One if by land, two if by sea: signalling to the ranks with CSP and XIP.

abstract：:Transcription of flagellar genes in Caulobacter crecentus is programmed to occur during the predivisional stage of the cell cycle. The mechanism of activation of Class II flagellar genes, the highest identified genes in the Caulobacter flagellar hierarchy, is unknown. As a step toward understanding this process, we ha...

journal_title：Molecular microbiology

authors： Stephens CM,Shapiro L

更新日期：1993-09-01 00:00:00

abstract：:Bacillus subtilis responds to signals of environmental and metabolic stress by inducing over 40 general stress genes under the control of the sigma B transcription factor. sigma B activity is regulated post-translationally by a multi-component network composed of two coupled partner-switching modules, RsbX-RsbS-RsbT a...

journal_title：Molecular microbiology

authors： Akbar S,Kang CM,Gaidenko TA,Price CW

更新日期：1997-05-01 00:00:00

abstract：:We have cloned a gene encoding a polygalacturonase (PG) in the filamentous fungus Aspergillus niger RH5344. The structural gene comprises 1141 bp coding for 362 amino acids and the open reading frame is disrupted by one intron of 52 bp. Eukaryotic consensus sequences for transcription regulation are found only in devi...

journal_title：Molecular microbiology

authors： Ruttkowski E,Khanh NQ,Wientjes FJ,Gottschalk M

更新日期：1991-06-01 00:00:00

abstract：:Experimental evidence suggests that apicomplexan parasites possess bipartite promoters with basal and regulated cis-elements similar to other eukaryotes. Using a dual luciferase model adapted for recombinational cloning and use in Toxoplasma gondii, we show that genomic regions flanking 16 parasite genes, which encomp...

journal_title：Molecular microbiology

authors： Behnke MS,Radke JB,Smith AT,Sullivan WJ Jr,White MW

更新日期：2008-06-01 00:00:00

abstract：:The chaperone/usher (CU) pathway is a conserved bacterial secretion system that assembles adhesive fibres termed pili or fimbriae. Pilus biogenesis by the CU pathway requires a periplasmic chaperone and an outer membrane (OM) assembly platform termed the usher. The usher catalyses formation of subunit-subunit interact...

journal_title：Molecular microbiology

authors： Henderson NS,Ng TW,Talukder I,Thanassi DG

更新日期：2011-02-01 00:00:00

abstract：:Intimin and Invasin are prototypical inverse (Type Ve) autotransporters and important virulence factors of enteropathogenic Escherichia coli and Yersinia spp. respectively. In addition to a C-terminal extracellular domain and a β-barrel transmembrane domain, both proteins also contain a short N-terminal periplasmic do...

journal_title：Molecular microbiology

authors： Leo JC,Oberhettinger P,Chaubey M,Schütz M,Kühner D,Bertsche U,Schwarz H,Götz F,Autenrieth IB,Coles M,Linke D

更新日期：2015-01-01 00:00:00

abstract：:We report here the construction and analysis of insertional mutations in each of the three genes of the gltBDF operon and the nucleotide sequence of the region downstream from gltD. Two open reading frames were identified, the first of which corresponds to gltF. The gltB and gltD genes code for the large and small sub...

journal_title：Molecular microbiology

authors： Castaño I,Flores N,Valle F,Covarrubias AA,Bolivar F

更新日期：1992-09-01 00:00:00

abstract：:The level of DnaA, a key bacterial DNA replication initiation factor, increases during the Caulobacter swarmer-to-stalked transition just before the G1/S transition. We show that DnaA coordinates DNA replication initiation with cell cycle progression by acting as a global transcription factor. Using DnaA depletion and...

journal_title：Molecular microbiology

authors： Hottes AK,Shapiro L,McAdams HH

更新日期：2005-12-01 00:00:00

abstract：:Teichoic acids (TAs) are the most abundant glycopolymers in the cell wall of Listeria, an opportunistic Gram-positive pathogen that causes severe foodborne infections. Two different structural classes of Listeria TA exist: the polyribitolphosphate-based wall teichoic acid (WTA) that is covalently anchored to the pepti...

journal_title：Molecular microbiology

authors： Sumrall ET,Keller AP,Shen Y,Loessner MJ

更新日期：2020-03-01 00:00:00

abstract：:Listeria monocytogenes grows in the cytosol of mammalian cells and spreads from cell to cell without exiting the intracellular milieu. During cell-cell spread, bacteria become transiently entrapped in double-membrane vacuoles. Escape from these vacuoles is mediated in part by a bacterial phospholipase C (PC-PLC), whos...

