Abstract:
:To understand the clinicopathology features of leptomeningeal dissemination of malignant gliomas, a total of 157 consecutive patients treated between 1978 and 1989 were analysed. Twenty-two patients (14%) were judged to have dissemination. In 20 patients, the dissemination was diagnosed antemortem. Eleven patients had neurological deficits due to dissemination, whereas the other 9 without these had CT or myelographic evidence of dissemination. The peak incidence of dissemination was seen in the first and second decades of life. The mean age of 22 patients with dissemination was 31 years, significantly lower than that (44.5 years) of patients without dissemination. Fifteen patients developed dissemination within one year after diagnosis (early dissemination), 60% of them were less than 30 years of age. All patients with late dissemination (more than one year after diagnosis) underwent a second craniotomy for tumour removal before dissemination, while none of the 15 patients with early dissemination did. Survival after diagnosis in patients with dissemination was shorter, although statistically not significant, than that of patients without dissemination. Survival after dissemination was limited in all patients (mean 19 weeks, range 2-39 weeks). Immunohistochemical study revealed that the disseminated tumour expressed less glial fibrillary acidic protein than the primary tumour. Our results suggest that dissemination does not seem to result from extended survival of the patients, but may occur at any time in malignant gliomas. Some malignant gliomas, especially in younger patients, have a capability to acquire biological characteristics suitable for dissemination in the earlier stage of the disease.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Arita N,Taneda M,Hayakawa Tdoi
10.1007/BF01476415subject
Has Abstractpub_date
1994-01-01 00:00:00pages
84-92issue
2-4eissn
0001-6268issn
0942-0940journal_volume
126pub_type
杂志文章abstract:BACKGROUND:This prospective observational study was undertaken to investigate the advantages, the safety, and the drawbacks of reconstructing a cervical corpectomy with a distractible corpectomy cage. According to the author's literature search, this is the second clinical report on a distractible cervical corpectomy c...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0871-9
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To establish the risk of recurrence in patients with chronic subdural hematoma (cSDH) on antithrombotic treatment (AT, i.e., antiplatelets and anticoagulants). Secondary end points were perioperative morbidity and mortality between groups (AT vs. no-AT group) and exploration if timing of resumption of AT trea...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3330-x
更新日期:2017-11-01 00:00:00
abstract::Lesions generated by the passage of micro-needles through vessel walls are of concern because any lesion may significantly alter hemodynamics of an anastomosis. To study this problem, three different needles were tested on the exposed carotid arteries of 30 rats: the 100 mu taper point, the 100 mu cutting point, and t...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01402308
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Z-L response (ZLR) has been suggested to a new electromyographic (EMG) potential recorded from the facial muscle of patient with hemifacial spasm (HFS) during microvascular decompression (MVD). Although ZLR has been suggested to be useful, experience of ZLR monitoring is limited and its significance during M...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3462-z
更新日期:2018-05-01 00:00:00
abstract::Does the absolute value of the stump pressure (post-occlusion back pressure) become a useful index of a good collateral circulation? The authors continuously monitored the mean arterial pressure before, during and after 20-minute balloon test occlusion in 24 patients. The stump pressure was then compared with the resu...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411175
更新日期:1996-01-01 00:00:00
abstract::In 17 primary transnasal operations on Nelson tumours long-term results are assessed measuring ACTH plasma levels and performing regular neuroradiological controls. In small intrasellar adenomas only one recurrent ACTH elevation near to pretreatment levels without symptoms from tumour growth was observed after 10 year...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405437
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Early recognition of emerging delayed neurological deficits (DND) in patients after subarachnoid haemorrhage (SAH) is not always possible by transcranial Doppler sonography. Aim of this study was to investigate a) whether determination of blood flow velocities in deep cerebral basal veins can predict DND in ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010170033
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:The management of pineal cysts is still debatable, especially for asymptomatic incidental ones. For symptomatic cysts associated with hydrocephalus, the surgical management is mandatory and may include either classical microsurgical approaches to the pineal region or endoscopic trans-ventricular approaches i...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1849-z
更新日期:2013-10-01 00:00:00
abstract:STUDY DESIGN:Spinal subarachnoid hematomas are unusual and difficult to diagnose and the outcome of treatment is influenced by the lesions that frequently accompany them. OBJECTIVES:To clarify the neuroradiological diagnostic aspects of spinal subarachnoid hematoma as well as the results of treatment. BACKGROUND:Only...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-004-0458-2
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:The mechanisms underlying post-extracranial to intracranial (EC-IC) bypass neurocognitive changes are poorly understood. METHODS:Data from 55 patients who underwent a unilateral EC-IC bypass for atherosclerotic internal carotid artery (ICA)/middle cerebral artery (MCA) steno-occlusive disease were retrospec...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2620-4
更新日期:2016-01-01 00:00:00
abstract::One case of a pontine haematoma with clinical symptoms of cerebellopontine angle tumour is described. The haematoma was successfully evacuated, and preoperative neurological deficits disappeared except for minimal right fifth nerve palsy. The pathological specimen was diagnosed as arteriovenous malformation. Lateropon...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02055855
更新日期:1983-01-01 00:00:00
abstract::Niravoline is a selective kappa-opioid receptor agonist. Its effect on tumour-origin brain oedema was investigated in a brain tumour model created by implantation of C6 glioma cells into the brain of Wistar rats. Five weeks after the tumour cell implantation, niravoline was administered i.v. at 1 mg/kg, a total of fou...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050374
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:The de novo development of an aneurysm in an previously normal artery is an uncommon event. We describe a patient who developed a de novo bleeding aneurysm of the basilar artery in the three weeks following the surgical removal of a large cerebellar AVM. METHOD-FINDINGS: A 48-year-old man suddenly developed ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0125-z
更新日期:2003-12-01 00:00:00
abstract::We estimated the volume doubling time (Vd) of the ethyl-nitrosourea-induced rat glioma by serial magnetic resonance imaging, and the results were compared with potential doubling time (Tp) determined immunohistochemically. Vd ranged from 3.3 to 29.2 days (11.3 +/- 7.74) and Tp ranged from 2.3 to 13.3 days (6.81 +/- 3....
