Abstract:
BACKGROUND:Brain arteriovenous malformations (AVMs) of the elderly have not received sufficient attention, given the increase in age of individuals in recent years. We therefore designed a retrospective study to clarify features of brain AVMs in this age group in comparison with their counterparts in the general population. METHODS:A retrospective study was performed, based on data for AVMs treated in Nara Medical University Hospital and affiliated hospitals over the past 13 years. The series included all cases of brain AVMs, except for pure dural AVMs, diagnosed from June 1989 to June 2003. A total of 175 patients were diagnosed as having an AVM during this period, including 32 patients more than 60 years old. Clinical features and effective treatment of brain AVMs in those over and under 60 were explored and outcome at 3 to 6 months after surgery was evaluated according to a modified neurological scale. FINDINGS:The most common mode of presentation was intracranial hemorrhage in both groups, and this was remarkable in the elderly. Epilepsy at presentation was less frequent in the elderly (P< 0.05). In the elderly group infratentorial lesions were encountered more frequently (P< 0.05). Good or excellent outcomes of surgery were accomplished in 82.6% of the non-elderly group, and in 69.6% of the elderly group. When restricted to the grades I or II of Spetzler and Martin (S & M) grading, postoperative neurological scores of both groups were significantly better than preoperative values (P < 0.01). In the grade III cases, the non-elderly demonstrated significant improvement after surgery (P <0.01), but the elderly did not. INTERPRETATION:Elderly patients with a brain AVM had clinical features of less frequent epileptic presentation and more frequent infratentorial lesions. It was suggested that surgery was acceptable in elderly patients with pallial AVMs of grade I and II. Surgery for grade III AVMs of the elderly remains to be clarified.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Hashimoto H,Iida J,Kawaguchi S,Sakaki Tdoi
10.1007/s00701-004-0346-9subject
Has Abstractpub_date
2004-10-01 00:00:00pages
1091-8; discussion 1098issue
10eissn
0001-6268issn
0942-0940journal_volume
146pub_type
杂志文章abstract::The authors report on four unusual cases of chronic adult hydrocephalus extracted from a large personal series of patients with hydrocephalic dementia. A syndrome resembling that of normal pressure hydrocephalus was due to the following aetiologies in these patients: Paget's disease of the skull, unruptured cerebral a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01808923
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:We used [F-18] FDG microPET imaging as part of a longitudinal study to investigate changes in the brain. METHODS:Glucose metabolism during the development of neuropathic pain after tibial and sural nerve transection (TST) model rats. MicroPET images were obtained 1 week before operation and then weekly for ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2415-7
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To analyse the intraoperative complications of a single neurosurgeon, with emphasis on devastating intraoperative incidents, and how they possibly could have been avoided. METHODS:All the patients operated upon by the author between 1986 and 2002, i.e. 252 patients with 270 craniotomies for 294 aneurysms, were...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0452-9
更新日期:2009-09-01 00:00:00
abstract::In 17 primary transnasal operations on Nelson tumours long-term results are assessed measuring ACTH plasma levels and performing regular neuroradiological controls. In small intrasellar adenomas only one recurrent ACTH elevation near to pretreatment levels without symptoms from tumour growth was observed after 10 year...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405437
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To establish the risk of recurrence in patients with chronic subdural hematoma (cSDH) on antithrombotic treatment (AT, i.e., antiplatelets and anticoagulants). Secondary end points were perioperative morbidity and mortality between groups (AT vs. no-AT group) and exploration if timing of resumption of AT trea...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3330-x
更新日期:2017-11-01 00:00:00
abstract::Stereotactic targeting of the postero-ventral pallidum (PVP) presents special challenges to the surgeon 1) The target is in intimate relation to the optic tract and the internal capsule. 2) Proper angulation of the trajectory is crucial to achieve optimal effects given the long craniocaudal extension of the PVP. 3) Th...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411480
更新日期:1996-01-01 00:00:00
abstract::In this paper, we discuss the results of a study by light microscope of the effect of permanent clipping or ligation on the intracranial arteries of 38 operation dogs and 7 control dogs. The findings obtained are: 1. In the cerebral arterial circle, necrosis could easily result from ordinary clipping or ligation becau...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405851
更新日期:1982-01-01 00:00:00
abstract::Recent studies on prognostic variables and the intensive care of head injuries enabled us to select 64 patients and administer a standard treatment protocol to prevent secondary brain injury. All the patients were in coma with a flexor motor pattern as the best response between 6 and 24 hours after the accident and/or...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01413271
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Dystonia has been treated well using deep brain stimulation at the globus pallidus internus (GPi DBS). Dystonia can be categorized as two basic types of movement, phasic-type and tonic-type. Cervical dystonia is the most common type of focal dystonia, and sequential differences in clinical outcomes between p...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2646-7
更新日期:2016-01-01 00:00:00
abstract::Incomplete cerebral ischaemia of 10 to 60 minutes duration was performed by reducing the perfusion pressure of completely isolated canine heads at brain temperatures of 37 and 32 degrees C. Complete cerebral ischaemia of the same duration was performed by complete stopping of the perfusion. The latency of recovery of ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02074501
更新日期:1982-01-01 00:00:00
abstract::Monostotic manifestation of fibrous dysplasia in the spine is exceedingly rare. We report the case of a 30 year-old woman suffering from slowly increasing low back pain. Radiologically a polycyclic, slightly gadolinium-enhancing, solitary lesion within the first lumbar vertebral body was detected. The lesion was remov...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0133-z
更新日期:2003-11-01 00:00:00
abstract::Being motor nerves neurinomas originating from ocular nerves are very rare, unless associated with neurofibromatosis. Authors describe two cases of oculomotor nerve i.e. third nerve, Schwann cell tumours. One of them presented as a cavernous sinus mass in a middle aged lady while the other was a middle aged man with a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050229
更新日期:1998-01-01 00:00:00
