Relationship between inappropriate left ventricular hypertrophy and ejection fraction independent of absolute or indexed mass in a community sample of black African ancestry.

abstract：BACKGROUND:The Fas-Fas ligand (FasL) system is involved in apoptosis in many types of cells. Recently, the expression of FasL on endothelial cells was reported. FasL is cleaved by a metalloproteinase and released in serum as soluble FasL (sFasL). Vasoactive substances, including metalloproteinase, are modulated by endo...

journal_title：Journal of hypertension

authors： Okura T,Watanabe S,Jiang Y,Nakamura M,Takata Y,Yang ZH,Kohara K,Kitami Y,Hiwada K

更新日期：2002-05-01 00:00:00

abstract：:The fall in blood pressure that is commonly observed when groups of hypertensive individuals are followed without treatment is usually ascribed to two sources: regression towards the mean and increasing familiarity of the subject with the assessment process. Any effect of the latter process could bias the results of c...

journal_title：Journal of hypertension

authors： Haynes RB,Logan AG,Flanagan PT,Milne BJ

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:We examined whether the early initiation of sexual activity is associated with hypertension in US adults, and whether the timing of first menstruation is meaningful in regard of this association. We also assessed the effect modification by ethnicity. METHODS:Using data from 2001 to 2016 National Health and ...

journal_title：Journal of hypertension

authors： Ngueta G,Ndjaboue R

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Underlying pathophysiology of orthostatic hypotension has been poorly understood. We hypothesized that aortic pulse pressure (APP) reflecting aortic stiffness may be involved in the development of orthostatic hypotension. METHODS:A total of 200 patients (age 64.3 ± 10.9 years, 62.5% men) who underwent invasi...

journal_title：Journal of hypertension

authors： Chung J,Kim HL,Lim WH,Seo JB,Kim SH,Zo JH,Kim MA

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Increased arterial stiffness is associated with cardiovascular morbidity and mortality among hypertensive patients. OBJECTIVES:To assess the relationship between ambulatory arterial stiffness index (AASI) and subclinical left ventricular (LV) systolic dysfunction assessed by 2-D speckle-tracking echocardiog...

journal_title：Journal of hypertension

authors： Ahmed TAN,Shams-Eddin H,Fathy MA,El-Naggar HM,Kishk YT

更新日期：2020-05-01 00:00:00

abstract：:Medical records were examined for 1935 patients who presented sequentially to a hypertension clinic between 1971 and 1981. Patients were classified according to whether they were on a beta-blocker, methyldopa, a potassium-losing diuretic, or whether they had discontinued any of these treatments. Age-standardized morta...

journal_title：Journal of hypertension

authors： Franks PJ,Hartley K,Bulpitt PF,Bulpitt CJ,Dollery CT

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:A recent editorial published by Verma and Strauss, entitled 'Angiotensin receptor blockers and myocardial infarction', examined, through a partial analysis of individual trials, the use of angiotensin receptor blockers (ARBs) in a variety of clinical settings. This editorial was reported widely in the lay pr...

journal_title：Journal of hypertension

authors： Volpe M,Mancia G,Trimarco B

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:In clonal animal cells, certain angiotensin receptor blockers (ARB) activate the peroxisome proliferator-activated receptor-gamma (PPARgamma). The aim of this work was to validate that observation in human cells and humans. METHODS:We investigated the induction of in-vitro adipogenesis and the activation of ...

journal_title：Journal of hypertension

authors： Janke J,Schupp M,Engeli S,Gorzelniak K,Boschmann M,Sauma L,Nystrom FH,Jordan J,Luft FC,Sharma AM

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:Anemia is common in patients with heart failure and several factors have been thought to cause anemia in heart failure. Despite vigorous studies, the mechanism underlying the pathophysiology of anemia in heart failure is unknown. We investigated the iron regulating system in Dahl salt-sensitive heart failure ...

journal_title：Journal of hypertension

authors： Naito Y,Tsujino T,Fujimori Y,Sawada H,Akahori H,Hirotani S,Ohyanagi M,Masuyama T

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Preeclampsia is associated with an elevated risk of cardiovascular disease later in life. Women with a history of preeclampsia are at risk of developing hypertension as well as ischemic heart disease. Identification of women at the highest risk is important to initiate preventive strategies. We investigated w...