journal_title：Molecular microbiology

authors： Marquis H,Hager EJ

更新日期：2000-01-01 00:00:00

abstract：:Natural competence in Streptococcus pneumoniae is regulated by a quorum-sensing mechanism consisting of a competence-stimulating peptide (CSP), its dedicated secretion apparatus (ComAB), its histidine kinase receptor (ComD) and a response regulator (ComE). In this report, we show that ComE is a DNA-binding protein tha...

journal_title：Molecular microbiology

authors： Ween O,Gaustad P,Håvarstein LS

更新日期：1999-08-01 00:00:00

abstract：:The AppA protein of Rhodobacter sphaeroides is unique in its ability to sense and transmit redox signals as well as light signals. By functioning as antagonist to the PpsR transcriptional repressor, it regulates the expression of photosynthesis genes in response to these environmental stimuli. Here we show binding of ...

journal_title：Molecular microbiology

authors： Han Y,Meyer MH,Keusgen M,Klug G

更新日期：2007-05-01 00:00:00

abstract：:We report here the cloning of the arginine repressor gene argR of Bacillus stearothermophilus and the characterization and purification to homogeneity of its product. The deduced amino acid sequence of the 16.8-kDa ArgR subunit shares 72% identity with its mesophilic homologue AhrC of Bacilus subtilis. Sequence analys...

journal_title：Molecular microbiology

authors： Dion M,Charlier D,Wang H,Gigot D,Savchenko A,Hallet JN,Glansdorff N,Sakanyan V

更新日期：1997-07-01 00:00:00

abstract：:We have followed the time-dependent transfection of Paramecium cells with a vector containing the gene of green fluorescent protein (GFP) attached to the C-terminus of the PtSERCA1 gene. The outlines of alveolar sacs (ASs) are labelled, as is the endoplasmic reticulum (ER) throughout the cell. When GFP fluorescence is...

journal_title：Molecular microbiology

authors： Hauser K,Pavlovic N,Klauke N,Geissinger D,Plattner H

更新日期：2000-08-01 00:00:00

abstract：:The ferric uptake regulator (Fur) protein is known to act as a Fe2+-dependent transcriptional repressor of bacterial promoters. Here, we show that, in Helicobacter pylori, Fur can mediate the regulation of iron-activated genes in contrast to classical Fur regulation, in which iron acts as a co-repressor. Inactivation ...

journal_title：Molecular microbiology

authors： Delany I,Spohn G,Rappuoli R,Scarlato V

更新日期：2001-12-01 00:00:00

abstract：:The genome of the malaria parasite Plasmodium falciparum contains several multicopy gene families, including var, rifin, stevor and Pfmc-2TM. These gene families undergo expression switching and appear to play a role in antigenic variation. It has recently been shown that forcing parasites to express high copy numbers...

journal_title：Molecular microbiology

authors： Howitt CA,Wilinski D,Llinás M,Templeton TJ,Dzikowski R,Deitsch KW

更新日期：2009-09-01 00:00:00

abstract：:Bacteria of Shigella spp. are responsible for shigellosis in humans. They use a type III secretion (TTS) system encoded by a 200 kb virulence plasmid to enter epithelial cells and trigger apoptosis in macrophages. This TTS system comprises a secretion apparatus, translocators and effectors that transit through this ap...

journal_title：Molecular microbiology

authors： Penno C,Sansonetti P,Parsot C

更新日期：2005-04-01 00:00:00

abstract：:The stable maintenance of low-copy-number plasmids requires active partitioning, with the most common mechanism in prokaryotes involving the ATPase ParA. ParA proteins undergo intricate spatiotemporal relocations across the nucleoid, dynamics that function to position plasmids at equally spaced intervals. This spacing...

journal_title：Molecular microbiology

authors： Howard M,Gerdes K

更新日期：2010-10-01 00:00:00

abstract：:Colonization of mucosal respiratory surfaces is a prerequisite for the human pathobiont Streptococcus pneumoniae (the pneumococcus) to cause severe invasive infections. The arsenal of pneumococcal adhesins interacts with a multitude of extracellular matrix proteins. A paradigm for pneumococci is their interaction with...

journal_title：Molecular microbiology

authors： Kanwal S,Jensch I,Palm GJ,Brönstrup M,Rohde M,Kohler TP,Somplatzki D,Tegge W,Jenkinson HF,Hammerschmidt S

更新日期：2017-09-01 00:00:00

abstract：:Bacterial surface layers (S-layers) are extracellular protein networks that act as molecular sieves and protect a large variety of archaea and bacteria from hostile environments. Atomic force microscopy (AFM) was used to asses the S-layer of Coryne-bacterium glutamicum formed of PS2 proteins that assemble into hexamer...

