Quo vadis older keratoconus patients? Do they die at younger ages?

abstract：PURPOSE:To review the development of artificial corneas (prostheses and tissue equivalents) for transplantation, and to provide recent updates on our tissue-engineered replacement corneas. METHODS:Modified natural polymers and synthetic polymers were screened for their potential to replace damaged portions of the huma...

journal_title：Cornea

authors： Griffith M,Hakim M,Shimmura S,Watsky MA,Li F,Carlsson D,Doillon CJ,Nakamura M,Suuronen E,Shinozaki N,Nakata K,Sheardown H

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:The objective of this study was to produce a porcine corneal acellular matrix (ACM) and assess its possibility for biomedical applications. METHODS:Porcine corneas were treated with various concentrations of sodium dodecylsulfate for different lengths of time. Optimal conditions for processing the ACM were not...

journal_title：Cornea

authors： Zhou Y,Wu Z,Ge J,Wan P,Li N,Xiang P,Gao Q,Wang Z

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To assess the long-term clinical course of dry eye in patients with chronic graft-versus-host disease (cGVHD). METHODS:A prospective case series of 49 patients with cGVHD was conducted. Complete history and ophthalmic examination were performed at baseline and at 36 months (range, 26-53). All patients received...

journal_title：Cornea

authors： Sáles CS,Johnston LJ,Ta CN

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To retrospectively evaluate the coexistence of congenital glaucoma with congenital hereditary endothelial dystrophy. METHODS:Ten infants presented to our hospital with diffuse corneal edema and bilaterally elevated intraocular pressure (IOP). These patients were diagnosed with congenital glaucoma. All patients...

journal_title：Cornea

authors： Ramamurthy B,Sachdeva V,Mandal AK,Vemuganti GK,Garg P,Sangwan VS

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To describe a patient whose Descemet membrane detachment following deep lamellar keratoplasty failed to respond to 2 attempts at gas tamponade but later resolved spontaneously. METHODS:A 77-year-old woman with bilateral anterior corneal stromal scarring underwent a right deep lamellar keratoplasty with the Mel...

journal_title：Cornea

authors： Tu KL,Ibrahim M,Kaye SB

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To examine the immediate effect of ocular rubbing on corneal topography. METHODS:Corneal topography and analysis were performed before, immediately after, and 5 minutes after eyelid rubbing in 29 volunteers without ocular disease. RESULTS:The surface regularity index increased from a baseline of 0.24 to 0.91 ...

journal_title：Cornea

authors： Mansour AM,Haddad RS

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:To investigate the severity of keratoconus in terms of corneal elevation differences with 2 different reference surfaces using topographic analysis. METHODS:Eighty-six eyes of 50 patients with keratoconus of various clinical stages (61 male and 25 female eyes) with mean age of 37.3 ± 11.6 years were evaluated....

journal_title：Cornea

authors： Ishii R,Kamiya K,Igarashi A,Shimizu K,Utsumi Y,Kumanomido T

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To assess the morphologic differences of three types of lattice corneal dystrophies (LCDs) from histologic, immunohistochemical, and ultrastructural studies. METHODS:Corneas from three patients, one LCD1, one His626Arg-LCD, and one LCD3A were processed for Congo red, betaig-h3(541-564) antibodies immunostainin...

journal_title：Cornea

authors： Schmitt-Bernard CF,Schneider C,Argilés A

更新日期：2002-07-01 00:00:00

abstract：:Although corneal epithelial stem cells (SCs) are located at the limbus between the cornea and the conjunctiva, not all limbal basal epithelial cells are SCs. Using 2 dispase digestions to remove different amounts of limbal basal epithelial cells for cross-sections, flat mounts, and cytospin preparations, double immuno...

journal_title：Cornea

authors： Hayashida Y,Li W,Chen YT,He H,Chen SY,Kheirkah A,Zhu YT,Matsumoto Y,Tseng SC

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To evaluate the association between keratoconus (KC) and immune disorders (IDs). METHODS:A retrospective observational case-control study of all the members in the Central District of Clalit Health Services in Israel who were diagnosed to have KC (years 2000-2007; n = 426) and 1704 age- and gender-matched cont...

journal_title：Cornea

authors： Nemet AY,Vinker S,Bahar I,Kaiserman I

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...

journal_title：Cornea

authors： El-Massry AA,Goweida MB,Shama Ael-S,Elkhawaga MH,Abdalla MF

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:Clinical research addressing the issue of donor globe decontamination is yet to establish convincing data for the optimal choice of an antimicrobial agent. METHODS:In a donor-globe decontamination study, the antimicrobial effectiveness of a fluoroquinolone antibiotic (ciprofloxacin, 0.3%) was evaluated for the...

journal_title：Cornea

authors： Gopinathan U,Reddy MK,Nadkarni MS,Dasari S,Rao GN

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:To determine the factors associated with clinically significant dry eye after keratorefractive surgery. METHODS:This is a large database retrospective study that included consecutive cases of myopic laser in situ keratomileusis (LASIK) or photorefractive keratectomy performed between 2008 and 2016 at Care-Visi...

journal_title：Cornea

authors： Shehadeh-Mashor R,Mimouni M,Shapira Y,Sela T,Munzer G,Kaiserman I

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The 27-kDa heat shock protein (HSP27) has been implicated in wound healing in multiple tissues. We investigated the expression and localization of phosphorylated HSP27 during epithelial wound healing in the murine cornea. METHODS:Corneas of 8- to 10-week-old C57BL6 mice were wounded by epithelial debridement (...

journal_title：Cornea

authors： Jain S,De la Cruz J,Kang E,Kojima T,Chang JH,Kim JY

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To evaluate changes in the donor corneal endothelium in the intact globe and in the in vivo rabbit cornea to characterize more fully the formation of "dark events" without relief images in the endothelial mosaic. METHODS:Six ex vivo human donor corneas in the intact globe and an in vivo rabbit model were used ...

