-06-01 00:00:00pages
1069-75issue
6eissn
0001-6268issn
0942-0940journal_volume
155pub_type
杂志文章abstract::After clipping of intracranial aneurysms, postoperative vasospasm may occur remote from the distribution area of the artery and may cause death. The authors report two cases and give the clinical, neuroradiological, and neuroanatomical findings. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01773115
更新日期:1978-01-01 00:00:00
abstract::The present study is aimed at examining the therapeutic effect of Nicorandil on chronic vasospasm using beagle dogs subjected to a "two-haemorrhage" insult, as well as its dilatory effect on the PDA [phorbol-12,13 diacetate]-induced contraction of the canine basilar artery. 1. A total of 12 animals of either sex, weig...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01476428
更新日期:1994-01-01 00:00:00
abstract::In part I of this report, the CSF circulatory dynamics of autologous leucocytes labelled with indium-111 and injected in the subarachnoid space, in patients operated on for glioblastoma, were studied. In the Part II, a series of 11 patients with recurrent glioblastoma was studied for evaluating the efficacy of intrath...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406665
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Long-term survival of patients with recurrent gliomas depends on the extent of resection. Thus, the desirability of an intra-operative imaging modality that can augment the resection extension without affecting vital surrounding structures is more than obvious. It was the aim of the present study to evaluate...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0858-6
更新日期:2006-10-01 00:00:00
abstract::MRI is routinely used in the evaluation and management of patients with failed back surgery syndrome (FBSS). However, its value is unclear in the early detection of signs that can negatively affect that later course of surgical cases. The purpose of the present study is to describe the MR images of early postoperative...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01844746
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Orthostatic headache (OH) is a potential complication of lumbar drainage (LD) usage. The incidence and risk factors for OH with the use of lumbar drainage during endoscopic endonasal procedures have not been documented. OBJECTIVE:To investigate the incidence of post-procedure OHs associated with placement o...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3247-4
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The management of pineal cysts is still debatable, especially for asymptomatic incidental ones. For symptomatic cysts associated with hydrocephalus, the surgical management is mandatory and may include either classical microsurgical approaches to the pineal region or endoscopic trans-ventricular approaches i...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1849-z
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Catheter-assisted Guglielmi detachable coiling (CAGDC) is a technical option that was developed to allow the endovascular treatment of wide-necked aneurysms. We report upon our experiences of the CAGDC in treating aneurysms with an assessment of its efficacy and safety. METHODS:The effect of CAGDC of wide-n...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0881-7
更新日期:2006-10-01 00:00:00
abstract::Leptomeningeal cysts are commonly seen in children usually following trauma and associated with bulging leptomeninges at the site of fracture. Intradiploic leptomeningeal cyst is an important differential for an expansile lytic lesion in the bony calvarium especially in a patient with a previous history of trauma. Her...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2660-9
更新日期:2016-02-01 00:00:00
abstract::In addition to the high rate of shunt complications due to obstruction and infection there is a considerable number of undesirable side effects caused by excessive drainage of CSF. Four hundred shunt treated patients are analyzed for overdrainage signs: acute decompression symptoms produced by upward shifting of the b...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01774384
更新日期:1978-01-01 00:00:00
abstract::The ventriculographic findings of a severe ascending transtentorial herniation that occurred after shunting in an infant with a posterior fossa tumour are described. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405337
更新日期:1978-01-01 00:00:00
abstract::The authors present a case of cauda equina paraparesis due to compression by tabetic osteo-arthropathy. Diagnosis was confirmed by the typical clinical picture of tabes and by the history of a chancre 53 years earlier. Radiography of the spine showed vertibral osteo-arthropathy. Opaque contrast myelography showed comp...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01774757
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Clinical management after epidural steroid injections (ESI) of patients with radiculopathy secondary to a cervical disc herniation (CDH) is uncertain. This study aims to determine whether short-term arm pain alleviation following computed tomography-guided 'indirect' cervical ESI can predict the 1-month outc...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2997-8
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Brain arteriovenous malformations (AVMs) of the elderly have not received sufficient attention, given the increase in age of individuals in recent years. We therefore designed a retrospective study to clarify features of brain AVMs in this age group in comparison with their counterparts in the general popula...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-004-0346-9
更新日期:2004-10-01 00:00:00
abstract::70 patients were treated for spinal dural arteriovenous fistula in the same centre, during a period of 10 years. Conus medullaris and cauda equina syndromes were observed in all patients as the clinical stereotyped presentation. Diagnosis was based on myelography in the first instance and then on angiography. 40 patie...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01403601
更新日期:1989-01-01 00:00:00