journal_title：Molecular microbiology

authors： Scheuring S,Stahlberg H,Chami M,Houssin C,Rigaud JL,Engel A

更新日期：2002-05-01 00:00:00

abstract：:Streptomyces lividans has a novel DNA modification, which sensitises its DNA to degradation during electrophoresis (the Dnd phenotype). The entire gene cluster (dnd) involved in this modification was localized on an 8 kb DNA fragment and was expressed in a S. lividans deletion mutant (dnd) and in several heterologous ...

journal_title：Molecular microbiology

authors： Zhou X,He X,Liang J,Li A,Xu T,Kieser T,Helmann JD,Deng Z

更新日期：2005-09-01 00:00:00

abstract：:The Escherichia coli Sm-like host factor I (Hfq) is thought to play direct and indirect roles in post-transcriptional regulation by targeting small regulatory RNAs and mRNAs. In this study, we have used proteomics to identify new mRNA targets of Hfq. We have identified 11 candidate proteins, synthesis of which was dif...

journal_title：Molecular microbiology

authors： Vecerek B,Moll I,Afonyushkin T,Kaberdin V,Bläsi U

更新日期：2003-11-01 00:00:00

abstract：:Protein translocation across the bacterial cytoplasmic membrane has been studied extensively in Escherichia coli. The identification of the components involved and subsequent reconstitution of the purified translocation reaction have defined the minimal constituents that allowed extensive biochemical characterization ...

journal_title：Molecular microbiology

authors： Manting EH,Driessen AJ

更新日期：2000-07-01 00:00:00

abstract：:Arsenic is the most ubiquitous environmental toxin. Here, we demonstrate that bacteria have evolved the ability to use arsenic to gain a competitive advantage over other bacteria at least twice. Microbes generate toxic methylarsenite (MAs(III)) by methylation of arsenite (As(III)) or reduction of methylarsenate (MAs(V...

journal_title：Molecular microbiology

authors： Chen J,Yoshinaga M,Rosen BP

更新日期：2019-02-01 00:00:00

abstract：:Initiation of Escherichia coli chromosome replication is controlled by the DnaA initiator protein. Both rifampicin-mediated inhibition of transcription and ppGpp-induced changes in global transcription stops replication at the level of initiation. Here, we show that continued DnaA protein synthesis allows for replicat...

journal_title：Molecular microbiology

authors： Riber L,Løbner-Olesen A

更新日期：2020-12-01 00:00:00

abstract：:In general, wild Escherichia coli strains can grow effectively under moderately acidic organic acid-rich conditions. We found that the Shiga Toxin-producing E. coli (STEC) O157:H7 NGY9 grows more quickly than a K-12 strain in Luria-Bertani (LB)-2-morpholinoethanesulphonic acid (MES) broth supplemented with acetic acid...

journal_title：Molecular microbiology

authors： Barua S,Yamashino T,Hasegawa T,Yokoyama K,Torii K,Ohta M

更新日期：2002-02-01 00:00:00

abstract：:PrkC was shown to be a eukaryotic-like (Hanks-type) protein kinase from Bacillus subtilis with a structural organization similar to that of the eukaryotic sensor Ser/Thr or Tyr kinases (e.g. the TGF beta or PDGF receptors). The molecule consists of a catalytic domain located in the cytoplasm, joined by a single transm...

journal_title：Molecular microbiology

authors： Madec E,Laszkiewicz A,Iwanicki A,Obuchowski M,Séror S

更新日期：2002-10-01 00:00:00

abstract：:In enteric bacteria, proteins of the Hha/YmoA family play a role in the regulation of gene expression in response to environmental factors. Interaction of both Hha and YmoA with H-NS has been reported, and an Hha/H-NS complex has been shown to modulate expression in Escherichia coli of the haemolysin operon of plasmid...

journal_title：Molecular microbiology

authors： Paytubi S,Madrid C,Forns N,Nieto JM,Balsalobre C,Uhlin BE,Juárez A

更新日期：2004-10-01 00:00:00

abstract：:We have built a homology model of the AAA domain of the ATP-dependent protease FtsH of Escherichia coli based on the crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein. The resulting model of the hexameric ring of the ATP-bound form of the AAA ATPase suggests a plausible mechan...

journal_title：Molecular microbiology

authors： Karata K,Verma CS,Wilkinson AJ,Ogura T

更新日期：2001-02-01 00:00:00

abstract：:Rpc25 is a strongly conserved subunit of RNA polymerase III with homology to Rpa43 in RNA polymerase I, Rpb7 in RNA polymerase II and the archaeal RpoE subunit. A central domain of Rpc25 can replaced the corresponding region of Rpb7 with little or no growth defect, underscoring the functional relatedness of these prot...

journal_title：Molecular microbiology

authors： Zaros C,Thuriaux P

更新日期：2005-01-01 00:00:00