Elective surgery without transfusion: influence of preoperative hemoglobin level and blood loss on mortality.

Abstract:

:To clarify the widespread practice of preoperative transfusion to attain a 10 g/dL level of hemoglobin, the relationship between preoperative hemoglobin level, operative blood loss, and mortality was studied by analyzing the results of 113 operations in 107 consecutive Jehovah's Witness patients who underwent major elective surgery. Ninety-three patients had preoperative hemoglobin values greater than 10 g/dL; 20 had preoperative hemoglobin levels between 6 to 10 g/dL. Mortality for preoperative hemoglobin levels greater than 10 g/dL was 3 of 93 (3.2%); for preoperative hemoglobin levels between 6 to 10 g/dL, mortality was 1 of 20 (5%). Mortality was significantly increased with an estimated blood loss of greater than 500 mL, regardless of the preoperative hemoglobin level (p less than 0.025). More importantly, there was no mortality if estimated blood loss was less than 500 mL, regardless of the preoperative hemoglobin level. From these data, we conclude that: (1) Mortality in elective surgery appears to depend more on estimated blood loss than on preoperative hemoglobin levels; and (2) Elective surgery can be done safely in patients with a preoperative hemoglobin level as low as 6 g/dL if estimated blood loss is kept below 500 mL.

journal_name

Am J Surg

authors

Spence RK,Carson JA,Poses R,McCoy S,Pello M,Alexander J,Popovich J,Norcross E,Camishion RC

doi

10.1016/s0002-9610(05)81227-9

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

320-4

issue

3

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(05)81227-9

journal_volume

159

pub_type

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