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050148
更新日期:1998-01-01 00:00:00
abstract::In human brain tumours the extension of peritumoural brain oedema may vary considerably. 37 brain tumours of various pathology and 2 abscesses were examined to identify the factors and mechanisms responsible for the oedema spreading. Peritumoural oedema profiles were determined towards the white matter and ventricle b...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01793077
更新日期:1988-01-01 00:00:00
abstract::In spite of the recent advances in neuroradiology including the CT scan and the spin-echo-magnetic resonance (MR), accurate diagnosis of arteriovenous malformations (AVMs) involving the spinal cord is still based on selective angiography. This last procedure is invasive and needs to be repeated during the follow up. P...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01476287
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The natural history of vertebrobasilar artery dissection (VAD) is not fully known. The purpose of this study was to review the clinical outcome of the patients with VAD, then to propose an appropriate management strategy for VAD. METHOD:From 1992 to 2004, 35 VAD patients admitted to our institutes were retr...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0742-4
更新日期:2006-04-01 00:00:00
abstract::Nine cases of posttraumatic primary brain stem haematoma are described. All cases presented ocular and vegetative symptoms. Hyperextension was regarded as the most likely mechanism of injury. All patients were treated conservatively; half of them with a good outcome. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01428496
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:To investigate whether patients with critical emergency conditions are seeking or receiving the medical care that they require, we characterized the reality of care for patients presenting with neuro-emergencies during the first phase of the COVID-19 pandemic. METHODS:In this observational, longitudinal coh...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-020-04437-z
更新日期:2020-08-01 00:00:00
abstract::This report describes a rare case of a distal anterior choroidal artery aneurysm which developed intraventricular haemorrhage without subarachnoid haemorrhage as shown on computerized tomographic (CT) scan. A 69-year-old hypertensive man suddenly became unconscious. An emergency CT scan showed a severe intraventricula...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s007010050082
更新日期:1998-01-01 00:00:00
abstract::A 34-year-old female patient suffering from right-sided facial palsy presented to our hospital. Her hearing range was within normal limits. She had undergone GKS after receiving a diagnosis of facial nerve schwannoma (FNS). On the fourth day after GKS, the patient experienced sudden onset hearing loss on the right sid...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1983-7
更新日期:2014-02-01 00:00:00
abstract::Octreotide is a potent agonist of somatostatin that lowers the serum level of growth hormone (GH), and reduces the size of somatotropinomas. However, the detailed mechanism of shrinkage of this tumour is not known. We, therefore, evaluated 11 patients with somatotropinomas who were treated with octreotide 300 microgra...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411403
更新日期:1997-01-01 00:00:00
abstract::A lateral route between the SCM and the lateral border of the internal jugular vein is defined from an anatomical study for exposure of the VA. It offers the simplest route for controlling any part or the whole length of the VA, including its intracranial portion. Surgical indications are discussed on the basis of our...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406753
更新日期:1980-01-01 00:00:00
abstract::The authors report on two types of carotid-A(1) junctional aneurysms projecting backwards. In the two A(1)-type examples, the aneurysm originated at the posterior wall of the proximal A(1) joining the carotid termination and could be clipped using an ipsilateral pterional approach. However, in the carotid-type example...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-007-1223-0
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Microvascular decompression (MVD) for hemifacial spasm (HFS) has been popular, but it may take enough time to master this special operative technique and procedure. This may induce uneven distribution of the number of MVD operations in each institute, possibly resulting in an overall unsatisfactory quality o...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1724-y
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Several models for the application of intra-operative magnetic resonance imaging (IMRI) have recently been reported, most of them unique. Two fundamental issues need to be addressed: optimal use of the scanner to ensure a wide base for research, development and clinical application, and an organisational mod...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010200035
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:The suprameatal tubercle (SMT) may obscure the neurovascular compression (NVC) in microvascular decompression (MVD) for trigeminal neuralgia (TGN). The aim of this study is to address the necessity of resecting SMT in MVD for TGN. METHODS:We retrospectively analyzed radiological findings of 461 MVDs in pati...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-020-04242-8
更新日期:2020-05-01 00:00:00
abstract::In the present note, the cause of root compression in cases with degenerative lumbar spondylolisthesis is discussed in order to clarify the best method of surgery and to avoid iatrogenic damage of the cauda equina if a transpedicular fusion is going to be performed. The root compression is due to osteophytes growing o...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02187192
更新日期:1995-01-01 00:00:00
abstract::Too few cases of isolated abducent nerve palsy caused by neurovascular compression syndrome have been reported. We here report on a case of abducent nerve palsy caused by neurovascular compression syndrome that was successfully treated by microvascular decompression (MVD). A 46-year-old male presented with a 6-month h...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-015-2530-5
更新日期:2015-10-01 00:00:00
abstract::Forty one cases of subdural empyema treated between 1977 and 1988 at the Postgraduate Institute of Medical Education and Research. Chandigarh, have been analysed. The patients ranged from 9 days to 80 years of age. There were 22 children, including 11 infants. Fever, altered sensorium and seizures were the most common...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/BF01402182
更新日期:1990-01-01 00:00:00