journal_title：Journal of hypertension

authors： Muijsers HEC,Westermann D,Birukov A,van der Heijden OWH,Drost JT,Kräker K,Haase N,Müller DN,Herse F,Maas AHEM,Dechend R,Zeller T,Roeleveld N

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the influence of renal sympathetic nerves on the production of interleukin (IL)-6 in the kidney of normotensive Wistar rats and spontaneously hypertensive rats (SHR). DESIGN:In acute studies, the left kidney was exposed and the renal nerves were electrically stimulated to...

journal_title：Journal of hypertension

authors： Nakamura A,Kohsaka T,Johns EJ

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:It has been postulated that hypertension in the spontaneously hypertensive rat (SHR) results from autoimmune damage to the SHR vasculature. The objective of this study was to isolate autoreactive T-cells specific for arterial antigens, and to characterize these cells. DESIGN:The presence of autoreactive T-ce...

journal_title：Journal of hypertension

authors： Ofosu-Appiah W,Ruggiero C,Huang LY

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Several cytokines and adhesion molecules released from endothelium play an important role in inflammation, immune responses, and probably atherogenesis. OBJECTIVE:To determine whether the transcription factor nuclear factor-kappaB mediated expression of these genes involved in the inflammatory response of e...

journal_title：Journal of hypertension

authors： Tomita N,Morishita R,Tomita S,Yamamoto K,Aoki M,Matsushita H,Hayashi S,Higaki J,Ogihara T

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Results from previous studies suggested that a blunted response of renal plasma flow (RPF) to angiotensin II infusion during a high-sodium diet (a phenotype associated with nonmodulation) is an intermediate phenotype for essential hypertension. OBJECTIVE:To determine whether RPF traits used to investigate n...

journal_title：Journal of hypertension

authors： Kardia SL,Sing CF,Turner ST

更新日期：1997-05-01 00:00:00

abstract：DESIGN:Because of uncertainties regarding the complete antihypertensive mechanism of action of beta-adrenoceptor antagonists, the present study determined whether vagal afferent neurons of humans and rats possess beta-adrenoceptors. Such a location would provide an appropriate target for beta-blockers to modulate neuro...

journal_title：Journal of hypertension

authors： Lawrence AJ,Watkins D,Jarrott B

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVES:Angiotensin converting enzyme (ACE) inhibitors reduce neointimal hyperplasia after balloon denudation, but the mechanisms are not completely understood. It has been demonstrated that nuclear oncogenes are induced in the vascular wall in the hours immediately after injury, and that the same genes are induced ...

journal_title：Journal of hypertension

authors： Van Belle E,Bauters C,Wernert N,Delcayre C,McFadden EP,Dupuis B,Lablanche JM,Bertrand ME,Swynghedauw B

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:In arteries, agonists such as acetylcholine release an endothelium-derived hyperpolarizing factor (EDHF) that is neither nitric oxide nor prostacyclin. OBJECTIVES:To examine the responses to acetylcholine in segments of forearm veins from patients with chronic renal failure who either had never received dia...

journal_title：Journal of hypertension

authors： Martinez-León JB,Segarra G,Medina P,Vila JM,Lluch P,Peiró M,Otero E,Lluch S

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:This controlled trial assessed the effect of continuous positive airway pressure (CPAP) on blood pressure (BP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH). METHODS:We evaluated 96 patients with resistant hypertension, defined as clinic BP at least 140/90 mmHg despite treat...

journal_title：Journal of hypertension

authors： Lozano L,Tovar JL,Sampol G,Romero O,Jurado MJ,Segarra A,Espinel E,Ríos J,Untoria MD,Lloberes P

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:Endothelial dysfunction is associated to cardiovascular risk factors and predicts cardiovascular events. Peripheral arterial tonometry (PAT) is a novel noninvasive method to assess endothelial function. However, there is a paucity of data about its reproducibility. The aim of this study was to assess the fea...

journal_title：Journal of hypertension

authors： Brant LC,Barreto SM,Passos VM,Ribeiro AL

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Mineralocorticoid receptor antagonists are increasingly used in patients with treatment-resistant hypertension (TRH). There is experimental evidence for blood pressure (BP) independent effects of mineralocorticoid receptor blockade on cardiovascular target organ damage. We hypothesized that low-dose eplereno...