abstract::Cavernous malformations (CM) occur very rarely in the ventricular system. We report a patient with a rare location in the third ventricle who had intermittent headaches as the initial symptom. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-004-0393-2
更新日期:2005-01-01 00:00:00
abstract::We investigated 76 patients with known subarachnoid haemorrhage (SAH) in order to compare the results of angiography and non-invasive Doppler recordings of cerebral artery blood velocity in the diagnosis of cerebral vasospasm. One radiologist and one neurovascular surgeon assessed angiographic spasm visually on a four...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405268
更新日期:1989-01-01 00:00:00
abstract::The superficial middle cerebral veins (SMCVs) are large veins to drain the brain and therefore anatomical knowledge of them is important for neurosurgeons and neuroradiologists. In a patient with a ruptured blister aneurysm, we incidentally found during angiography an aberrant drainage of the SMCVs, which penetrated t...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-03838-z
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:To evaluate the clinical presentation, diagnostic and therapeutic management and outcome of 27 cases of post-traumatic thoracic outlet syndrome (PT TOS). METHODS:Retrospective chart analysis. RESULTS:Nineteen women and eight men were included in this study. Involvement in a traffic accident was the most co...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-011-1269-x
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:A number of different image-guided surgical techniques have been developed during the past decade. None of these methods can provide the surgeon with information about the dynamic changes that occur intra-operatively. MATERIAL AND METHOD:The first vertical open 0.5T MRI-scanner for intra-operative MRI-guide...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050325
更新日期:1999-01-01 00:00:00
abstract::An intensive experimental spinal cord impact trauma in rabbits led, after 90 minutes, to a significant increase of serotonin content in the segments of spinal cord at the injury epicentres. Adjacent segments showed normal values. It is suggested that the existing contradictory published data concerning the serotonin c...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405241
更新日期:1977-01-01 00:00:00
abstract::Fifty-one cases of posterior fossa haemangioblastoma have been seen in our department over a period of 23 years. Seven cases were associated with spinal cord lesions and one with a supratentorial lesion. There were 22 cases of Lindau's disease (43%). The onset was earlier and recurrences commoner than in isolated case...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02112026
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The association between external ventricular drainage (EVD) and aneurysm rerupture is still a controversial issue. We performed a systematic review and meta-analysis of published series reporting data of EVD placement in aneurysmal subarachnoid hemorrhage (SAH) with the aim to evaluate the relationship betwe...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00701-017-3124-1
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Surgical treatment of giant clinoidal meningiomas remains a challenging task for neurosurgeons. Here, we present details of the surgical techniques for the dissection of encased perforators. METHODS:The dissection of encased perforators is summarized as follows: (1) split the tumor above the encased arterie...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1750-9
更新日期:2013-08-01 00:00:00
abstract:OBJECT:The authors analyzed the cases of 163 patients with syringomyelia to assess the appropriate surgical procedure. METHODS:Depending on the aetiological factors and treatment considerations the series was classified into three groups. Group I were cases where there was no definite demonstrable aetiological factor;...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050038
更新日期:2000-01-01 00:00:00
abstract::Three cases of surgically treated non-neoplastic diseases of the sella (two arachnoid cysts and one empty sella) are reported. All three patients had visual deficits but no gross endocrine disturbances. The study of these three clinical cases and an analysis of the relevant literature suggest a possible unitary hypoth...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401097
更新日期:1977-01-01 00:00:00
abstract::The feline infusion model of brain edema was used to evaluate the pathophysiological effects of 0.6 ml infusions of autologous serum protein (66%), human serum protein (66%), human glioma cyst fluid and a tissue culture medium (TCM) on the structure and function of the forebrain white matter. These infusions increased...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02112037
更新日期:1993-01-01 00:00:00
abstract::First described on pre-B leukemia cells, the common acute lymphoblastic leukemia antigen (cALLa) is also expressed on glioma cells in vitro. Its identity to neutral endopeptidase (NEP) (E.C.3.24.11) was corroborated by our finding that cALLa positive glioma cells had NEP activity. To study cALLa/NEP distribution on gl...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401105
更新日期:1992-01-01 00:00:00
abstract::The growth of a small arteriovenous angioma over a period of almost 18 years in a 20 year old patient has been proved by arteriography. This case is added to 29 cases previously published in the literature. The authors do not readily accept the theory of autochthonous growth, but prefer secondary or "pseudo-growth". I...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405394
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:In case of suspected normal pressure hydrocephalus, MRI is performed systematically and can sometimes highlight an obstruction of the flow pathways of the CSF (aqueductal stenosis or other downstream obstruction). It seems legitimate for these patients to ask the question of a treatment with endoscopic third...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-03932-2
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Increasingly, biomarkers have been identified that correlate with improved overall and progression-free survival (OS and PFS) in glioblastoma, including MGMT methylation status and mutations in the IDH1 gene. In this study, we investigated the clinical and biological factors associated with long-term surviva...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2928-8
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:Melanotic neuroectodermal tumor of infancy (MNT1) is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, and rapidly growing that develops during the first year of life. It most commonly arises from the maxilla, the cranial vault, and the mandible. Early diagnosis and radical s...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,随机对照试验,评审
doi:10.1007/s00701-009-0472-5
更新日期:2010-05-01 00:00:00
abstract::We report a 2.5-year-old boy with Saudi variant of multiple sulfatase deficiency (MSD or Austin's disease). He presented with the features of cervical cord compression and a severe form of hydrocephalus. The former was due to a thickened posterior arch of the atlas and the latter from a narrow foramen magnum and menin...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401468
更新日期:1994-01-01 00:00:00