journal_title：Cornea

authors： Nartey IN,Cavanagh HD,Jester JV,Andrews P,Petroll WM

更新日期：1998-09-01 00:00:00

abstract：:To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue stainin...

journal_title：Cornea

authors： Weiss JS,Orlando F,Albert DM

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To report intraocular lens (IOL) power calculation in 2 eyes that were highly undercorrected by previous myopic automated lamellar keratoplasty (ALK). METHODS:A 35-year-old man underwent bilateral myopic ALK, which caused high residual myopia (-9.0 -4.0 x 171 and -9.5 -4.5 x 74). The patient then underwent cat...

journal_title：Cornea

authors： Lee SH,Tsai CY,Liou SW,Tsai RJ,Ho JD

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Peters anomaly is the most common cause of congenital corneal opacities. Although conservative management is often ineffective except in mild cases, surgical intervention in the form of penetrating keratoplasty is fraught with unpredictability and often has unacceptable postoperative outcomes. As such, there is...

journal_title：Cornea

authors： Soh YQ,Mehta JS

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To describe cataract extraction and intraocular lens placement in a patient with an existing Type I Boston keratoprosthesis. METHODS:Case report to describe the surgical technique used to remove a cataract that developed after Boston keratoprosthesis placement. RESULTS:Extracapsular cataract extraction by usi...

journal_title：Cornea

authors： Harissi-Dagher M,Colby KA

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:The efficacy of gene therapy using nonviral vector based on polyplex micelle has been studied against corneal neovascularization in mice. METHODS:A block copolymer, poly(ethylene glycol) (PEG)-block-polycation carrying ethylenediamine units in the side chain (PEG-b-P[Asp(DET)]), was prepared. PEG-b-P[Asp(DET)]...

journal_title：Cornea

authors： Iriyama A,Usui T,Yanagi Y,Amano S,Oba M,Miyata K,Nishiyama N,Kataoka K

更新日期：2011-12-01 00:00:00

abstract：:An 81-year-old man with metastatic prostate carcinoma underwent a penetrating keratoplasty for phlyctenular keratitis. Two years later he developed a fleshy, vascular mass in the superotemporal corneal graft wound, at the site of prior graft sutures. An excisional biopsy of the mass was performed to rule out metastati...

journal_title：Cornea

authors： De Potter P,Tardio DJ,Shields CL,Shields JA

更新日期：1992-11-01 00:00:00

abstract：PURPOSE:To evaluate visual, refractive, and corneal topography outcomes in eyes with keratoconus that have undergone exchange/adjustment surgery with a new intrastromal corneal ring segment (ICRS) combination after unsuccessful visual and/or refractive outcomes after primary ICRS surgery. METHODS:A retrospective nonra...

journal_title：Cornea

authors： Monteiro T,Mendes JF,Faria-Correia F,Franqueira N,Madrid-Costa D,Alfonso JF

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Patients undergoing primary pterygium excision with autologous conjunctival autograft and human tissue adhesive in New Zealand, currently receive subconjunctival anesthesia with oral postoperative analgesia for pain. Our aim was to investigate the potential added benefit of intraoperative subtenon bupivacaine t...

journal_title：Cornea

authors： Bhikoo R,Hughes K,Vather R,Murphy C

更新日期：2019-08-01 00:00:00

abstract：:Phacoemulsification has become the most commonly used procedure in cataract surgery owing to the development of new devices and surgical techniques; however, corneal endothelial damage still represents a serious complication. Although several factors are known to cause corneal endothelial damage, effects of irrigating...

journal_title：Cornea

authors： Takahashi H

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:This study was designed to report a case of acanthamoeba keratitis in a 5-year-old child without a history of trauma or contact lens usage. METHODS:The history, clinical presentation, diagnostic, and therapeutic approaches were reviewed. RESULTS:A 5-year-old child without any history of trauma or contact lens...

journal_title：Cornea

authors： Demirci G,Ay GM,Karabas LV,Altintas O,Tamer GS,Cağlar Y

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:To report a case of successful medical treatment with oral posaconazole in refractory fungal keratitis caused by Paecilomyces lilacinus. METHODS:Case report. RESULTS:A 57-year-old male, soft contact lens wearer presented with irritation, pain, photophobia, and reduced vision. Slit-lamp examination showed a la...

journal_title：Cornea

authors： Arnoldner MA,Kheirkhah A,Jakobiec FA,Durand ML,Hamrah P

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:To report intraoperative and 1-year postoperative results of the pachy-bubble technique for deep anterior lamellar keratoplasty (DALK). METHODS:This prospective interventional case series included 110 eyes of 107 patients with anterior corneal pathology who underwent DALK, including 78 with keratoconus. Outcom...

journal_title：Cornea

authors： Ghanem RC,Bogoni A,Ghanem VC

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To describe a case of transient band-like keratopathy after ocular exposure to fluocinonide cream and ketoconazole shampoo. DESIGN:Observational case report. RESULTS:A 40-year-old patient presented with acute pain, photophobia, lacrimation, and redness in 1 eye. The symptoms began while using fluocinonide cre...

journal_title：Cornea

authors： Savage HI,Edgington B,Appel J

更新日期：2005-04-01 00:00:00

abstract：:We report the case of a 34-year-old man who had uncomplicated cataract surgery in his left eye. Medical history was significant for atopic dermatitis, requiring oral immunosuppressive medications. Two days after the surgery, the patient presented with pain, photophobia, decreased vision, and a small corneal abrasion. ...

journal_title：Cornea

authors： Patel NN,Teng CC,Sperber LT,Dodick JM

更新日期：2009-01-01 00:00:00