abstract::Diffuse brain injury in rabbits was caused by injecting olive oil and saline into one internal carotid artery. In this report, the fourth of a series, the effects of this experimental brain injury on respiration and acid-base balance of blood are analyzed. The animals that withstood the injury best were those that had...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405898
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:Early repair of myelomeningocoele (MM) is associated with decreased morbidity and mortality. In sub-Saharan Africa, the peculiar harsh economic and social realities make late presentation, malnutrition and sepsis at presentation prevalent. As these factors may affect surgical repair, the aim of this study was...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-008-0002-x
更新日期:2008-09-01 00:00:00
abstract:INTRODUCTION:Navigated transcranial magnetic stimulation (nTMS) is increasingly used for preoperative mapping of motor function, and clinical evidence for its benefit for brain tumor patients is accumulating. In respect to language mapping with repetitive nTMS, literature reports have yielded variable results, and it i...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-017-3187-z
更新日期:2017-07-01 00:00:00
abstract::We investigated the role of plasminogen activators (PAs) and their inhibitor (plasminogen activator inhibitor-1, PAI-1) in human brain tumours. The amounts of urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA), and plasminogen activator inhibitor-1 (PAI-1), and the activity of u-PA a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050112
更新日期:1998-01-01 00:00:00
abstract::This study concerns 19 patients over 16 years of age with Moyamoya disease. Ten cases of intracranial haemorrhage, as the initial haemorrhagic event in patients aged from 21 to 55 (haemorrhagic group) and 9 cases of ischaemic events in 18- to 53-year-old patients (ischaemic group) were included. All haemorrhages were ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411056
更新日期:1996-01-01 00:00:00
abstract::The influence of moderately reduced arterial oxygen tension (aPO2 of about 45 Torr) on the metabolism and the blood flow of the brain was tested in 20 anaesthetized, artificially ventilated normotensive, normocapnic beagle dogs. It is demonstrated that the decrease in systemic oxygen delivery to the brain is countered...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01402057
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Infratentorial supracerebellar approach via microscope still has some limitations in resection of pineal region tumors. METHODS:The authors describe a purely endoscopic infratentorial supracerebellar approach for resection of pineal region tumors with matched air-driven arm and navigation. The lateral obliq...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2895-0
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Convection-enhanced delivery (CED) is a technique allowing local infusion of therapeutic agents into the central nervous system, circumventing the blood-brain or spinal cord barrier. OBJECTIVE:To evaluate the utility of nimustine hydrochloride (ACNU) CED in controlling tumor progression in an experimental s...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3123-2
更新日期:2017-05-01 00:00:00
abstract:AIM:To study the value of early (24 h) post-operative ACTH and serum cortisol as predictors of remission after transsphenoidal surgery in Cushing's disease. METHODS:We prospectively studied 44 patients who underwent transsphenoidal surgery for Cushing's disease between 1997 and 2005. The mean follow-up period of patie...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-007-1133-1
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:In terms of response to fractionated radiotherapy, metastatic brain tumors of certain origins are considered radioresistant. OBJECTIVE:To determine the influence of "radioresistant" histology on outcomes of brain metastases treated with radiosurgery. METHODS:Between 2001 and 2017, 121 patients with brain m...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-018-3726-2
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Pituitary apoplexy is a rare and life-threatening complication occurring in 0.6-10.5% of all cases of pituitary adenomas. Although the association between pituitary apoplexy and visual dysfunction has been recognized for a long time, the optimal management of this problem still remains controversial. The pur...
journal_title:Acta neurochirurgica
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s00701-009-0595-8
更新日期:2010-05-01 00:00:00
abstract::To understand the clinicopathology features of leptomeningeal dissemination of malignant gliomas, a total of 157 consecutive patients treated between 1978 and 1989 were analysed. Twenty-two patients (14%) were judged to have dissemination. In 20 patients, the dissemination was diagnosed antemortem. Eleven patients had...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01476415
更新日期:1994-01-01 00:00:00
abstract::The effect of acetazolamide on the cerebral blood flow was studied in gerbils with unilateral carotid ligation. According to the effect of ligation the animals were divided into three groups: first group-the reduction more than 70%, second-CBF reduction 30-70% and the third group-CBF reduction less than 30%. The effec...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411729
更新日期:1996-01-01 00:00:00
abstract::External continuous ventricular drainage (CVD) in patients suffering from obstructive hydrocephalus is being used in many neurosurgical centers as a routine procedure for the temporary relief of intracranial pressure. The results of this treatment have been insufficiently evaluated. In the present study two groups of ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406401
更新日期:1979-01-01 00:00:00
abstract::Malignant glioma presenting as an intracerebral haematoma is very rare. Two patients having malignant gliomas, initially presenting as intraparenchymal haematomas, are discussed. One patient survived, but the other patient rapidly deteriorated and died. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01407682
更新日期:1979-01-01 00:00:00