journal_title：Journal of hypertension

authors： Schneider A,Schwab J,Karg MV,Kalizki T,Reinold A,Schneider MP,Schmieder RE,Schmidt BM

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:Recent studies in homogenized hearts suggest that chymase rather than angiotensin converting enzyme (ACE) is responsible for cardiac angiotensin I to angiotensin II conversion. We investigated in intact rat hearts whether (i) enzymes other than ACE contribute to angiotensin I to angiotensin II conversion and...

journal_title：Journal of hypertension

authors： de Lannoy LM,Schuijt MP,Saxena PR,Schalekamp MA,Danser AH

更新日期：2001-05-01 00:00:00

abstract：:We have studied the norepinephrine (NE) uptake processes directly in synaptosomes isolated from the hypothalamus of both Dahl salt-sensitive (DS) and Dahl salt-resistant (DR) rats. Both DS and DR rats were divided into two dietary groups, one high salt diet group and one low salt diet group. NE uptake was highly sodiu...

journal_title：Journal of hypertension

authors： Rho JH,Hough K

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVES:The interactions between eNOS or oxidative stress and bradykinin under long-term treatment of angiotensin II type 1 receptor antagonists (ATRA) remain unknown. To elucidate the molecular mechanisms of the cardioprotective effect of ATRA, we evaluated whether valsartan affects the bradykinin-eNOS and nicotina...

journal_title：Journal of hypertension

authors： Yoshida K,Kobayashi N,Ohno T,Fukushima H,Matsuoka H

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Blood pressure changes during menopausal transition have not been studied previously using a biracial sample. We investigated whether menopausal transition was associated with change in blood pressure in African-American or white women. DESIGN, SETTING AND PARTICIPANTS:The prospective multicenter study, the ...

journal_title：Journal of hypertension

authors： Luoto R,Sharrett AR,Schreiner P,Sorlie PD,Arnett D,Ephross S

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The effect of brief, prehypertensive therapy by angiotensin-converting enzyme inhibition (ACEi) with perindopril on the structure and function of large arteries was studied in rats. METHODS:Spontaneously hypertensive rats (SHR) received perindopril (3 mg/kg per day) between the ages of either 6 and 10 weeks ...

journal_title：Journal of hypertension

authors： Ng K,Butlin M,Avolio AP

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To determine whether the noradrenergic sympathetic hyperinnervation in the spontaneously hypertensive rat (SHR), a genetic model of essential hypertension, is associated with changes in neurotrophin 3 (NT3) concentrations. METHODS:NT3 levels were measured using a sensitive enzyme-linked immunosorbent assay (...

journal_title：Journal of hypertension

authors： Zhang SH,Rush RA

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:Adenosine dilates rabbit renal arteries by an endothelium-dependent, nitric oxide (NO)- and prostaglandin-independent mechanism. The aim was to identify the responsible P1-purinoceptor subtype and to investigate the involvement of K+-channels. METHODS:Rabbit renal arteries were perfused with medium containin...

journal_title：Journal of hypertension

authors： Rump LC,Jabbari-T J,von Kügelgen I,Oberhauser V

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:There is a need for an easily accessible biomarker of sympathetic nervous activation in essential hypertension, but none exists. Heart rate (HR) has been suggested, but requires validation, now doubly important as an elevated HR in hypertension has emerged as an independent cardiovascular risk factor. METHO...

journal_title：Journal of hypertension

authors： Esler M,Lambert G,Esler D,Ika Sari C,Guo L,Jennings G

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:High blood pressure is known to be associated with higher cardiovascular risk. The emphasis has shifted over time from diastolic pressure to systolic pressure and variability in blood pressure. This study examined the impact of transient and sustained diastolic hypertension on later mortality. METHODS:In th...

journal_title：Journal of hypertension

authors： Peters R,Wells F,Bulpitt C,Beckett N

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to define the relationship between physical activity and the magnitude of the percentage fall in blood pressure at night (nocturnal dip). METHODS:We simultaneously monitored 24-h ambulatory blood pressure and measured physical activity by actigraphy in 434 patients. Blood pressure w...

journal_title：Journal of hypertension

authors： Leary AC,Donnan PT,MacDonald TM,Murphy MB

更新日期：2000-04-01 00:00:00