Olfactory bulb and tract and temporal lobe volumes. Normative data across decades.

Abstract:

:The sense of smell shows a diminution with age as measured by the University of Pennsylvania Smell Identification Test (UPSIT). To ascertain whether the volumes of the olfactory bulbs and tracts (OBTs) and the temporal lobes (TL) declined in parallel to smell function, we examined 36 individuals from ages 22 to 78 who did not complain of any loss of the sense of smell using magnetic resonance (MR) imaging. The OBT volumes showed an initial increase to the 4th decade of life and then a decrease with increasing age, while the trend in TL volume was not as dramatic. There was no correlation between OBT or TL volumes with unilateral or total UPSIT scores. The normative data by decades can be used to assess the OBTs of cohorts of patients with neurodegenerative disorders that affect olfaction.

journal_name

Ann N Y Acad Sci

authors

Yousem DM,Geckle RJ,Bilker WB,Doty RL

doi

10.1111/j.1749-6632.1998.tb10624.x

subject

Has Abstract

pub_date

1998-11-30 00:00:00

pages

546-55

eissn

0077-8923

issn

1749-6632

journal_volume

855

pub_type

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